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Discover the world at Leiden University
Kristina Hettne & Michelle van den Berk FWN 18/04/2019
Let your research bloom:
practical steps for FAIR data
All content is licensed under a Creative Commons Attribution 4.0 Internation
License logo’s excluded and unless specified otherwise in the caption of an
Discover the world at Leiden University
Introduction
Data Sharing and Management
NYU Health Sciences Library
Discover the world at Leiden University
By making your data FAIR
you…
• Create opportunities for sharing and reuse
• Enlarge your exposure
• Enhance your impact
• Show your future employer what you have done
• Avoid issues about verification
• Comply with requirements from funders
Discover the world at Leiden University
FAIR data management
planning
By SangyaPundir – original work, CC BY-SA 4.0,
https://commons.wikimedia.org/w/index.php?curid=53414
062
Location
Organisation
of data
Persistent
identifier
Securit
y
Sustainability
Legal
condition
s
Access
conditions
Software
Documentation
standards
Formats
Provenanc
e
Licens
e
Discover the world at Leiden University
Findable, Accessible, Interoperable and Reusable (FAIR)
Research data needs to:
• Be accessible under clear conditions and licenses
• With clear references
• With rich metadata
Privacy-sensitive data can meet the FAIR principles
https://doi.org/10.1038/sdata.2016.18
Discover the world at Leiden University
https://www.go-fair.org/fair-principles/
Discover the world at Leiden University
https://www.go-fair.org/fair-principles/
Discover the world at Leiden University
https://www.go-fair.org/fair-
principles/
Discover the world at Leiden University
https://www.go-fair.org/fair-
principles/
Discover the world at Leiden University
Example: finding new disease genes
mined from scientific literature
Hettne KM, Thompson M, van Haagen HHHBM, van der Horst E, Kaliyaperumal R, et al. (2016) The Implicitome: A
Resource for Rationalizing Gene-Disease Associations. PLOS ONE 11(2): e0149621.
https://doi.org/10.1371/journal.pone.0149621
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149621
All information in the literature about a gene
All information in the literature about a disease
Overlapping information
=
New evidence for associating a gene with a disease
Thanks to data reuse:
~204.000.000 novel gene-
disease associations
Discover the world at Leiden University
F
A
I
R
Discover the world at Leiden University
RDM and the Research Data Life Cycle Idea
Timeline/plan
Explore data
resources
Data management
plan
Design experiment
Create or
receive
materials
(images, texts,
model,
spreadsheets)
Experiments/
measurements
Add metadata
Validate/clean/deri
ve data
Analyse and
interpret data
Adjust experiment
(re)Run model
Document
Manage and store
Choose license
GDPR: anonymize
Select platform for access
Use persistent identifiers
Describe data
Publish, share and promote
Sustainable
archive
Documentation
Responsibilitie
s
Analyse
findings
Cite correctly
Use, re-use
and promote
http://www.data-archive.ac.uk/create-manage/life-cycle
Discover the world at Leiden University
FAIR and the Research Data Life Cycle
http://www.data-archive.ac.uk/create-manage/life-cycle
Plan for FAIR and well-managed data with a
DMP. Because a DMP is a living document,
ask yourself in each stage of the lifecycle if
there are reasons to update or refine it.
