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Stages of Mitosis
Alafiya Taher Kapadia
1. Why do cells divide?
2. How do cells divide?
3. Stages of Mitosis
a) Interphase
b) Prophase
c) Metaphase
d) Anaphase
e) Telophase
f) Cytokinesis
Index
Biology is the only subject in which
multiplication is the same thing as division…
You started as a cell smaller than
a period at the end of a sentence…
• Where it all began…
• And now look at you…
How did you
get from there
to here?
 Going from egg to baby….
the original fertilized egg has to divide…
and divide…
and divide…
and divide…
• Getting from there to here…
 For reproduction
 For growth
 from fertilized egg to multi-celled
organism
 For repair & renewal
 replace cells that die from normal wear
& tear or from injury
• Why do cells divide?
•Pop quiz
1.What is the importance of cell division?
Growth
Death
Cancer
Mitosis is the division of somatic cells (body cells)
It is the process in which the nucleus divides to form two new nuclei.
The chromosomal number remains unchanged.
•How do cells divide?
Somatic Cell
Daughter Cells
•Pop quiz
1. Mitosis in body cells results in _____________.
4 daughter
cells
2 daughter
cells
1dupilcate
cell
• The process of mitosis is fast and highly complex. The sequence of
events is divided into stages corresponding to the completion of one
set of activities and the start of the next. These stages in order of
occurrence are-
• Interphase
• Prophase
• Metaphase
• Anaphase
• Telophase
• Cytokinesis
•Stages of Mitosis
•Pop quiz
1. The order of the stages in Mitosis is
Interphase-Anaphase-Telophase-
Prophase-Metaphase
Interphase-Prophase-Metaphase-
Anaphase-Telophase
Interphase-Metaphase-Anaphase-
Prophase-Telophase
• The cell is in Interphase for most of its life cycle.
• In Interphase, the cell “prepares” for division by
• obtaining nutrients and growing,
• copying its DNA, and
• replicating its centrioles.
• The nuclear membrane is still visible.
• Chromatin has not yet condensed into chromosomes in
this stage.
• The nucleolus is still present.
•Interphase
chromatin threads
nucleolus
centrioles
•Pop quiz
1. Body cells are in ________________ stage for most of its life cycle.
Anaphase
Interphase
Prophase
•Pop quiz
1. Body cells are in ________________ stage for most of its life cycle.
Anaphase
Interphase
Prophase
• In Prophase:-
• DNA becomes visible as chromosomes
• Nuclear membrane dissolves
• Centrioles migrate to opposite poles
• Spindle fibers form
•Prophase
chromatids
centrioles
spindle fibers
nucleus
•Pop quiz
1. Spindle fibers form in __________ stage.
Anaphase
Prophase
Metaphase
In Metaphase:-
• Spindle fibers attach to centromeres
• Chromosomes line up at midline of the cell
• This organization helps to ensure that in the next
phase, when the chromosomes are separated, each
new nucleus will receive only one copy of each
chromosome.
•Metaphase
equatorial plane
centromeres
•Pop quiz
1. In Metaphase chromosomes line up along the _________
Equatorial
Plane
Poles
Don’t line up
• In anaphase, the spindle fibres shorten, which splits
the chromosome strand into two separate, sister
chromatids. The sister chromatids are pulled to
opposite ends of the cell.
• This is the only stage in the life of a cell where the
chromosome number is greater than a 2n (or diploid)
count
•Anaphase
sister chromatids
•Pop quiz
1. Only stage where chromosomal number is greater
than 2n is ___________
Metaphase
Anaphase
Telophase
• The chromosomes finally reach opposite poles (the
ends) of the cell.
• The nuclear envelope and nucleolus reform around
each new set of chromosomes. The chromosomes
disperse and are no longer visible.
• Spindle fibers disperse and are no longer visible.
•Telophase
nuclear envelope
cytoplasm
begins to divide
• Cytokinesis marks the end of mitosis in the cell cycle.
It is where the cell officially splits into two separate
cells, called daughter cells. Each daughter cell now
has the same number of chromosomes as the original
cell before mitosis. The cell splits when a furrow forms
that pinches the cell in two.
•Cytokinesis
contractile ring
centrosome
nuclear envelope
decondensed
chromosome
•Pop quiz
1.The chromosome reach the poles of the cell in
___________ stage.
Prophase
Anaphase
Telophase
• Prophase:
• Chromosomes condense
• Nuclear envelope disappears
• centrosomes move to opposite sides of the cell
• Spindle forms and attaches to centromeres on the chromosomes
• Metaphase
• Chromosomes lined up on equator of spindle
• centrosomes at opposite ends of cell
• Anaphase
• Centromeres divide: each 2-chromatid chromosome becomes two 1-chromatid
chromosomes
• Chromosomes pulled to opposite poles by the spindle
• Telophase
• Chromosomes de-condense
• Nuclear envelope reappears
• Cytokinesis: the cytoplasm is divided into 2 cells
Exit
• Summary of Mitosis

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Mitosis

  • 2. 1. Why do cells divide? 2. How do cells divide? 3. Stages of Mitosis a) Interphase b) Prophase c) Metaphase d) Anaphase e) Telophase f) Cytokinesis Index
  • 3. Biology is the only subject in which multiplication is the same thing as division…
  • 4. You started as a cell smaller than a period at the end of a sentence… • Where it all began…
  • 5. • And now look at you… How did you get from there to here?
