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Wearable technology and blood
pressure monitoring: Making a
dent in global hypertension
© 2019 Valencell, Inc
Ranndy Kellogg, Omron Healthcare
Ryan Kraudel, Valencell
© 2019 Valencell, Inc
Agenda
• Scope of the problem
• A few things to know about blood pressure
• Key challenges in addressing the problem
• Opportunities to address the problem
• Future view of wearables and blood pressure
High blood pressure is a
global health tragedy
Number of people with high blood pressure in 2017
Source: Global, regional, and national comparative risk assessment of 84 behavioural,
environmental and occupational, and metabolic risks or clusters of risks for 195 countries and
territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
https://www.ncbi.nlm.nih.gov/pubmed/30496105?dopt=Abstract
Americans with high blood pressure in 2018
Source: American Heart Association, January 2018
https://www.heart.org/en/news/2018/05/01/more-than-100-
million-americans-have-high-blood-pressure-aha-says
Number of deaths directly attributed to high blood pressure in 2017
Source: Global, regional, and national comparative risk assessment of 84 behavioural,
environmental and occupational, and metabolic risks or clusters of risks for 195 countries and
territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
https://www.ncbi.nlm.nih.gov/pubmed/30496105?dopt=Abstract
Estimated cost of elevated blood pressure around the world
Source: The global cost of nonoptimal blood pressure.
https://www.ncbi.nlm.nih.gov/pubmed/19474763
A few other things to know
about blood pressure
More than smoking, high fasting glucose and high BMI
Source: Global, regional, and national comparative risk assessment of 84 behavioural,
environmental and occupational, and metabolic risks or clusters of risks for 195 countries and
territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
https://www.ncbi.nlm.nih.gov/pubmed/30496105?dopt=Abstract
It’s A Silent Killer
• Time of day
• Food & drink – alcohol, caffeine,
salty foods, etc.
• Exercise
• Temperature
• White lab coat effect
• Medications
• Family history
• Stress
• Full bladder
BP fluctuates at times throughout
the day depending on:
In general, blood pressure
rises as we age…
...but lifestyle choices
have a big influence on
the rate of change.
Challenges in Addressing
Global Hypertension
Source: Resolve to Save Lives
https://www.resolvetosavelives.org/hypertension/
484M 161M 322M 161M
Tracking BP Takes Time
Source: American Heart Association
https://www.heart.org/en/health-topics/high-blood-pressure/understanding-
blood-pressure-readings/monitoring-your-blood-pressure-at-home
• Get a BP cuff
• Learn how to use it
• Use it properly
• Sit still for 5 minutes
• Don’t smoke, drink caffeine or
exercise within 30 minutes the
measure
• Sit correctly
• Measure at the same time every
day
• Take multiple readings & record
the results
• Don’t take measurements over
clothes
• Keep a BP journal
• Time of day
• Food & drink – alcohol, caffeine,
salty foods, etc.
• Exercise
• Temperature
• White lab coat effect
• Medications
• Family history
• Stress
• Full bladder
These confounding factors require
consistency in measurement
Opportunities to Address
Global Hypertension
© 2019 Valencell, Inc
Opportunities
Going from this… To this…
© 2019 Valencell, Inc
Opportunities
Going from this… To this…
Single, point-in-time
measurements
Longitudinal BP monitoring
”in the background” over time
© 2019 Valencell, Inc
Opportunities
Going from this… To this…
Manual tracking
Weaving BP monitoring into
every day life by making it
easier to manage
© 2019 Valencell, Inc
Opportunities
Going from this… To this…
Monolithic recommendations
Personalized insights based on
longitudinal and contextual data
that facilitate focused dialogue and
solutions with doctors/providers
The Future
© 2019 Valencell, Inc
Calibration-Free BP Technologies Are Advancing Rapidly
Technology Maturity
Manual
Cuffs
Automated
Cuffs
Arterial
Line
Optical
PPG-Only
VideoPulse Wave
Velocity
FDA Cleared
High Low
Experimental
Pulse Transit
Time
© 2019 Valencell, Inc
Future View of BP and
Wearables
• Market shifting toward preventative
healthcare, not reactive sick-care
• Combined with:
• Sensors getting more accurate and
ubiquitous
• Applying data science to health data
• Payers aligning incentives and
reducing cost barriers for new
devices/treatments
https://www.marsdd.com/news/transforming-health-shifting-from-reactive-to-proactive-and-predictive-care/
Thank You!

