You are conducting challenging research, and you want to know what it takes to turn the results into innovations that will be successful on the market. You want to include these considerations from the very early stages in order to maximise their impact along your way, and to be able to capitalise on your success in a young enterprise.You are interested in how to construct and capitalise on your personal people network in order to involve experts and future clients and collaborators in the implementation of your ideas as early as possible. This presentation is about : the process of shaping ideas, the creation of learning organisation environments, Risk consideration and mitigation, launching and building the new venture...case example VivaBioCell (Tissue Engineering/Regenerative Medicine).

1. From Medical
Research to Business:
Launching
Great Spin-Offs
Start-up advisor
https://www.linkedin.com/in/sfiligoj
Antonio Sfiligoj

2. This Talk is Based On
• My Experience
• Lean Startup
• Business Model Generation
Authorised and regulated by the Financial Services Authority

3. The Researcher - Entrepreneur
• Researchers are encouraged to take their work out of the lab
and into the commercial sector.
• But trading an experimental design for a contract with a
private firm or launching a start-up is not for everyone.
• learning an entirely new language.
• experience the satisfaction of getting what you have
developed into the hands of the public.

4. The Battelle Way to Innovation
• Federal Grants
• Contract Research / Government
• Contract Research / Single Client
• Contract Research / Multiclient
• IPR Commercialization

5. • Listen !
• Test your hypotheses
• Continuous Discovery
• Done by researchers

6. Customer
Development
Process
Get Out of the Lab !
Researcher - Entrepreneur

7. Some Key Questions

8. 1970 – 1995 Playbook

9. Product Introduction Model:
Two Implicit Assumptions
Customer Problem: known
Product Features: known
Concept/
Seed Round
Product
Dev.
Alpha/Beta
Test
Launch/
1st Ship
The Leading Cause of Startup Death

10. 3 Elements to Innovation:
Market, Technology, Implementation
Innovation
BUSINESS MODEL,
SUPPLY CHAIN,
MANUFACTURING, ETC.
MARKET NEEDS &
APPLICATION5
NEW & OLD SCIENCE & TECHNOLOGY
Eugene Fitzgerald, Andreas Wankerl, Carl Schramm
«Inside Real Innovation»

11. Customer Development
Process

12. CLIENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
CLIENT
SEGMENTS
Search for a Business Model
VALUE
PROPOSITION
COST
STRUCTURE
CLIENT
RELATIONSHIPS
CLIENT
SEGMENTS
KEY
COMPETENCIES
RESOURCES
KEY ACTIVITIES
REVENUE
FLOWS
DISTRIBUTION
CHANNELS
KEY PARTNERS
12
3
4
5
8
6
7
9
Business Model Generation – Alexander Osterwalder, 2010

13. Value Proposition
• Products and services
• Pain Relievers
• Gain Creators

14. How Does This
Really Work?
Here’s how we did it

15. •
•The GMP-in-a-Box does away with expensive
clean room infrastructure and personnel.
• GMP-in-a-Box
Bioreactor
•That’s how we want to make Stem Cells-based therapies
•available to every patient and hospital.
•The automated GMP-in-a-box ensures high quality, high safety, standardization and low cost.

16. GMP-in-a-Box™ platform:
supporting multiple TE
applications
Other
Medical
needs
Osteoarthritis
Bone
Substitutes

17. Unmet market needs:
Osteoarthritis ….!
https://www.youtube.com/watch?v=qm_0PwsOfAU

18. Startups Search,
Companies Execute
Scalable
Startup
Large
Company
Transition
- Business Model found
- Product/Market fit
- Repeatable sales model
- Managers hired
- Cash-flow breakeven
- Profitable
- Rapid scale
- New Senior Mgmt
~ 150 people
The Search
for the Business Model
The Execution
of the Business Model
Early Stage Investors Venture Capital
Corporate Investors

19. Agile Prototyping vs. Engineering
• Agile Development
• Continuous Learning
• Self Organizing Teams
• MVP – Minimum Viable Product
• Regulatory Approvals / Pivots

20. Activating Investors & Partners

21. Closing Thought

22. BACKUP