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ALCOHOL
ADVERSE EFFECTS OF  ALCOHOL & ROLE OF DISULFIRAM MARIA RUPINI J ROLL NO:46
True or False? Alcohol Slows Down Your Body and Mind.
[object Object],[object Object],[object Object]
True or False? You Feel Alcohol’s Effects Right Away.
[object Object],[object Object],[object Object],[object Object]
 
People who have developed dependence on alcohol are called  ALCOHOLICS .
Alcoholism ,[object Object],[object Object]
Alcohol Dependence ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Blood Alcohol Concentration ,[object Object],[object Object],[object Object]
THE BRAIN
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
 
THE LIVER
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Healthy Liver Alcoholic Liver
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
 
 
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
THE STOMACH
[object Object],[object Object],[object Object],[object Object],[object Object]
 
THE PANCREAS ,[object Object],[object Object],[object Object],[object Object],[object Object],Bleeding Pancreas of an Alcoholic, he’s now dead!
Pyloric  Valve- Spasms in the presence of large amounts of ethanol Small Intestine- Majority of Ethanol absorbed here Damages Mucosal Cells, Villi, and Microvilli Decreases absorption of nutrients and vitamins Increases Triglyceral and Cholesterol production
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],eeew!
BLOOD CHANGES RBC Decreased Production-Anemia WBC Decreased production Decreased response time more infections Increased risk for STD’s/HIV
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Males Damages or kills Leydig Cells Increases feminine characteristics Decreased sexual drive,  reproductive failure, impotence Females Early Menopause Premenstrual discomfort Increased menstrual Flows Infertility
Skeletal Muscle Di srupts internal structure of muscle Cramps, pain, weakness   Alcoholic  Myopathy
FOETAL ALCOHOL SYNDROME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Binge Drinking ,[object Object],[object Object]
Dangers of Binge Drinking ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ALCOHOL TOXICITY ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
WITHDRAWAL SYNDROME ,[object Object],[object Object],[object Object],[object Object]
METHANOL POISONING ,[object Object],METHANOL FORMALDEHYDE FORMIC ACID Aldehyde DH TOXIC EFFECT DUE TO FORMIC ACID
[object Object],[object Object],[object Object],[object Object]
TREATMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
It Kills and Badly Injures
TOO MANY YOUNG LIVES ARE LOST EACH YEAR
 
 
 
 
After a nasty break up she got drunk and went for a drive, with a BAC of .19, missed a turn, flipped and rolled the car more than 5 times.  Fifteen surgeries later she is disfigured and blind with permanent brain damage, luckily she did not hurt or kill anyone else.  Meet Denise Wagoner
 
DISULFIRAM  ,[object Object],[object Object]
[object Object],[object Object],[object Object],ALCOHOL ACETALDEHYDE ACETATE co 2 + H 2 O
[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object]
[object Object],[object Object]
CONTRAINDICATIONS ,[object Object],[object Object],[object Object],[object Object]
DRUGS THAT PPT DISULFIRAM LIKE REACTIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Don’t Live Dangerously
Too Smart To Start
SAFEST AMOUNT OF DRINKS  = 0!!! This is at any age!!!!
THANK YOU

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Alcohol

  • 2. ADVERSE EFFECTS OF ALCOHOL & ROLE OF DISULFIRAM MARIA RUPINI J ROLL NO:46
  • 3. True or False? Alcohol Slows Down Your Body and Mind.
  • 4.
  • 5. True or False? You Feel Alcohol’s Effects Right Away.
  • 6.
  • 7.  
  • 8. People who have developed dependence on alcohol are called ALCOHOLICS .
  • 9.
  • 10.
  • 11.
  • 12.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.  
  • 20.
  • 21.
  • 23.
  • 24.
  • 25.  
  • 26.  
  • 27.
  • 28.
  • 30.
  • 31.  
  • 32.
  • 33. Pyloric Valve- Spasms in the presence of large amounts of ethanol Small Intestine- Majority of Ethanol absorbed here Damages Mucosal Cells, Villi, and Microvilli Decreases absorption of nutrients and vitamins Increases Triglyceral and Cholesterol production
  • 34.
  • 35.
  • 36. BLOOD CHANGES RBC Decreased Production-Anemia WBC Decreased production Decreased response time more infections Increased risk for STD’s/HIV
  • 37.
  • 38. Males Damages or kills Leydig Cells Increases feminine characteristics Decreased sexual drive, reproductive failure, impotence Females Early Menopause Premenstrual discomfort Increased menstrual Flows Infertility
  • 39. Skeletal Muscle Di srupts internal structure of muscle Cramps, pain, weakness  Alcoholic Myopathy
  • 40.
  • 41.  
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.
  • 51.
  • 52. It Kills and Badly Injures
  • 53. TOO MANY YOUNG LIVES ARE LOST EACH YEAR
  • 54.  
  • 55.  
  • 56.  
  • 57.  
  • 58. After a nasty break up she got drunk and went for a drive, with a BAC of .19, missed a turn, flipped and rolled the car more than 5 times. Fifteen surgeries later she is disfigured and blind with permanent brain damage, luckily she did not hurt or kill anyone else. Meet Denise Wagoner
  • 59.  
  • 60.
  • 61.
  • 62.
  • 63.  
  • 64.
  • 65.
  • 66.
  • 67.
  • 69. Too Smart To Start
  • 70. SAFEST AMOUNT OF DRINKS = 0!!! This is at any age!!!!

Notas do Editor

  1. Denise's life changed Feb. 19, 1995. Upset about a dissolving relationship in her life, she had visited her family. She still was upset when she started home and, en route, stopped at a tavern. Each time she emptied her glass, the bartender refilled it. To make matters worse, he seemed to be making advances. His actions only upset her more, so she left. Police said Denise, with a BAC of .19, was going about 40 mph (in a 55-mph zone) when she missed a 90-degree turn in an S-curve and hit a culvert. Her car, a 1989 Ford Escort, went end-over-end three times and barrel-rolled twice before throwing her 70 feet. She landed on her head. A woman at the scene of the accident described Denise's face as "five pounds of hamburger, and the blood bubbling from her mouth was the only evidence she still was alive. She had no nose or upper lip, and her eyes were dangling from their sockets." The 13 trauma doctors who worked on Denise that first night would learn that every bone in her face was broken, except for her bottom jaw. Other injuries included multiple skull fractures, a broken back (in five places), two crushed vertebrae (in her neck), crushed ribs, and a swollen brain. She also had broken shoulder blades, a broken collarbone, a broken left arm (in three places), and a broken right knee. Later, a respirator in the hospital blew out one of her lungs, and the doctors found that her skull was separated from her spine. They didn't think she would live through the next 24 hours, but if she did, they had to find out why she slowly was bleeding to death. She literally had "died" twice from loss of blood. They finally learned she suffered from DIC, a disease that prevents blood from clotting. To repair Denise's lung and some of her other fractures, the doctors had to put her in a medically induced coma for five and a half weeks. They then put seven plates and 22 screws in her head and face, a process that took nearly 18 hours.