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Day 2 pm

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Day 2 pm

  1. 1. 呵护女性健康
  2. 2. Source: http://www.healthdata.org/singapore Women are living longer than Men 女性寿命比男性更长 女性 男性年龄 预计 年 预计 观察 女性 男性
  3. 3. https://www.hpb.gov.sg/docs/default-source/pdf/9-sep-2018---st-pg-a1---more-men-than-women-in-singapore-have-chronic-co.pdf?sfvrsn=7958c672_2 男性比女性的慢性病发生率更高
  4. 4. https://www.moh.gov.sg/resources-statistics/singapore-health-facts/principal-causes-of-death Principal Causes of Death 主要死亡原因 % of Total Death 占总死亡人数的百分比 1) Cardiovascular Diseases (including stroke) 心血管疾病 (包括中风) 31.3% 2) Cancer 癌症 29.1% 3) Pneumonia 肺炎 20.1% Principal Causes of death in 2017 in Singapore 2017年新加坡的主要死亡原因
  5. 5. • Heart Disease • Breast Cancer • Osteoporosis • Depression • Autoimmune Disease Women’sTop 5 Health Concerns 女性五大健康关注 https://www.webmd.com/women/features/5-top-female-health-concern#4 • 心脏病 • 乳癌 • 骨质疏松症 • 抑郁 • 自身免疫疾病
  6. 6. https://www.healthhub.sg/programmes/61/Screen_for_Life#tool-section Early Detection via Health Screening 通过健康检查尽早发现 根据您的年龄,您应该进行哪一类的健康检查?
  7. 7. https://www.healthhub.sg/programmes/61/Screen_for_Life#tool-section 提供各种辅助 ONLY PAY $0 - $5 FOR YOUR SCREENINGS 检费只需付$0新币 -$5新币 Nothing but the best deals for you and your loved ones 为您和爱人带来最好的优惠。 Singapore citizens pay $0-$5 per screening visit . Other subsidised rates apply for PRs. 新加坡公民只需付$0新币 - $5新币检查。永久公民将有其他补助费。 建国一代 CHAS蓝卡和橙卡 合格新加坡公民
  8. 8. https://www.healthhub.sg/programmes/61/Screen_for_Life#tool-section 50岁以上 40岁以上 25岁以上 结直肠癌 乳腺癌 慢性病 宫颈癌 宫颈癌 慢性病 宫颈癌 提供以下健康检查补助: 定期检查是健康生活的一部分,因此尽早检查并且保持健康。 以下推荐不同年龄段的检查:
  9. 9. https://www.healthhub.sg/programmes/61/Screen_for_Life#tool-section 成年人 18岁以上 孩子 17岁以下 我的年龄段 18-24岁 显示结果 慢性病 高血压 肥胖 糖尿病 免疫接种 人乳头瘤病毒 (女性)
  10. 10. Women and Healthy Lifestyle 女性及健康的生活方式 Balanced eating habits 均衡的饮食习惯 Regular physical activity 规律的体育活动 Stress management for internal balance 压力管理维持内在平衡 Sleep for proper mind/body functioning 充足的睡眠让头脑/身体正常运转 Proper nutrition 良好的营养
  11. 11. Women and Balance 女性与平衡 Maintaining a healthy lifestyle when women are on the run between work, family and friends means often supporting their health can get pushed to the back burner. Reaching balance requires a mixture of vitamins, antioxidants and powerful minerals in the right combination. 当女性奔波于工作、家庭和朋友 之间,维持健康的生活方式常常 意味着她们把自己的健康放在次 要的位置上。 达到平衡状态需要一种配比恰当 的维生素、抗氧化物及强效矿物 质混合补充品。
  12. 12. Is there a Supplement for: • foggy brain • can’t sleep • wake up sluggish Still want to: • look refreshed • helps my heart • helps my bones • helps my brain • And is of course SAFE? BUT … Women and Balance 女性与平衡 有没有一种营养补充品可以帮助解决: • 脑雾 • 失眠 • 醒来没精神 但... 仍希望能: • 看起来精神饱满 • 对心脏有益 • 对骨骼有益 • 对大脑有益 • 而且,当然还要是安全的?
  13. 13. More than a multivitamin, Isotonix Essentials Women’s Health benefits women by providing a foundation of nutrients that deliver vibrancy. 。 WOMEN’S HEALTH 女性保健配方粉末 COMPLEXION • BALANCE • VITALITY 气色 • 平衡 • 活力 女性保健配方粉末不仅仅是一款综合维生素, 它透过建立良好的营养基础,为女性增加活力, 从而使女性受益匪浅。
  14. 14. B-Vitamins 维生素B群 Essential B vitamins to support: • Healthy red blood cell formation • Metabolism of fats, carbohydrates and protein for energy level • Cardiovascular health • Strong hair & nails 必需的B族维生素能够支援: • 健康的血红细胞形成 • 脂肪、碳水化合物和蛋白质的代谢, 以提高能量水平 • 心血管健康 • 强韧的头发与坚固的指甲
  15. 15. Magnesium, Calcium & D3 镁、钙和D3 • Support strong bone and teeth • Support normal functioning of muscle and nervous tissue • Promote the normal regulation of the heart and blood pressure • 支援强健的骨骼和牙齿 • 支援肌肉与神经组织的正常运作 • 促进心脏与血压的正常调节
  16. 16. Antioxidants 抗氧化物 Beta-Carotene Vitamin C Vitamin E Olive Fruit Extract Pine Bark Extract (Pycnogenol®) Bilberry Extract Grape Seed Extract Grape Skin Extract Citrus Flavonoid B-胡萝卜素 维生素C 维生素E 橄榄萃取物 松树皮萃取物(碧容健) 山桑子萃取物 葡萄籽萃取物 葡萄皮萃取物 柑橘类黄铜
  17. 17. Antioxidants protect the body from free radicals and help support: • A healthy immune system • Cardiovascular health • Skin health • Vision health • Blood circulation • Normal cell health Antioxidants 抗氧化物 抗氧化物保护身体免受 自由基影响,并且帮助支援: • 一个健康的免疫系统 • 心血管健康 • 皮肤健康 • 视力健康 • 血液循环 • 正常的细胞健康
  18. 18. Trace Minerals 微量元素 • Iron (SunActive® Fe) • Zinc • Copper • Iodine • Molybdenum In small amounts but essential for good health. • 铁(SunActive® Fe) • 锌 • 铜 • 碘 • 钼 虽然需要的量很少,但是对 维持良好健康非常重要。 SunActive is a trademarked ingredient of Taiyo International Taiyo International © 2017
  19. 19. Iron (SunActive® Fe) 铁(SunActive® Fe) • SunActive® Fe provides a nonirritating iron supplementation with superior properties and bioavailability. • Unlike many other iron sources found in supplementation SunActive® is stable against pH and oxidation. • In addition, SunActive® Fe is mild on the gastrointestinal system. • SunActive® Fe 提供无刺激性的铁补充 品,具有优良特性及高度的生物可利 用性。 • 与其他营养保健品里的铁来源不同, SunActive® Fe在pH环境和氧化作用下 仍较为稳定。 • 而且, SunActive® Fe性质温和, 不伤肠胃系统。 SunActive is a trademarked ingredient of Taiyo International Taiyo International © 2017
  20. 20. Primary Benefits of WOMEN’S HEALTH 女性保健配方粉末 主要好处 • Supports a healthy complexion • Helps support healthy bones, teeth and joints • Supports healthy muscle and nerve function • Supports cardiovascular health • 支援健康好气色 • 有助于支援健康的 骨骼、牙齿和关节 • 支援健康的肌肉与 神经功能 • 支援心血管健康
  21. 21. • Provides a foundation of nutrients that meets a diversity of female needs • Contains no gluten, wheat, soy, yeast, artificial flavour, salt, preservatives or milk • Individually packaged Primary Benefits of WOMEN’S HEALTH 女性保健配方粉末 主要好处 • 提供可满足女性多 样化需求的营养素 基础 • 不含麸质、小麦、 黄豆、酵母、人工 香精、盐、防腐剂 或奶 • 单独包装
  22. 22. Women’s Needs Change 女性的需求不断改变
  23. 23. • During the menstrual cycle, estrogen produces an environment suitable for the fertilisation, implantation, and nutrition of an early embryo. • Progesterone, hormone secreted by the female reproductive system that functions mainly to regulate the condition of the inner lining (endometrium) of the uterus. Effects of Hormonal Imbalance 荷尔蒙失调的影响 • 在月经期间,雌激素能提供一个适 宜的环境,以受孕、着床并为胚胎 的早期发育提供所需营养。 • 黄体酮,一种由女性生殖系统所分 泌的荷尔蒙,主要功能是帮助调节 子宫内粘膜(子宫内膜)的形态。
  24. 24. https://www.health.harvard.edu/womens-health/menopause-and-perimenopause- Perimenopause – begins several years BEFORE menopause in which the female hormone, estrogen, rises and falls unevenly. Postmenopause – these are the years AFTER menopause. Due to low level of estrogen, postmenopausal women are at increased risk for some health conditions, such as osteoporosis and heart disease. Effects of Hormonal Imbalance 荷尔蒙失调的影响 更年期前期 - 更年期的前 几年开始,期间女性荷尔蒙 和雌激素水平上下波动。 绝经后期 - 更年期之后的 数年。 因为雌激素的水平较低,更 年期后的女性某些健康问题 的风险增加,比如骨质疏松 症和心脏病。
  25. 25. • Swollen or tender breasts • Feeling tired • Trouble sleeping • Upset stomach, bloating, constipation, or diarrhea • Cramps • Headache or backache • Appetite changes or food cravings • Joint or muscle pain • Trouble with concentration or memory • Tension, irritability, mood swings • Anxiety or depression PMS: Premenstrual syndrome 经前综合症 Premenstrual Symptoms (PMS) – physical & emotional 经前症候群(PMS) — 身体&情绪 • 乳房肿胀或压痛 • 感觉疲惫 • 睡眠问题 • 胃部不适、腹胀、便秘或腹泻 • 腹痛 • 头痛或背痛 • 食欲改变或渴望食物 • 关节或肌肉疼痛 • 注意力或记忆力问题 • 紧张、易怒、情绪波动 • 焦虑或抑郁
  26. 26. • Symptoms vary from woman to woman • 85% of menstruating women have at least one symptom • PMS occurs more often in women who: – Are between their late 20s and early 40s – Have high level of stress – Have a family history of depression – Have a past medical history of either postpartum depression or a mood disorder PMS: Premenstrual syndrome 经前综合症 How Common is PMS? 经前症候群有多普遍? • 每个女性的症状都不同 • 85%的月经期女性至少有一种症状 • 患经前症候群的女性通常: - 年龄介于20岁后期到40岁初 - 压力大 - 有家族抑郁病史 - 曾有产后抑郁症或情绪障碍的病史
  27. 27. “The MenopausalYears” is a natural stage of life Women will describe a number of different symptoms, at varied times in their reproductive years While it may be normal, it certainly doesn’t feel normal Premenopausal & Menopause 更年期前期与更年期 “更年期”是一个自然的生命 阶段 在生育年龄的不同时期,女 性会描述许多不同的症状 虽然这可能是正常的, 但感觉上肯定不正常
  28. 28. Changing hormone levels during menopause can cause symptoms such as: • Hot flashes • Difficulty sleeping • Mood changes • Becoming forgetful or having trouble focusing • Depression and anxiety • Urinary problems • Increased vaginal dryness and sensitivity • Sex life changes https://www.womenshealth.gov/ Menopause Symptoms 更年期症状 更年期期间荷尔蒙水平的变化可能 会引起如下症状: • 潮热 • 睡眠困难 • 情绪多变 • 健忘或者难以集中注意力 • 抑郁和焦虑 • 泌尿系统问题 • 阴道过于干燥和敏感 • 性生活发生变化
  29. 29. Women and Balance 女性与平衡 Is there a Supplement that may • Help to stabilise mood? • Help to counteract mild effects of Premenstrual Syndrome (PMS)? • Helps reduce the discomfort of mild symptoms associated with menopause? 有没有一种营养保健品可以 有助稳定情绪? • 有助稳定情绪? • 有助减轻经前症候群(PMS)的 些微症状? • 舒缓更年期的轻度不适症状?
