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28. February 2018
Zagreb
Croatia
NEW MODERN WAY to APPROACH CANCER:
How to Understand and Treat Cancer with Modern Methods
Speaker: Serge Jurasunas N.D. M.D (h.c) M.D.(Hom)
Professor of Naturopathic Oncology
www.sergejurasunas.com
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Serge Jurasunas N.D.M.D. (Hom)
Pioneer in Natural Medicine and Naturopathic Oncology
Practitioner – Researcher – Author – 50 Years of Practice
Serge Jurasunas N.D.M.D. (Hom)
Pioneer in Natural Medicine and Naturopathic Oncology
Practitioner – Researcher – Author – 50 Years of Practice
Author of 7 books
2017 New book:
Health and Disease Begin in the Colon -
Featuring Professor Serge Jurasunas’
Natural Medicine
www.sergejurasunas.com
Blog:
http://naturopathiconcology.blogspot.com
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New Modern Way to Treat Cancer - Strategic
Immunotherapy, Apoptosis and Angiogenesis
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International Publication of
Articles by Serge Jurasunas
in Various Health Magazines:
 USA
 Germany
 Japan
 Lithuania
 Belgium
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5th International BioBran Workshop, 9-11, June 2017, Krakow, Poland
Oncologist Joseph Brenner M.D., Hegyi Gabriela M.D., Prof.Jurasunas N.D.,
Prof. Tibor Hajto and Immuno-Oncologist Prof.Rupert Handgretinger
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New Modern way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
8
New Modern Way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
9
Excess Red Meat Intake Increases the Risk of
Cancer ( Colon – Breast – Stomach)
Read my book: Health and Diseases Begin in the Colon
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New Modern way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
11
There is an Epidemic of cancer.
1900: 1 person out of 20 gets cancer
1990: 1 person out of 10 gets cancer
1997: (USA) 1 out of every 2 men and 1 out of every 3 women will be diagnosed
with cancer in their lifetime, soon will be 1 in two women and the statistics seem
to be darker for the future.
The world health Organization (WHO) reported that the cancer prognostic for
2020 will INCREASE between 50-100% in the number of the sick and for deaths.
Every minute in the US a cancer patient is dying form Cancer: 60 per hour, 1440
per day or 43200 per month. Over half million per year.
CHILDREN: Every year the number of children dying of cancer grows.
2 out of 3 US cancer patients die before the 5 year survival mark, undergoing
conventional treatment.
What can be done about this ?
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New Modern Way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
13
New Modern way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
Angiogenesis: DNA Mutation Begins After
Radiation Exposure –Red Tissues Show
Inflammation
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Tumor Immunology & Immunotherapy
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New Modern way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
17
New Modern Way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
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New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
Cancer is like a Monster with Several Heads.
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Cancer cannot be attacked only in one direction,
but several directions at the same time.
You need more than one arrow to kill the tumor.
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 Many cancer and pre-malignant forms are hard to detect or are
asymptomatic for many years
 Conventional diagnostics are inefficient in cancer prevention
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Declaration signed December
23th, 1971 with the promise to
have cancer cured within the
next 5 years. Since, nearly $ 300
billion has been spent with no
cure yet!!!
1971 Declaration of War on Cancer by US
President Richard M. Nixon signing the National
Cancer Act
Where are We Today with Cancer ?
Despite the progress in
Oncology and some benefit in
the gold standard of palliative
therapy, surgery and radiation,
conventional treatment has not
achieved the hope and
expectation to cure cancer.
In metastasic Cancer:
Oncology is not better than 30
years ago. There has been no
significant change in the
survival rate.
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New Modern way to Treat :ancer, Strategic,
Immunotherapy, Apoptosis and Angiogenesis
Problems of Conventional Oncology
→ Chemotherapy is toxic, induces adverse
effects and can be fatal to patients
→ Resistance of cancer to chemo-radiation
→ Induces adverse effects including death
→ Many anticancer drugs show little or no
efficacy
→ Chemotherapy and radiation is carcinogenic by
itself responsible for second cancer
→ Metastasis cancer is incurable and responsible
for 95% of deaths
→ Recurrence is sƟll too high
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Cytotoxic Chemotherapy
o More chemotherapy is more toxic, but not necessarily
more effective
o Chemotherapies are selected empirically
o After 6 months chemotherapy loss effectiveness
o Chemotherapy does not kill cancer stem cells
Removing a tumor by surgery is like removing a
large patch of weeds in your garden's soul. You
leave some weed roots behind that grow again, the
same as with a tumor and metastasis.
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Cancer cells are like weeds in your garden,
you spray them directly with toxic insecticides and kill
not only the weeds but the good plants as well, then
your soil becomes depleted and sick.
29
New Modern Way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
30
New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
31
New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Cancer is a Disease of the Cell Cycle
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New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
Over 60 000 papers
Called ‘The Garden of our
Genome’
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New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
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New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
37
New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
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New Modern way to Approach Cancer: Strategic Immunotherapy,
Apoptosis and Angiogenesis.
Growth of Xenograft Tumors
Tumors with an intact
p53 gene regressed
during the treatment,
whereas the tumors
with defective p53
genes continued to
grow.
40
41
P-53 Tumor Suppressed Gene:
Understanding P53 based Anticancer
Therapies utilizing Dietary Agents
By Serge Jurasunas
Published in Townsend Letter, The Examiner of
Alternative Medicine USA ( August/Sept 2015
42
New Modern way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
Video from Researcher , Dr. Marc Diederich
from the University of Singapore
(From My Science Work)
A number of recent articles published in various countries have
shown that reactivating the immune system to treat cancer is now
attracting oncology theroists.
43
Reactivating the Immune System Against Cancer: A Role for Natural Compounds
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New Modern way to Treat Cancer: Strategic,
Immunotherapy, Apoptosis and Angiogenesis
45
Are we nearing a cure for cancer? The Holy Grail is
closer than ever, oncologist claims.
Dr. Rebecca Kristeleit of University College London, Hospital, said advances in a
revolutionary treatment called Immunotherapy were now
occurring at a rapid rate…
We are beginning to start thinking about using the word cure.
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Biobran/Mgn3
The BREAKTHROUGH in Immuno-Oncology
Two decades of studies show that Biobran/Mgn3, a
natural compound made from modified rice bran is a
potent immunomodulator of NK cells, our most
important line of defense against cancer including T-
cells, B-cells and global immune system function.
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Dietary fibers are eliminated by the intestine but Biobran is absorbed in the
small intestine practically undigested entering into the blood to become a
nutritional food that activates N.K.cells and optimizes immune function when
taken orally.
