1. Steve Provonsha MD MPH

21. Because of resistance, the calories we can’t assimilate, must be disposed of as body fat. Fat cells are the most sensitive cells to insulin. It has to be this way, our bodies have no choice. Resistance Calories Lean Body Mass The Bloodstream Body Fat This is abundantly clear in Cushing’s disease where the cortisol effect is strong enough to cause lean body mass changes like osteoporosis and loss of muscle mass (Cushing’s patients are notoriously weak – cannot do protein synthesis). Yet the cortisol levels are not so much high, as they are elevated to night time (diurnal) levels during the day when the subject eats .

34. pg/ml Glucagon response Richard Gray, Peter Butler, Thomas Beers, Journal of Clinical Endocrinology and Metabolism 81:1508-1511, 1996

36. IGF-1 IGF-1 BP IGF-1 IGF-1 BP Must use protein as fuel. Less for growth. Uses carbs as fuel – more protein for getting bigger. Insulin Insulin

38. Insulin Insulin Insulin EAA’s EAA’s Unrefined Carbs Refined Carbs Amino acids still activate insulin

45. Petersen et al. Pain Stops Exercise Liver Inflammatory Chemistry Lactic Acid Provides Fuel For Sugar Injury Provides Fuel For Shuts Down

54. A Significant Place / A Pivotal Amino Acid 64 base pair combinations for 21 amino acids - duplication Ala A GCU, GCC, GCA, GCG Leu L UUA, UUG, CUU, CUC, CUA, CUG Arg R CGU, CGC, CGA, CGG, AGA, AGG Lys K AAA, AAG Asn N AAU, AAC Met M AUG (start) Asp D GAU, GAC Phe F UUU, UUC Cys C UGU, UGC Pro P CCU, CCC, CCA, CCG Gln Q CAA, CAG Ser S UCU, UCC, UCA, UCG, AGU, AGC Glu E GAA, GAG Thr T ACU, ACC, ACA, ACG Gly G GGU, GGC, GGA, GGG Trp W UGG His H CAU, CAC Tyr Y UAU, UAC Ile I AUU, AUC, AUA Val V GUU, GUC, GUA, GUG Start AUG for Methionine Stop UAG, UGA, UAA

55. Essential Amino Acids

56. Essential Amino Acids

57. Essential Amino Acids

58. Essential Amino Acids

59. Nonfat Milk Human Milk Wheat Soybeans Brazil Nuts Cheddar cheese Almonds Pistachios Pinto Black Salmon Pork Turkey Chicken Beef Egg Cashews Garbanzos Broccoli Tomato Zucchini Whole Milk Don’t forget Methionine and its relationship to Homocysteine