  30. 30. Prime Feminene™ Ingredients Prime Feminene™女性呵护配方成分  B-Vitamins  Dong Quai  Soy Isoflavones  WildYam  Black Cohosh  Chasteberry Fruit Extract  Horsetail Extract  Red Clover Extract  Passion Flower  Valerian Root  Red Sage Extract  Tribulus terrestris  维生素B群  当归  大豆异黄酮  野山药  黑升麻  圣洁莓萃取物  木贼萃取物  红花苜蓿萃取物  西番莲  缬草根  红色鼠尾草(丹参)萃取物  蒺藜
  31. 31. Benefits of Prime Feminene™ Prime Feminene™女性呵护配方成分的益处  B-Vitamins: Energy / Mood / Stress  Dong Quai: Mild Cramps / Hot Flashes  Soy Isoflavones: Hot Flashes / Phytoestrogens / Bone Health  WildYam: Cramps / Hot Flashes / Fatigue  Black Cohosh: Hot Flashes /Vaginal Dryness  Chasteberry Extract: Hot Flashes  维生素B群:能量/情绪/压力  当归:轻微腹痛/潮热  大豆异黄酮:潮热/植物雌激素/骨骼健康  野山药:腹痛/潮热/疲乏  黑升麻:潮热/阴道干燥  圣洁莓萃取物:潮热
  32. 32.  Horsetail Extract: UrinaryTract / Mild symptoms of PMS  Red Clover Extract: Hot Flashes  Passion Flower: Sleep / Restlessness  Valerian Root: Stress Reduction / Mood / Sleep  Red Sage Extract: Hot Flashes / Cramps  TribulusTerrestris: Hormonal Balance  木贼萃取物:泌尿系统/经前症候群  红花苜蓿萃取物:潮热  西番莲:睡眠/烦躁不安  缬草根:减低压力/情绪/睡眠  红色鼠尾草(丹参)萃取物:潮热/腹痛  蒺藜:荷尔蒙失调 Benefits of Prime Feminene™ Prime Feminene™女性呵护配方成分的益处
  33. 33. • May help to stabilise mood • May help to reduce the discomfort of mild symptoms associated with menopause • Helps to counteract mild effects of Premenstrual syndrome (PMS) Benefits of Prime Feminene™ Prime Feminene™女性呵护配方的益处 • 有助稳定情绪 • 有助舒缓更年期的轻度 不适症状 • 有助减轻经前症候群的 轻微影响
  34. 34. How is Prime Feminene™ different from other similar supplement products on the market? Many women’s health product supplements focus on botanicals or herbs for a small percentage of female concerns and are limited to certain ages More than other products on the market, Prime Feminene™ meets a diversity of female needs through all her years Prime Feminene™ Prime Feminene™女性呵护配方的益处 Prime Feminene™女性呵护配方有何独特之 处? 许多女性保健品补充剂针对一小部分女性 关注的问题,着重于植物或草药,而且仅 限于特定年龄 与市场上的其他产品相比,Prime Feminene™女性呵护配方满足了女性多年 来的各种需求
  35. 35. So while you’re managing life like a champ, let Women’s Health & Prime Feminene™ be there to back you up! 在您成为人生赢家的道路上,请让Isotonix Essentials™女性保健配方粉末及 Prime Feminene™女性呵护配方祝您一臂之力!
  36. 36. 呵护女性健康
  37. 37. HEALTHCARE FOR HIM 照顾男士健康 Photo by Peter Hershey on Unsplash
  38. 38. Within a 100 years, life expectancy rose from 40 to 80 years. Likelihood of reaching 65 increased 3-fold, from 30% to 90%. 过去100年间,人类的预期寿命已从40岁 上升至80岁。 活到65岁的可能性从30%增加到90%, 提升了3倍。 https://ourworldindata.org/life-expectancy
  39. 39. Male Life Expectancy 男性预期寿命 • Average life expectancy for men in Singapore is 84.7 years (compared with 87.9 for women) • 1:4 Men Has Heart Disease and May Not Know It (Am. Heart Assoc-2013) • Indications are things like: – Fatigue with no cause otherwise – Poor erectile function- the penis is a great barometer for severity of heart disease – Family history – Being overweight or obese Source: Life Expectancy, Department of Statistics Singapore Am. Heart Assoc-2013 • 新加坡男性的平均预期寿命为84.7岁 (女性为87.9岁) • 4位男性中就有1位罹患心脏病,可能还 不自知 (Am. Heart Assoc-2013) • 征兆例如: – 无缘无故的疲劳 – 勃起功能不良 — 阳具是心脏病严 重程度的晴雨表 – 家族病史 – 过重或肥胖
  40. 40. Men are 24 percent less likely than women to have visited a doctor within the past year and 22 percent more likely to have neglected their cholesterol tests. 在过去一年里,男性的看病人数 比女性约低24%,而忽略胆固醇 测试的可能性高出22%。 https://archive.ahrq.gov/patients-consumers/patient-involvement/healthy-men/index.html
  41. 41. National Population Health Survey Singapore, 2017 全国人口健康调查 新加坡,2017年 Conditions 健康状况 Male 男性 Female 女性 Overweight 过重 43.4% 29.4% Hyperlipidemia 高脂血症 40.9% 26.6% Hypertension 高血压 23.8% 19.6% Daily Smoking 每天吸烟 21.1% 3.4% Diabetes melitus 糖尿病 10.3% 7.1%
  42. 42. Beside colo-rectum and lung cancer, prostate cancer is the 3rd common cancers affecting Men 除结直肠癌和肺癌外, 前列腺癌是影响男性的 第三大常见癌症
  43. 43. 3M Healthcare Concepts 3M保健概念 Make food your medicine Make inactivity your enemy Make supplements your ally 把食物当作您的药 视不活动为您的敌人 将营养保健品当作您的同盟
  44. 44. • Changing your lifestyle and dietary habits should also be looked at as the first point in your overall health regime • Consuming a wide variety of fruits and vegetables has been shown to be moderately good in reducing prostate health risk • 改变您的生活方式和饮食习惯也应该被视为 您整体健康制度的第一点 • 食用多种水果和蔬菜已被证明对降低前列腺 健康风险有一定的好处 Make Food Your Medicine 把食物当作您的药
  45. 45. • Exercise alone is not enough. Working out three times a week is not enough. Being active throughout the day is what keeps you healthy - Tom Rath, author of Eat, Move, Sleep • 单靠运动是不够的。每周运动三次是不够 的。全天都活动才能让您保持健康 - Tom Rath, 《吃、动、睡》的作者 Make Inactivity Your Enemy 视不活动为您的敌人
  46. 46. Make Supplements Your Ally 将营养保健品当作您的同盟
  47. 47. What is Plant Sterol? 什么是植物固醇? • Chemical structure found in plant which is very similar to animal cholesterol • Fruits, Vegetables, Nuts, Seeds, Legumes contain small amount of Plant Sterol • More than 40 clinical trials assessed the efficacy of phytosterols in patients with hyperlipidemia • The American heart association (AHA) recommends eating 1.6 to 3 grams of plant sterol per day to help reduce LDL cholesterol by 10 to 11 percent • Helps to slow down the rate of the prostatic gland hypertrophy http://www.medscape.com/viewarticle/725629 Am J Health Syst Pharm. 2010;67(14):1165-1173 • 在植物中发现的化学结构与动物胆固 醇非常相似 • 水果、蔬菜、坚果、种子、豆类都含 有少量的植物固醇 • 40多项临床试验评估了植物固醇对高 脂血症患者的疗效 • 美国心脏协会(AHA)建议每天摄取1.6 至3克植物固醇,以帮助将LDL胆固醇 降低10%至11% • 有助于减缓前列腺肥大的速度
  48. 48. Stinging Nettle Root Extract (Urtica dioica) 刺荨麻根萃取物 (异株荨麻) • Works in combination with other ingredients to support urinary health • Tissue growth • DHT levels • Other traditional uses • 结合其他成分一起使用,以支援泌尿健康 • 组织生长 • 双氢睾酮(DHT)水平 • 其他传统用途
  49. 49. Pumpkin Seed Extract 南瓜籽萃取物 • Pumpkin seeds contain plant sterols • Inhibitory effect on the conversion of testosterone to DHT and promote hypertrophy of the prostate gland • Pumpkin seed oil can effectively improve the symptoms of prostate hypertrophy • 南瓜籽含有植物固醇 • 对于睪酮转化为双氢睾酮从而促 进前列腺肥大有抑制的效果 • 南瓜籽油能有效改善前列腺肥大 的症状 Shirvan MK, et al. J Pak Med Assoc. 2014 Jun;64(6):683-5. Coulson S, et al. Complement Ther Med. 2013 Jun;21(3):172-9.
