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HIV Prevention and Treatment among Latinos in the Southeast USA: Four Studies from a Community-Based Participatory Research Partnership
4 Studies, 1 Partnership ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Grant Sponsors ,[object Object],[object Object],[object Object],[object Object],[object Object]
CBPR Defined ,[object Object]
Our CBPR Partners Include: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Our CBPR Partners Include… ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Setting
Latinos in the US ,[object Object],[object Object],[object Object],[object Object]
Latinos in NC ,[object Object],[object Object]
 
Latinos in NC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hispanics/Latinos in the US have been disproportionately affected by HIV and STDs   ,[object Object],[object Object],[object Object],[object Object]
Southeast and NC ,[object Object],[object Object]
HIV Prevention, Care and Treatment among Latinos ,[object Object],[object Object]
Laying a foundation for reproductive health and HIV prevention among recent immigrant Latinas:  A CBPR approach Rebecca R. Cashman, Scott D. Rhodes, Eugenia Eng, & Florence Simán
[object Object],[object Object],[object Object],[object Object]
Research Partners ,[object Object],[object Object],[object Object]
Background ,[object Object],[object Object],[object Object],[object Object]
Study Purpose / Objectives ,[object Object],[object Object]
Process ,[object Object],[object Object],[object Object],[object Object],[object Object]
Findings from Literature ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intervention Recommendations from Literature Review ,[object Object],[object Object],[object Object],[object Object],[object Object]
Informal Interviews with  Local Providers ,[object Object],[object Object],[object Object]
Provider Recommendations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Provider Recommendations ,[object Object],[object Object],[object Object],[object Object]
Focus Group Methodology  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Excerpted Questions from Moderator’s Guide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Focus Groups with Latinas (N=43) Characteristic Mean or n (%), as appropriate Country of origin Mexico 24 (55.8) Puerto Rico 5 (11.6) El Salvador 4 (9.3) Dominican Republic 3 (7.0) Other 7 (16.3) Years in NC 7 (range 6 months-17 years) High school ed. or below 30 (69.7) Employed 26 (60.5) Living situation Living with male partner 21 (48.8) Reported partner in country of  origin 1 (2.3) Single 13 (30.2) Other  8 (18.6)
Qualitative Themes  ,[object Object],[object Object],[object Object]
Themes, continued ,[object Object],[object Object]
[object Object],[object Object],Themes, continued
Themes, continued ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],Themes, continued
Themes, continued ,[object Object],[object Object],[object Object]
Identified Key Intervention Characteristics ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],A sexual and reproductive health  intervention for Latinas should:
[object Object],[object Object],[object Object],A sexual and reproductive health  intervention for Latinas should:
[object Object],[object Object],[object Object],[object Object],A sexual and reproductive health  intervention for Latinas should:
Curriculum Modules ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Next Steps ,[object Object],[object Object],[object Object]
HIV risk among immigrant Latino gay men and MSM in the rural southern USA:  Findings from a respondent-driven sampling study Thomas P. McCoy,  Scott D. Rhodes, Aaron T. Vissman,  Kenneth C. Hergenrather, Jaime Montaño,  Jorge Alonzo, Mark Wolfson, Cindy Miller, & Fred Bloom
[object Object],[object Object],[object Object],[object Object]
Special thanks to: ,[object Object],[object Object],[object Object]
Background ,[object Object],[object Object],[object Object]
Hard to reach because… ,[object Object],[object Object],[object Object],[object Object]
HOLA: Study Background ,[object Object],[object Object],[object Object],[object Object],[object Object]
Study Goals ,[object Object],[object Object],[object Object]
Condom Use ,[object Object],[object Object],[object Object],[object Object],[object Object]
Study methods: Sampling ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What is RDS? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],RDS requirements:
How do we get the extra RDS data? ,[object Object],[object Object],[object Object],[object Object],[object Object]
What RDS attempts to do… ,[object Object],[object Object],[object Object],[object Object]
HOLA Coupon:
Advantages ,[object Object],[object Object],[object Object]
Advantages ,[object Object],[object Object],[object Object]
Current limitations ,[object Object],[object Object],[object Object]
Current limitations ,[object Object],[object Object],[object Object]
Current limitations ,[object Object],[object Object],[object Object],[object Object]
RDS: The HOLA Study ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
RDS: The HOLA Study ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Data Management and Analysis ,[object Object],[object Object],[object Object]
RDSAT: RDS Analysis Tool Thus, a 95% RDS CI for the population proportion with HIV testing is (57.0%, 78.4%) The point estimate is 72.9% (sample proportion is 68.1%)
Results ,[object Object],[object Object],[object Object],[object Object]
Characteristics of the HOLA study sample (N=190) Characteristic N (%) or Mean ± SD (min-max)  Age (years) 25.5 ± 5.4 (18-48) Country of origin Mexico El Salvador Guatemala 149 (79.2) 3 (1.6) 3 (1.6) Self-identified gender Male Transgender Male to Female 156 (83.4) 31 (16.6) Highest education completed Less than high school diploma High school diploma Some college (no degree) 24 (13.5) 122 (68.5) 23 (12.9)
*n=184; **n=181  Characteristics of the HOLA study sample (N=190) Characteristic N (%) or  Mean ± SD (min-max) Employment Construction Restaurant Factory Furniture manufacturing Hairstylist/barber Janitor/industrial cleaning Animal slaughtering/processing 43 (24.4) 37 (21.0) 21 (11.9) 20 (11.4) 10 (5.7) 8 (4.6) 7 (4.0) Insurance** 42 (22.3) Length of time in NC (years) 6.3 ± 3.5 (0.3 - 22.8) Acculturation  Language use/Ethnic loyalty (   = .92) Media (   = .94) Ethnic social relations (   = .93)  2 (  9.5) 2.1 ± 0.8 (1 - 3.8) 2.5 ± 0.9 (1 - 5) 2.2 ± 0.6 (1 - 3.6) Income < $30,000 150 (82.8) Lives in own house or apartment 65 (34.6)
Selected prevalence estimates Sexual behavior N (Unadjusted %) (95% CI) RDS weighted % (95% CI) Forced to have sex as child or adolescent  6 (3.2%) (1.5, 6.7) 0.9% (not estimable) a Age at first sex with women or men = 16 or less 80 (42.1%) (35.3, 49.2) 45.6% (42.8, 59.3) Multiple male sex partners (2+), past 3 months 124/184 (67.4%) (60.3, 73.7) 88.9% (88.3, 98.3) Inconsistent condom use with men as insertive male partner, past 3 months 50/184 (27.2%) (21.3, 34.0) 33.7% (19.9, 48.2) Inconsistent condom use with men as receptive male partner, past 3 months 51/184 (27.7%) (21.8, 34.6) 34.0% (20.8, 42.3)
Selected prevalence estimates Drug use N (Unadjusted %)   (95% CI)   RDS weighted %   (95% CI)   Marijuana 100 (52.6%) (45.6, 59.6) 56.0% (50.2, 65.8) Alkyl nitrates (poppers)  74 (38.9%) (32.3, 46.0) 36.1% (29.1, 45.3) Cocaine  42 (22.1%) (16.8, 28.5) 27.1% (17.2, 31.6) Non-medical use of needles  25 (13.2%) (9.1, 18.7) 13.6% (9.7, 20.3)
Conclusions ,[object Object],[object Object],[object Object]
HoMBReS-2:  A small group HIV prevention intervention for heterosexual Latino men Scott D. Rhodes,  Aaron T. Vissman, Kenneth C. Hergenrather, Jaime Montaño, Cindy Miller,  Thomas P. McCoy, Eugenia Eng, &  Ralph J. DiClemente
[object Object],[object Object],[object Object],[object Object]
 
HoMBReS-2 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HoMBReS-2: Priorities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HoMBReS-2 Intervention Module Abbreviated Description (1) Introduction to HoMBReS-2 and sexual health Icebreaker: Participants provide Spanish slang for “condom” Enhancing understanding of HIV and STDs globally and within the US and Latino communities Facts about HIV and STDs Overview of intervention (2) Protecting ourselves Mitos y Realidades How to use a condom; Night simulator Video: Angel/Devil;  Modeling the process of bringing up condom use with partner (3) How cultural norms and expectations affect our health Introduction to the influences of cultural norms and expectations on health Activity: Identifying what does it mean to be a man, Latino man, immigrant Latino man, including attitudes towards risk and health seeking behavior.  Activity: Reframing health-compromising norms and expectations about being a man Video:   How to access services ;  Living with HIV (4) Bringing it all together What have we done, learned?