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
49
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Biobran increases the Curve of NK Cells
If you prescribe 2g of
Biobran to volunteers then
you can see a curve of NK
cells increasing about 60%
after two weeks. But if you
continue, you can achieve
up to 200 even 300% or
more NK cell number and
activity.
NK cells are here but not
activated to release their
toxic enzymes (perforin)
through the membrane of
cancer cells.
Ghoneum M. “Enhancement of Human natural killer cells activity by modified
arabinoxylan from rice bran. (Mgn3) Int. Immunotherapy 1998. XIV.89-99
50
- Cancer patients on chemotherapy have a depressed NK cell
activity attributed to a decrease or absence of perforin and
granzyme (1).
- Mgn3 Biobran studies have shown that the treatment causes
an increase in the granular content (perforin and granzymes)
of NK cells.
- It also results in an increased NK cell binding capacity to
cancer cells.
(1) Culler S.P. Brunet M., Martin S.J. – Ganzymes in cancer and immunity – Cell Death Differ.
2010.17-616-623
51
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
52
Treatment with BioBran causes a remarkable increase in NK cells activity
in various cancer after 2 weeks.
PERCENTAGE OF INDUCTION
Breast cancer = 154 -332%
Leukemia = 100-240%
Cervical cancer = 100-275%
Prostate = 174-385%
Multiple Myeloma = 100-537%
Enhancement of NK cells activity continue to rise at 3-6 months
after treatment. (1)
(1) Ghoneum M. Narmatalla G. N.K Immunomodulatory function in 27 cancer patients by Mgn3, a modified arabinoxylan from rice bran.
(2) The abstract of 87th Annual Meeting of the American Assn. for cancer Research. Wash. D.C April 20-24.1996.
53
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
NK cell attacking cancer cell after being activated with the
natural compound Rice Bran Arabinoxylan Compound
One Activated NK Cell Attacking 3 Cancer
Cells
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Biobran Enhances the Effect of Chemotherapy Leading to Effective
Treatment at Low Dosage with Less Toxic Effect and More Results
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Some of Our Clients Have Been Taking Biobran on Long-Term Follow
Up from 2-4-7 Years Without Toxicity
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
NK Cell Activity Increases Survival of Cancer Patients.
In different types of human tumors including
melanoma, breast cancer, bladder, colon, prostate,
ovary, rectum, glioblastoma; longer survival has been
observed in patients with a higher number of
lymphocytes and NK cells.
References: Jass J.R. Lymphocytic infiltration and survival in rectal cancer J.Clin.Pathol. 1986-19-585-589
Clemente CG et al. Prognosis value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous
melanoma. Cancer. 1996 – 77 -1303-1310
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
BIOBRAN (MGN-3 arabinoxylan compound).
CONCLUSION:
In human studies BioBran has been shown to be the most
effective in activating NK cells and optimizing immune
function when taken orally before or after meals.
CURCUMIN – A Potent Anticancer Agent
(Yellow ingredient derived from curcuma longa.l one of the most
extensively investigated phytochemical compounds with ANTICANCER
properties. (1)
(1) Anticancer potential of curcuma. An old spice with new targets. Bharat B. Aggarwal Ph.D. University of
Texas M.D. Anderson Cancer Center. Houston. TX.USA
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Human Melanoma Cell Line SK-MEL-37 Cells have been Treatd with 15uM
and 20uM of Curcumin for 24 hours: (B and D) Entering into Apoptosis. (A
and C UnTreatd Cells).
These cells have demonstrated to be resistant to doxorubicin, cisplatin in
culture but sensitive to curcumin treatment.
Marcella Lemos Carneiro – Morphological alterations and Go/G1 cell cycle arrest induced by curcumin in human SK-
MEL-37 melanoma cells. Braz.arch.Biol. Technol.Vol.53 n.2.Curitiba.April.2010
Curcumin potentializes the
effectiveness of
chemotherapy in a variety of
cancers including breast,
ovarian, colon and pancreatic
and could become a
promising tool.
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Curcumin Increases the Sensitivity of Drug Treatment in
Breast, Ovarian, Cervical, Pancreas and Colon Cancer
- 5 Fu
- Taxol
- Pactitaxel
- Cisplatin
- Adramycin
- Daunorubicin
Koo J.Y. et al, 2002, VBS et al. 2003, Chan M.M., 2003, Chuang S.E. et al, 2002
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
A Study in Breast Cancer
(Bayet-Robert and Collegues 2010)
Oral curcumin and docetaxel administered to
INOPERABLE breast cancer patients with advanced
tumors and metastasis, became OPERABLE after the
combination therapy.
Patients had LOWERED tumor MARKERS and V.E.G.F.
levels indicating REDUCED cancer cell SURVIVAL and
ANGIOGENESIS, tumor SIZE and inflammation. (1)
(1) Serge Jurasunas – Complementary Approach to Breast Cancer. A Case with Multiple Liver
Metastasis is Free from Disease. Townsend Letter August/September 2015.
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Synergetic Effect of Biobran MGn3 and Curcumin
in Cancer Treatment with Chemotherapy
- Faster reduction and/or elimination of secondary
nodules in cancer recurrence.
-Significant reduction of large tumors when
taken together with chemotherapy.
- Advanced cancers with multiple metastasis
(Liver, lung, etc.), having received poor
prognosis with a combination of chemotherapy,
has resulted in prolongation of lifespan (6-8
years) with maintenance, along with an improved
quality of life (QOL). 66
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
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Microbiome:
A new target in Immuno-oncology.
Stronger immune response to kill cancer cells.
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
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Distribution and abundance of bacteria in human
gastro-intestinal tract
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TOP KNOWN BENEFITS OF HUMAN MICROBIOME
(Commensals bacteria)
 Preventing infection by pathogens bacteria
 Development of the immune system
 Digestion of food
 Vitamins production ( B2, B12, K, Folic acid
 Toxin degradation
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
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Foods That Balance the Gut Microbiome
> Fibers > Kefir
> Vegetables > Miso
> Fruits
> Probiotics supplementation
> Fermented food
> Lacto-fermented Vegetable Juice
> Buttermilk > Pickles > Natto
> Apple Cider Vinegar
> Kombucha > Fermented Cabbage
AVOID STRESS DURING MEALS!
See my article: “Can Food Prevent and be Efficient in Cancer
Treatment”, fully illustrated.
www.slideshare.net/sheldonstein
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Protocol for Cancer Patients:
Biobran, 1 bag of 1gr 3 times per day, 20 min. after meal.
