Learn the importance of hormonal balancing for weight loss.

1. Weight Loss and Your Hormones Afreen Pappa, MD JAVĀNI Med Spa

2. Obesity Crisis US Obesity Rates

3. Obesity Crisis US Obesity Rates

4. Obesity Crisis Texas 28.3% Obesity

5. Why should anyone care? Health consequences of excess weight Heart disease Type 2 Diabetes Breast, uterus and colon cancer High blood pressure High cholesterol Stroke Liver and Gallbladder disease Sleep apnea Arthritis Female problems

6. Why should anyone care? Economic Consequences Significant impact on the health care system Estimated that $51 to 78 billion spent on direct and indirect costs of excess weight in 1998 That number can easily be tripled today

7. Why should you care? Look your best Feel your best Avoid chronic illnesses Increase your quality and quantity of life

8. How did we get here? Traditional medical thinking Caloric imbalance Inactivity Genetics Diseases and medications Actually, there’s more to weight than the above….

9. The Missing Pieces Fad diets Hormonal imbalances Nutritional deficiencies Toxins Brain neurotransmitters Allergies Weight gain is a multi-factorial problem and requires a solution that addresses all problems

10. The Body’s Symphony Hormones/Neurotransmitters Mind Nutrition Body Toxins/Allergies

11. Fad Diets Low fat Low carb AHA diet Mediterranean diet

12. Essential Hormones DHEA Thyroid Insulin Cortisol Estrogen Growth Hormone Progesterone Ghrelin Leptin Testosterone

13. Cortisol Produced by the adrenal glands The only hormone that increases with age Increases with stress Prolonged stress leads to adrenal fatigue (cortisol deficiency)

14. Cortisol Adrenal Fatigue - Cortisol deficient state Cravings for sugar, salt, caffeine, soft drinks Afternoon slump, joint aches, multiple allergies/sensitivities, rashes, psoriasis Frequent illnesses including digestive problems Weight gain in abdomen, insulin resistance, high blood sugar, high blood pressure, insomnia Not recognized by traditional MD’s

15. Chronic Response (adrenal fatigue) Acute Response

16. DHEA One of the fastest declining hormones with age Promotes a sense of well being Affects metabolism of serotonin (a vital brain neurotransmitter) Impaired by hydrogenated fats (margarine)

17. Estrogen Three types of Estrogen Estrone (E1) Produced by ovaries After menopause produced by adrenal glands and fat tissue Levels change in the 40’s and drop sharply in 50’s No specific deficiency symptoms High levels High blood pressure, strokes, heart attack, clots Breast and prostate cancer Shifts fat from hips to abdomen

18. Estrogen Three types of Estrogen Estradiol (E2) Produced by ovaries when not pregnant Levels wax and wane in the 40’s and drop sharply in the 50’s Strongest of estrogens with positive effects on bone, heart and brain health Puts fat on hips which helps with insulin response Deficiency symptoms and conditions Hot flashes, night sweats, insomnia Decreased brain function and dementia Loss of collagen from tissues Headaches Osteoporosis Depression, decreased libido Hypertension

19. Estrogen Three types of Estrogen Estriol (E3) Produced by the placenta during pregnancy Protects from breast cancer Important neurological effects Deficiency symptoms and conditions Vaginal dryness, recurrent urinary tract infections and incontinence Decreased libido Loss of collage from tissues Dementia, Alzheimers, Multiple Sclerosis

20. Gender Benders Estrogen imposters Pesticides BPA Dioxins Chlorine Toxins Cause Weight gain Irregular menstrual cycles Early puberty Increased risk of breast cancer

21. Growth Hormone Peaks around age 12 Builds muscle mass Burns fat Increases with strength training, eating adequate amounts of protein Inhibited by frequent meals Controls insulin Secreted at night and requires proper sleep to work well

22. Ghrelin Produced in the gut Increases appetite Lowered with aerobic activity Disturbed by poor sleep Increased by thinking of food

23. Insulin Produced by the pancreas Allows sugar to be taken up by cells for energy Insulin resistance is the main hormonal abnormality in the US Pre-diabetes Type 2 Diabetes By the age of 35 most individuals have some level of insulin resistance Causes sugar to be taken up by fat cells and stored as fat Deficiency symptoms Weight gain in abdomen, under chin, upper flanks, inner thighs Hypoglycemia

24. Insulin Conditions associated with insulin excess Diabetes Type 2 Heart disease Cancer PCOS Obesity Elevated triglycerides Acne

