Dr Ajay Kumar Tiwari

b.pharm pharmacy qms pharmaceutical product development pci industrial pharmacy biopharmaceutics pharmacy notes introduction & barriers of drug permeation odds ocular barrier pharm notes pharma notes ocular novel drug delivery system pharmaceutics m.pharm pharmaceutics drug delivery systems m.pharm ocular barriers of drug permeation ocular drug delivery systems pharmaceutical pharma quality management system compartment model pharmacokinetics pharmacokinetic parameters tqm advanced delivery systems two compartment open model one compartment open model pharmacokinetic model mixed order noncompartmental analysis pharmacokinetic models iso glp pharm.d graphical methods third graphical method 2. direct linear plot woolf augustinsson hofstee plot hanes woolf plot lineweaver burk plot michaelis menten equation causes of nonlinearity tests to detect nonlinearity in pharmacokinetics dose dependent pharmacokinetics capacity limited nonlinear nonlinear pharmacokinetics repetitive extravascular dosing repetitive intravenous injections multiple dose regimens principle of superposition drug accumulation t1/2 drug accumulation multiple dosage regimens pbpk physiologically based pharmacokinetic model noncompartmental versus compartmental population a mean dissolution time mean absorption time mean transit time mean residence time statistical moment theory non compartmental analysis nca physiologic pharmacokinetic models non compartmental pharmacokinetics loo riegelman method urinary excretion data method of residuals extravascular administration intravenous infusion intravenous bolus administration multicompartment models hypothetical model mathematical model extravascular iv infusion iv bolus pharmacy syllabus medical pharmacokinetics pharmacokinetic parameter pk model zero order first order order of reaction physiological models pkmodeling change control nabl national accreditation board for testing and cali total quality management quality by design qbd out of specifications oos six sigma concept 6 sigma concept iso 9000 series of quality systems standards iso 9000 iso 14000 good laboratory practice quality management systems