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Genetically Engineered Foods:
  Past, Present, and Future
   Sacramento Sustainability Forum
         November 17, 2011
Introduction
• First GE Food: Labeled and the GE protein in it
      regulated as a food additive
• GE Foods in the U.S. since: not labeled, GE
      proteins not considered food additives and
      not regulated by FDA
• GE Products in the Pipeline: Labeling?
      Regulation? Sustainability?
World’s First Genetically Engineered Whole Food
   MacGregor’sR Tomatoes Grown from Flavr SavrTM Seeds were
     accompanied by tomato-shaped brochures like this one
“Grown From Genetically Modified Seeds”
             Right on the Sticker
Engineered for longer shelf-life and vine-life
The gene encoding a softening enzyme in tomato was flipped upside
down and backwards and re-inserted into tomato plants, effectively
                   shutting down the enzyme
1-800-34TOMATO in the accompanying brochure
     For consumers who wanted even more information
Use of antibiotic-resistance protein explained
 Gene isolated from E. coli conferred resistance to the antibiotic
                            kanamycin
After the Flavr SavrTM Tomato
• No other GE protein (viral, bacterial, etc.) has
     been regulated as a food additive by FDA
• No other GE food has been labeled in grocery
     stores in the U.S.
• No regulation of GE foods (with a couple of
     exceptions) is required by FDA
• Regulation of GE crops by USDA and EPA is
     only triggered by products containing a
     “pest” or “pesticide,” respectively
Sustainability of Current GE Crops
• Resistance to viruses (squash, papaya):
      reduces use of pesticides
• Resistance to insects (corn, cotton, eggplant):
      reduces use of pesticides but can affect
      non-target insects
• Tolerance of herbicides (corn, soybean):
      increases use of herbicides and can lead to
      “super weeds” but can allow low-till and
      no-till farming
Possible Health Issues and GE Products
• Resistance to antibiotics (Bt 10)
• Inadvertent introduction of allergens
     (StarLink)
• Inadvertent introduction of mutations due to
     fact that current GE methods are
     mutagenic
• Inadvertent introduction of pharmaceutical
     proteins into the food supply (pig vaccine)
GE Products in the Pipeline
•   Drought-tolerant corn
•   Virus-resistant plum
•   Canola with healthier oil
•   High-lycine corn (more complete protein)
•   Crops resistant to additional pesticides (2,4-D,
       quizalofop, cyhalofap, haloxyfop)
Feynman on Technology
The Technology of GE
• Is very powerful and not, in my opinion, just an
       extension of traditional breeding
• Is imprecise in some ways and scientists could be
       doing a better job of making that clear (see
       www.biotechsalon.com for one scientist’s
       attempt to rectify that situation)
• Can be used to solve agricultural problems
       sustainably, equitably, transparently, etc.
• But GE products can also be unsustainable,
       inequitable, unlabeled, etc.
Conclusions for the Future
• GE could be used to help solve otherwise
      intractable agricultural problems
• GE should not be used to produce
      pharmaceutical products in plants grown for
      food
• GE crops should be mandatorily regulated on
      a case-by-case basis
• All products containing GE proteins should be
      labeled accordingly, especially in a
      democratic, capitalist society like this one

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Genetically Engineered Foods: Past, Present, and Future

  • 1. Genetically Engineered Foods: Past, Present, and Future Sacramento Sustainability Forum November 17, 2011
  • 2. Introduction • First GE Food: Labeled and the GE protein in it regulated as a food additive • GE Foods in the U.S. since: not labeled, GE proteins not considered food additives and not regulated by FDA • GE Products in the Pipeline: Labeling? Regulation? Sustainability?
  • 3. World’s First Genetically Engineered Whole Food MacGregor’sR Tomatoes Grown from Flavr SavrTM Seeds were accompanied by tomato-shaped brochures like this one
  • 4. “Grown From Genetically Modified Seeds” Right on the Sticker
  • 5. Engineered for longer shelf-life and vine-life The gene encoding a softening enzyme in tomato was flipped upside down and backwards and re-inserted into tomato plants, effectively shutting down the enzyme
  • 6. 1-800-34TOMATO in the accompanying brochure For consumers who wanted even more information
  • 7. Use of antibiotic-resistance protein explained Gene isolated from E. coli conferred resistance to the antibiotic kanamycin
  • 8. After the Flavr SavrTM Tomato • No other GE protein (viral, bacterial, etc.) has been regulated as a food additive by FDA • No other GE food has been labeled in grocery stores in the U.S. • No regulation of GE foods (with a couple of exceptions) is required by FDA • Regulation of GE crops by USDA and EPA is only triggered by products containing a “pest” or “pesticide,” respectively
  • 9. Sustainability of Current GE Crops • Resistance to viruses (squash, papaya): reduces use of pesticides • Resistance to insects (corn, cotton, eggplant): reduces use of pesticides but can affect non-target insects • Tolerance of herbicides (corn, soybean): increases use of herbicides and can lead to “super weeds” but can allow low-till and no-till farming
  • 10. Possible Health Issues and GE Products • Resistance to antibiotics (Bt 10) • Inadvertent introduction of allergens (StarLink) • Inadvertent introduction of mutations due to fact that current GE methods are mutagenic • Inadvertent introduction of pharmaceutical proteins into the food supply (pig vaccine)
  • 11. GE Products in the Pipeline • Drought-tolerant corn • Virus-resistant plum • Canola with healthier oil • High-lycine corn (more complete protein) • Crops resistant to additional pesticides (2,4-D, quizalofop, cyhalofap, haloxyfop)
  • 13. The Technology of GE • Is very powerful and not, in my opinion, just an extension of traditional breeding • Is imprecise in some ways and scientists could be doing a better job of making that clear (see www.biotechsalon.com for one scientist’s attempt to rectify that situation) • Can be used to solve agricultural problems sustainably, equitably, transparently, etc. • But GE products can also be unsustainable, inequitable, unlabeled, etc.
  • 14. Conclusions for the Future • GE could be used to help solve otherwise intractable agricultural problems • GE should not be used to produce pharmaceutical products in plants grown for food • GE crops should be mandatorily regulated on a case-by-case basis • All products containing GE proteins should be labeled accordingly, especially in a democratic, capitalist society like this one