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Food Allergy: Separating
Fact from Fiction
Stephanie Albin Leeds, MD
(Slides adapted from Mount Sinai Jaffe Food Allergy Institute)
March 31, 2016
Topics that will be covered:
-Food Allergy Basics
-Anaphylaxis Basics
-Myths and Facts
Food Allergy Basics
• A food allergy is an abnormal immune response to a food
protein.
• A food allergy results in an activation of the immune system
when a food protein is ingested, leading to the release of
histamine and other mediators to “attack” the food.
• A food allergy presents with allergic symptoms typically
within minutes to hours after ingestion.
• A food allergy can come from almost any food.
Increased Prevalence of Food Allergies
• From 1997 to 2007, the prevalence of reported food allergy increased
18% among children under age 18 years.1
• From 2004 to 2006, there were approximately 9,500 hospital
discharges per year with a diagnosis related to food allergy among
children under age 18 years.1
1. NCHS Data Brief; Food Allergy Among U.S. Children: Trends in Prevalence and Hospitalizations.
http://www.cdc.gov/nchs/data/databriefs/db10.pdf. Accessed February 17, 2016.
Food Allergies Can Be Life-Threatening
• There were about 2500 anaphylaxis-related deaths in the United States
from 1999-2010; most common cause was medication (58.8%), followed by
unspecified (19.3%), venom (15.2%), and food (6.7%)2 – however, food is
most common cause of anaphylaxis in pediatric population.
• It is estimated that up to 150-200 people die each year from food-induced
anaphylaxis.
2. Jerschow E, Lin RY, Scaperotti MM, McGinn AP. Fatal anaphylaxis in the United States, 1999-2010: temporal patterns and demographic
associations. J Allergy Clin Immunol. 2014 Dec;134(6):1318-1328.e7.
Food Allergy Basics
• There is no cure for food allergy– current research is looking
into immunotherapy (oral, sublingual, and epicutaneous), but
there are no FDA approved interventional therapies at this
point.
• Complete and strict avoidance is the only way to prevent a
reaction. Just one bite can cause a reaction.
Myth or Fact
Strawberries are a common cause of life threatening food allergy.
Common Food Allergens
Common Food Allergens by Age
Children
6% affected
Adults
3-4 % affected
Cow’s milk 2.5%
Egg 1.3%
Peanut 1%
Soybean
Wheat
Tree nuts
Fish
Shellfish
Peanut
Tree nuts
Fish
Shellfish
* Fruits and vegetables in
birch-allergic adults (25-75%)
Myth or Fact
If my child has only had hives upon eating peanuts, he does not need
to carry an EpiPen because he will not have a severe allergic reaction to
peanut.
Food Allergy Reactions
• Once a reaction begins, there is no way to know how severe it will
become
• Take all food allergic reactions seriously
• A previous reaction does not predict what your next reaction will be
Symptoms of a Food Allergic Reaction
Cutaneous Manifestations of Food Allergy
Myth or Fact
My egg allergic child with asthma accidentally ate some scrambled egg
and 15 minutes later developed wheezing but no other symptoms. I
should give him an EpiPen.
Anaphylaxis Basics
• Anaphylaxis is a severe, potentially life-threatening allergic reaction
1. Quick onset of hives/ swelling/ flushing
AND AT LEAST ONE OF THE FOLLOWING
• Respiratory symptoms (wheezing, coughing, difficulty breathing)
• Reduced blood pressure/ passing out
2. Two or more affected organ involvement after likely allergen exposure
• Skin (hives/swelling/flushing)
• Respiratory (wheezing/coughing/difficulty breathing)
• Cardiovascular (blood pressure drop)
• Persistent GI symptoms (recurrent vomiting)
3. Low blood pressure after ingesting a known allergen
Anaphylaxis Basics
• Symptoms can being within minutes or up to 2 hours after eating a
food
• For some people, symptoms will begin as soon as the food enters
their mouth, even if they don’t swallow the food
• Anaphylaxis does not result from smelling food- but it has been
reported from inhaling fumes during the cooking of allergen-
containing food
Anaphylaxis Treatment
• Intramuscular epinephrine- EpiPen or Twinject (all Auvi-Qs have been
recalled): PROMPT ADMINISTRATION IS KEY TO SURVIVING ANAPHYLAXIS.