  • 6.  Going from egg to baby…. the original fertilized egg has to divide… and divide… and divide… and divide… • Getting from there to here…
  • 7.  For reproduction  For growth  from fertilized egg to multi-celled organism  For repair & renewal  replace cells that die from normal wear & tear or from injury • Why do cells divide?
  • 8. •Pop quiz 1.What is the importance of cell division? Growth Death Cancer
  • 9. Mitosis is the division of somatic cells (body cells) It is the process in which the nucleus divides to form two new nuclei. The chromosomal number remains unchanged. •How do cells divide? Somatic Cell Daughter Cells
  • 10. •Pop quiz 1. Mitosis in body cells results in _____________. 4 daughter cells 2 daughter cells 1dupilcate cell
  • 11. • The process of mitosis is fast and highly complex. The sequence of events is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages in order of occurrence are- • Interphase • Prophase • Metaphase • Anaphase • Telophase • Cytokinesis •Stages of Mitosis
  • 12. •Pop quiz 1. The order of the stages in Mitosis is Interphase-Anaphase-Telophase- Prophase-Metaphase Interphase-Prophase-Metaphase- Anaphase-Telophase Interphase-Metaphase-Anaphase- Prophase-Telophase
  • 13. • The cell is in Interphase for most of its life cycle. • In Interphase, the cell “prepares” for division by • obtaining nutrients and growing, • copying its DNA, and • replicating its centrioles. • The nuclear membrane is still visible. • Chromatin has not yet condensed into chromosomes in this stage. • The nucleolus is still present. •Interphase chromatin threads nucleolus centrioles
  • 14. •Pop quiz 1. Body cells are in ________________ stage for most of its life cycle. Anaphase Interphase Prophase
  • 15. •Pop quiz 1. Body cells are in ________________ stage for most of its life cycle. Anaphase Interphase Prophase
  • 16. • In Prophase:- • DNA becomes visible as chromosomes • Nuclear membrane dissolves • Centrioles migrate to opposite poles • Spindle fibers form •Prophase chromatids centrioles spindle fibers nucleus
  • 17. •Pop quiz 1. Spindle fibers form in __________ stage. Anaphase Prophase Metaphase
  • 18. In Metaphase:- • Spindle fibers attach to centromeres • Chromosomes line up at midline of the cell • This organization helps to ensure that in the next phase, when the chromosomes are separated, each new nucleus will receive only one copy of each chromosome. •Metaphase equatorial plane centromeres
  • 19. •Pop quiz 1. In Metaphase chromosomes line up along the _________ Equatorial Plane Poles Don’t line up
  • 20. • In anaphase, the spindle fibres shorten, which splits the chromosome strand into two separate, sister chromatids. The sister chromatids are pulled to opposite ends of the cell. • This is the only stage in the life of a cell where the chromosome number is greater than a 2n (or diploid) count •Anaphase sister chromatids
  • 21. •Pop quiz 1. Only stage where chromosomal number is greater than 2n is ___________ Metaphase Anaphase Telophase
  • 22. • The chromosomes finally reach opposite poles (the ends) of the cell. • The nuclear envelope and nucleolus reform around each new set of chromosomes. The chromosomes disperse and are no longer visible. • Spindle fibers disperse and are no longer visible. •Telophase nuclear envelope cytoplasm begins to divide
  • 23. • Cytokinesis marks the end of mitosis in the cell cycle. It is where the cell officially splits into two separate cells, called daughter cells. Each daughter cell now has the same number of chromosomes as the original cell before mitosis. The cell splits when a furrow forms that pinches the cell in two. •Cytokinesis contractile ring centrosome nuclear envelope decondensed chromosome
  • 24. •Pop quiz 1.The chromosome reach the poles of the cell in ___________ stage. Prophase Anaphase Telophase
  • 25. • Prophase: • Chromosomes condense • Nuclear envelope disappears • centrosomes move to opposite sides of the cell • Spindle forms and attaches to centromeres on the chromosomes • Metaphase • Chromosomes lined up on equator of spindle • centrosomes at opposite ends of cell • Anaphase • Centromeres divide: each 2-chromatid chromosome becomes two 1-chromatid chromosomes • Chromosomes pulled to opposite poles by the spindle • Telophase • Chromosomes de-condense • Nuclear envelope reappears • Cytokinesis: the cytoplasm is divided into 2 cells Exit • Summary of Mitosis