2. WEL COME TO
Taj Mahal
Taj Mahal-One of the seven wonders of the world, One
of the Greatest monuments, dedicated to the memory of
“Queen Mumtaz” who died in child birth, by her
husband “Emperor Sahajahan”, is a testimony and a
grim reminder of the tragedy of maternal mortality, that
can befall any women in childbirth.
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
2
3. Obstetric Haemorrhage
--- Ranks as the First cause of maternal mortality
accounting for 25 – 50 % of maternal deaths
POST ARTUM HAEMORRHAGE
though preventable, accounts for the
majority of the cases of obstetric
haemorrhage, the other causes being
– antepartum haemorrhage, abortion,
ectopic pregnancy and ruptured
uterus.
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
3
4. POST PARTUM HAEMORRHAGE
. . . the most common and severe type of
obstetric haemmorrhage, is an enigma
even to the present day obstetrician as it
is sudden, often unpredicted, assessed
subjectively and can be catastrophic.
The clinical picture changes so rapidly
that unless timely action is taken
maternal death occurs within a short
period.
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
4
5. MAGNITUDE OF THE PROBLEM
Direct Causes (%) of Mat.Mort. in selected countries*
Country
+MMR
Haemorrhage Sepsis
Toxaemia Abortion Obstructed
Labour
INDIA
874
18
14
16
14
03
Bangladesh
600
22
03
19
31
09
Ethiopia
566
6
2
6
25
4
Tanzania
678
18
15
03
17
--
Zambia
118
17
15
20
17
--
USA
15
10
08
17
06
03
*World watch paper 102Jacobson JL ed, 1991
Mar 5, 2014
+MMR – Maternal Mortality Rate / 100000 live births
PPH- Prof.S.N.panda & Dr.A.Patnaik
5
6. MAGNITUDE OF THE PROBLEM
Causes of Mat.Mort. In India
Cause
Reg.Gen. India (1992)
FOGSI (1982)
23.7%
22.3%
Toxaemia
15.2
10.7
Puerperal Sepsis
08.1
28.4
Anaemia
19.4
-
Obstructed Labour
07.1
-
Abortion
11.8
-
Others
14.7
-
Haemorrhage
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
6
7. MAGNITUDE OF THE PROBLEM
CAUSES OF 110 MATERNAL DEATHS AT
OUR HOSPITAL FROM 1/1996-7/2000
120
NUMBER
100
80
11
OTHERS
4
5
7
MALARIA
12
ANAEMIA
60
17
40
23
RUPTURED UERUS
UNSAFE ABORTION
VIAL HEPATIIS
PIH
20
0
Mar 5, 2014
31
HAEMORRHAGE
CAUSES
PPH- Prof.S.N.panda & Dr.A.Patnaik
7
8. MAGNITUDE OF THE PROBLEM
PPH - A world of difference
Year
Developing
Countries
1930
1:3000 Births
Not Available
1950
1:20,000
Not Available
1980
1:60,000
1:1000
2000
Mar 5, 2014
Developed
Countries
1:100,000
1:5000
PPH- Prof.S.N.panda & Dr.A.Patnaik
8
9. POST PARTUM HAEMORRHAGE
DEFINITION: -
Blood loss of 500ml or more per vaginum
during the first 24hrs after the delivery of
the baby.
Risk of Maternal Mortality & Morbidity
are 50 times more after PPH
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
9
10. ASSESSMENT OF BLOOD LOSS
AFTER DELIVERY
Difficult
Mostly Visual estimation (So, Subjective &
Inaccurate)
Underestimation is likely
Clinical picture -Misleading
Our Mothers-Malnourished, Anaemic,
Small built, Less blood volume
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
10
11. MECHANISM OF HAEMOSTASIS
AFTER DELIVERY
• Uterine contraction & retraction
• Platelet aggregation → clot
formation
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
11
13. 1. UTERINE ATONY
RISK FACTORS
Over distension of uterus
Induction of labour
Prolonged / precipitate labour
Anaesthesia (halogeneted) & analgesia
Tocolytics (Tocolytics (also called anti-contraction medications or
labor repressants) are medications used to suppress premature labor )
APH
Grand multiparity
Mismanagement of 3rd stage of Labour
Full bladder
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
13
14. 2. RETAINED PLACENTA
Simple adhesion
Morbid adhesion>Accreta, Increta &
Percreta
3. TRAUMATIC
Large episiotomy & extensions
Tears & lacerations of perineum, vagina
or cervix
Haematoma
Uterine rupture
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
14
16. 4. COAGULATION DISORDERS
Abruptio placentae
Sepsis :IUD,PROM(premature
rupture of membrane)
Massive blood loss
Massive blood transfusion
Severe PET (Pre-eclamptic
Toxemia)/ Eclampsia
Amniotic fluid embolism
Hepatitis
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
16
17. 5. UTERINE INVERSION
←Incomplete InversionFundus felt through the Cx
Complete Inversion with
placenta accreta attached to the
fundus→
Mostly iatrogenic due to
mismanagement of 3rd stage - strong
traction on the cord with a relaxed
uterus / adherent placenta.
