1. How mid-sized players can out-innovate big pharma Bernd Kirschbaum at INSEAD Healthcare Alumni Summit, October 8, 2009
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4. 1. Aggressive R&D productivity goals + high risk projects 2. Not enough resources managing too many projects plus “cutting corners” 3. Quality of projects decline cycle times increase 4. Increasing attrition rates 5. More projects required to meet same goals Large companies have tried to play an unsustainable numbers game Ensure effective portfolio management but use relevant Key Performance Parameters . . . . “ The Vicious Cycle“
5. Stay close to science Avoid misjudgment of technologies based on wishful thinking and/or despair Genomics Era Post-Genomics Era
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7. Constant optimization of a global innovation network Effective use of external scientific and biotech network is essential
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9. Stratified Medicine and Pharma Business – An opportunity for mid-size players Improved benefit / risk ratio Opens doors to new indications Higher & faster market penetration Better price and reimbursement Faster, more directed development Smaller target market Higher R&D costs per applicant Complication through Dx testing in practice Business Outcome + -