Curcumin, 1 bag of 1500 mg liquid diluted in water to take 3 times per day
between meal.
Alpha lipoic Acid, 300 – 400 mg per day.
Additionally as a support to nutritional needs: Detoxification,
boosting mitochondria function and to activate ATP energy and reduce tumor
aggressivity.
Enzyme Yeast Cells (Zell-Oxygen)
See my diet paper: “Can Food Diet Prevent and Be Efficient in Cancer Treatment”
Available on my blog: www.Naturopaticoncology.blogspot.com
What I Should Eat Now !
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New Modern Way to Approach Cancer:
Strategic Immunotherapy, Apoptosis and Angiogenesis
Prevention
During cancer treatment only YOU can make the
Choice and dedice which road to take.
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Food is Powerful Medicine
“Three times a day, day after day, we are eating natural foods that can
influence our GENES and help us to PREVENT and FIGHT CANCER”
- Prof. Serge Jurasunas ( N.D. M/D.(h.c)
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A Few Interesting Case Histories
We Don’t Cure All the Cancers but…
-Many cases after 25-30 years are alive and doing well.
-Several have had a 10 year extension.
-Several advanced cases have improved their quality of life with a life
spent up to 7 years , including prostate cancer, multiple myeloma,
breast cancer and pancreatic cancer.
-Unfortunately many cases come in too late that end up as fatalities
from excess chemotherapy.
-Overall our treatments have demonstrated efficacy, help the patient
by reducing toxic effects, improve chemotherapy effectiveness,
quality of life and increase life expectancy.
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The Toxic Effects of Chemotherapy
Female:
Breast cancer patient suffering from
strong adverse effects from
chemotherapy. Paralyzed from a
peripheral Neuropathy.
82
Improving Patient Quality of Life, Less Adverse
Effects and Increasing Chemotherapy Effectiveness
F. 71 year old- Breast Cancer –
Chemotherapy with severe toxic adverse
Effects-
Developed a peripheral neuropathy –
Paralyzed on the first consulation.
F. 44 year old- Breast Cancer –
With multiple metastasis to liver –
Follows our treatment during
Chemotherapy remission
CASE published in Townsend Letter
August/September 2015
F.41 years – Asympthomatic Prime Lesions 18 cm –
Secondary Lesions 8 cm
Combination of chemotherapy with our complementary treatment that
targets apoptosis, angiogenesis, immune activity – Anticancer Diet
83
Advanced Gastric Cancer - Results of Blood Analysis
July 2015 April 2015 July 2015 April 2015
Lesion of
30,1 mm
Lesion of
48,7 mm
Lesion of
18 cm
p53 Gene Expression
p53 Protein Level
mutated
p53 Protein Level
normal
58 units/µl of plasma
35,4 units/µl of plasma
1 unit/µl of plasma
72,4 units/µl of plasma
Reference range:
10-50 units/µl of plasma
Reference range:
0,10 – 1,00 units/µl of plasma
Reference range:
5 - 15 units
Tumor Marker 2 – Pyruvate Kinase
TM2.PK
Advanced Gastric Cancer - Result of Blood Analysis
1st Test: 28/04/2015 2nd Test: 26/06/2015
p53 Gene Expression
223 units/µl of plasma
p53 Protein Level n
normal
4 units/µl of plasma
p53 Protein Level
mutated
Not detectable
23,8 units/µl of plasma
Tumor Marker 2 – Pyruvate Kinase
TM2.PK
Comment: We significantly increased about 4 times the expression of p53 gene and increased
only to a certain extent normal p53 protein. We reversed the production of mutant protein to
normal wild type. TM2.PK activity decreased to an almost normal range.
After the applied therapy
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Advanced Gastric Cancer - Photo taken on May, 2017
86
Breast Cancer with Multiple Metastasis to Liver
Complete Case Published in the Townsend Letter August/Sept 2014 or
online at www.sergejurasunas.com
Patient female, 44 years old diagnosed in October 2011 with a stage III left breast
cancer, with dissemination of about 30 lesions to the liver; up to 1,5cm size for many
localized in the left lobe, and segment III and IV of the right lobe.
Breast tumor was about 3.5cm with inflammation spread to neighboring tissues; many
swollen lymph nodes were diagnosed on the left part of the neck. Chemotherapy was
suggested before surgery to reduce the tumor and the inflammation.
January 2012 – The patient came into our clinic suffering from adverse side effects
having had very little response from chemotherapy. She felt tired, nausea, loss of
appetite, anxiety. We had taken 3 different tests: Live Blood Analysis, Oxidative Dried
Blood Test and Molecular Markers Testing. These tests showed very high BCL2
activity, low BAX gene activity and especially very high VEGF levels showing activated
angiogenesis in the solid tumor.
Treatment – L.C.E., Biobran MGN-3, Curcumin and Anticancer Diet
After 2 months of treatment the inflammation was almost gone, in the same way as
the swallowed ganglions and reduced tumor. Surgery was done followed by
chemotherapy and our treatment. In 2003 a new scan showed total elimination of the
30 liver nodules and complete remission. In 2017 the patient was still in remission but
still comes in regularly for our check up exams.
87
THE ANTI-TUMOUR EFFECTS OF THE APPLIED TREATMENT
02/12/12370 05/12/12461
Ref. Range
p53 gene expression 200 427 10-50 units/ul of plasma
p53 level mutated ND ND ND units/ml of plasma
p53 level wild ND 0,4 0.10-1.00 units/ml of
plasma
Bcl-2 gene expression 8000 796 <10 units/ul of plasma
Bax gene expression 167 1543 10-100 units/ul of plasma
Bcl-2/Bax ratio 0.02 1.93
Surviving gene expression 171 900 <10 units/ul of plasma
P21 gene expression 139 738 10-50 units/ul of plasma
Surviving/p21 ratio 0.8 0.8
VegF gene expression 2353 ND 10-100 units/ul of plasma
A Complementary Approach to Breast Cancer: A Case with Multiple Liver
Metastasis is Free from Disease
Complete Report – Townsend Letter Magazine – August/Sept 2014
Breast Cancer with Multiple Metastasis to the Liver
88
Breast Carcinoma Stage IV with Multiple Metastasis to Ganglions,
Liver, Bone, Pleura and One Nodule to Right Lung
Patient female – 42 years old – Breast carcinoma stage IV with multiple metastasis
to ganglions, liver, bone, pleura and one nodule to right lung.
