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Literature Search and
Synthesis
Alyssa Green, BBA, MLIS
December 21, 2011
Objective


   To find evidence-based
    recommendations for the practice of
    Vitamin D testing.
Method
   Searched numerous databases
    ◦ The Cochrane Library, PubMed, EMBASE,
      AHRQ, Google Scholar and TRIP.
   Used various search techniques
    ◦ Synonyms: Vitamin D, 25-hydroxy-vitamin D,
      25-hydroxyvitamin D, 25-OH D
    ◦ Boolean operators AND, OR, NOT to
      combine terms
    ◦ Truncation to broaden results
   Used backward and forward citation
    linking
Inclusion Criteria
   Evidence-based
    ◦ Systematic reviews, synthesis,
      summaries, clinical guidelines, and
      evidence-based narrative reviews
   Timely
    ◦ Within the last five years
   Critical evaluation
    ◦ Meet JAMA‟s “Users' Guides to Evidence-
      based Medicine” evaluative criteria
Limitations
   Undefined information need

   Literature search had very broad
    scope

   Time constraints

   Working alone on project
Synthesis Overview
   Background
    ◦ Currently a lot of interest in vitamin D
    ◦ Literature divided on its impact on various
      health outcomes
    ◦ No agreement on validity of vitamin D
      deficiency epidemic
   Key findings
    ◦ Agreement that routine testing is
      unnecessary
    ◦ Could be need for testing in certain „high-
      risk‟ populations
Conclusion


   Questions?

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Evidence syntheis presentation

  • 1. Literature Search and Synthesis Alyssa Green, BBA, MLIS December 21, 2011
  • 2. Objective  To find evidence-based recommendations for the practice of Vitamin D testing.
  • 3. Method  Searched numerous databases ◦ The Cochrane Library, PubMed, EMBASE, AHRQ, Google Scholar and TRIP.  Used various search techniques ◦ Synonyms: Vitamin D, 25-hydroxy-vitamin D, 25-hydroxyvitamin D, 25-OH D ◦ Boolean operators AND, OR, NOT to combine terms ◦ Truncation to broaden results  Used backward and forward citation linking
  • 4. Inclusion Criteria  Evidence-based ◦ Systematic reviews, synthesis, summaries, clinical guidelines, and evidence-based narrative reviews  Timely ◦ Within the last five years  Critical evaluation ◦ Meet JAMA‟s “Users' Guides to Evidence- based Medicine” evaluative criteria
  • 5. Limitations  Undefined information need  Literature search had very broad scope  Time constraints  Working alone on project
  • 6. Synthesis Overview  Background ◦ Currently a lot of interest in vitamin D ◦ Literature divided on its impact on various health outcomes ◦ No agreement on validity of vitamin D deficiency epidemic  Key findings ◦ Agreement that routine testing is unnecessary ◦ Could be need for testing in certain „high- risk‟ populations
  • 7. Conclusion  Questions?