4. From: “ A Potential Decline in Life Expectancy in the United States in the 21st Century” NEJM 2005; 352: 11 What does this say about our present state of health? Why are we witnessing the forecast of a decline in life expectancy in the next generation in the face of being the most medicated society the world has ever seen? - comment by Jeffrey Bland, PhD
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7. From: “ Disease Management and the Organization of Physician Practice” JAMA 2005;293:485-488 “ There is a large gap between what physicians do for patients with chronic diseases and what should be done.” What is the potential benefit of eliminating that gap?
8. From: Chronic Diseases 1 “ Preventing chronic diseases - how many lives can we save?” Lancet 2005; 366: 1578 “ A 2% improvement in the prevention of chronic disease would avert 36 million needless deaths by 2015 with a gain of about 500 million years of life”. What if we just focused on cancer, cardiovascular disease and diabetes?
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10. Health care costs main cause of personal bankruptcy, study finds Feb. 4, 2005 – A study published Wednesday in the policy journal Health Affairs found that approximately half of people in the US who file for bankruptcy cite medical costs as a significant reason for their financial troubles. Based on a survey of 1,771 personal bankruptcy filers, the researchers extrapolated that between 1.9 and 2.2 million people were driven into bankruptcy because of health care costs in 2001 Chronic, mostly preventable disease is the principal cause of death and disability, and consumes 78% of health expenditures… 70% to 90% of deaths from chronic illnesses in the U.S. are believed to be caused by poor nutrition, sedentary living, and tobacco use.
11. From: ACS / ADA / AHA Scientific Statement Preventing Cancer, Cardiovascular Disease, and Diabetes A common Agenda for the American Cancer Society, the American Diabetes Association, and the American Heart Association” Circulation 2004;109:3244-3255 “ In spite of hundreds of medical studies, media reports and advice from health officials, Americans still have not got the message that they can prevent most cases of chronic disease.” – John Seffrin, American Cancer Society CEO
12. From: “ Effectiveness of Therapeutic Lifestyle Changes in Patients With Hypertension, Hyperlipidemia, and/or Hyperglycemia” American Journal of Cardiology 2004;94:1558-1561 “ National clinical guidelines have promulgated therapeutic lifestyle changes as a standard of care in the management of conventional risk factors (for coronary heart disease).”
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15. National Cholesterol Education Program Recommends 12 weeks of “Therapeutic (Wellness) Lifestyle Changes” (TLC) as “first line” treatment for high cholesterol For most patients drugs should be used only if 12 weeks of TLC failed
16. National High Blood Pressure Education Program “ Use (Wellness) lifestyle interventions first, then drug therapy for higher levels of BP or if insufficient response to lifestyle modifications.”
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18. From: “ Effectiveness of Therapeutic (Wellness) Lifestyle Changes in Patients With Hypertension, Hyperlipidemia, and/or Hyperglycemia” American Journal of Cardiology 2004;94:1558-1561 “… the findings clearly show that many patients who have conventional risk factors for coronary heart disease can achieve goal levels without medications within 12 weeks of initiating therapeutic lifestyle changes…”
19. From: “ Effectiveness of Therapeutic Lifestyle Changes in Patients With Hypertension, Hyperlipidemia, and/or Hyperglycemia” American Journal of Cardiology 2004;94:1558-1561 “ Moreover, therapeutic lifestyle changes can generally be implemented less expensively than most medications and, unlike single drug therapy, favorably impacts multiple cardiovascular disease risk factors.”
20. From: ACS / ADA / AHA Scientific Statement Preventing Cancer, Cardiovascular Disease, and Diabetes A common Agenda for the American Cancer Society, the American Diabetes Association, and the American Heart Association Circulation 2004;109:3244-3255 “ At present, preventive health receives only sporadic attention, in the context of office visits for acute and chronic medical problems. Health care providers and medical organizations must transform this model into systems that provide preventive care and early detection as an integral part of standard medical practice .”
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24. From: “ Prevalence of the Metabolic Syndrome Defined by the International Diabetes Federation Among Adults in the U.S.” Diabetes Care 2005;28:2745-2749 “… almost 40% of U.S. adults were classified as having the metabolic syndrome”
25. From: “ Metabolic Syndrome: Time for Action” Am Fam Physician 2004;69:2875-82, 2887-8 “ Soon metabolic syndrome will overtake cigarette smoking as the number one risk factor for heart disease among the U.S. population. The NCEP ATPIII has identified metabolic syndrome as an indication for vigorous lifestyle intervention .”
26. From: “ Metabolic Syndrome: Time for Action” Am Fam Physician 2004;69:2875-82, 2887-8 “ All patients diagnosed with metabolic syndrome should be encouraged to change their diet and exercise habits as primary therapy.”
27. From: “ Metabolic Syndrome in Normal-Weight Americans New definition of the metabolically obese, normal weight individual Diabetes Care 2004;27:2222-2228 “ Individuals in the upper normal-weight and slightly overweight BMI range have a relatively high prevalence and are at increased risk of having the metabolic syndrome. Therefore, screening in individuals with normal or slightly elevated BMI is important in the prevention of diabetes and cardiovascular disease.”
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36. From: “ Effect of a low glycemic index diet with soy protein and phytosterols on CVD risk factors in post- menopausal women ” Nutrition, Feb 2006;22:104-113 This study compared a low glycemic index diet combined with a medical food to the AHA Step I diet in obese, postmenopausal women.
37. Comparing Arms From: “ Effect of a low glycemic index diet with soy protein and phytosterols on CVD risk factors in post- menopausal women ” Nutrition, Feb 2006;22:104-113 -7.8 lbs -14.8 lbs Weight -.5mg/dL +2.8 mg/dL HDL-C +3.2 mg/dL -28 mg/dL LDL-C -2.6 mg/dL -43 mg/dL T-Chol -49 mg/dL -95 mg/dL Triglycerides AHA Step 1 Diet LGI diet with medical food
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39. From: “ Effect of a low glycemic index diet with soy protein and phytosterols on CVD risk factors in post- menopausal women ” Nutrition, Feb 2006;22:104-113 +3% +2.1% 63.2% 61.1% % lean body mass -8% 15 lbs 171 lbs 186 lbs Weight -5%/-8% -6/-7 mmHG 124/77 mmHG 130/84 mmHG Blood Pressure -25% 2.1 mcIU/ml 6.2 mcIU/ml 8.3 mcIU/ml Fasting insulin -34 % -1.7 mg/dl 3.3 mg/dl 5.0 mg/dl hs-CRP -48% 2.2 2.4 4.6 TG/HDL-C -21% 1.2 4.6 5.8 tChol/HDL-C +6% +3 mg/dl 51 mg/dl 48 mg/dl HDL-C -15% -27 mg/dl 158 mg/dl 185 mg/dl LDL-C -16% -43 mg/dl 231 mg/dl 274 mg/dl Total Cholesterol -45% -95 mg/dl 117 mg/dl 212 mg/dl Triglycerides % Change Change After Before
40. From a clinical trial comparing: Healthy Diet or Healthy Diet with a Medical Food Research conducted at the Functional Medicine Research Center Gig Harbor, Washington Medical food with SKRMs: -12.9 lbs, Med Diet: -12.5 lbs, Rimonabant: -11.6 lbs
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42. Ann Fam Med 2005;Vol. 3, Supp 2: p.S4-S11 Healthy behavior produces productive, happy, healthy people!
