2. Rapid, uncontrolled
growth of abnormal
cells in the bladder
Begins in the lining
of the bladder &
Invasive bladder
spread through the
lining into the
cancer : spread to
muscular wall of the lymph nodes, other
bladder.
organs in the pelvis
or other organs
(liver and lungs)
3. INCIDENCE
• In India bladder cancer is the fifth most
common cancer In men according to Delhi
based registry with age adjusted incidence
rate of 5.8/100,000
• Incidence is much lower in females 1.5
cases/100,000
• Male to female ratio= 8.6:1
6. In the Western world, tobacco use is the single
most important cause of bladder
cancer, accounting for an estimated 40-70% of
all cases.
Smokers' risks of bladder cancer are 2-3 times
higher compared to nonsmokers
7. CLASSIFICATION
90% of bladder cancers are transitional cell
carcinoma. The other 10% are squamous cell
carcinoma, adenocarcinoma, sarcoma, small
cell carcinoma,
9. Stage CIS: Flat cancer limited to the innermost lining of the bladder. It is high grade.
Stage T1: Cancer penetrated into the submucosal tissue.
Stage T2: Cancer penetrated the muscular bladder wall.
Stage T3: Cancer penetrated through muscular bladder wall into the surrounding
fat.
Stage T4: Cancer penetrated into the adjacent structures (prostate, uterus, or
vagina). Regional lymph nodes not involved yet.
Stage T1-4N1-2M1-2: Cancer spread out of abdomen/pelvic wall to lymph nodes or
distant organs like liver, lungs, or bones.
20. Radiation treatment can be used:
As part of the treatment for early stage bladder cancer, after
limited surgery
As the main treatment for people with early stage cancers who
can’t have surgery
As part of the treatment for advanced bladder cancers
To help prevent or treat symptoms caused by advanced bladder
cancers