  50. 50. Genistein 金雀异黄酮 • One of the most physiological functions of isoflavones is found in soybeans • Patented genoa isoflavones geniVida™ • In the 90s, studies have confirmed that it can delay prostate enlargement Geller J, et al. Prostate. 1998 Feb 1;34(2):75-9. • Genistein can inhibit the detachment, invasion and metastasis of prostate cancer cells M Pavese, et al. Am J Clin Nutr. 2014 Jul; 100(1): 431S–436S. • 是存在于大豆中、最具生理功能的异 黄酮之一 • 获得专利的金雀异黄酮geniVida™ • 在90年代,研究已经证实它可以延缓 前列腺肿大 Geller J, et al. Prostate. 1998 Feb 1;34(2):75-9. • 金雀异黄酮能抑制前列腺癌细胞的剥 离、侵入与转移 M Pavese, et al. Am J Clin Nutr. 2014 Jul; 100(1): 431S–436S.
  51. 51. Additional benefits of Genistein 金雀异黄酮的其他益处 • Reduce the risk of developing diabetes and cardiovascular disease in patients with metabolic syndrome Squadrito F, et al. J Clin Endocrinol Metab. 2013 Aug;98(8):3366-74. Behloul N, Wu G. Eur J Pharmacol. 2013 Jan 5;698(1-3):31-8. • Improving post menopausal women's hot flushes, quality of life and depression symptoms Atteritano M, et al. Osteoporos Int. 2014 Mar;25(3):1123-9. Evans M, et al. Maturitas. 2011 Feb;68(2):189-96. • 降低代谢综合症患者罹患糖尿病和心 血管疾病的风险 Squadrito F, et al. J Clin Endocrinol Metab. 2013 Aug;98(8):3366-74. Behloul N, Wu G. Eur J Pharmacol. 2013 Jan 5;698(1-3):31-8. • 改善绝经后妇女的潮热、抑郁症状, 提高生活品质 Atteritano M, et al. Osteoporos Int. 2014 Mar;25(3):1123-9. Evans M, et al. Maturitas. 2011 Feb;68(2):189-96.
  52. 52. Grape Seed Extract 葡萄籽萃取物 • Rich in Proanthocyanidins • Strong antioxidant and anti-inflammation • 富含原花色素 • 强大的抗氧化及抗炎 效果
  53. 53. Specific supplementation may also be considered. Prime MPC™ is a specially formulated supplement that may offer benefits for male urinary and prostate health 您还可以考虑使用某些相关的营养补 充品。 Prime MPC™ 前列健保健配方是一种特 殊配方的补充剂,可以为男性泌尿和前 列腺健康带来益处 Prime MPC™ Prime MPC™前列健保健配方
  54. 54. Bigger is not better when it comes to your prostate! 前列腺并非越大越好! • Prostate is about the size of a walnut. • Sits at the base of the bladder. • Wraps around the urethra (the tube that urine passes through). • Benign Prostatic Hypertrophy (BHP) is prostate enlargement with ageing. • 前列腺约核桃大小。 • 位于膀胱底部。 • 环绕尿道(尿液通过的管道)。 • 良性前列腺增生(BPH)是随着 年龄增长而引起的前列腺增生。
  55. 55. Risk Factors 风险因素 •Age •Family History •Obesity •Environmental Factors •年龄 •家族病史 •肥胖 •环境因素
  56. 56. http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/endocrinology/male-hypogonadism/ 睾酮及其代谢产物对男性的影响 睾酮 双氢睾酮 雌二醇 面部和体毛 粉刺 头皮脱发 前列腺增长 肌肉质量 骨骼生长 精子 性功能 骨形成 乳房组织
  57. 57. 5- α Reductase DHT Dihydrotestosterone DHT双氢睾酮 Testosterone 睾酮 Male Hormone 男性荷尔蒙 好 不良
  58. 58. Comprising of: • Plant Sterols • Stinging nettle root extract • Pumpkin Seed Extract • Genistein • Grape Seed Extract • Zinc 该产品的成分有: • 植物固醇 • 刺荨麻根萃取物 • 南瓜籽萃取物 • 金雀异黄酮 • 葡萄籽萃取物 • 锌 Prime MPC™ Prime MPC™前列健保健配方
  59. 59. MPC Ingredients MPC成分 Pumpkin Seeds Extract 南瓜籽萃取物 Plant Sterols 植物固醇 Genistein (GeniVida™) 金雀异黄酮 Grape Seeds Extracts 葡萄籽萃取物 Zinc 锌 Stinging nettle root extract 刺荨麻根萃取物
  60. 60. HEALTHCARE FOR HIM 照顾男士健康
  61. 61. Market Singapore® | SG.SHOP.COM Product Symposium 2019 美安新加坡™ | SG.SHOP.COM 2019产品专题会 COMPLETE CARE FOR YOUR LITTLE ONES 给宝贝完善的照顾
  62. 62. “Malnutrition in mothers can lead to developmental problems in their children” “母体营养不良会导致孩子们的发育问题”
  63. 63. From birth or prenatal? 从出生之日起还是在怀孕时? • Studies have found that pregnant women who are consume the recommended intake of fish oil generally demonstrate a beneficial effect on neurodevelopmental outcomes of offspring • 研究发现,孕妇摄入建议量的 鱼油,通常有益于后代的神经 发育。 Source: Omega-3 fatty acids and pregnancy, Coletta, J.M., Bell, R.D., & Roman, A.S. Reviews in Obstetrics & Gynecology, Vol 3(4), fall 2010. PMC 3046737
  64. 64. Human milk from donors boost baby’s immune system 捐赠的母乳可以增强宝宝的免疫系统
  65. 65. Our children and youth are the future of Singapore. Good health is the best foundation for the overall development of our children and youth. Yet there are many challenges faced by parents these days. 我们的儿童和青年是新加 坡的未来。 良好的健康为我们的儿童 和青少年全面发展奠定了 最佳基础。 然而,当今的父母们却面 临着许多挑战。
  66. 66. “We work hard to keep our homes sparkling clean, but it puzzles us as to why our young children still fall sick so often. In May 8-14, 2016, weekly cases of hand, foot and mouth disease hit a four-year high. Singapore has constantly been fighting such harmful diseases, and the regular resurgences in these illnesses shows that they are here to stay. Other problematic occurrences like the influenza have similarly plagued Singapore. Weekly status updates from the Ministry of Health reveal that individuals going to polyclinics with Acute Respiratory Infections have actually been higher in 2017 than in the same time frame last year.” Children attending preschool are exposed to germs 幼儿园的学童容易接触到细菌 “我们努力让自己的家庭保持干 净,但令我们困惑的是,为什么 孩子们仍会然经常生病。 2016年5月8至14日,手足口病的 每周发病率达到四年来的新高。 新加坡一直在与这些有害疾病作 战,而这些疾病的定期复发则表 示它们就在我们身边。 其他疾病例如流感,其发病率也 同样困扰着新加坡。卫生部每周 疫情通告披露,2017年到综合诊 所就诊的急性呼吸道感染病人实 际上高于去年同期人数。” 为什么您的孩子经常生病
  67. 67. Children attending preschool are exposed to germs 幼儿园的学童容易接触到细菌 今年每周手足口病病例数创历史新高,7月29日至8月4日期间共有1249例病 例
  68. 68. Pasir Ris-Punggol GRC MP Teo Ser Luck told The Straits Times yesterday: "I am very concerned about this issue, especially since this is not the first food- poisoning case to occur this year. A thorough investigation must be conducted, and a good explanation must be given to all parents." What about food hygiene? 食品卫生又如何呢? 白沙 – 榜鹅集选区 (Pasir Ris-Punggol)国会 议员张思乐(Teo Ser Luck)昨天告诉《海峡时 报》:“我非常担心这 个问题,尤其是这已经 不是今年发生的第一起 食物中毒事件。必须进 行彻底调查,并向所有 家长作出合理的解释。”
  69. 69. What happens when you have a child who is a picky eater? 如果您有个挑食的孩子会怎样? Researchers in the Netherlands have started to address this concept by analyzing eating habits in >3,500 children from a population-based cohort. The children were assessed for picky eating at ages 1.5, 3 and 6 years by maternal report and for problem behaviours at age 7 years using the Teacher’s Report Form. The majority of children (51.4%) were not picky eaters, 31.9% were remitting picky eaters and 5.5% were persistent picky eaters. Data analysis found that persistent picky eating could predict pervasive developmental disorders at age 7 years, but was not associated with behavioural (attention hyperactivity and oppositional defiant problems) or emotional problems (anxiety and affective problems). Source: Cardona Cano, S., Hoek, H.W., van Hoeken, D., de Barse, L.M., Jaddoe, V.W.V., Verhulst, F.C. & Tiemeier, H. (2016), Behavioral outcomes of picking eating in childhood: a prospective study in the general population. J Child Psychol Psychiatr. 57: 1239-1246. doi:10.1111/jcpp.12530 荷兰的研究人员已经开始应对 这个问题,他们通过一项基于 人口的追踪研究,对3,500多名 儿童的饮食习惯进行分析。这 些孩子们分别在1岁半、3岁和6 岁时通过母亲一方的报告对其 挑食状况进行评估,在7岁时则 使用老师的报告表格对其问题 行为进行评估。大多数儿童 (51.4%)不挑食,31.9%的儿童 挑食行为会缓解,5.5%的儿童 挑食行为则是持久性的。数据 分析发现,持久性挑食行为在7 岁时即可预见到其广泛的发育 障碍,但这与行为(注意力不 足过动症和对立性反抗问题) 或情绪方面(焦虑和情感问题) 的问题无关。 当餐桌变成战场
  70. 70. Physical Growth 身体成长 Cognition 认知 Emotional 情绪 Crucial in Foundational Developments 基础发育的关键 Height Weight Organ Size Skeletal Mental Learning Ability Perception Senses Decision Making Personality Self Control Socialization 身高 体重 器官大小 骨骼 心理 学习 能力 知觉 感官 决策 个性 自我控制 社会化
  71. 71. Low iron levels affect cognitive function A Deficiency increases risk of lead toxicity Nutrition Concern 营养问题 Enough Iron 足够的铁 铁含量偏低影响 认知功能 缺铁会增加铅中 毒的风险