FATALITIES HAVE RESULTED FROM A DELAY/FAILURE TO GIVE EPINEPHRINE.
• Call 911 and follow up in emergency department
• If patient is not improved 3-5 minutes after first epinephrine injection, give
a second injection while waiting for 911 responders
• 4 hour observation period
3 Rs of an Anaphylaxis Plan
•Recognize symptoms early
•React quickly
•Review what caused the reaction
Every school should have a plan for managing allergies!
Myth or Fact
My child has food allergies and it is entirely the school’s responsibility
to make sure that they are safe from allergic reactions at school.
Avoid Accidental Exposure
• Read labels…foods, art supplies, soaps
• Prevent cross contamination in the classroom or lunch room
• Clean hands before and after eating or handling food with soap and
water- hand sanitizers do not remove allergens
• In the classroom, serve allergen free foods first-with clean hands or
clean utensils
• Plan for safe parties/celebrations/field trips
• Prohibit food trading and sharing
Family’s Responsibilities
• Provide written medical documentation
• Provide properly labeled medications and replace after use or
when expired
• Keep emergency contact information up to date
• Teach the child age-appropriate self management skills
• Work with school to develop a plan
School’s Responsibilities
• Create an environment where children, including those with food
allergies, will be safe and included
• Employ prevention and avoidance strategies
• Be prepared to handle an allergic reaction- create a plan
• Address teasing/bullying
Prepare for the Accidental Exposure
• Know the symptoms of an allergic reaction
• Review all emergency procedures and be sure you know when and
how to administer medications
• Keep information about your allergic student someplace where a
substitute will immediately be aware of it
• Test your food allergy plan- have a drill
Resources
The Food Allergy Research and Education
800-929-4040
www.foodallergy.org
The Food Allergy Initiative
212-207-1974
www.faiusa.org
Westchester Health Associates- Allergy and Immunology
1600 Harrison Avenue 281 Garth Road, Suite A
Mamaroneck, NY 10543 Scarsdale, NY 10583
914-777-1179 914-472-3833

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Food Allergy: Separating Fact from Fiction - Westchester Health Pediatrics

  • 1. Food Allergy: Separating Fact from Fiction Stephanie Albin Leeds, MD (Slides adapted from Mount Sinai Jaffe Food Allergy Institute) March 31, 2016
  • 2. Topics that will be covered: -Food Allergy Basics -Anaphylaxis Basics -Myths and Facts
  • 3. Food Allergy Basics • A food allergy is an abnormal immune response to a food protein. • A food allergy results in an activation of the immune system when a food protein is ingested, leading to the release of histamine and other mediators to “attack” the food. • A food allergy presents with allergic symptoms typically within minutes to hours after ingestion. • A food allergy can come from almost any food.
  • 4. Increased Prevalence of Food Allergies • From 1997 to 2007, the prevalence of reported food allergy increased 18% among children under age 18 years.1 • From 2004 to 2006, there were approximately 9,500 hospital discharges per year with a diagnosis related to food allergy among children under age 18 years.1 1. NCHS Data Brief; Food Allergy Among U.S. Children: Trends in Prevalence and Hospitalizations. http://www.cdc.gov/nchs/data/databriefs/db10.pdf. Accessed February 17, 2016.
  • 5. Food Allergies Can Be Life-Threatening • There were about 2500 anaphylaxis-related deaths in the United States from 1999-2010; most common cause was medication (58.8%), followed by unspecified (19.3%), venom (15.2%), and food (6.7%)2 – however, food is most common cause of anaphylaxis in pediatric population. • It is estimated that up to 150-200 people die each year from food-induced anaphylaxis. 2. Jerschow E, Lin RY, Scaperotti MM, McGinn AP. Fatal anaphylaxis in the United States, 1999-2010: temporal patterns and demographic associations. J Allergy Clin Immunol. 2014 Dec;134(6):1318-1328.e7.
  • 6. Food Allergy Basics • There is no cure for food allergy– current research is looking into immunotherapy (oral, sublingual, and epicutaneous), but there are no FDA approved interventional therapies at this point. • Complete and strict avoidance is the only way to prevent a reaction. Just one bite can cause a reaction.