 
Angel deveil pic ,[object Object]
 
Modeling the process of bringing up condom use with partner: Video clip
How to access services:  Video clip
[object Object],[object Object],[object Object],[object Object],[object Object]
Self-Reported Baseline Characteristics  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Self-Reported Baseline Characteristics  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Self-Reported Baseline Characteristics  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Self-Reported Baseline Characteristics  ,[object Object],[object Object],[object Object],[object Object]
Applying Theory of Planned Behavior to explore HAART adherence among HIV-positive Latino immigrants:  Elicitation interview results Aaron T. Vissman,  Scott D. Rhodes, Gabriela Rojas;  Sarah Elizabeth Langdon, Aimee M. Wilkin, &  Kenneth C. Hergenrather
[object Object],[object Object],[object Object],[object Object]
TPB to explore adherence  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The TPB
Step 1 goal: Elicitation interviews identifying beliefs about HAART ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patient-reported barriers and facilitators from the literature ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Barriers identified in research from developing countries ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Elicitation interviews to gain a better understanding of barriers and facilitators to adherence   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Elicitation Interview Guide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Participant Recruitment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Elicitation Interview Analysis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Participants (N=25) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Behavioral Beliefs:  Outcomes of Adherence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Influential Referent Groups  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Influential Referent Group: Family  ,[object Object]
Control Beliefs: Impediments and Facilitators to Adherence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Impediments and Facilitators: Communication with Physician  ,[object Object]
Next steps ,[object Object],[object Object],[object Object]
Long-Term Intervention ,[object Object],[object Object],[object Object]
QUESTIONS?

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Latinas Health Study Partnership

  • 1. HIV Prevention and Treatment among Latinos in the Southeast USA: Four Studies from a Community-Based Participatory Research Partnership
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 8.
  • 9.
  • 10.  
  • 11.
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  • 15. Laying a foundation for reproductive health and HIV prevention among recent immigrant Latinas: A CBPR approach Rebecca R. Cashman, Scott D. Rhodes, Eugenia Eng, & Florence Simán
  • 16.
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  • 20.
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  • 28. Focus Groups with Latinas (N=43) Characteristic Mean or n (%), as appropriate Country of origin Mexico 24 (55.8) Puerto Rico 5 (11.6) El Salvador 4 (9.3) Dominican Republic 3 (7.0) Other 7 (16.3) Years in NC 7 (range 6 months-17 years) High school ed. or below 30 (69.7) Employed 26 (60.5) Living situation Living with male partner 21 (48.8) Reported partner in country of origin 1 (2.3) Single 13 (30.2) Other 8 (18.6)
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41. HIV risk among immigrant Latino gay men and MSM in the rural southern USA: Findings from a respondent-driven sampling study Thomas P. McCoy, Scott D. Rhodes, Aaron T. Vissman, Kenneth C. Hergenrather, Jaime Montaño, Jorge Alonzo, Mark Wolfson, Cindy Miller, & Fred Bloom
  • 42.
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  • 61.
  • 62.