  72. 72. Poor Dietary Practice 不良饮食 习惯 Nutrition Concern 营养问题 Overweight and Obesity 过重与肥胖 Inadequate Bone Mass 骨量不足 Slow Growth Rate 缓慢成长 速度 Caloric Imbalance 热量不均衡 Mental Physical Function 心理生理功能 Low Micronutrients Reserve 偏低的微量 营养素储备 Delayed Sexual Maturation性 成熟延迟
  73. 73. Nutritional Deficiencies 营养不足 No. 1 Reason for Poor Health 头号原因 健康不良 Iron Deficiencies 铁不足 Dental Caries 蛀牙 Low Resistance To Infections 抵抗力弱 对抗感染 Increased Risks In Adulthood of Chronic Diseases 风险增加 成年后慢性疾病 Nutrition Concern 营养问题 Overweight and Obesity 过重与肥胖
  74. 74. Increased Risks: Obesity in Adulthood Heart Disease Osteoporosis Some Cancers Nutrition Concern 营养问题 Overweight and Obesity 过重与肥胖 风险增高: 成年后肥胖 心脏病 骨质疏松症 某些癌症
  75. 75. Focus On Nutrient Density Not Portion Control Not Calorie Control Nutrition Suggestion 营养的建议 Overweight and Obesity 过重与肥胖 关注营养素密度 而非食量控制 也非热量控制
  76. 76. One of Dr Andrew Sng's patients weighed 80kg and was diagnosed with high blood pressure - and he was just eight years old. The primary school pupil is among a growing number of children diagnosed with the condition, which is more commonly associated with middle-aged adults. Andrew Sng医师有一位患者,体重 达到80公斤,被诊断出患有高血 压 — 而当时他只有8岁。 这种通常多发生在中年人的疾病, 越来越多地从小学生身上诊断出来。 高血压儿童日益严重的问题
  77. 77. 在美国10至18岁的年轻人中, 2型糖尿病的发病率以每年 4.8%的速度增长。 刘医师说,年轻人肥胖盛行率 的迅速上升被认为是2型糖尿 病早发的根本原因。 他还说到,这需要大家一起努 力,提倡健康的生活方式,增 加儿童和青少年的体育活动, 以控制他们的体重,降低在成 年早期患糖尿病的风险。 In the US youth population aged 10 to 18, the incidence of Type 2 diabetes increases at a rate of 4.8 per cent each year. Dr Liu said the rapidly rising prevalence of obesity in the young is believed to be the root cause of early onset Type 2 diabetes. He added that this calls for a concerted effort to promote healthy lifestyles, and increasing physical activities for children and adolescents to control their body weight and reduce the risk of developing diabetes in early adulthood. 研究:年轻糖尿病患者患慢性肾病的风险更高
  78. 78. New data analysis found that people can experience multiple forms of malnutrition at the same time. More than eight million children around the world are both stunted and overweight. Dr Fan Shenggen, director- general of Ifpri (International Food Policy Research Institute), said many people still do not understand what it takes to eat right and the longer-term consequences of poor nutrition. "A country getting richer will help, but it's not sufficient," he told The Straits Times in Bangkok. "Many rich countries still have child stunting." 新的数据分析发现,人们可 以同时经历多种形式的营养 不良。全世界有800多万名儿 童发育不良和过重问题并存。 国际食物政策研究所 (International Food Policy Research Institute, IFPRI)所长 樊胜根(Fan Shenggen)博士说, 许多人仍然不明了正确的饮 食之道,以及营养不良的长 期后果。他在曼谷接受《海 峡时报》采访时表示:“国 家日渐富有会对这有所改善, 但还是不够的。” “许多富 裕的国家仍然有儿童发育不 良的问题。” 报道:东南亚正在努力应对发育不良的孩子,贫血症
  79. 79. Carbohydrates • 50% calories from carbohydrates Fibre • Age 1 -3 : 19 grams a day • Age 4 – 8 : 25 grams a day Fats • Age 1 – 3 : 30-40% of calories from fat • Age 4 – 8 : 25-35% of calories from fat Protein RDA • Age 1- 3 : 13 grams a day • Age 4 – 8 : 19 grams a day Adequate Diet Provision 适当的膳食规范 碳水化合物 • 50%的卡路里来自碳水化合物 纤维 • 1 – 3岁:每天19克 • 4 – 8岁:每天25克 脂肪 • 1 – 3岁:30-40%的卡路里 来自脂肪 • 4 – 8岁:25-35%的卡路里 来自脂肪 蛋白质建议摄取量 • 1 – 3岁:每天13克 • 4 – 8岁:每天19克
  80. 80. • Essential Fatty Acids – Brain matter, nervous system, hormones • Antioxidants – Diseases that began at childhood, metabolic syndrome, cellular damage • Vitamin A – Immune function (T-cell production), vision, reproductive, cellular communication • Calcium (600 – 800 mg daily) – Building blocks of skeletal system, muscle contraction, nerves communication Nutrient Requirements 营养需求 • 必需脂肪酸 – 大脑物质、神经系统、荷尔蒙 • 抗氧化物 – 童年开始的疾病、代谢综合症、细 胞损伤 • 维生素A – 免疫功能(T淋巴細胞生产)、视 力、生殖、细胞通讯 • 钙(每日600 – 800毫克) – 构建骨骼系统、肌肉收缩、神经交 流
  81. 81. • Magnesium (100 – 250mg daily) – Childhood stress & depression, hormonal fluctuations • Iron – Prevent anemia & developmental delay (behavioral, cognitive) • Zinc – Learning disabilities, attention span, frequent colds & flu Nutrient Requirements 营养需求 • 镁(每日100 - 250毫克) – 儿童压力和抑郁、荷尔蒙波 动 • 铁 – 预防贫血与发育迟缓(行为、 认知) • 锌 – 学习障碍、注意力广度、频 发的感冒及流感
  82. 82. • Digestive Enzymes • Essential Omega 3, 6, 9 • Probiotics • Multivitamin • OPC-3 Nutritional Support 营养支柱 • 消化酵素 • Omega鱼油 3、6、9 • 益生菌 • 综合维生素 • OPC-3
  83. 83. Pycnogenol® in Children’s Health 碧容健对儿童健康之帮助 • Pycnogenol helps to improve children who lack of attention and hyperactive related symptoms (Trebaticka et al., Eur Child Adolesc Psychiatry 15: 329-335, 2006) • Pycnogenol improves the asthma related symptoms (Belcaro et al., Panminerva Med 53(3 Suppl 1): 57-64, 2011.) • Pycnogenol promotes the immune response to the virus (Cheshier et al., Pharmacol Letters 58: 87-96, 1996) • Pycnogenol shortens the flu course (Belcaro, G., et al. Panminerva Med. 2014 Dec;56(4):301-8.) • 碧容健有助于改善儿童的 注意力不足及过动相关症 状(Trebaticka et al., Eur Child Adolesc Psychiatry 15: 329-335, 2006) • 碧容健改善哮喘相关症状(Belcaro et al., Panminerva Med 53(3 Suppl 1): 57-64, 2011.) • 碧容健促进对病毒的免疫 反应(Cheshier et al., Pharmacol Letters 58: 87-96, 1996) • 碧容健缩短感冒病程(Belcaro, G., et al. Panminerva Med. 2014 Dec;56(4):301-8.)
  84. 84. Moms, dads, and pediatricians understand how difficult it is to ensure their children get the nutrients they need – especially all-important antioxidants. Give Your Children The Essentials! 给孩子最好的! 父母与儿科医师都了解,要 确保孩子得到所需的营养是 多么不容易 — 特别是摄取 重要的抗氧化物尤其困难。 什么时候 担心
  85. 85. Why do children need antioxidants? 为什么儿童需要抗氧化能力? OPCs provide exceptional nutritional benefits It’s difficult for children to get complete antioxidant protection from their typical diet, especially if they are picky eaters Studies shown OPCs to be up to 20 times more powerful than vitamin C in neutralising free radicals OPCs 原花色素 Up to 20 times more powerful 高达20倍 的强效作用 > 维生素 C 原花色素(OPC)提供 卓越的营养功效 研究显示,原花色素中 和自由基的作用比维生 素C可强大多达20倍 孩子无法从日常饮 食中获得足够且全 面的抗氧化防护, 尤其是挑食的孩子。
  86. 86. Make taking supplementation become interesting 让营养补充品变得有趣 DNA Miracles OPC-3® Chews DNA Miracles OPC-3®软糖 • Contains high quality antioxidant ingredients - Pycnogenol - Grape seed extract - Blueberry extract - Citrus bioflavonoids extract - Red wine extract • Delicious • Children are highly receptive • 含优质抗氧化成分 - 碧容健 - 葡萄籽萃取物 - 蓝莓萃取物 - 柑橘生物类黄酮萃取物 - 红酒萃取物 • 美味 • 孩子们的接受度很高
  87. 87. WHY OPC-3® CHEWS ARE GREAT FOR MY CHILDREN? 为什么OPC-3®软糖对我的孩子有好处? Supports healthy blood vessel function and blood flow 支援健康血管功 能与血流量 Ideal for everyone who has difficulty swallowing tablets 适合无法吞 咽药粒者 Children get the power of Pycnogenol® in a supplement 孩子从营养补 充品中得到碧 容健的抗氧化 功效
  88. 88. KEY INGREDIENTS 主要成分 Pycnogenol® Acts as a free-radical scavenger and provides antioxidant defence. 碧容健 充当自由基清除剂, 并提供抗氧化防御。 Grape Seed Extract Contains high content of compounds known as oligomeric proanthocyanidins (OPCs) and polyphenols 葡萄籽萃取物 富含名为寡聚原花色素 (OPC)的复合物与多酚 Bilberry Extract Contain flavonoid pigments known as anthocyanins. 山桑子萃取物 含有称为花青素的类黄 酮色素
  89. 89. Contains no added wheat, yeast, gluten, or milk (lactose) 无添加小麦、 酵母、麸质或 奶类(乳糖) No artificial flavours, preservatives or colouring 无人工香料、 防腐剂或色素 Suitable for Vegetarians 适合素食者 NO Pork 不含猪肉 WHY OPC-3® CHEWS ARE GREAT FOR MY CHILDREN? 为什么OPC-3®软糖对我的孩子有好处?
