16. Causes: Brain Death 25 September 2011 Dr (Brig) YD Singh Normal Cerebral Anoxia
17. Causes: Brain Death 25 September 2011 Dr (Brig) YD Singh Normal Cerebral Haemorrhage
18. Causes: Brain Death 25 September 2011 Dr (Brig) YD Singh Normal Cerebral Trauma
19. Brain Death : Mechanism 25 September 2011 Dr (Brig) YD Singh Neuronal Injury Decreased Intracranial Blood Flow Neuronal Swelling Increased Intracranial Pressure ICP > MAP is incompatible with life
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24. Brain Death Neurologic Examination 25 September 2011 Dr (Brig) YD Singh Pupils dilated with no constriction to bright light
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26. Brain Death Neurologic Examination 25 September 2011 Dr (Brig) YD Singh Occulo-Vestibular Response “ Cold Caloric Testing” Normal Response in Coma No Response in Brain Stem Death
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32. Brain Death Confirmatory Testing 25 September 2011 Dr (Brig) YD Singh Electro-Cerebral Silence Normal EEG
33. Brain Death Confirmatory Testing 25 September 2011 Dr (Brig) YD Singh No Intra- Cranial Flow Normal Cerebral Angiography
34. PET Glucose Metabolism Studies 25 September 2011 Dr (Brig) YD Singh “ Hollow-skull sign” of brain death Cerebral metabolism globally reduced ~50% Normal Nature Rev Neurosci 2005;6:899-909
35. Dynamic Nuclear Brain Scan 25 September 2011 Dr (Brig) YD Singh “ Hollow-skull sign” of brain death NEJM 2001;344:1215-1221