  • 63. RDSAT: RDS Analysis Tool Thus, a 95% RDS CI for the population proportion with HIV testing is (57.0%, 78.4%) The point estimate is 72.9% (sample proportion is 68.1%)
  • 64.
  • 65. Characteristics of the HOLA study sample (N=190) Characteristic N (%) or Mean ± SD (min-max) Age (years) 25.5 ± 5.4 (18-48) Country of origin Mexico El Salvador Guatemala 149 (79.2) 3 (1.6) 3 (1.6) Self-identified gender Male Transgender Male to Female 156 (83.4) 31 (16.6) Highest education completed Less than high school diploma High school diploma Some college (no degree) 24 (13.5) 122 (68.5) 23 (12.9)
  • 66. *n=184; **n=181 Characteristics of the HOLA study sample (N=190) Characteristic N (%) or Mean ± SD (min-max) Employment Construction Restaurant Factory Furniture manufacturing Hairstylist/barber Janitor/industrial cleaning Animal slaughtering/processing 43 (24.4) 37 (21.0) 21 (11.9) 20 (11.4) 10 (5.7) 8 (4.6) 7 (4.0) Insurance** 42 (22.3) Length of time in NC (years) 6.3 ± 3.5 (0.3 - 22.8) Acculturation Language use/Ethnic loyalty (  = .92) Media (  = .94) Ethnic social relations (  = .93) 2 ( 9.5) 2.1 ± 0.8 (1 - 3.8) 2.5 ± 0.9 (1 - 5) 2.2 ± 0.6 (1 - 3.6) Income < $30,000 150 (82.8) Lives in own house or apartment 65 (34.6)
  • 67. Selected prevalence estimates Sexual behavior N (Unadjusted %) (95% CI) RDS weighted % (95% CI) Forced to have sex as child or adolescent 6 (3.2%) (1.5, 6.7) 0.9% (not estimable) a Age at first sex with women or men = 16 or less 80 (42.1%) (35.3, 49.2) 45.6% (42.8, 59.3) Multiple male sex partners (2+), past 3 months 124/184 (67.4%) (60.3, 73.7) 88.9% (88.3, 98.3) Inconsistent condom use with men as insertive male partner, past 3 months 50/184 (27.2%) (21.3, 34.0) 33.7% (19.9, 48.2) Inconsistent condom use with men as receptive male partner, past 3 months 51/184 (27.7%) (21.8, 34.6) 34.0% (20.8, 42.3)
  • 68. Selected prevalence estimates Drug use N (Unadjusted %) (95% CI) RDS weighted % (95% CI) Marijuana 100 (52.6%) (45.6, 59.6) 56.0% (50.2, 65.8) Alkyl nitrates (poppers) 74 (38.9%) (32.3, 46.0) 36.1% (29.1, 45.3) Cocaine 42 (22.1%) (16.8, 28.5) 27.1% (17.2, 31.6) Non-medical use of needles 25 (13.2%) (9.1, 18.7) 13.6% (9.7, 20.3)
  • 69.
  • 70. HoMBReS-2: A small group HIV prevention intervention for heterosexual Latino men Scott D. Rhodes, Aaron T. Vissman, Kenneth C. Hergenrather, Jaime Montaño, Cindy Miller, Thomas P. McCoy, Eugenia Eng, & Ralph J. DiClemente
  • 71.
  • 72.  
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  • 75. HoMBReS-2 Intervention Module Abbreviated Description (1) Introduction to HoMBReS-2 and sexual health Icebreaker: Participants provide Spanish slang for “condom” Enhancing understanding of HIV and STDs globally and within the US and Latino communities Facts about HIV and STDs Overview of intervention (2) Protecting ourselves Mitos y Realidades How to use a condom; Night simulator Video: Angel/Devil; Modeling the process of bringing up condom use with partner (3) How cultural norms and expectations affect our health Introduction to the influences of cultural norms and expectations on health Activity: Identifying what does it mean to be a man, Latino man, immigrant Latino man, including attitudes towards risk and health seeking behavior. Activity: Reframing health-compromising norms and expectations about being a man Video: How to access services ; Living with HIV (4) Bringing it all together What have we done, learned?