  90. 90. Your Children’s Digestive Tract is Delicate… 您孩子的消化道很脆弱…… Both healthy bacteria (probiotics) and potentially unhealthy bacteria populate within the digestive tract. Maintaining a balance of these two types of bacteria is essential in maintaining health. 对健康有益的细菌(益生 菌)和可能对健康有害的 细菌均存在于消化道; 维持这两种细菌的平衡对 维持健康非常重要。
  91. 91. DNA Miracles® Chewable Probiotics DNA Miracles® 嚼片益生菌(儿童配方)
  92. 92. • 每粒嚼片提供50亿 益生菌 • 采用LiveBac™ 片剂 制造技术,确保益 生菌活性 • 促进免疫系统健康 DNA Miracles® Chewable Probiotics DNA Miracles®嚼片益生菌(儿童配方) • Delivers five billion bacteria in each chewable tablet • Utilises the LiveBac™ tableting process to ensure viability of the bacteria • Promotes healthy immune system functions
  93. 93. • Provides good bacteria to help maintain bacterial balance • Supports healthy digestive functions • Promotes stomach comfort and bowel regularity • Supports healthy teeth DNA Miracles® Chewable Probiotics DNA Miracles®嚼片益生菌(儿童配方) • 提供有益菌,协助 保持细菌平衡 • 支援消化功能健康 • 促进胃部舒适感和 肠道规律性 • 支援牙齿健康
  94. 94. Contains five unique bacterial strains • Streptococcus salivarius • Lactobacillus rhamnosus • Lactobacillus salivarius • Lactobacillus paracasei • Lactobacillus plantarum DNA Miracles® Chewable Probiotics DNA Miracles®嚼片益生菌(儿童配方) 含有五种独特益菌 • 唾液链球菌 • 鼠李糖乳杆菌 • 唾液乳杆菌 • 副干酪乳杆菌 • 胚芽乳杆菌
  95. 95. Probiotics provide good bacteria to help support immunity and promote healthy digestion 益生菌提供有益的细菌来帮助支援 免疫力并促进消化系统健康 Lactobacillus Rhamnosus • highly resilient bacteria which plays a role in immune health Lactobacillus Salivarius • helps to balance bacteria in the gastrointestinal tract 鼠李糖乳杆菌 • 极具恢复力的细菌, 在免疫系统健康方面 发挥着重要作用 唾液乳杆菌 • 有助平衡肠胃道内的 细菌
  96. 96. Lactobacillus Plantarum • helps to preserve nutrients, antioxidants and vitamins Streptococcus Salivarius • supports dental health, especially in children Probiotics provide good bacteria to help support immunity and promote healthy digestion 益生菌提供有益的细菌来帮助支援 免疫力并促进消化系统健康 胚芽乳杆菌 • 有助保留营养素、抗氧化 物及维生素 唾液链球菌 • 支援牙齿健康,尤其可 保护儿童的牙齿健康
  97. 97. DNA Miracles® Chewable Probiotics DNA Miracles®嚼片益生菌(儿童配方) Gluten-Free The finished product contains no detectable gluten Vegetarian This product is vegetarian No Pork This product contains no pork or pork products 不含麸质 本产品不含可检测出 之麸质 素食可用 本产品为素食产品 不含猪肉 本产品不含猪肉或猪 肉制品
  98. 98. Case 案例 Issues 问题 Findings 发现 Recommended Supplements 推荐补充品 13 year old boy with learning difficulties – dyslexia and dycalculia 13岁男孩有学习困难 — 阅读障碍和计算障碍 Unable to focus in class and quality of sleep compromised 上课注意力不集中,睡眠品质 不佳 Probiotic supplementation early in life may reduce the risk of neuropsychiatric disorder development later in childhood possible by mechanisms not limited to gut microbiota composition. “A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial” Anna Pärtty1 , Marko Kalliomäki1 , Pirjo Wacklin2 , Seppo Salminen3 and Erika Isolauri 除了仰赖肠道微生物之外,在生命早期补充 益生菌,可降低儿童后期发生神经精神疾病 的风险。 “早期益生菌干预与儿童晚期神经精神疾病 风险之间可能存在联系:一项随机试验” Anna Pärtty1 , Marko Kalliomäki1 , Pirjo Wacklin2 , Seppo Salminen3 and Erika Isolauri DNA OPC3 chewables DNA Chewable Probiotics DNA Miracles OPC-3® 软糖 DNA Miracles® 嚼片益 生菌(儿童配方) My Personal Case Notes 我的个人案例说明 Pediatric Research, Vol 77 (6), 2015. International Pediatric Research Foundation, Inc.
  99. 99. Market Singapore® | SG.SHOP.COM Product Symposium 2019 美安新加坡™ | SG.SHOP.COM 2019产品专题会 COMPLETE CARE FOR YOUR LITTLE ONES 给宝贝完善的照顾
  100. 100. Promoting optimal health from head to toe! 促进全身心健康! This presentation is based on clinical trials performed worldwide. The health claims in this presentation have not been approved or endorsed by Singapore health authorities. 本简报乃基于全球临床试验资料。本简报中的健康声明尚未得到新加坡卫生当局的批准或认可。 Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents. 碧容健是贺发研究公司的注册商标。 The Latest Research! 最新研究结果 碧容健
  101. 101. Copyright 2010 110 O OH OH OH OH OH OHOH O OH OH OH O OH OH OH OH OH Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.
  102. 102. Pycnogenol® Supports Health From Head To Toe! 碧容健支持所有重要的身体功能和器官 Supports healthy circulatory function 健康的循环功能 Fights free radicals 对抗自由基 Supports collagen and hyaluronic acid 支持胶原蛋白和 透明质酸 Modulates inflammatory response 调节炎症反应 1.Enseleit et al., Eur Heart Journal, 2012 2.Marini et al., Skin Pharmacol Physiol, 25: 86-92, 2012 3.Grimm et al., J Inflamm 3: 1-5, 2006 4.Belcaro G et al., Minerva Med. 104: 439-46, 2013
  103. 103. Exploring New Territory 探索新领域
  104. 104. Pycnogenol® For Healthy Adventures 碧容健健康领域新探索 295 subjects flying in economy class for more than 10 hours, twice in less than 1 week  90 Pycnogenol 150 mg/day 3 days before and 3 days after the second flight  106 Stockings  99 Controls Belcaro, G., et al. (2018). Minerva Cardioangiol 66(2): 152-159. 在不到1周的时间,295位受试者乘坐经济舱两次、飞行超 过10小时  90位受试者从飞行的3天前至第二次飞行3天后,每天食 用碧容健150毫克  106 位受试者在飞行中穿着袜子  99 位对照者
  105. 105. 1.03 2.4 2.1 1.70 3.6 3.40 1.60 3.4 0.00 0.50 1.00 1.50 2.00 2.50 3.00 3.50 4.00 Pycnogenol® Prevents Leg Swelling In Long-Haul Flights 碧容健在长途飞行中预防腿部浮肿 *p<0.05 vs both controls * p<0.05 vs 两个对照组 * 150 mg/day N=295 150毫克/天 人数 = 295 * Belcaro, G., et al. (2018). Minerva Cardioangiol 66(2): 152-159. Pycnogenol® 碧容健组 Control 对照组 Stockings 穿袜子组 Normal Subjects 正常受试者 Moderate Risk Subjects 中度危险受试者 Long-haul flight: Edema Score 长途飞行:浮肿评分
  106. 106. 6.0 17.0 19.0 3.0 10.0 13.0 8.0 20.0 21.9 0.0 5.0 10.0 15.0 20.0 25.0 Long-haul flight: leg pain [% of subjects] Pycnogenol® Prevents Leg Pain In Long-Haul Flights 碧容健在长途飞行中预防腿部疼痛 *p<0.05 vs both controls p<0.05 vs 两个对照组 * * * 150 mg/day N=295 150毫克/天 人数=295 Belcaro, G., et al. (2018). Minerva Cardioangiol 66(2): 152-159. Pycnogenol® 碧容健组 Control 对照组 Stockings 穿袜子组 Normal Subjects 正常受试者 Moderate Risk Subjects 中危受试者 High Risk Subjects 高危受试者Deep Vein Thrombosis 深静脉血 栓形成 2 2 = 0 深血 凝块
  107. 107. 0.90 1.8 2.1 1.00 2.90 3.20 1.10 2.90 3.20 0.00 0.50 1.00 1.50 2.00 2.50 3.00 3.50 Long-haul flight: Jet Lag Symptom Score [1-4] 长途飞行: 时差症状评分 [1-4] Pycnogenol® Improves Jet-Lag Symptoms 碧容健改善时差问题 * * * Belcaro, G., et al. (2018). Minerva Cardioangiol 66(2): 152-159. Normal Subjects 正常受试者 Moderate Risk Subjects 中危受试者 High Risk Subjects 高危受试者 *p<0.05 vs both controls p<0.05 vs 两个对照组 150 mg/day N=295 150毫克/天 人数=295 Pycnogenol® 碧容健组 Control 对照组 Stockings 穿袜子组
  108. 108. Pycnogenol® For Healthy Adventures 碧容健健康领域新探索  Prevents edema and ankle swelling  Prevents leg pain and discomfort  Improves jet lag symptoms  Prevents thrombosis Belcaro, G., et al. (2018). Minerva Cardioangiol 66(2): 152-159.  预防浮肿及脚踝肿胀  预防腿部疼痛及不适  改善时差问题  预防血栓形成
  109. 109. Venous Health Pycnogenol® for the prevention of Post-Thrombotic Syndrome (PTS) and Recurrent Deep Vein Thrombosis (R-DVT): a SIX YEAR study Belcaro, G., et al. (2018). Minerva Cardioangiol 66(3): 238-245. 静脉健康 碧容健预防血栓后综合症(PTS)和复发性深静脉血栓形成 (R-DVT):一项为期6年的研究