The patient underwent a radical mastectomy and started chemotherapy on October
2015. A February, 2016 scan showed more dissemination of metastasis, which
increased in April, with poor physical condition. There was strong resistance from
cancer cells to chemotherapy with more dissemination of metastasis.
The patient came to us in May 2016 and immediatly started our treatment.
Biobran MGN-3, 3 gr per day – Curcumin, 4,5 gr per day – Enzyme yeast cells
preparation, 40 ml per day – Coenzyme Q10, 300 mg per day followed by an
aggressive anticancer diet and plenty of vegetable juices which is important in any
cancer treatment.
August 2016, a new scan showed major improvement, about a 70% reduction in nodule
size, demonstrating synergy with our combination therapy with chemotherapy by
increasing effectiveness by targeting apoptosis, angiogenesis and immune cell activity.
Results in the next slide reveal the patient got worse from chemotherapy alone, but after 3
months had a much better scan after our complementary therapy.
89
Advanced Prostate Cancer (1)
Patient male – 71 years old – Advanced prostate cancer.
The patient was diagnosed in 2005 with a prostate cancer with
dessimination of bone metastasis. Very high PSA 1.260 ng/ml. No surgery,
chemotherapy or radiation was suggested but only a hormonal therapy,
but without result. The patient was in a very bad condition.
2006 – The patient started our alternative treatment.
L.C.E. Biobran Mgn-3, prostasol (herbal composition) Imupros (vitamins,
trace elements, lycopene, ginseng, etc…) together with an anticancer diet.
After 4 months the patient felt better and gradually started to improve. PSA
decreased to 328 ng/ml. After 8 months to 58 ng/ml and to 2.8 ng/ml and
final to 1.58 ng/ml.
After 6 months of treatment new bone scan showed a 50% decrease of
bone lesions and after one year a total elimination. The treatment was
followed during the whole year.
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91
Cancer of the Colon with Metastasis to Lung and Liver
Patient female – 56 years old – Diagnosed in May 2010 with colon Cancer: stage IV
with metastasis spread to liver.
Surgery and Chemotherapy.
June 2012 - New scan had shown more metastasis to the liver. Patient was
submitted to more chemotherapy with a period of remission.
September 2013 - Recurrence and dessimination of metástases to lung, ganglions
and liver. High tumor marker level Ca 19.9 848 U/ml. CEA 260 ng/ml. The patient
came in our clinic in a desesperate condition.
Treatment: Biobran, Mgn-3, Curcumin, L.C.E., SOD, Alpha lipoic acid, followed by an
aggressive anticancer diet, cocktails of vegetable juices.
2015 - Patient was in bad physical condition, anemic, much coughing from lung
metastasis, felt tired, had chest pains and some difficulty breathing.
92
Results of Molecular Markers Testing:
Normal p53 gene but not activated – absence of normal p53 proteins level – Mutated
protein N.D.
BCL2 overexpression – 459 unit/ul of plasma (normal up to 10 units)
Bax gene expression - 178 units/ul of plasma (reference range 10 units)
BCL2/Bax ratio – 0.4 (bad ratio)
TM2-Pyruvate Kinase level – 231 units/ml of plasma (reference range 5-15)
High metabolic activity of tumor – inflammatory process
2016 - New scan had shown large lung lesions but less active, some smaller, other
calcified. Some good improvement in June 2016, patient felt better.
Scan had shown diminution of the lesions – Ca 19-9 decrease to 150 U/ml and CEA
to 40 ng/ml. Also blood value was normal despite chemotherapy.
2017 - Patient looks in better physical and psychological condition, looks much
better and breathes normally and can do her work. This is a good life extension. In
2015 her doctor told her that she surpassed the 2 year life expectancy statistic. Now
it has been 4 years.
She is still taking her treatment and never stops Biobran and Curcumin intake,
taking LCE with some intervals while keeping on her diet taking vegetable juice.
Cancer of the Colon with Metastasis to Lung and Liver
93
Cancer of the Colon with Metastasis to the Lungs and Liver
The Patient in March 2017
94
Cancer of the Colon with Metastasis to the Lungs and Liver
95
The same patient 7 months later in October 2017
with a good physical prospect, good quality of life,
happy despite the “death sentence” giving to her by
doctors nearly 5 years ago. She is taking BioBran from
the beginning alone with other supplements.
Patient female – 50 years old with a metastasic recurrence from
breast cancer (2000) in 2004 with multiple lesions disseminated in the
skeleton. Strong pains and after one year of the new protocol of
chemotherapy a new bone scan (May 2005) showed more
disseminated lesions in comparison to 2004. Poor response and
evolution of the disease. The complete case fully illustrated is
available in English and French.
X Ray of the Spine
After 3 months of
combined therapy +
chemotherapy.
Total elimination of the
very large lesions in the
illium and spine.
Jurasunas Serge, ND
97
Tumor Marker – CA 15.3
113U/ml
55.2 U/ml
23.6 U/ml
June
2005
August
2005
January
2006
98
Boy 10 years old
Clinical case: Neuroblastoma localized at the abdomen
Area with a large lesions of 9,8 and 6,2 cm. Tumor could not be completely
removed by surgery. The boy started with chemotherapy and radiation.
Metastases invaded the brain and bone skeleton. 3 brain surgeries with partial
resection followed by more chemotherapy, but each time tumor started to grow.
With the evolution of the disease the boy got real worse developing peripheral
Neuropathy, became totally paralysed and could not walk or move his hands or
fingers.
AFTERBEFORE
99
Case of 7 year old girl Anoka diagnosed
with a astrocytoma grade II in September 2008.
AFTER A
YEAR
BEFORE
100
Story of a 6 month old baby with glioma stage II
(Surgery in Paris, but no complete resection of the
tumor that started to grow again) Parents refused
Chemotherapy – second photo is the same boy
at 7 years old.
Old Case
Breast Cancer Survivor
1994 – Age 36 years.
Bad prognostic of 18 ganglions
with metastasis – Liver and
bone metastasis.
June 2008 – Age 50 years.
Participating as a witness in
our psychological support
group meetings for our cancer
patients – 2017 – The patient is
still in remission at 59 years
old.
102
Group of Cancer Patients at Holitherapia Clinic
Meeting: Mind and Body Club
Thank You for
Your Attention!
Don’t Let the Cancer Kill You, but Rather Kill the Cancer!
