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Gigi Au-yeung
- 1. Ensuring healthy lives- Safeguarding your
daily consumption healthiness with fish
technology
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
- 2. Are you aware of your daily
consumption healthiness?
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
Eat
Put
on
Skin
Drink
- 3. Arising safety concerns to
human and environmental
health
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
Water pollution
- 4. Arising safety concerns to
human and environmental
health
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
Infertility Early Puberty Cancer, obesity Intersex species, reduced biodiversity
- 5. Chemicals
added to
everyday
products
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
Pesticides
Vet drugs
Hormones
Antioxidant
s
Preservati
ves
Phthalates
Endocrine
disrupting
chemicals
- 6. Newly created chemicals not being
covered in current regulations or testing
requirement
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
100,000 Chemical and Substance recorded on Substance
Registry Services at USEPA as of 2015
Known problematic chemicals are only “the tip of the iceberg”
-- UNEP & WHO
- 7. Chemical
Testing instrument
For toxicity test • Only test limited targeted/
known/ regulated chemicals/
parameters at a time
• Limited relevance to study
overall in-vivo toxicity of
sample
Cost $ per test but $$$ to cover diff
chemicals
Time T
Ethics -
Control/
standardization
CCC
Sensitivity SSS
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
- 8. in vitro in vivo
Tissues, Cell line,
sub-cellular molecules
in test tube/ lab dish
Animal, multicellular
whole organism
For toxicity test • “2D environment”
• Cellular relevant, part of
whole organism, only
some extent to the overall
in-vivo bio-activity
reflection
• “3D environment”
• Full biological relevance
with systems and
metabolisms, overall
bio-activity reflection
Cost $$ $$$
Time TT TTT Usually months
Ethics Embryonic cells Sacrifice animals
Control/
standardization
CC C
Sensitivity SS S
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
- 9. Animal rights
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
*U.S. Department of Agriculture, Animal and Plant Health
Inspection Service, “Annual Report Animal Usage by Fiscal
Year,” 2 June 2015
Each year, more than 100 million
animals killed in U.S. for our
Science.
- 10. In need of novel
advanced methods
and standards
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
^Reprod Toxicol. 2012 Apr;33(2):128-32. Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life
stages in animal welfare regulations. doi: 10.1016/j.reprotox.2011.06.121. Epub 2011 Jun
Eleutheroembryo stage of fish are not
defined as protected in EU Directive
252010/63/EU^
overall bio-activity reflection
T $ CC SS
not
sacrificing
animals
- 11. © Dr. Gigi Au-yeung | Innovation Director of Vitargent (International) Biotechnology | Hong Kong Science Park |
Vitargent bio-testing solutions
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
- 12. *Wellcome Trust Sanger Institute. "Fishing for solutions: Examining function of all genes in the zebrafish genome to benefit human health." ScienceDaily.
ScienceDaily, 17 April 2013. www.sciencedaily.com/releases/2013/04/130417131722.htm. 70% to human in general, 84% associated with human disease*
# zebrafish researcher, Elisabeth Busch-Nentwich, at the Sanger Institute in Cambridgeshire < https://www.theguardian.com/science/2013/sep/15/zebrafish-human-
genes-project >
Relevant, Effective, Cruelty-free
Higher
numb
er of
offspri
ng at a
time
Geno
me
similar
ity*
a day
in fish
embry
o as a
month
in
huma
n
embry
o #
Trans
parent
, well
studie
d
Effect-
based
Toxicity
Screeni
ng
Verteb
rate
Our fishes
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
- 15. Our vision
Our goal
Our strategy
Safer products for a better world
Create bio toxicity profile for ALL consumer materials & products
To help businesses to improve product safety
Licensing---
In-house
Total Quality
Management
Laboratory
Services +
Consultation
Certification---
Brand building
Our services
Avoid
reputational &
financial risk
Gain public
trust
Stay ahead of
regulation
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
- 17. © Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
First & Only accredited ISO 17025 testing lab in Asia
offering in vivo toxicity screening methods
Among first groups using FET to study potential toxicity on
consumer F&B, skin products
Literature review, Database building and Validation on
thousands of chemicals and products since 2011
- 18. About Vitargent
Hong Kong Science and Technology Park
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
- 19. © Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
Vitargent Scientific Advisory Board
- 20. © Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
Leadership
- 21. © Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
International Collaborative projects
And we welcome you to
join us for the great mission…
- 22. Safer Products, Better World
© Dr. Gigi Au-yeung | Vitargent (International) Biotechnology Limited | Hong Kong Science Park |
www.vitargent.com
