7. Secretion of regulatory hormones to control activity of adenohypophysis of pituary gland Production of hormones Control of sympathetic output to suprarenal medullae Suprarenal medulla Preganglionic motor fibers Suprarenal gland Neurohypophysis (posterior lobe) of pituitary gland Adenohypophysis (anterior lobe) of pituitary gland Hormones secreted by adenohypophysis of pituitary gland control other endocrine organs Release of ADH and oxytocin Secretion of epinephrine and norepinephrine HYPOTHALAMUS Endocrine Cells

8. Hormona Reguladora Celulas con receptors para la hormona reguladora Celula responde liberando hormona

10. Glándula pituitaria e hipotálamo

11. Pituitaria = Hipófisis

13. Adenohypophysis (anterior lobe) Neurohypophysis (posterior lobe) Pars intermedia Pars distalis Secretes other pituitary hormones Secretes MSH Releases ADH and oxytocin Anterior and posterior pituitary tissues

14. HYPOTHALAMUS Superior hypophyseal artery Portal veins Inferior hypophyseal artery Hypophyseal veins Capillary beds

15. Arteria Corazon -> Red de Capilares Vena Red de capilares -> Corazon Vasos sanguineos de un Sistema Portal Red de capilares -> Red de capilares

16. Pituitaria=hipofisis Infundibulo Sistema portal hipotal ámico- hipofisiario Capilares fenestrados

17. Supraoptic nuclei Paraventricular nuclei HYPOTHALAMUS MEDIAN EMINENCE Neurosecretory neurons Mamillary body NEUROHYPOPHYSIS OF PITUITARY GLAND Endocrine cells ADENOHYPOPHYSIS OF PITUITARY GLAND Optic chiasm

21. Releasing Hormone (Factor) Pituitary Hormone

25. Hypothalamus Pituitary gland RH Adeno- hypophysis Hormone 1 TRH CRH GnRH TSH ACTH FSH LH Thyroid gland Suprarenal cortex Testes Ovaries Ovaries Testes Gluco- corticoids Inhibin Inhibin Estrogens Estrogens Progestins Androgens Thyroid hormones Negative feedback Hormone 2 Endocrine organ Target cells General pattern KEY Stimulation Inhibition

26. TSH - TRH - Glándula Tiroides

27. CRH - ACTH - Corteza Suprarenal

30. Hypothalamus Pituitary gland RH Adeno- hypophysis Hormone 1 TRH CRH TSH ACTH FSH Thyroid gland Suprarenal cortex Testes Ovaries Gluco- corticoids Inhibin Inhibin Thyroid hormones Negative feedback Hormone 2 Endocrine organ Target cells General pattern KEY Stimulation Inhibition

32. Pattern variations Adeno- hypophysis Adeno- hypophysis Stimulation Inhibition Stimulates mammary Glands Development Milk production PIH PRF PRL GH-IH GH-RH Stimulation Inhibition GH Epithelia, adipose tissue, liver Liver Somatomedins Skeletal muscle, cartilage, and many other tissues KEY Stimulation Inhibition

33. Direct control by Direct release nervous system of hormones Indirect control through release of regulatory hormones KEY TO PITUITARY HORMONES: ACTH TSH GH PRL FSH LH MSH ADH OXT Adrenocorticotropic hormone Thyroid-stimulating hormone Growth hormone Prolactin Follicle-stimulating hormone Luteinizing hormone Melanocyte-stimulating hormone Antidiuretic hormone Oxytocin Kidneys ADH Neurohypophysis of pituitary gland Adenohypophysis of pituitary gland ACTH Suprarenal medulla Suprarenal cortex Suprarenal gland Epinephrine and norepinephrine Somatomedins TSH GH PRL Liver FSH LH MSH OXT Males: Smooth muscle in ductus deferens and prostate gland Thyroid gland Glucocorticoids (cortisol, corticosterone) Bone, muscle, other tissues Mammary glands Testes of male Ovaries of female Melanocytes (melanin disperson) Females: Uterine smooth muscle and mammary glands Thyroid hormones (T 3 , T 4 ) Inhibin Testosterone Estrogen Inhibin Progesterone