• R1.2: Document what you do
• I1: Implement procedure for
knowledge representation (data
model)
• F2, I2, R1.3: Implement choice of
metadata and data fields
• R1.2: Document what you do
• I1: Follow procedure for knowledge
representation (data model)
• F2, I2, R1.3: Follow choice of
metadata and data fields
• F1, F3, F4, A1, A2, I3, R1:
Deposit data with metadata and
documentation for
interoperability and reusability
with repository • A1.1, A1.2: Define the protocols for access
• R1.1: Define a clear usage license
• The above choices will impact the choice of
repository
• F1: Make sure you cite data with
its persistent identifier
Discover the world at Leiden University
4 steps to make your data
more FAIR
• F: Put your data in a repository
• A: Decide on data access
• I: Describe your data using the metadata
scheme offered by the repository
• R: Choose a license
Discover the world at Leiden University
Maximum Exposure for yourself, your publications and
your data
Data repository
Data journal
Journal article
Discover the world at Leiden University
Centre for Digital Scholarship

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Let your research bloom: practical steps for FAIR data

  • 1. Discover the world at Leiden University Kristina Hettne & Michelle van den Berk FWN 18/04/2019 Let your research bloom: practical steps for FAIR data All content is licensed under a Creative Commons Attribution 4.0 Internation License logo’s excluded and unless specified otherwise in the caption of an
  • 2. Discover the world at Leiden University Introduction Data Sharing and Management NYU Health Sciences Library
  • 3. Discover the world at Leiden University By making your data FAIR you… • Create opportunities for sharing and reuse • Enlarge your exposure • Enhance your impact • Show your future employer what you have done • Avoid issues about verification • Comply with requirements from funders
  • 4. Discover the world at Leiden University FAIR data management planning By SangyaPundir – original work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=53414 062 Location Organisation of data Persistent identifier Securit y Sustainability Legal condition s Access conditions Software Documentation standards Formats Provenanc e Licens e
  • 5. Discover the world at Leiden University Findable, Accessible, Interoperable and Reusable (FAIR) Research data needs to: • Be accessible under clear conditions and licenses • With clear references • With rich metadata Privacy-sensitive data can meet the FAIR principles https://doi.org/10.1038/sdata.2016.18
  • 6. Discover the world at Leiden University https://www.go-fair.org/fair-principles/
  • 7. Discover the world at Leiden University https://www.go-fair.org/fair-principles/
  • 8. Discover the world at Leiden University https://www.go-fair.org/fair- principles/
  • 9. Discover the world at Leiden University https://www.go-fair.org/fair- principles/
  • 10. Discover the world at Leiden University Example: finding new disease genes mined from scientific literature Hettne KM, Thompson M, van Haagen HHHBM, van der Horst E, Kaliyaperumal R, et al. (2016) The Implicitome: A Resource for Rationalizing Gene-Disease Associations. PLOS ONE 11(2): e0149621. https://doi.org/10.1371/journal.pone.0149621 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149621 All information in the literature about a gene All information in the literature about a disease Overlapping information = New evidence for associating a gene with a disease Thanks to data reuse: ~204.000.000 novel gene- disease associations
  • 11. Discover the world at Leiden University F A I R
  • 12. Discover the world at Leiden University RDM and the Research Data Life Cycle Idea Timeline/plan Explore data resources Data management plan Design experiment Create or receive materials (images, texts, model, spreadsheets) Experiments/ measurements Add metadata Validate/clean/deri ve data Analyse and interpret data Adjust experiment (re)Run model Document Manage and store Choose license GDPR: anonymize Select platform for access Use persistent identifiers Describe data Publish, share and promote Sustainable archive Documentation Responsibilitie s Analyse findings Cite correctly Use, re-use and promote http://www.data-archive.ac.uk/create-manage/life-cycle
  • 13. Discover the world at Leiden University FAIR and the Research Data Life Cycle http://www.data-archive.ac.uk/create-manage/life-cycle Plan for FAIR and well-managed data with a DMP. Because a DMP is a living document, ask yourself in each stage of the lifecycle if there are reasons to update or refine it. • R1.2: Document what you do • I1: Implement procedure for knowledge representation (data model) • F2, I2, R1.3: Implement choice of metadata and data fields • R1.2: Document what you do • I1: Follow procedure for knowledge representation (data model) • F2, I2, R1.3: Follow choice of metadata and data fields • F1, F3, F4, A1, A2, I3, R1: Deposit data with metadata and documentation for interoperability and reusability with repository • A1.1, A1.2: Define the protocols for access • R1.1: Define a clear usage license • The above choices will impact the choice of repository • F1: Make sure you cite data with its persistent identifier
  • 14. Discover the world at Leiden University 4 steps to make your data more FAIR • F: Put your data in a repository • A: Decide on data access • I: Describe your data using the metadata scheme offered by the repository • R: Choose a license
  • 15. Discover the world at Leiden University Maximum Exposure for yourself, your publications and your data Data repository Data journal Journal article
  • 16. Discover the world at Leiden University Centre for Digital Scholarship