103

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How to Understand and Treat Cancer with Modern Methods. Public Presentation By Professor Serge Jurasunas –Zagreb, Croatia – 2-27-2018

  • 1. 28. February 2018 Zagreb Croatia NEW MODERN WAY to APPROACH CANCER: How to Understand and Treat Cancer with Modern Methods Speaker: Serge Jurasunas N.D. M.D (h.c) M.D.(Hom) Professor of Naturopathic Oncology www.sergejurasunas.com
  • 2. 2 Serge Jurasunas N.D.M.D. (Hom) Pioneer in Natural Medicine and Naturopathic Oncology Practitioner – Researcher – Author – 50 Years of Practice
  • 3. Serge Jurasunas N.D.M.D. (Hom) Pioneer in Natural Medicine and Naturopathic Oncology Practitioner – Researcher – Author – 50 Years of Practice Author of 7 books 2017 New book: Health and Disease Begin in the Colon - Featuring Professor Serge Jurasunas’ Natural Medicine www.sergejurasunas.com Blog: http://naturopathiconcology.blogspot.com 3
  • 4. New Modern Way to Treat Cancer - Strategic Immunotherapy, Apoptosis and Angiogenesis 4
  • 5. 5 International Publication of Articles by Serge Jurasunas in Various Health Magazines:  USA  Germany  Japan  Lithuania  Belgium
  • 6. 6 5th International BioBran Workshop, 9-11, June 2017, Krakow, Poland Oncologist Joseph Brenner M.D., Hegyi Gabriela M.D., Prof.Jurasunas N.D., Prof. Tibor Hajto and Immuno-Oncologist Prof.Rupert Handgretinger
  • 7. 7 New Modern way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 8. 8 New Modern Way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 9. 9 Excess Red Meat Intake Increases the Risk of Cancer ( Colon – Breast – Stomach) Read my book: Health and Diseases Begin in the Colon
  • 10. 10 New Modern way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 11. 11 There is an Epidemic of cancer. 1900: 1 person out of 20 gets cancer 1990: 1 person out of 10 gets cancer 1997: (USA) 1 out of every 2 men and 1 out of every 3 women will be diagnosed with cancer in their lifetime, soon will be 1 in two women and the statistics seem to be darker for the future. The world health Organization (WHO) reported that the cancer prognostic for 2020 will INCREASE between 50-100% in the number of the sick and for deaths. Every minute in the US a cancer patient is dying form Cancer: 60 per hour, 1440 per day or 43200 per month. Over half million per year. CHILDREN: Every year the number of children dying of cancer grows. 2 out of 3 US cancer patients die before the 5 year survival mark, undergoing conventional treatment. What can be done about this ?
  • 12. 12 New Modern Way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 13. 13 New Modern way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 14. Angiogenesis: DNA Mutation Begins After Radiation Exposure –Red Tissues Show Inflammation 14
  • 15. Tumor Immunology & Immunotherapy 15
  • 16. 16 New Modern way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 17. 17 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 18. 18 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis. Cancer is like a Monster with Several Heads.
  • 19. 19 Cancer cannot be attacked only in one direction, but several directions at the same time. You need more than one arrow to kill the tumor.
  • 20. 20  Many cancer and pre-malignant forms are hard to detect or are asymptomatic for many years  Conventional diagnostics are inefficient in cancer prevention
  • 21. 21 Declaration signed December 23th, 1971 with the promise to have cancer cured within the next 5 years. Since, nearly $ 300 billion has been spent with no cure yet!!! 1971 Declaration of War on Cancer by US President Richard M. Nixon signing the National Cancer Act
  • 22. Where are We Today with Cancer ? Despite the progress in Oncology and some benefit in the gold standard of palliative therapy, surgery and radiation, conventional treatment has not achieved the hope and expectation to cure cancer. In metastasic Cancer: Oncology is not better than 30 years ago. There has been no significant change in the survival rate. 22
  • 23. 23 New Modern way to Treat :ancer, Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 24. Problems of Conventional Oncology → Chemotherapy is toxic, induces adverse effects and can be fatal to patients → Resistance of cancer to chemo-radiation → Induces adverse effects including death → Many anticancer drugs show little or no efficacy → Chemotherapy and radiation is carcinogenic by itself responsible for second cancer → Metastasis cancer is incurable and responsible for 95% of deaths → Recurrence is sƟll too high 24
  • 25. 25
  • 26. 26 Cytotoxic Chemotherapy o More chemotherapy is more toxic, but not necessarily more effective o Chemotherapies are selected empirically o After 6 months chemotherapy loss effectiveness o Chemotherapy does not kill cancer stem cells
  • 27. Removing a tumor by surgery is like removing a large patch of weeds in your garden's soul. You leave some weed roots behind that grow again, the same as with a tumor and metastasis. 27
  • 28. 28 Cancer cells are like weeds in your garden, you spray them directly with toxic insecticides and kill not only the weeds but the good plants as well, then your soil becomes depleted and sick.
  • 29. 29 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 30. 30 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 31. 31 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 32. New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis Cancer is a Disease of the Cell Cycle 32
  • 33. 33 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis. Over 60 000 papers Called ‘The Garden of our Genome’
  • 34. 34 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 35. New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis 35
  • 36. 36 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 37. 37 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 38. New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis 38
  • 39. 39 New Modern way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis.
  • 40. Growth of Xenograft Tumors Tumors with an intact p53 gene regressed during the treatment, whereas the tumors with defective p53 genes continued to grow. 40
  • 41. 41 P-53 Tumor Suppressed Gene: Understanding P53 based Anticancer Therapies utilizing Dietary Agents By Serge Jurasunas Published in Townsend Letter, The Examiner of Alternative Medicine USA ( August/Sept 2015
  • 42. 42 New Modern way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 43. Video from Researcher , Dr. Marc Diederich from the University of Singapore (From My Science Work) A number of recent articles published in various countries have shown that reactivating the immune system to treat cancer is now attracting oncology theroists. 43 Reactivating the Immune System Against Cancer: A Role for Natural Compounds
  • 44. 44 New Modern way to Treat Cancer: Strategic, Immunotherapy, Apoptosis and Angiogenesis
  • 45. 45 Are we nearing a cure for cancer? The Holy Grail is closer than ever, oncologist claims. Dr. Rebecca Kristeleit of University College London, Hospital, said advances in a revolutionary treatment called Immunotherapy were now occurring at a rapid rate… We are beginning to start thinking about using the word cure.