  110. 110. Prevention of Post-Thrombotic Syndrome and Recurrent Deep Vein Thrombosis 预防血栓后综合症及复发性深静脉血栓形成 Patients with deep vein thrombosis were followed for 6 years: – N=222 controls with standard management – N=137 Pycnogenol 200 mg /day – N=202 Aspirin 100 mg/day – N=121 Ticlopidine (250 mg/day) – N=133 Sulodexide 500 ULS/day Belcaro, G., et al. (2018). Minerva Cardioangiol 66(3): 238-245. 6年跟进追踪深静脉血栓患者: – 人数 = 222 对照组标准管理 – 人数 = 137 碧容健组200毫克/天 – 人数 = 202 阿司匹林100毫克/天 – 人数 = 121 噻氯匹定250毫克/天 – 人数 = 133 舒洛地特上限摄取量500毫克/天 深静脉血栓形成 股静脉 血栓 症状 受累肢体肿胀 暖和 疼痛或压痛 皮肤发红,苍 白或其他变化
  111. 111. 0.00% 5.00% 10.00% 15.00% 20.00% 25.00% 6 years 6 years Occurrence of recurrent Incidence of PTS % R-DVT+PTS Pycnogenol in prevention of post-thrombotic syndrome and DVT at 6 years 碧容健预防血栓后综合症(PTS)和复发性深静脉血栓形成(R-DVT)为期6年的研究 Controls Aspirin Pycnogenol® Ticlopidine Sulodexide Prevention of Post-Thrombotic Syndrome(PTS) and Recurrent-Deep Vein Thrombosis(R-DVT) 预防血栓后综合症(PTS)及复发性深静脉血栓形成(R-DVT) *p<0.05 * * 200 mg/day N=815 200毫克/天 人数 = 815 * ** * * * * * * -11% -13% Belcaro, G., et al. (2018). Minerva Cardioangiol 66(3): 238-245. -11% Recurrent DVT 对照组 阿司匹林 碧容健组 噻氯匹定 舒洛地特 6年 经常性的DVT PTS的发病率
  112. 112. Pycnogenol® For Post-Thrombosis 血栓后使用碧容健  Decreases the incidence of post- thrombotic syndrome.  Decreases the recurrence of deep vein thrombosis  降低血栓后综合症的发病率  降低深静脉血栓的复发率
  113. 113. Think 思考 Promoting Cognitive Function with Pycnogenol® Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. 碧容健促进认知功能
  114. 114. Pycnogenol® in Minimal Cognitive Impairment 碧容健对轻度认知障碍的作用 87 subjects with Minimal Cognitive Impairment and initial cognitive dysfunction MMSE score18-23 (aged 55-75)  43 Pycnogenol® 150 mg/day for 8 weeks  44 Controls Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. 87位轻度认知障碍与认知功能紊乱早期患者 (年龄为55-75),其简短智能测验(MMSE)得分 为18-23  43位食用碧容健150毫克/天,持续8周  44位对照者
  115. 115. Cognitive Decline With Age 认知能力随老化而下降 http://www.mind.uci.edu/dementia/mild-cognitive-impairment/ • Silent phase: brain changes without measurable symptoms • 潜伏期:尚无可衡 量大脑变化的症状 • Cognitive changes become a concern • 1 or more cognitive domains significantly impaired. ADLs* preserved. • 认知功能改变引起关注 • 1个或多个认知领域显著 受损 • Cognitive decline significantly affect ADLs* • 认知下降明显影响ADL* *ADL : Activities of Daily Life ADL:日常生活活动 正常老化 每个人在衰老过程中都会经历轻微的认知变化 临床前 温和 中等 中度严重 严重 痴呆 轻度认知障碍 时间 (年度)
  116. 116. MCI diagnosis: Mini-Mental State Examination MCI诊断:迷你精神状态检查 Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284.
  117. 117. Pycnogenol® Helps Improve Cognitive Function In Elderlies With MCI 碧容健有助于改善轻度认知障碍(MCI)老年患者的认知功能 *p<0.05Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. * Minimal Cognitive Impairment (Mini-Mental Status Exam; MMSE) 轻度认知障碍 (简短智能测验;MMSE) 25.64 23.00 21.50 22.00 22.50 23.00 23.50 24.00 24.50 25.00 25.50 26.00 Total MMSE Score (8 weeks) MMSE 总分 (8 周) Pycnogenol® Controls +18% +2.48% 150 mg/day N=87 elderly men 150毫克/天{ut}人数 = 87位老年男性 Study start 碧容健组 对照组 研究起始
  118. 118. -23% -15% -14% -31% -3% -6% -6% 0% -35% -30% -25% -20% -15% -10% -5% 0% Pycnogenol® Control Pycnogenol® Improves Cognitive Function In The Elderly 碧容健改善老年人的认知功能 *p<0.05 * * ** 150 mg/day N=87 male seniors 150毫克/天 人数 = 87位老年男性 % Improvement of 16-IQCODE remembering items after 8 weeks 8周后,16项老年人认知功能減退知情者问卷(IQCODE)的结果改进百分比 Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. Address / Tel No. 地址/电话号码 Recent Conversations 近期对话 Recent Events 近期事件 Family / Friends 家人/朋友 碧容健组 对照组
  119. 119. -29% -39% -24% -13% -10% -6.5% -9.7% -3% -45% -40% -35% -30% -25% -20% -15% -10% -5% 0% Pycnogenol® Control Pycnogenol® Improves Cognitive Function In The Elderly 碧容健改善老年人的认知功能 *p<0.05 * * * * 150 mg/day N=87 male seniors 150毫克/天 人数 = 87位老年男性 % Improvement of 16-IQCODE remembering items after 8 weeks 8周后,16项老年人认知功能減退知情者问卷(IQCODE)的结果改进百分比 Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. Day / Month 日/月 Remembering where things are 记得东西的摆放位置 Find things in different places 找得到放在不同位置的物品 Using simple house equipment 会使用简单的家用设备 碧容健组 对照组
  120. 120. -24% -29% -21% -24% -3% -7.1% -9.1% -3.8% -35% -30% -25% -20% -15% -10% -5% 0% Pycnogenol® Control Pycnogenol® Improves Cognitive Function In The Elderly 碧容健改善老年人的认知功能 *p<0.05 * * * * 150 mg/day N=87 male seniors 150毫克/天 人数 = 87位老年男性 Learning new gadgets 学习使用新工具 Learning new things 学习新事物 Following stories 能听懂别人说的故事 Simple decisions 做出简单的决定 Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. 碧容健组 对照组 % Improvement of 16-IQCODE remembering items after 8 weeks 8周后,16项老年人认知功能減退知情者问卷(IQCODE)的结果改进百分比
  121. 121. -39.4% -26.7% -31.0% -28.0% -12.5% -7.7% -7.4% -8.7% -45.0% -40.0% -35.0% -30.0% -25.0% -20.0% -15.0% -10.0% -5.0% 0.0% Money Bank, Payments, pensions House matters (Food, shopping..) Understanding situations, status, reasoning Pycnogenol® Controls *p<0.05 * * * * Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. Improvement in cognitive function(%;8 weeks) (16-IQCODE{Informant Questionnaire in the Elderly}) Pycnogenol® Helps Improve Cognitive Function In The Elderly 碧容健改善老年人的认知功能 150 mg/day N=87 male seniors 150毫克/天 人数 = 87位老年男性 改善认知功能(%;8周) 16-IQCODE({老年人认知功能知情者问卷}) 钱 银行、支付养老金 家务(食物、购物) 了解情况,地位,推理 碧容健组 对照组
  122. 122.  Pycnogenol® supports healthy cognitive function throughout the lifetime  Reduces free radical stress  Promotes healthy blood flow to brain  Metabolites pass through blood-brain- barrier  May help improve mild cognitive dysfunction Clinical studies on all ages:  Children ADHD  University students  Professionals  Baby boomers  Elderly NEW: Cognitive Function Infographic! https://www.pycnogenol.com/media/infographics-photos-logos/?L=922 https://www.pycnogenol.com/applications/cognitive-function/?L=922  碧容健在整个生命周期都能支援健 康的认知功能  减少自由基压力  促进健康的脑部血流量  代谢物通过血脑屏障  可能帮助改善轻度认知功能障碍 各年龄段的临床研究:  儿童注意力不足过动症  大学生  专业人士  婴儿潮世代  老年人 最新资讯:认知功能资讯图表! Pycnogenol® Shows Benefit in Mild Cognitive Impairment 碧容健对轻度认知障碍的益处
  123. 123. Pycnogenol.com => MEDIA tab https://www.pycnogenol.com/media/infographics-photos-logos/?L=922 https://www.pycnogenol.com/applications/cognitive-function/?L=922 Pycnogenol.com => “媒体”标签 碧容健在任何年龄刺激认知功能 注意力 记忆 执行功能 氧化应激 认知功能 精神表现 心情 专心度 碧容健法国海洋松树皮提取物认知功能的科学基础成分
  124. 124. https://www.pycnogenol.com/media/infographics-photos-logos/?L=922 https://www.pycnogenol.com/applications/cognitive-function/?L=922 改善ADHD症状 (关注缺陷多动障碍) 注意力不集中 极度活跃 产生压力荷尔蒙 多巴胺 肾上腺素 去甲肾上腺素 青少年 Pycnogenol.com => MEDIA tab Pycnogenol.com => “媒体”标签
  125. 125. 学生们 改善学生的特定认知 测试结果 节奏听觉序列 加法测试 图片回忆 空间识别记忆 心理灵活性 Pycnogenol.com => MEDIA tab Pycnogenol.com => “媒体”标签
