Altered mental status (AMS) refers to changes in mental state ranging from disorientation to unresponsiveness. AMS can be caused by traumatic head injury, poisoning, drug overdose, infection, shock, hypoxia, stroke, or diabetes. Signs of AMS include abnormal vital signs, unequal or sluggish pupils, abnormal skin condition, seizure activity, and irregular blood glucose levels depending on the cause. Patients exhibiting AMS fall under implied consent and must be transported to the hospital for further assessment and treatment.