An opportunistic pathogen isolated from the gut of
Shin yie type 2 diabetes mellitus
1. Type 2 Mellitus
What?
How?
Why?
Shin Yie Chin
Biomedical Sciences, University at Buffalo
September 29, 2012 Internship in Luna Medical Care PC
2. What is it?
• Most common form of diabetes
• 25.8 millions in the U.S. have diabetes (2011)
• Body does not produce enough insulin OR
• The cells ignore the insulin
• Insulin: needed for the body to use glucose to
produce energy
3. Eat Food
Body breaks
down all the
HEALTHY sugars and
INDIVIDUAL starch into
GLUCOSE
INSULIN
GLUCOSE in takes
cells GLUCOSE
make from the
ENERGY blood into
cells
4. Eat Food
Body breaks
down all the
DIABETIC sugars and
INDIVIDUAL starch into
GLUCOSE
GLUCOSE in INSULIN
blood takes
HIGH BLOOD GLUCOSE
SUGAR from the
blood into
cells
6. Causes?
• Lifestyle factors and Genetics
• Obesity – runs in
families, families tend to have
similar eating and exercise habits
• Bad eating habits, poor
diet, not exercising
• Genetics: runs in
families, already in your
gene, can’t change
• Lifestyle:
you can do something
about it!
8. Risk Factors
• Ethnicity: More common in African Americans,
Latinos, Native Americans, Asian Americans,
Native Hawaiians.
• Age: risk begins to rise at about 45years old
• Family history
• Obesity / overweight
• Inactive lifestyle
• High alcohol intake
• High fat and
carbohydrate diet
• High blood pressure
9. Symptoms
• Frequent urination
• Unusual thirst
• Extreme hunger
• Unusual weight loss
• Extreme fatigue and irritability
• Frequent infections
• Blurred visions
• Cuts/bruises that are slow to heal
• Tingling/numbness in the hands/feet
• Recurring skin, gum, or bladder infections
10. Myths
• 1. Diabetes is not that serious of a disease.
– Fact: Diabetes causes more deaths a year than breast cancer
and AIDS combined. 2 out of 3 people with diabetes die from
heart disease or stroke.
• 2. If you are overweight or obese, you will
eventually develop Type 2 Diabetes
– Fact: Obesity is a risk
factor, but other risk
factors also play a role,
such as family history,
ethnicity and age.
Many overweight people
never develop type 2
diabetes.