1. Gymnema-75
™
Supports healthy
glucose metabolism 90 Vegi-Caps
Serving Size:
Gymnema Sylvestre
1 Capsule
500mg
(leaf extract)
• Helps deal with diabetes Total Gymnemic acids as per IP 375mg
Key Features:
• Lowers blood sugar levels Studied in type 1 diabetes
Suggested Use:
Take one to three capsules daily, or as
• Increases insulin levels directed by a qualified health care
practitioner.
• Helps reduce the risk of cardiovascular Source: Leaves.
disease Cautions:
• May reduce blood sugar levels.
• Use cautiously if hypoglycemic.
Healthy blood sugar levels • Can sometimes produce redness in
Gymnema-75 is an extract of the herb Gymnema sylvestre. This herb is the skin (rash).
used in Ayurvedic medicine to help with glucose metabolism. Gymnema • In rare instances, can irritate the
extracts have been tested scientifically and found to help with diabetes kidneys.
and its complications, such as cardiovascular disorders. Pregnancy / Nursing
No studies have been conducted. Best
Benefits for diabetics to avoid.
Clinical trials have found that Gymnema can lower blood glucose in both Main Indications:
insulin-dependent (type 1) and insulin-independent (type 2) diabetes. In As reported by literature:
non-insulin dependent diabetes, Gymnema reduced the requirements for • Antioxidant.
other medications. In diabetes mellitus patients, Gymnema increased the • Stimulation of liver regeneration.
body's levels of insulin and reduced the requirement for insulin. To date, • Anti-inflammatory.
• Choleretic.
no other substance has had this effect among insulin-requiring • Anti-hepatitis.
individuals. Gymnema was also found to help normalize lipid levels.
Complementary Products:
Gymnema is though to increase insulin sensitivity, and has been Ortho Glucose, R+Lipoic Acid
suggested to help regenerate or repair beta cells. Sustained, Advanced B Complex
Gymnema for glucose
Gymnema's effect on glucose metabolism offers important benefits for
anyone dealing with diabetes and/or the effects of high blood glucose
levels. It also offers protection against diabetic complications. AOR's
Gymnema-75 provides a high-potency, standardized extract of this
powerful herb.
Advanced
Orthomolecular Research www.aor.ca
To purchase9AOR products online, ,click here to visit T2E 6X8 Canada
AOR - 4101 19th Street NE Calgary, Alberta CURESELF.COM
Innovative Research
& Scientific Integrity

2. Gymnema-75
™
The Trouble With Glucose
A high dietary glycemic load, coupled with sedentary and stressful lifestyles, has contributed to the alarming
incidence of diabetes. Clinical complications include cardiovascular disease, peripheral vascular disease,
strokes, renal disease, atherosclerosis, and blindness. Numerous therapeutic approaches are available and
depend on individual response. Dietary restrictions and insulin administration, though effective, are not found
to correct the multiple tissue defects completely.
Oral hypoglycemic drugs such as sulfonylureas and biguanides are known to have serious side effects; hence,
the search for hypoglycemic agents which deal with the disease more completely and with minimum possible
undesirable effects still persists. In this context, the Ayurved herb Gymnema sylvestre has gained considerable
importance and generated much scientific and medical interest.
An Ayurvedic Herb
Gymnema sylvestre (GS), an herb belonging to the Asclepiadacea family, is a woody branched vine growing
in the wild forests of Central and South India. The plant has been used by the traditional medical practitioners
of India since Buddha's era. Early scientific studies of this herb observed that GS lowered blood glucose levels
in diabetic dogs but not in pancreactomized animals, suggesting that some residual pancreatic tissue is
needed for this herb to be effective. Further studies revealed that GS significantly lowered blood glucose levels
in both insulin-dependent and non-insulin-dependent diabetic rats.
Both Types of Diabetes
In human clinical trials, gymnema extracts were effective in patients with type 1 and type 2 diabetes (both
insulin-dependent and independent). In 22 type 2 diabetes patients, gymnema extract resulted in a significant
reduction in blood glucose, and in sugar-modified haemoglobin and plasma proteins. 5 of the 22 patients
were able to discontinue their standard medications and maintain healthy blood glucose levels with gymnema
alone.
Similar results were found in a study of 27 diabetes mellitus patients on insulin therapy. The gymnema, along
with its other effects, reduced the requirements for insulin and brought serum lipids to almost normal levels.
The gymnema extract appeared to enhance the body's own insulin, possibly by regenerating or repairing beta
cells which produce insulin.
Gymnema's Actions
More recent studies suggest that the GS may inhibit the release of Gastro-Intestinal Peptide (G.I.P which
.),
normally occurs following duodenal infusion of glucose. In addition to reducing the insulinotropic action of
gastro-intestinal hormones, GS is thought to increase peripheral insulin sensitivity. This might then result in
lowered insulin levels during a glucose tolerance test. The mechanism of action may be via the interaction
with the glucose receptor. This may explain the folklore claims of loss of sweet sensation following chewing
of GS leaves. In fact, GS is considered a carbohydrate metabolism modifier and has the following properties:
(1) Sensation of taste. The tongue sugar receptors are effectively blocked by GS, thereby inhibiting sensation
of sweetness.
(2) Glucose Control. Inhibition of uptake of glucose in the intestines by interacting with and blocking the
glucose receptor sites, thereby reducing the "spike" in glucose and insulin seen after a meal.
The active ingredients are thought to be saponin and glycoside derivatives. So far, eleven different types have
been isolated and identified as gymnemic acids. The chemical structure has been identified by nuclear
magnetic resonance and X-ray studies to be similar to glycuronides.
Advanced
Orthomolecular Research www.aor.ca
To purchase AOR productsNE , Calgary, AlbertatoT2E 6X8 Canada
AOR 9 - 4101 19th Street online, click here visit CURESELF.COM
Innovative Research
& Scientific Integrity