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  • 79. Modeling the process of bringing up condom use with partner: Video clip
  • 80. How to access services: Video clip
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  • 86. Applying Theory of Planned Behavior to explore HAART adherence among HIV-positive Latino immigrants: Elicitation interview results Aaron T. Vissman, Scott D. Rhodes, Gabriela Rojas; Sarah Elizabeth Langdon, Aimee M. Wilkin, & Kenneth C. Hergenrather
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  6. Jaime just highlight the gold… quickly!
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  13. Respondent-driven sampling (RDS), combines &amp;quot;snowball sampling&amp;quot; with a mathematical model that weights the sample to compensate for the fact that the sample was collected in a non-random way. Well-connected individuals tend to be over-sampled because many recruitment paths lead to them, so the peer recruitment upon which network-based sampling is based is anything but random. overcomes this dilemma by showing that the breadth of coverage of network-based methods can be combined with the statistical validity of standard probability sampling methods. This model is based on a synthesis and extension of two areas of mathematics, Markov chain theory and biased network theory, which were not a part of the standard tool kit of mathematical sampling theory.
  14. Proportion of condom users (U) = [(P{U recruited by non-U}) * (# of non-U from estimated mean network size (EMNS))] __________________________________________________________________________________ [(P{U recruited by non-U} * (# of non-U from EMNS) + (P{non-U recruited by U}) * (# of U from EMNS)]
  15. TPB elicits participation from the target community, in our case members of the Latino community affected by HV/AIDS, to better understand and characterize factors that influence behavior. The goal is to identify potentially changeable leverage points to increase HAART adherence.
  16. TPB: a person’s behavior is a function of his or her intentions to perform a specific action.
  17. What we know from the literature… Among PLWHA across cultures research has shown adherence to be affected by several common barriers and facilitators. Common barriers: (fear of disclosure, concomitant substance abuse, forgetfulness, suspicions of treatment, regimens that are too complicated, number of pills required, decreased quality of life, work and family responsibilities, falling asleep, and access to medication) and common facilitators (having a sense of self-worth, seeing positive effects of antiretrovirals, accepting their seropositivity, understanding the need for strict adherence, making use of reminder tools, and having a simple regimen)
  18. What we know from the literature… Among developing countries lack of information about antiretroviral therapy (ART), perceived high costs for ART and stigma are also often identified at the population level Long distance from home to the health facility, lack of co-ordination across services, and limited involvement of the community in the programme planning process are additional barriers often identified at the health systems level
  19. Qualitative – Patients were recruited from 2 locations – Infectious Disease Clinic, Wake Forest University School of Medicine and AIDS Care Service in Winston-Salem, NC. ID Clinic nurses sent each week’s clinic schedule to Sarah Langdon, Associate Project Manager, who identified potential participants who were Latino (per race indicated in their chart) and HIV positive (per 042 ICD-9 code, also in their chart). The data collector (Gabriela Rojas) or the APM met with each patient upon their arrival to the clinic to 1) Screen based on immigrant/non immigrant status, and if the patient qualifies, invite them to participate.  Ms. Martha Chica, AIDS Care Service would refer her clients who met the inclusion criteria (Latino, HIV+, immigrant) to the APM. The APM would refer these names/contact information to the data collector who would schedule times to conduct the interviews with the clients at AIDS Care Service. Following completion of interview, participant given an incentive of $40 and interview form/receipt maintained in locked office of APM.
  20. n=28 responses
  21. n=27 responses
  22. Family may be an especially important referent group.
  23. n = 33 responses. Eg. Bipolar disorder: nonadherence identified as an outcome of job placement and a barrier to placement
  24. Enhanced communication to allay fear that ADAP may “go away” and to overcome other impediments such as scheduling.