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
17
18. SYMPTOMS & SIGNS
Blood loss Systolic BP Signs & Symptoms
(% B Vol)
( mm of Hg)
10-15
Normal
postural hypotension
15-30
slight fall
↑PR, thirst, weakness
30-40
60-80
pallor,oliguria,
confusion
40+
40-60
anuria, air hunger,
coma, death
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
18
19. PREVENTION
Regular ANC
Correction of anaemia
Identification of high risk cases
Delivery in hospital with facility for Emergency
Obstetric Care.
Otherwise transport to the nearest such hospital at
the earliest.
Keep speedy transport available
Local / Regional anaesthesia
ACTIVE MANAGEMENT OF 3RD STAGE OF
LABOUR
4th Stage of labour - Observation, Oxytocin
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
19
20. ACTIVE MANAGEMENT OF 3RD
STAGE OF LABOUR (WHO-1989)
Oxytocics - Routine use in third stage → blood loss ↓
by 30-40%
10 Units Oxytocin IV bolus
Syntometrine 1 Amp IV
Ergometrine 1 Amp IV
Carboprost ( better than Ergometrine) 0.125 – 0.25 Mg IM
Early cord clamping
Controlled cord traction
Inspection of placenta & lower genital tract
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
20
21. MANAGEMENT OF PPH
TEAM- Obstetrician,
Anesthesiologist, Haematologist and
Blood Bank
Correction of hypovolaemia
Ascertain origin of bleeding
Ensure uterine contraction
Surgical management
Management of special situation
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
21
22. MANAGEMENT OF PPH
CORRECTION OF HYPOVOLEMIA
Large bore IV line (two)
Crystalloids (RL)-3ml / ml of
blood loss
Urine output (desired) –30ml / hr
Whole blood / pack cell
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
22
23. MANAGEMENT OF PPH
ENSURE UTERINE CONTRACTION
Palpate fundus
Uterine massage
Bimanual compression
Compression of Aorta against
sacral promontory
Foleys catheters
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
23
24. MANAGEMENT OF PPH
OXYTOCICS
Oxytocin:
Bolus of 10 units IV followed by Continuous
Infusion 100 mu / min
Ergometrine 0.2 - 0.5mg IV
Prostaglandins Carboprost- 0.25mg start, Rpt.15-30 min,
Maximum 2.0mg, Route-IM / intramyometrial
Sulprostone- 400-600 micro gm
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
24
25. MANAGEMENT OF PPH
OTHER MODES
M.A.S.T (Military Anti Shock Treatment)
UTERINE PACKING
UTERINE TAMPONADE
• Large bulb Foleys
• Sangstaken blakemole tube
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
25
26. MANAGEMENT OF PPH
SURGICAL TREATMENT
Depends on
Extent & cause of haemorrhage
General condition of patient
Future reproduction
Experience & skill
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
26
27. MANAGEMENT OF PPH
SURGICAL TREATMENT
Mar 5, 2014
Repair of trauma if any
Uterine Artery ligation
Utero ovarian A. Ligation
Internal Iliac A. Ligation
Brace suturing of Uterus
Hysterectomy
Angiographic embolisation
PPH- Prof.S.N.panda & Dr.A.Patnaik
27
28. MANAGEMENT OF PPH
RETAINED PLACENTA
EUA(examination Under
Anaesthesia & Manual Removal
If Placenta accretaObservation
Cytotoxic drugs- Methotrexate
Hysterectomy
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
28
29. MANAGEMENT OF PPH
ACUTE INVERSION OF UTERUS
Manual replacementUnder GA / Uterine relaxant
Hydrostatic method
Surgical method ( Usually delayed
procedure)
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
29
30. MANAGEMENT OF PPH
MANAGEMENT OF DIC
Fresh blood transfusion
Blood products
Cryoprecipitate
Fresh frozen plasma
Platelet concentrate
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
30
31. MORBIDITY & MORTALITY from PPH
Shock & DIC
Renal Failure
Puerperal sepsis
Lactation failure
Blood transfusion reaction
Thromboembolism
Sheehan’s syndrome
>25% Maternal deaths are due to PPH
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
31
32. Intelligent anticipation, skilled supervision,
prompt detection and effective institution
of therapy can prevent disastrous
consequences of PPH.
Mar 5, 2014
PPH- Prof.S.N.panda & Dr.A.Patnaik
32