  • 7. Myth or Fact Strawberries are a common cause of life threatening food allergy.
  • 9. Common Food Allergens by Age Children 6% affected Adults 3-4 % affected Cow’s milk 2.5% Egg 1.3% Peanut 1% Soybean Wheat Tree nuts Fish Shellfish Peanut Tree nuts Fish Shellfish * Fruits and vegetables in birch-allergic adults (25-75%)
  • 10. Myth or Fact If my child has only had hives upon eating peanuts, he does not need to carry an EpiPen because he will not have a severe allergic reaction to peanut.
  • 11. Food Allergy Reactions • Once a reaction begins, there is no way to know how severe it will become • Take all food allergic reactions seriously • A previous reaction does not predict what your next reaction will be
  • 12. Symptoms of a Food Allergic Reaction
  • 14. Myth or Fact My egg allergic child with asthma accidentally ate some scrambled egg and 15 minutes later developed wheezing but no other symptoms. I should give him an EpiPen.
  • 15. Anaphylaxis Basics • Anaphylaxis is a severe, potentially life-threatening allergic reaction 1. Quick onset of hives/ swelling/ flushing AND AT LEAST ONE OF THE FOLLOWING • Respiratory symptoms (wheezing, coughing, difficulty breathing) • Reduced blood pressure/ passing out 2. Two or more affected organ involvement after likely allergen exposure • Skin (hives/swelling/flushing) • Respiratory (wheezing/coughing/difficulty breathing) • Cardiovascular (blood pressure drop) • Persistent GI symptoms (recurrent vomiting) 3. Low blood pressure after ingesting a known allergen
  • 16. Anaphylaxis Basics • Symptoms can being within minutes or up to 2 hours after eating a food • For some people, symptoms will begin as soon as the food enters their mouth, even if they don’t swallow the food • Anaphylaxis does not result from smelling food- but it has been reported from inhaling fumes during the cooking of allergen- containing food
  • 17. Anaphylaxis Treatment • Intramuscular epinephrine- EpiPen or Twinject (all Auvi-Qs have been recalled): PROMPT ADMINISTRATION IS KEY TO SURVIVING ANAPHYLAXIS. FATALITIES HAVE RESULTED FROM A DELAY/FAILURE TO GIVE EPINEPHRINE. • Call 911 and follow up in emergency department • If patient is not improved 3-5 minutes after first epinephrine injection, give a second injection while waiting for 911 responders • 4 hour observation period
  • 18.
  • 19. 3 Rs of an Anaphylaxis Plan •Recognize symptoms early •React quickly •Review what caused the reaction Every school should have a plan for managing allergies!
  • 20. Myth or Fact My child has food allergies and it is entirely the school’s responsibility to make sure that they are safe from allergic reactions at school.
  • 21. Avoid Accidental Exposure • Read labels…foods, art supplies, soaps • Prevent cross contamination in the classroom or lunch room • Clean hands before and after eating or handling food with soap and water- hand sanitizers do not remove allergens • In the classroom, serve allergen free foods first-with clean hands or clean utensils • Plan for safe parties/celebrations/field trips • Prohibit food trading and sharing
  • 22. Family’s Responsibilities • Provide written medical documentation • Provide properly labeled medications and replace after use or when expired • Keep emergency contact information up to date • Teach the child age-appropriate self management skills • Work with school to develop a plan
  • 23. School’s Responsibilities • Create an environment where children, including those with food allergies, will be safe and included • Employ prevention and avoidance strategies • Be prepared to handle an allergic reaction- create a plan • Address teasing/bullying
  • 24. Prepare for the Accidental Exposure • Know the symptoms of an allergic reaction • Review all emergency procedures and be sure you know when and how to administer medications • Keep information about your allergic student someplace where a substitute will immediately be aware of it • Test your food allergy plan- have a drill
  • 25. Resources The Food Allergy Research and Education 800-929-4040 www.foodallergy.org The Food Allergy Initiative 212-207-1974 www.faiusa.org Westchester Health Associates- Allergy and Immunology 1600 Harrison Avenue 281 Garth Road, Suite A Mamaroneck, NY 10543 Scarsdale, NY 10583 914-777-1179 914-472-3833