  • 46. 46 Biobran/Mgn3 The BREAKTHROUGH in Immuno-Oncology Two decades of studies show that Biobran/Mgn3, a natural compound made from modified rice bran is a potent immunomodulator of NK cells, our most important line of defense against cancer including T- cells, B-cells and global immune system function. New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 47. Dietary fibers are eliminated by the intestine but Biobran is absorbed in the small intestine practically undigested entering into the blood to become a nutritional food that activates N.K.cells and optimizes immune function when taken orally. 47
  • 48. 48 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 49. 49 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 50. Biobran increases the Curve of NK Cells If you prescribe 2g of Biobran to volunteers then you can see a curve of NK cells increasing about 60% after two weeks. But if you continue, you can achieve up to 200 even 300% or more NK cell number and activity. NK cells are here but not activated to release their toxic enzymes (perforin) through the membrane of cancer cells. Ghoneum M. “Enhancement of Human natural killer cells activity by modified arabinoxylan from rice bran. (Mgn3) Int. Immunotherapy 1998. XIV.89-99 50
  • 51. - Cancer patients on chemotherapy have a depressed NK cell activity attributed to a decrease or absence of perforin and granzyme (1). - Mgn3 Biobran studies have shown that the treatment causes an increase in the granular content (perforin and granzymes) of NK cells. - It also results in an increased NK cell binding capacity to cancer cells. (1) Culler S.P. Brunet M., Martin S.J. – Ganzymes in cancer and immunity – Cell Death Differ. 2010.17-616-623 51 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 52. 52 Treatment with BioBran causes a remarkable increase in NK cells activity in various cancer after 2 weeks. PERCENTAGE OF INDUCTION Breast cancer = 154 -332% Leukemia = 100-240% Cervical cancer = 100-275% Prostate = 174-385% Multiple Myeloma = 100-537% Enhancement of NK cells activity continue to rise at 3-6 months after treatment. (1) (1) Ghoneum M. Narmatalla G. N.K Immunomodulatory function in 27 cancer patients by Mgn3, a modified arabinoxylan from rice bran. (2) The abstract of 87th Annual Meeting of the American Assn. for cancer Research. Wash. D.C April 20-24.1996.
  • 53. 53 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis NK cell attacking cancer cell after being activated with the natural compound Rice Bran Arabinoxylan Compound
  • 54. One Activated NK Cell Attacking 3 Cancer Cells 54
  • 55. 55
  • 56. 56 Biobran Enhances the Effect of Chemotherapy Leading to Effective Treatment at Low Dosage with Less Toxic Effect and More Results New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 57. Some of Our Clients Have Been Taking Biobran on Long-Term Follow Up from 2-4-7 Years Without Toxicity 57
  • 58. 58
  • 59. 59 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis NK Cell Activity Increases Survival of Cancer Patients. In different types of human tumors including melanoma, breast cancer, bladder, colon, prostate, ovary, rectum, glioblastoma; longer survival has been observed in patients with a higher number of lymphocytes and NK cells. References: Jass J.R. Lymphocytic infiltration and survival in rectal cancer J.Clin.Pathol. 1986-19-585-589 Clemente CG et al. Prognosis value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer. 1996 – 77 -1303-1310
  • 60. 60 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis BIOBRAN (MGN-3 arabinoxylan compound). CONCLUSION: In human studies BioBran has been shown to be the most effective in activating NK cells and optimizing immune function when taken orally before or after meals.
  • 61. CURCUMIN – A Potent Anticancer Agent (Yellow ingredient derived from curcuma longa.l one of the most extensively investigated phytochemical compounds with ANTICANCER properties. (1) (1) Anticancer potential of curcuma. An old spice with new targets. Bharat B. Aggarwal Ph.D. University of Texas M.D. Anderson Cancer Center. Houston. TX.USA 61 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 62. 62 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 63. Human Melanoma Cell Line SK-MEL-37 Cells have been Treatd with 15uM and 20uM of Curcumin for 24 hours: (B and D) Entering into Apoptosis. (A and C UnTreatd Cells). These cells have demonstrated to be resistant to doxorubicin, cisplatin in culture but sensitive to curcumin treatment. Marcella Lemos Carneiro – Morphological alterations and Go/G1 cell cycle arrest induced by curcumin in human SK- MEL-37 melanoma cells. Braz.arch.Biol. Technol.Vol.53 n.2.Curitiba.April.2010 Curcumin potentializes the effectiveness of chemotherapy in a variety of cancers including breast, ovarian, colon and pancreatic and could become a promising tool. 63
  • 64. 64 Curcumin Increases the Sensitivity of Drug Treatment in Breast, Ovarian, Cervical, Pancreas and Colon Cancer - 5 Fu - Taxol - Pactitaxel - Cisplatin - Adramycin - Daunorubicin Koo J.Y. et al, 2002, VBS et al. 2003, Chan M.M., 2003, Chuang S.E. et al, 2002 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 65. A Study in Breast Cancer (Bayet-Robert and Collegues 2010) Oral curcumin and docetaxel administered to INOPERABLE breast cancer patients with advanced tumors and metastasis, became OPERABLE after the combination therapy. Patients had LOWERED tumor MARKERS and V.E.G.F. levels indicating REDUCED cancer cell SURVIVAL and ANGIOGENESIS, tumor SIZE and inflammation. (1) (1) Serge Jurasunas – Complementary Approach to Breast Cancer. A Case with Multiple Liver Metastasis is Free from Disease. Townsend Letter August/September 2015. 65 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 66. Synergetic Effect of Biobran MGn3 and Curcumin in Cancer Treatment with Chemotherapy - Faster reduction and/or elimination of secondary nodules in cancer recurrence. -Significant reduction of large tumors when taken together with chemotherapy. - Advanced cancers with multiple metastasis (Liver, lung, etc.), having received poor prognosis with a combination of chemotherapy, has resulted in prolongation of lifespan (6-8 years) with maintenance, along with an improved quality of life (QOL). 66 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 67. New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis 67
  • 68. 68 Microbiome: A new target in Immuno-oncology. Stronger immune response to kill cancer cells.
