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Tuberculosis Jiang Lihong Tianjin Medical University
Questions ,[object Object],[object Object],[object Object],[object Object]
Diagnostic tests and procedures the tuberculin test
The tuberculin test ,[object Object],[object Object],[object Object],[object Object]
Who need to take the tuberculin test ,[object Object],[object Object],[object Object],[object Object]
method ,[object Object],[object Object],[object Object]
tuberculin test is done on children
Site:volar surface of the forearm
Size:diameter 6-10mm
 
Within 48 to 72 hours, a positive TB skin test is marked by an area of reddish induration greater than 10 mm. It is the induration (firm bump) that is gently palpated that determines the size, not the area of redness. This reaction is slightly larger than the average positive test 17 mm in size. The positive reaction shown here was obtained with a TB skin test performed 20 years after the initial infection
 
 
[object Object],[object Object],[object Object],[object Object]
Assessment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
 
 
 
 
A negative reaction ,[object Object]
A negative reaction ,[object Object],[object Object],[object Object],[object Object],[object Object]
A negative reaction ,[object Object],[object Object],[object Object],[object Object],[object Object]
Studies indicated when the tuberculin test is positive ,[object Object],[object Object]
Identification of the tubercle bacillus by smear or culture ,[object Object],[object Object],[object Object]
sputum ,[object Object]
Gastric washings ,[object Object]
CSF ,[object Object]
Radiographic studies ,[object Object]
PCR ,[object Object]
What does having TB infection mean? ,[object Object]
Inactive TB germs can't hurt you now ...
What is TB disease? ,[object Object],[object Object]
... when body defenses are weakened, inactive TB germs become active and break out
case
Tuberculin test
Tuberculosis from sputum
Chest x-ray
Chest x-ray
treatment ,[object Object],[object Object],[object Object]
General care ,[object Object],[object Object],[object Object]
 
chemotherapy
Asymptomatic tuberculin-positive children and adolescents ,[object Object],[object Object],[object Object],[object Object]
Children and adolescents with symptomatic tuberculosis   ,[object Object],[object Object],[object Object]
Short-course chemotherapy ,[object Object],[object Object],[object Object]
Other drugs ,[object Object],[object Object],[object Object]
As same as INH po 10-15mg ETH Optic neuritis po 15-25mg EMB Hepatotoxic,hyperuricemia,arthralgia, po 20-30mg (≤750mg/d) PZA Nephrotoxic,hypersensitivity,fever im 20-30mg (≤750mg/d) SM Hepatotoxicity,nausea,vomit po 10mg(≤450mg/d) RFP Hepatotoxicity,peripheralneuritis,hypersensitivity,fever po (im, iv) 10mg(≤300mg/d) INH Main adverse reaction method Dosage(kg/d) drug
corticosteroid ,[object Object],[object Object]
immunization ,[object Object],[object Object],[object Object]
[object Object]
question ,[object Object],[object Object],[object Object],[object Object]
thanks

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Tuberculosis2

  • 1. Tuberculosis Jiang Lihong Tianjin Medical University
  • 2.
  • 3. Diagnostic tests and procedures the tuberculin test
  • 4.
  • 5.
  • 6.
  • 7. tuberculin test is done on children
  • 8. Site:volar surface of the forearm
  • 10.  
  • 11. Within 48 to 72 hours, a positive TB skin test is marked by an area of reddish induration greater than 10 mm. It is the induration (firm bump) that is gently palpated that determines the size, not the area of redness. This reaction is slightly larger than the average positive test 17 mm in size. The positive reaction shown here was obtained with a TB skin test performed 20 years after the initial infection
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  • 31.
  • 32.
  • 33.
  • 34. Inactive TB germs can't hurt you now ...
  • 35.
  • 36. ... when body defenses are weakened, inactive TB germs become active and break out
  • 37. case
  • 42.
  • 43.
  • 44.  
  • 46.
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  • 48.
  • 49.
  • 50. As same as INH po 10-15mg ETH Optic neuritis po 15-25mg EMB Hepatotoxic,hyperuricemia,arthralgia, po 20-30mg (≤750mg/d) PZA Nephrotoxic,hypersensitivity,fever im 20-30mg (≤750mg/d) SM Hepatotoxicity,nausea,vomit po 10mg(≤450mg/d) RFP Hepatotoxicity,peripheralneuritis,hypersensitivity,fever po (im, iv) 10mg(≤300mg/d) INH Main adverse reaction method Dosage(kg/d) drug
  • 51.
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  • 54.