Teresa Sardon / System biology approaches to personalized medicine

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Presentation given by Teresa Sardon from Anaxomics Biotech SL in the framework of the Emergence Forum Barcelona Biocat organized the Barcelona Emergence Forum (April 10-11th, 2014, Congress Palace, Montjuïc) supported by the TRANSBIO SUDOE, a translational cooperation project dedicated to innovation in life sciences in South-West Europe. The Barcelona Emergence Forum contributed to bringing together Academics, Companies, Investment Entities, Technology Platforms and Technology Transfer Offices from Spain, France and Portugal to set up collaborative projects on Human Health & Agro-food Innovation. More information at: http://www.b2match.eu/emergenceforum2014

Saúde Tecnologia Negócios

System Biology Approaches to
Personalized Medicine
© Anaxomics 2014
Teresa Sardon MSc, PhD
Head of BU - Analytical Services

Systems Biology + data from different sources → Mathematical Models
Systems Biology
© Anaxomics 2014
Efficacy and safety
assessment
Molecular and clinical
model
Mechanism of action
Target discovery
Combination therapies
Drug repositioning –
New indications
Biomarkers discovery

© Anaxomics 2014
Shared
characteristics
Clinical data
Omics
• Genomics
• Proteomics
• Transcriptomics
• Metabolomics
…
+ Experimental data
From Systems Biology to Personalized Medicine
Cohort 1 Cohort 2

Responders Non-responders
© Anaxomics 2014
MoA
Biomarkers
Treatment Selection
Case Study: Treatment Responders and Non Responders
MoA Reversion

How do you get it?
© Anaxomics 2014
Consulting Services: Fee for Service
Partnership Agreements:
-Service Platforms
-Research Instituts
-Other companies
CONTACT US:
teresa.sardon@anaxomics.com
info@anaxomics.com
Thanks for your attention!

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1. System Biology Approaches to Personalized Medicine © Anaxomics 2014 Teresa Sardon MSc, PhD Head of BU - Analytical Services

2. Member of eight EU 7th Framework Programme research consortia Finalist in 2011 Red Herring Top 100 Europe 4th place in IMPROVER Challenge 2012 Founded in 2007 – Private capital Based in Barcelona 20 Experts (Pharmacology, Physiology, Artificial Intelligence) Proprietary technology: Therapeutic Performance Mapping System (TPMS) Company Profile Academic Researchers Pharmaceutical companies Nutraceuticals Clinical Researchers CROs Cosmetics Biotechnology companies Venture Capital Veterinary Industry © Anaxomics 2014 OUR CLIENTS: ACHIEVEMENTS: OUR GOAL: “Applying Systems Biology to Health & Life Science to provide solutions to the most challenging biological and medical needs“

3. Systems Biology + data from different sources → Mathematical Models Systems Biology © Anaxomics 2014 Efficacy and safety assessment Molecular and clinical model Mechanism of action Target discovery Combination therapies Drug repositioning – New indications Biomarkers discovery

4. © Anaxomics 2014 Shared characteristics Clinical data Omics • Genomics • Proteomics • Transcriptomics • Metabolomics … + Experimental data From Systems Biology to Personalized Medicine Cohort 1 Cohort 2

5. Responders Non-responders © Anaxomics 2014 MoA Biomarkers Treatment Selection Case Study: Treatment Responders and Non Responders MoA Reversion

6. How do you get it? © Anaxomics 2014 Consulting Services: Fee for Service Partnership Agreements: -Service Platforms -Research Instituts -Other companies CONTACT US: teresa.sardon@anaxomics.com info@anaxomics.com Thanks for your attention!

Teresa Sardon / System biology approaches to personalized medicine

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