  126. 126. Pycnogenol.com => MEDIA tab https://www.pycnogenol.com/media/infographics-photos-logos/?L=922 https://www.pycnogenol.com/applications/cognitive-function/?L=922 Pycnogenol.com => “媒体”标签 改善健康专业人员 的认知功能 专业人士 年龄35-55岁 警觉 心情 财富处理 焦虑
  127. 127. https://www.pycnogenol.com/media/infographics-photos-logos/?L=922 https://www.pycnogenol.com/applications/cognitive-function/?L=922 婴儿潮世代 年龄55-70岁 管理日常任务 判定 睡眠质量 婴儿潮一代认知功 能的改善 待人接物 Pycnogenol.com => MEDIA tab Pycnogenol.com => “媒体”标签
  128. 128. https://www.pycnogenol.com/media/infographics-photos-logos/?L=922 https://www.pycnogenol.com/applications/cognitive-function/?L=922 婴儿潮世代 年龄55-70岁 婴儿潮时期轻度认知 障碍(MCI)症状的改 善 记住朋友和家人 记住东西的位置 学习新技术 待人接物 Pycnogenol.com => MEDIA tab Pycnogenol.com => “媒体”标签
  129. 129. Pycnogenol® for Heart Health and Circulation 碧容健在心脏健康和循环方面的功效 +32% -5.1% Reduces high blood pressure by 5.1% 高血压降低 5.10% [Hosseini et al. 2001] Improves cholesterol levels. Reduces “bad” LDL by 7% and increases “good” HDL by 10% 改善胆固醇 水平. 坏的”低密度脂 蛋白}降低7%,“好 的”高密度脂蛋白提高 10% [Devaraj et al. 2001] LDL -7% HDL +10% Inhibits platelet aggregation helping to prevent blood clots 抑制血小板凝集,有助于 预防血栓 [Pütter et al. 1999] Restores compromised kidney function 修复受损的 肾功能 [Stuard et al. 2010] -75% Reduces progression of atherosclerosis by 75% preventing artery- clogging plaque 使动脉粥样硬化的发展进程 减缓75%, 防止动脉堵塞斑块 [Belcaro et al. 2010] Improves blood flow Increases endothelium- dependent vasodilation by 32%. 改善血流量 内皮依赖性血管舒张增加 32% [Enseleit et al. 2012]
  130. 130. Pycnogenol® benign prostatic hyperplasia 碧容健与良性前列腺增生 – 75 patients with BPH • 22 Pycnogenol® 150 mg/day • 27 Controls • 26 dutasteride (0.5 mg/day) and finasteride of (5 mg day) – 8 weeks follow-up Effects of Pycnogenol® on BPH symptoms and ultrasound investigations Ledda, A., et al. (2018). Minerva Med 109(4): 280-284. – 75例BPH患者 • 22碧容健150毫克/天 • 27 位控制组 • 26度他雄胺(0.5毫克/天)和非那甾胺 (5毫克一天) – 随访8周 碧容健对BPH症状和超声检查的影响
  131. 131.  Prostate a gland that is part of the male reproductive system  surrounds the upper portion of the urethra (the tube that carries urine out of the body).  前列腺是男性生殖系统的一部分  环绕在尿道的上部(将尿液排出体外的管子)。 Ledda, A., et al. (2018). Minerva Med 109(4): 280-284. 尿道被压缩 阻塞尿液流动 难以启动排尿段滴沥 膀胱不完全排空 Pycnogenol® benign prostatic hyperplasia 碧容健与良性前列腺增生 将康的前列腺 缺佳的前列腺
  132. 132. Common Signs And Symptoms Of BPH Include: 良性前列腺增生的常见体征和症状包括:  Frequent or urgent need to urinate.  Increased frequency of urination at night (nocturia)  Difficulty starting urination.  Weak urine stream or a stream that stops and starts.  Dribbling at the end of urination.  Straining while urinating.  Inability to completely empty the bladder.  尿频或尿急  夜间排尿频率增加 (夜尿症)  排尿开始困难  尿流细弱或尿流间断  排尿后段滴沥  排尿时紧张  无法完全排空膀胱 Ledda, A., et al. (2018). Minerva Med 109(4): 280-284.
  133. 133. -51% -35% -41% -60% -50% -40% -30% -20% -10% 0% Pycnogenol® Controls Dudasteride + finasteride Pycnogenol® Controls Dudasteride + finasteride Pycnogenol® Improves Bladder Emptying In BPH 碧容健促进患者排空膀胱 *p<0.05 vs both controls p<0.05 vs 两个对照组 150 mg/day N=75 150毫克/天 人数 = 75 * Ledda, A., et al. (2018). Minerva Med 109(4): 280-284. % change of residual bladder volume after 8 weeks 8周后膀胱内残余尿液容量变化百分比 碧容健 对照者 度他雄胺+非那 雄胺 碧容健 对照者 度他雄胺+非那雄胺
  134. 134. -42% -37% -31% -24% -24% -31% -31% -9% -12% -9% -9% -9% -20% -18% -6% -14% -19% -6% -17% -6% -9% -45% -40% -35% -30% -25% -20% -15% -10% -5% 0% Emptying Frequency Intermittency Urgency Weak flow Straining Nocturia Pycnogenol® Controls Dudasteride + finasteride Pycnogenol® Improves Urinary Symptoms In BPH 碧容健改善良性前列腺增生症状 ** * * * * * Ledda, A., et al. (2018). Minerva Med 109(4): 280-284. Improvement % of urinary BPH symptoms after 8 weeks 8周后良性前列腺增生症状改善的百分比 倾卸 次数 间歇 毅力 流量不足 使劲 夜尿 碧容健 对照者 度他雄胺+非那雄胺 *p<0.05 vs both controls p<0.05 vs 两个对照组 150 mg/day N=75 150毫克/天 人数 = 75
  135. 135. Pycnogenol® for Benign Prostatic Hyperplasia 碧容健与良性前列腺增生  Improves urinary symptoms  Improves bladder emptying  Decreases oxidative stress  改善泌尿系统症状  促使膀胱排空  降低氧化压力 Ledda, A., et al. (2018). Minerva Med 109(4): 280-284.
  136. 136. New hope for autoimmune conditions 自体免疫性 疾病的 新希望 正常的免 疫反应 抗原 侵入 抗体 形成 抗体去除 入侵抗原 抗体保留 并保护 自身免 疫性疾 病 免疫系统形 成自身抗原 的抗体 抗体攻击 自身抗原 炎症和组 织损伤
  137. 137. Pycnogenol® for Sjögren’s Syndrome 碧容健与修格兰氏症候群 30 subjects subjects with Sjögren’s syndrome (SSy) in remission with significant symptoms affecting their quality of life  16 Pycnogenol® 150 mg/day for 8 weeks  14 Controls Luzzi, R., et al. (2018). Minerva Cardioangiol 66(5): 543-546. 30位受试者,处于修格兰氏症 候群(SSy)的缓解期, 症状明显,已影响到其生活品 质  16位食用碧容健150毫克/天, 持续8周  14位对照者
  138. 138. Sjögren’s Syndrome – Symptoms 修格兰氏症候群 — 症状 眼睛干涩 干燥的鼻子 口干、 蛀牙、 咀嚼 干燥的皮肤 胃不舒服 阴道干涩 记忆困难 讲话困难 胃灼热吞咽 呼吸状况 疼痛和关节炎 肝脏问题 极端麻木
  139. 139. 69% 56% 75% 38% 100% 86% 100% 93% 0% 20% 40% 60% 80% 100% 120% Topical eye dryness control Eye hypromellose, methylcellulose Ointment at bedtime Topical cyclosporine Pycnogenol® Controls Pycnogenol® Decreases The Need Of Topical Treatment For Eye Dryness In Sjögren’s 碧容健可减少修格兰氏症候群患者治疗干眼症的外用药使用量 *p<0.05 150 mg/day N=30 150毫克/天 人数 = 30 * * * * Luzzi, R., et al. (2018). Minerva Cardioangiol 66(5): 543-546. % of subjects in need of topical eye dryness control after 8 weeks 8周后,使用外用药治疗干眼症的受试者百分比 碧容健 对照者 热带眼干燥控制 眼用羟丙甲纤维素, 甲基纤维素 睡前的药膏 局部环孢菌素
  140. 140. 100% 56% 100% 86% 0% 20% 40% 60% 80% 100% 120% Baseline (previous 3 months) 8 weeks % of subjects in need of topical eye hypromellose, methylcellulose Pycnogenol® Controls Pycnogenol® Decreases The Need of topical dry eye treatment in Sjögren’s 碧容健可减少修格兰氏症候群患者治疗干眼症的外用药使用量 *p<0.05 150 mg/day N=30 150毫克/天 人数 = 30 * Luzzi, R., et al. (2018). Minerva Cardioangiol 66(5): 543-546. 需要局部使用羟丙醇、甲基纤维素受试者百分比 基线(前3个月) 8周 碧容健 对照者
  141. 141. Pycnogenol® Decreases Mouth Dryness In Sjögren 碧容健缓解修格兰氏症候群患者口干的症状 *p<0.05 150 mg/day N=30 150毫克/天 人数 = 30 * * Luzzi, R., et al. (2018). Minerva Cardioangiol 66(5): 543-546. 75% 31% 100% 57% 0% 20% 40% 60% 80% 100% 120% 8 weeks 8 weeks Mouth dryness (need for fluids) saliva substitutes Pycnogenol® Controls % of subjects in need of fluids for mouth dryness control 需要液体缓解口干症的受试者百分比 8周 8周 口干(需要补充水分) 唾液替代品 碧容健 对照者
  142. 142. 0% 6% 29% 29% 0% 5% 10% 15% 20% 25% 30% 8 weeks 8 weeks Corticosteroids Hydroxychloroquine (arthralgia) Pycnogenol® Controls Pycnogenol® decreases the need of systemic management in Sjögren 碧容健可减少修格兰氏症候群患者系统治疗需要 *p<0.05 150 mg/day N=30 150毫克/天 人数 = 30 * * Luzzi, R., et al. (2018). Minerva Cardioangiol 66(5): 543-546. % of subjects in need of systemic management during 8 weeks 8周内需系统治疗的受试者百分比 8周 8周 碧容健 对照者