  • 69. 69 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 70. 70 Distribution and abundance of bacteria in human gastro-intestinal tract
  • 71. 71 TOP KNOWN BENEFITS OF HUMAN MICROBIOME (Commensals bacteria)  Preventing infection by pathogens bacteria  Development of the immune system  Digestion of food  Vitamins production ( B2, B12, K, Folic acid  Toxin degradation
  • 72. 72 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis
  • 73. New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis 73
  • 74. 74 Foods That Balance the Gut Microbiome > Fibers > Kefir > Vegetables > Miso > Fruits > Probiotics supplementation > Fermented food > Lacto-fermented Vegetable Juice > Buttermilk > Pickles > Natto > Apple Cider Vinegar > Kombucha > Fermented Cabbage AVOID STRESS DURING MEALS! See my article: “Can Food Prevent and be Efficient in Cancer Treatment”, fully illustrated. www.slideshare.net/sheldonstein
  • 75. 75 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis Protocol for Cancer Patients: Biobran, 1 bag of 1gr 3 times per day, 20 min. after meal. Curcumin, 1 bag of 1500 mg liquid diluted in water to take 3 times per day between meal. Alpha lipoic Acid, 300 – 400 mg per day. Additionally as a support to nutritional needs: Detoxification, boosting mitochondria function and to activate ATP energy and reduce tumor aggressivity. Enzyme Yeast Cells (Zell-Oxygen) See my diet paper: “Can Food Diet Prevent and Be Efficient in Cancer Treatment” Available on my blog: www.Naturopaticoncology.blogspot.com
  • 76. What I Should Eat Now !
  • 77. 77 New Modern Way to Approach Cancer: Strategic Immunotherapy, Apoptosis and Angiogenesis Prevention During cancer treatment only YOU can make the Choice and dedice which road to take.
  • 78. 78 Food is Powerful Medicine “Three times a day, day after day, we are eating natural foods that can influence our GENES and help us to PREVENT and FIGHT CANCER” - Prof. Serge Jurasunas ( N.D. M/D.(h.c)
  • 79. 79
  • 80. A Few Interesting Case Histories We Don’t Cure All the Cancers but… -Many cases after 25-30 years are alive and doing well. -Several have had a 10 year extension. -Several advanced cases have improved their quality of life with a life spent up to 7 years , including prostate cancer, multiple myeloma, breast cancer and pancreatic cancer. -Unfortunately many cases come in too late that end up as fatalities from excess chemotherapy. -Overall our treatments have demonstrated efficacy, help the patient by reducing toxic effects, improve chemotherapy effectiveness, quality of life and increase life expectancy. 80
  • 81. 81 The Toxic Effects of Chemotherapy Female: Breast cancer patient suffering from strong adverse effects from chemotherapy. Paralyzed from a peripheral Neuropathy.
  • 82. 82 Improving Patient Quality of Life, Less Adverse Effects and Increasing Chemotherapy Effectiveness F. 71 year old- Breast Cancer – Chemotherapy with severe toxic adverse Effects- Developed a peripheral neuropathy – Paralyzed on the first consulation. F. 44 year old- Breast Cancer – With multiple metastasis to liver – Follows our treatment during Chemotherapy remission CASE published in Townsend Letter August/September 2015
  • 83. F.41 years – Asympthomatic Prime Lesions 18 cm – Secondary Lesions 8 cm Combination of chemotherapy with our complementary treatment that targets apoptosis, angiogenesis, immune activity – Anticancer Diet 83 Advanced Gastric Cancer - Results of Blood Analysis July 2015 April 2015 July 2015 April 2015 Lesion of 30,1 mm Lesion of 48,7 mm Lesion of 18 cm
  • 84. p53 Gene Expression p53 Protein Level mutated p53 Protein Level normal 58 units/µl of plasma 35,4 units/µl of plasma 1 unit/µl of plasma 72,4 units/µl of plasma Reference range: 10-50 units/µl of plasma Reference range: 0,10 – 1,00 units/µl of plasma Reference range: 5 - 15 units Tumor Marker 2 – Pyruvate Kinase TM2.PK Advanced Gastric Cancer - Result of Blood Analysis 1st Test: 28/04/2015 2nd Test: 26/06/2015 p53 Gene Expression 223 units/µl of plasma p53 Protein Level n normal 4 units/µl of plasma p53 Protein Level mutated Not detectable 23,8 units/µl of plasma Tumor Marker 2 – Pyruvate Kinase TM2.PK Comment: We significantly increased about 4 times the expression of p53 gene and increased only to a certain extent normal p53 protein. We reversed the production of mutant protein to normal wild type. TM2.PK activity decreased to an almost normal range. After the applied therapy 84
  • 85. 85 Advanced Gastric Cancer - Photo taken on May, 2017
  • 86. 86 Breast Cancer with Multiple Metastasis to Liver Complete Case Published in the Townsend Letter August/Sept 2014 or online at www.sergejurasunas.com Patient female, 44 years old diagnosed in October 2011 with a stage III left breast cancer, with dissemination of about 30 lesions to the liver; up to 1,5cm size for many localized in the left lobe, and segment III and IV of the right lobe. Breast tumor was about 3.5cm with inflammation spread to neighboring tissues; many swollen lymph nodes were diagnosed on the left part of the neck. Chemotherapy was suggested before surgery to reduce the tumor and the inflammation. January 2012 – The patient came into our clinic suffering from adverse side effects having had very little response from chemotherapy. She felt tired, nausea, loss of appetite, anxiety. We had taken 3 different tests: Live Blood Analysis, Oxidative Dried Blood Test and Molecular Markers Testing. These tests showed very high BCL2 activity, low BAX gene activity and especially very high VEGF levels showing activated angiogenesis in the solid tumor. Treatment – L.C.E., Biobran MGN-3, Curcumin and Anticancer Diet After 2 months of treatment the inflammation was almost gone, in the same way as the swallowed ganglions and reduced tumor. Surgery was done followed by chemotherapy and our treatment. In 2003 a new scan showed total elimination of the 30 liver nodules and complete remission. In 2017 the patient was still in remission but still comes in regularly for our check up exams.
