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Innovative Medicines Initiative Graham Hughes UK National Contact Point Health "By joining the best academic teams with high-level industry scientists, IMI is building the research capacity needed to cure the major diseases of our time."  Michel Goldman, IMI Executive Director
Innovative Medicines Initiative
IMI in the Health Theme Activity 1: Biotechnology,  generic tools  & technologies  for health  Activity 2: Translating  research for human health   Activity 3: Optimising  the delivery  of health care  cross-cutting issues:   international cooperation, SMEs,  child  health,  ageing  populations,  gender -related health issues Activity 4:   Support actions & response to policy needs The Innovative Medicines Initiative
Why  is IMI needed?
What  are the Expected Results? ,[object Object],[object Object],[object Object],[object Object],[object Object]
How  to Achieve  Results ,[object Object],[object Object],[object Object],[object Object]
How  is it funded? ,[object Object],[object Object]
IMI Governance
IMI Research Agenda
IMI Projects: Key facts ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IMI Research Consortium
IMI Call Process
1 st  Call (2008) 15 Projects 395 teams 24 SMEs 11 patient organisations EU Budget  = €281 Million  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],UK SMEs CXR Biosciences Psynova Neurotech Synairgen Reasearch Choice Pharma
2 nd   Call (2009) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],EU Budget  = €172 Million  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],UK SMEs Cyprotex Discovery Mango Business Solutions Simcyp Ltd Assero Ltd Academic Concept Knowledge Ltd
3 rd   Call (2010) Launched  22 Oct 2010 EoI Deadline  18 Jan 2011 Evaluations  March/April EU Budget  = €114 Million  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
4 th  Call
Launch Date 17 th  June 2011
Support ,[object Object]

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IMI Graham Hughes

  • 1. Innovative Medicines Initiative Graham Hughes UK National Contact Point Health "By joining the best academic teams with high-level industry scientists, IMI is building the research capacity needed to cure the major diseases of our time." Michel Goldman, IMI Executive Director
  • 3. IMI in the Health Theme Activity 1: Biotechnology, generic tools & technologies for health Activity 2: Translating research for human health Activity 3: Optimising the delivery of health care cross-cutting issues: international cooperation, SMEs, child health, ageing populations, gender -related health issues Activity 4: Support actions & response to policy needs The Innovative Medicines Initiative
  • 4. Why is IMI needed?
  • 5.
  • 6.
  • 7.
  • 10.
  • 13.
  • 14.
  • 15.
  • 16. 4 th Call
  • 17. Launch Date 17 th June 2011
  • 18.

Notas do Editor

  1. One of 5 JU, others in energy, aeronautics, IT and electronics New approach to financing R&D Long term public-private partnerships in research at European Level Co-ordinated research efforts responding to industry needs Implemented through new legal entities – Joint Undertakings , established under European Law
  2. IMI funded from the FP7 pot Topics are complementary to the health call themes IMI JU consults with health Directorate to ensuer no overlaps
  3. Only one drug candidate in 10,000 will reach the market/patient.  It takes up to 10 -13 years to develop a drug and bring it to the market.  It requires an investment of around €1 billion on average for each new drug Make drug discovery and development process in Europe more efficient Enhance European competitiveness in the pharmaceutical sector Drug development process is getting harder and harder – create an environment of open innovation to overcome key issues
  4. Safety : this addresses bottlenecks related to accurately evaluating the safety of a compound during the pre-clinical phase of the development process, but also impacts the later phases in clinical development. Efficacy : this addresses bottlenecks in the ability to predict how a drug will interact in humans and how it may produce a change in function. Knowledge Management : this addresses the more effective utilisation of information and data for predicting safety and efficacy. Training + Education : this closes existing training gaps in the drug development process.
  5. Projects must include at least two EFPIA member companies, and two legal entities who are not members of EFPIA and who are eligible to receive IMI funding Any organisation carrying out activities relating to IMI objectives, in EU MS or AC can participate Others may participate if agreed by IMI governing board Participants must have the capacity to carry out the work themselves Project budgets will aim at a 50:50 ratio between in-kind contributions from EFPIA Members and the financial contribution from IMI. In kind contributions from EFPIA members will be in the form of R&D resources such as personnel, laboratories, materials and clinical research
  6. STAGE 1 Document on official forms and submission procedure Scientific /technological case (3 pages) Partnership case (I page plus ½ page per participant) Summary of workplan (2 pages including indicative budget plan) Ethical Issues (1/2 page) No involvement from EFPIA companies at this stage Evaluation Panels Independent experts and EFPIA coordinators Evaluation criteria; science technology, partnership, work plan Outcome Ranking and selection of the best EoIs EFPIA coordinators do not contribute to the final ranking Only one project per topic will be funded STAGE 2 Highest ranked EoI will be invited to jointly develop a full Project Proposal with the EFPIA consortium associated with the topic. Full proposal is subject to a final review by independent experts Successful consortia invited to conclude a Grant Agreement with the IMI.