25. Leptin Produced by fat cells Controls appetite Levels disturbed by refined carbs, sugars and trans fats High levels associated with insulin resistance Improved with Omega-3 fats

26. Progesterone Produced by the ovaries and placenta Levels start to decline in the 30’s Stimulates receptors in the brain, bone formation, uterine lining to support pregnancy Decreases turnover of breast, ovarian and uterine cells – reduces risk of cancer

27. Progesterone Deficiency symptoms Insomnia Anxiety, panic attacks, mood swings, PMS Headache Insulin resistance leading to weight gain Hot flashes Decreased libido Heavier menstrual bleeding Digestive problems

28. Progesterone Deficiency associated conditions Depression and the use of anti-depressants Breast cysts, Fibrocystic breast disease Ovarian cysts Uterine fibroids Infertility, PCOS, Endometriosis Bone loss and Osteoporosis

29. Testosterone Found in men and women Decline begins mid-40’s in women mid-30’s in men earlier with stress and nutritional deficiencies Stimulates and maintains muscle and bone mass while decreasing fat

30. Testosterone Deficiency can cause Decreased libido and sexual function Poor mental functioning Fatigue Loss of confidence Depression/anxiety in men Joint and muscle pain Insulin resistance

31. Testosterone Deficiency associated conditions Bone loss, Osteoporosis Weight gain Dementia, Alzheimers disease Heart disease, stroke High cholesterol Diabetes

32. Thyroid The most important metabolic hormone Decline begins in 40’s or earlier with stress, nutritional deficiencies and exposure to electromagnetic radiation Many processed foods and drugs decrease thyroid activity Bromine, an additive to bread, pastas and all enriched products, sports drinks, & Mountain Dew increases hypothyroidism Affected by fad diets, polyunsaturated oils, nutritional deficiencies, adrenal dysfunction, artificial sweeteners (Splenda)

33. Thyroid Deficiency symptoms Low energy Low mental clarity, memory, focus, concentration Weight gain Depression Hair loss, dry hair and skin Cold intolerance Constipation Elevated bad cholesterol

34. Thyroid Deficiency associated conditions Chronic fatigue syndrome Fibromyalgia Congestive heart failure Osteoporosis Dementia Infertility High cholesterol

35. Essential Hormones DHEA Thyroid Insulin Cortisol Estrogen Growth Hormone Progesterone Ghrelin Leptin Testosterone

36. Fad Diets and Hormones Low fat diet High in sugar Discriminated against good and bad fats Fats & cholesterol are needed for hormone production Adverse effects Increase insulin and insulin resistance, cortisol and leptin Decreases growth hormone, DHEA and sex hormones Hypothyroidism

37. Fad Diets and Hormones Low carb diet High in protein and fat Gout Kidney stones Red meat and processed meats linked to cancer, heart disease Adverse effects Low growth hormone Hypothyroidism Margarine impairs sex hormones and leptin

38. Fad Diets and Hormones Mediterranean diet Carbs from whole grains, vegetables and fruits Protein from beans, poultry and seafood Rich in monounsaturated fat (olive oil and avocadoes) Moderate amounts of alcohol

39. Fad Diets and Hormones Benefits Heart healthy Reduces risk of cancer Risks Alcohol affects hormones Raises insulin and impairs sugar metabolism Lowers testosterone Increases estrogen Affects cortisol Leads to weight gain from empty carbs

40. Countries with Highest Rates of Obesity

41. Hormone Friendly Diet Balanced in all macronutrients Protein Carbohydrates Fat Complex carbs Enough protein to support muscle development Natural fats to support hormone synthesis No processed foods Little to no dairy Organic foods Limited caffeine Limited alcohol Limited meals to boost growth hormone (unless hypoglycemia or diabetes)

42. Hormone Friendly Diet Good Carbs Whole grains Vegetables Fruits Beans Protein Beans Seafood Poultry Limited red meat

43. Hormone Friendly Diet Good fats Monounsaturated Olive oil (cold pressed) Avocadoes Nuts Peanut oil Safflower oil Animal fat Polyunsaturated Omega-3 (Fish oil, flax seed oil) Omega-6 (corn oil, cottonseed oil) in limited amounts 2:1 Omega-3:6

44. Avoid Margarine Soybean oil Food additives Artificial sweeteners High fructose corn syrup MSG Sugar Hydrogenated (trans) fats Hormones

45. Essential Hormones DHEA Thyroid Insulin Cortisol Estrogen Growth Hormone Progesterone Ghrelin Leptin Testosterone

46. The Body’s Symphony Hormones/Neurotransmitters Mind Nutrition Body Toxins/Allergies