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Wearable technology and blood pressure monitoring: Addressing the global hypertension problem

  • 1. Wearable technology and blood pressure monitoring: Making a dent in global hypertension © 2019 Valencell, Inc Ranndy Kellogg, Omron Healthcare Ryan Kraudel, Valencell
  • 2. © 2019 Valencell, Inc Agenda • Scope of the problem • A few things to know about blood pressure • Key challenges in addressing the problem • Opportunities to address the problem • Future view of wearables and blood pressure
  • 3. High blood pressure is a global health tragedy
  • 4. Number of people with high blood pressure in 2017 Source: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. https://www.ncbi.nlm.nih.gov/pubmed/30496105?dopt=Abstract
  • 5. Americans with high blood pressure in 2018 Source: American Heart Association, January 2018 https://www.heart.org/en/news/2018/05/01/more-than-100- million-americans-have-high-blood-pressure-aha-says
  • 6. Number of deaths directly attributed to high blood pressure in 2017 Source: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. https://www.ncbi.nlm.nih.gov/pubmed/30496105?dopt=Abstract
  • 7. Estimated cost of elevated blood pressure around the world Source: The global cost of nonoptimal blood pressure. https://www.ncbi.nlm.nih.gov/pubmed/19474763
  • 8. A few other things to know about blood pressure
  • 9. More than smoking, high fasting glucose and high BMI Source: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. https://www.ncbi.nlm.nih.gov/pubmed/30496105?dopt=Abstract
  • 10. It’s A Silent Killer
  • 11. • Time of day • Food & drink – alcohol, caffeine, salty foods, etc. • Exercise • Temperature • White lab coat effect • Medications • Family history • Stress • Full bladder BP fluctuates at times throughout the day depending on:
  • 12. In general, blood pressure rises as we age… ...but lifestyle choices have a big influence on the rate of change.
  • 14. Source: Resolve to Save Lives https://www.resolvetosavelives.org/hypertension/ 484M 161M 322M 161M
  • 15. Tracking BP Takes Time Source: American Heart Association https://www.heart.org/en/health-topics/high-blood-pressure/understanding- blood-pressure-readings/monitoring-your-blood-pressure-at-home • Get a BP cuff • Learn how to use it • Use it properly • Sit still for 5 minutes • Don’t smoke, drink caffeine or exercise within 30 minutes the measure • Sit correctly • Measure at the same time every day • Take multiple readings & record the results • Don’t take measurements over clothes • Keep a BP journal
  • 16. • Time of day • Food & drink – alcohol, caffeine, salty foods, etc. • Exercise • Temperature • White lab coat effect • Medications • Family history • Stress • Full bladder These confounding factors require consistency in measurement
  • 18. © 2019 Valencell, Inc Opportunities Going from this… To this…
  • 19. © 2019 Valencell, Inc Opportunities Going from this… To this… Single, point-in-time measurements Longitudinal BP monitoring ”in the background” over time
  • 20. © 2019 Valencell, Inc Opportunities Going from this… To this… Manual tracking Weaving BP monitoring into every day life by making it easier to manage
  • 21. © 2019 Valencell, Inc Opportunities Going from this… To this… Monolithic recommendations Personalized insights based on longitudinal and contextual data that facilitate focused dialogue and solutions with doctors/providers
  • 23. © 2019 Valencell, Inc Calibration-Free BP Technologies Are Advancing Rapidly Technology Maturity Manual Cuffs Automated Cuffs Arterial Line Optical PPG-Only VideoPulse Wave Velocity FDA Cleared High Low Experimental Pulse Transit Time
  • 24. © 2019 Valencell, Inc Future View of BP and Wearables • Market shifting toward preventative healthcare, not reactive sick-care • Combined with: • Sensors getting more accurate and ubiquitous • Applying data science to health data • Payers aligning incentives and reducing cost barriers for new devices/treatments https://www.marsdd.com/news/transforming-health-shifting-from-reactive-to-proactive-and-predictive-care/

Notas do Editor

  1. Ranndy Kellogg - CEO & President, Omron Healthcare
  2. And it’s almost entirely preventable and can be addressed with relatively straightforward actions
  3. This number has doubled over the last 40 years. And it appears to be accelerating – recent study estimated over 1.5B people with hypertension by 2025 - 30-50% growth since 2000.
  4. Also sleep
  5. BP changes over time – not a static measure In general BP rises as we age But lifestyle changes can slow or reverse that gradual BP rise: Physical activity Diet Limit alcohol Don’t smoke Manage stress
  6. Calibrated PTT – no known products on the market. Biobeat does not have approval for calibration-free, even though they referenced the cal-free ISO standard.
  7. Applying data science to enable better outcomes – the combination of biometric data, machine learning and contextual information will drive new insights at individual and population levels.