  • 87. 87 THE ANTI-TUMOUR EFFECTS OF THE APPLIED TREATMENT 02/12/12370 05/12/12461 Ref. Range p53 gene expression 200 427 10-50 units/ul of plasma p53 level mutated ND ND ND units/ml of plasma p53 level wild ND 0,4 0.10-1.00 units/ml of plasma Bcl-2 gene expression 8000 796 <10 units/ul of plasma Bax gene expression 167 1543 10-100 units/ul of plasma Bcl-2/Bax ratio 0.02 1.93 Surviving gene expression 171 900 <10 units/ul of plasma P21 gene expression 139 738 10-50 units/ul of plasma Surviving/p21 ratio 0.8 0.8 VegF gene expression 2353 ND 10-100 units/ul of plasma A Complementary Approach to Breast Cancer: A Case with Multiple Liver Metastasis is Free from Disease Complete Report – Townsend Letter Magazine – August/Sept 2014 Breast Cancer with Multiple Metastasis to the Liver
  • 88. 88 Breast Carcinoma Stage IV with Multiple Metastasis to Ganglions, Liver, Bone, Pleura and One Nodule to Right Lung Patient female – 42 years old – Breast carcinoma stage IV with multiple metastasis to ganglions, liver, bone, pleura and one nodule to right lung. The patient underwent a radical mastectomy and started chemotherapy on October 2015. A February, 2016 scan showed more dissemination of metastasis, which increased in April, with poor physical condition. There was strong resistance from cancer cells to chemotherapy with more dissemination of metastasis. The patient came to us in May 2016 and immediatly started our treatment. Biobran MGN-3, 3 gr per day – Curcumin, 4,5 gr per day – Enzyme yeast cells preparation, 40 ml per day – Coenzyme Q10, 300 mg per day followed by an aggressive anticancer diet and plenty of vegetable juices which is important in any cancer treatment. August 2016, a new scan showed major improvement, about a 70% reduction in nodule size, demonstrating synergy with our combination therapy with chemotherapy by increasing effectiveness by targeting apoptosis, angiogenesis and immune cell activity. Results in the next slide reveal the patient got worse from chemotherapy alone, but after 3 months had a much better scan after our complementary therapy.
  • 89. 89 Advanced Prostate Cancer (1) Patient male – 71 years old – Advanced prostate cancer. The patient was diagnosed in 2005 with a prostate cancer with dessimination of bone metastasis. Very high PSA 1.260 ng/ml. No surgery, chemotherapy or radiation was suggested but only a hormonal therapy, but without result. The patient was in a very bad condition. 2006 – The patient started our alternative treatment. L.C.E. Biobran Mgn-3, prostasol (herbal composition) Imupros (vitamins, trace elements, lycopene, ginseng, etc…) together with an anticancer diet. After 4 months the patient felt better and gradually started to improve. PSA decreased to 328 ng/ml. After 8 months to 58 ng/ml and to 2.8 ng/ml and final to 1.58 ng/ml. After 6 months of treatment new bone scan showed a 50% decrease of bone lesions and after one year a total elimination. The treatment was followed during the whole year.
  • 90. 90
  • 91. 91 Cancer of the Colon with Metastasis to Lung and Liver Patient female – 56 years old – Diagnosed in May 2010 with colon Cancer: stage IV with metastasis spread to liver. Surgery and Chemotherapy. June 2012 - New scan had shown more metastasis to the liver. Patient was submitted to more chemotherapy with a period of remission. September 2013 - Recurrence and dessimination of metástases to lung, ganglions and liver. High tumor marker level Ca 19.9 848 U/ml. CEA 260 ng/ml. The patient came in our clinic in a desesperate condition. Treatment: Biobran, Mgn-3, Curcumin, L.C.E., SOD, Alpha lipoic acid, followed by an aggressive anticancer diet, cocktails of vegetable juices. 2015 - Patient was in bad physical condition, anemic, much coughing from lung metastasis, felt tired, had chest pains and some difficulty breathing.
  • 92. 92 Results of Molecular Markers Testing: Normal p53 gene but not activated – absence of normal p53 proteins level – Mutated protein N.D. BCL2 overexpression – 459 unit/ul of plasma (normal up to 10 units) Bax gene expression - 178 units/ul of plasma (reference range 10 units) BCL2/Bax ratio – 0.4 (bad ratio) TM2-Pyruvate Kinase level – 231 units/ml of plasma (reference range 5-15) High metabolic activity of tumor – inflammatory process 2016 - New scan had shown large lung lesions but less active, some smaller, other calcified. Some good improvement in June 2016, patient felt better. Scan had shown diminution of the lesions – Ca 19-9 decrease to 150 U/ml and CEA to 40 ng/ml. Also blood value was normal despite chemotherapy. 2017 - Patient looks in better physical and psychological condition, looks much better and breathes normally and can do her work. This is a good life extension. In 2015 her doctor told her that she surpassed the 2 year life expectancy statistic. Now it has been 4 years. She is still taking her treatment and never stops Biobran and Curcumin intake, taking LCE with some intervals while keeping on her diet taking vegetable juice. Cancer of the Colon with Metastasis to Lung and Liver
  • 93. 93 Cancer of the Colon with Metastasis to the Lungs and Liver The Patient in March 2017
  • 94. 94 Cancer of the Colon with Metastasis to the Lungs and Liver
  • 95. 95 The same patient 7 months later in October 2017 with a good physical prospect, good quality of life, happy despite the “death sentence” giving to her by doctors nearly 5 years ago. She is taking BioBran from the beginning alone with other supplements.
  • 96. Patient female – 50 years old with a metastasic recurrence from breast cancer (2000) in 2004 with multiple lesions disseminated in the skeleton. Strong pains and after one year of the new protocol of chemotherapy a new bone scan (May 2005) showed more disseminated lesions in comparison to 2004. Poor response and evolution of the disease. The complete case fully illustrated is available in English and French. X Ray of the Spine After 3 months of combined therapy + chemotherapy. Total elimination of the very large lesions in the illium and spine. Jurasunas Serge, ND
  • 97. 97 Tumor Marker – CA 15.3 113U/ml 55.2 U/ml 23.6 U/ml June 2005 August 2005 January 2006
  • 98. 98 Boy 10 years old Clinical case: Neuroblastoma localized at the abdomen Area with a large lesions of 9,8 and 6,2 cm. Tumor could not be completely removed by surgery. The boy started with chemotherapy and radiation. Metastases invaded the brain and bone skeleton. 3 brain surgeries with partial resection followed by more chemotherapy, but each time tumor started to grow. With the evolution of the disease the boy got real worse developing peripheral Neuropathy, became totally paralysed and could not walk or move his hands or fingers. AFTERBEFORE
  • 99. 99 Case of 7 year old girl Anoka diagnosed with a astrocytoma grade II in September 2008. AFTER A YEAR BEFORE
  • 100. 100 Story of a 6 month old baby with glioma stage II (Surgery in Paris, but no complete resection of the tumor that started to grow again) Parents refused Chemotherapy – second photo is the same boy at 7 years old.
  • 101. Old Case Breast Cancer Survivor 1994 – Age 36 years. Bad prognostic of 18 ganglions with metastasis – Liver and bone metastasis. June 2008 – Age 50 years. Participating as a witness in our psychological support group meetings for our cancer patients – 2017 – The patient is still in remission at 59 years old.
  • 102. 102 Group of Cancer Patients at Holitherapia Clinic Meeting: Mind and Body Club
  • 103. Thank You for Your Attention! Don’t Let the Cancer Kill You, but Rather Kill the Cancer! 103