[Group 9] 1st Year 2nd Semester Kursk State Medical university

1. Kursk State Medical University
Jyoti.
Group- 9.
1st year – 2nd semester.
Teacher-

2. Total bodyCalcium1–1.5 kg
99% in Bones&Teeth
1%in bodyFluidsand tissues

3. -Deficient supply of calcium leads to rickets in children and osteomalacia
in adults.
2- Function The clotting of blood needs calcium ions.
Calcium is known as factor iv in blood coagulation cascade. Calcium ions
act as a cofactor or activator of certain enzymes.
3- By regulating the membrane permeability
Ca++ control the excitability of nerves. If plasma Ca++ level falls markedly,
tetany results in which spasms of various muscle groups occur. Death may
occur from convulsions or from laryngospasm.
1- Function Calcium salts take part in bone and
tooth development .

4. 4-Calcium ions take part in the contraction of muscle
including heart muscle With an increased plasma calcium,
heart stops in systole (calcium rigor)
5-Calcium ions enter through specific channels just as
is the case with cardiac muscle. Drugs which block these channel (Ca++
channel blockers) have profound effect on the contractility of cardiac
and smooth muscles as well as on the conduction of impulses within
the heart. These drugs find use in treatment angina pectoris, cardiac
arrhythmias and hypertension..
6-Calciummediates secretion ofInsulin, parathyroidhormone,
calcitonin, vasopressin,etc.from the cells. It may be used to treat conditions
caused by low calcium levels such as osteoporosis,
osteomalacia/rickets, hypoparathyroidism and tetany. It may also be
used in certain patients to make sure they are getting enough calcium
(e.g., women who are pregnant, and postmenopausal).

5. Thank you