  143. 143. 碧容健 对照者 -43% -13% -13% -4% -4% -2% -45% -40% -35% -30% -25% -20% -15% -10% -5% 0% Erythrocytes sedimentation rate SR [mm/hour] Oxidative stress [Carr units] Rheumatoid factor [IU/L] Pycnogenol® Controls Pycnogenol® Decreases Inflammation In Sjögren 碧容健减少修格兰氏症候群患者的炎症 *p<0.05 150 mg/day N=30 150毫克/天 人数 = 30 * * * Luzzi, R., et al. (2018). Minerva Cardioangiol 66(5): 543-546. Improvement % inflammation markers after 8 weeks 8周后炎症标志物得到改善的百分比 红细胞沉降率SR(mm / hour) 氧化应激 类风湿因子(IU / L)
  144. 144. Pycnogenol® for Sjögren’s syndrome 碧容健与修格兰氏症候群  Decreases the need of topical treatment for eye dryness  Decreases mouth dryness by decreasing the need of fluids and saliva substitutes  Decreases the need of systemic management  Reduces inflammation  减少治疗干眼症的外用药需求量  通过减少对液体和唾液替代品的需求来缓解口干症  减少对系统治疗的需求  减少炎症
  145. 145. Pycnogenol® for Irritable Bowel Syndrome (IBS) 碧容健与大肠激燥症(IBS) – 77 patients with IBS • 24 Pycnogenol® 150 mg/day • 26 Buscopan 10 mg/day • 27 Antispasmina colica forte (papaverin 50 mg + belladonna extract) – 4 week treatment Effects of Pycnogenol® on IBS symptoms I S Irritable bowel syndrome 大肠激燥症 IBS is a common functional disorder of the digestive tract. 1 in 5 每5人中就有1人 Suffer from IBS 患大肠激燥症 Common symptoms 常见症状 Painful cramps Bloating Diarrhea Constipation Mucus in stool 2-3 times more likely to suffer from IBS 患大肠激燥症 的几率增加 2-3倍 Current treatments 目前疗法 Medication: Laxatives Antispasmodics Antidepressants Others Special Diet Exercise Psychotherapy Stress reduction Belcaro, G., et al. (2018). Panminerva Med 60(2): 65-69. – 77位大肠激燥症患者: • 24位食用碧容健150毫 克/天 • 26位服用补斯可伴10 毫克/天 • 27位服用 Antispasmina colica forte(罂粟碱50毫克 +颠茄浸膏) – 使用4周 碧容健对大肠激燥症症状的 效用 大肠激燥症是 消化道常见的 功能障碍。 疼痛性痉挛 腹胀 腹泻 便秘 粪便中有粘液 药物: 缓泻剂 解痉药 抗抑郁药 其他 特殊饮食 运动 精神疗法 减少压力
  146. 146. -41% -27% -4% -13% -60% -54% -42% -31% -31% -21% -59% -38% -46% -48% -41% -41% -69% -75% -80% -70% -60% -50% -40% -30% -20% -10% 0% Recurrent abdominal pain Abdominal pain at pressure Altered bowel movement and distenstion Meteorism Cramps All symptoms Improvement % of IBS symptoms after 4 weeks 4周后改善大肠激燥症症状的百分比 Buscopan Antispasmina colica forte Pycnogenol® Bloating and gas Pycnogenol® Improves IBS Symptoms 碧容健改善大肠激燥症的症状 *p<0.05 Belcaro, G., et al. (2018). Panminerva Med 60(2): 65-69. * 150 mg/day N=77 150毫克/天{ut}人数 = 77 * * * * 反复发作的腹痛 压力时腹痛 改变肠蠕动和扩张 腹胀和气体飙升 抽筋 所有症状 解痉灵 强烈的绞痛抗痉挛 碧容健
  147. 147. 31% 33% 21% 0% 5% 10% 15% 20% 25% 30% 35% Rescue medication % of patients using rescue medication during 4 weeks 4周内使用急救药物的患者百分比 Buscopan Antispasmina colica forte Pycnogenol® Pycnogenol® Decreases The Need Of Rescue Medication In IBS 碧容健减少大肠激燥症患者对急救药物的需求 *p<0.05 150 mg/day N=77 150毫克/天{ut}人数 = 77 * Belcaro, G., et al. (2018). Panminerva Med 60(2): 65-69. 救援药物 解痉灵 强烈的绞痛抗痉挛 碧容健
  148. 148. 15% 22% 8% 0% 5% 10% 15% 20% 25% Consultations, hospital % of patients consulting during 4 weeks 4周内咨询的患者百分比 Buscopan Antispasmina colica forte Pycnogenol® Pycnogenol® Decreases The Need Of Consultation In IBS 碧容健减少大肠激燥症的诊疗 *p<0.05 150 mg/day N=77 150毫克/天{ut}人数 = 77 * Belcaro, G., et al. (2018). Panminerva Med 60(2): 65-69. 解痉灵 强烈的绞痛抗痉挛 碧容健 咨询,医院
  149. 149. Pycnogenol® For Irritable Bowel Syndrome 碧容健与大肠激燥症  Improves IBS symptoms  Decreases the need of rescue medication  改善大肠激燥症症状  减少对大肠激燥症救援药物的需求
  150. 150. IBS Travel Veins BPH Sjogrens MCI Summary – Herding Cats? 总结 — 放猫?不可能完成的任务? 轻度认 知障碍 大肠激燥症 静脉 良性前 列腺增 生 修格兰氏 症候群 旅行
  151. 151. Pycnogenol® for healthy adventures 碧容健健康领域新探索  Prevents edema and ankle swelling  Prevents leg pain and discomfort  Improves jet lag symptoms  Prevents thrombosis  预防浮肿及脚踝肿胀  预防腿痛及腿部不适  改善时差问题  预防血栓形成
  152. 152. Venous Health 静脉健康 Pycnogenol® for the prevention of Post-Thrombotic Syndrome (PTS) and Recurrent Deep Vein Thrombosis (R-DVT): a SIX YEAR study 碧容健预防血栓后综合症(PTS)和复发性深静脉血栓形成(R-DVT): 一项为期6年的研究
  153. 153. Pycnogenol® Helps Improve Cognitive Function In Elderlies With MCI 碧容健有助于改善轻度认知障碍(MCI)老年患者的认知功能 *p<0.05Hosoi, M., et al. (2018). J Neurosurg Sci 62(3): 279-284. * Minimal Cognitive Impairment (Mini-Mental Status Exam; MMSE) 25.64 23.00 21.50 22.00 22.50 23.00 23.50 24.00 24.50 25.00 25.50 26.00 Total MMSE Score (8 weeks) MMSE总分 (8 周) Pycnogenol® Controls +18% +2.48% 150 mg/day N=87 elderly men 150毫克/天 人数 = 87位老年男性 Study start 研究起始 轻度认知障碍 (简短智能测验;MMSE) 碧容健 对照者
  154. 154. Pycnogenol® for Benign Prostatic Hyperplasia 碧容健与良性前列腺增生  Improves urinary symptoms  Improves bladder emptying  Decreases oxidative stress  改善泌尿系统症状  促进膀胱排空  减少氧化压力
  155. 155. Pycnogenol® for Sjögren’s syndrome 碧容健与修格兰氏症候群  Decreases the need of topical treatment for eye dryness  Decreases mouth dryness by decreasing the need of fluids and saliva substitutes  Decreases the need of systemic management  Reduces inflammation  减少治疗干眼症的外用药需求量  通过减少对液体和唾液替代品的需求来缓解口干症  减少对系统治疗的需求  减少炎症
  156. 156. Pycnogenol® for Irritable Bowel Syndrome 碧容健与大肠激燥症  Improves IBS symptoms  Decreases the need of rescue medication  改善大肠激燥症症状  减少对大肠激燥症救援药物的需求
  157. 157. IBS Travel Veins BPH Sjogrens MCI  Antioxidant1  Anti-Inflammatory2  Cardiovascular Health3  Blood Sugar Control4 IBSVeins BPH SjogrensMCITravel Clinically Proven Multi-Functional Pycnogenol® 临床证实碧容健的多种功效 Better Health 3.Enseleit et al., Eur Heart Journal, 2012 4.Liu et al., Diabetes Care 27: 839, 2004 1.Belcaro G et al., Minerva Med. 104: 439-46, 2013 2.Grimm et al., J Inflamm 3: 1-5, 2006  抗氧化物1  抗炎2  心血管健康3  血糖控制4 旅行 轻度认 知障碍 良性前列 腺增生 修格兰 氏症候 群 静脉 大肠激 燥症
  158. 158. INTERNATIONAL WEBSITE IN 10 LANGUAGES 拥有10种语言的国际网站 Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents. Pycnogenol®是贺发研究公司的注册商标。 Pycnogenol.com碧容健 碧容健法国海洋松树皮提取物,是一种安全且以证据为基础的优质成分 ,是天然抗氧化剂的独特混合物。 碧容健,黄金标准成分
  159. 159. Reach New Heights With Pycnogenol® 碧容健助您达到健康新高度
  160. 160. Question Why is sugar present in the Isotonix products?
  161. 161. Question Why are natural sweeteners present in Isotonix products?
  162. 162. Question What is the general pH of the Isotonix Products?
  163. 163. Question Can I take Isotonix products in soda, juice, coffee, etc., rather than water?
  164. 164. Question How does the Isotonix Bromelain Plus interact with the medications such as warfarin?
  165. 165. Question How do I know if the Market Singapore supplement is vegetarian?
  166. 166. Question Is "Isotonix" being patent protected?
  167. 167. Question Not all Market Singapore supplements are available in Isotonix form. Why?
  168. 168. Question Which ingredients contribute to the bright red colour to the Ultimate Aloe Powder – Strawberry Kiwi flavour?
  169. 169. Question Can a person with medical condition start on Market Singapore supplements?
  170. 170. Question Can pregnant and breastfeeding individuals consume Market Singapore supplements?

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