Future Market Insights has announced the addition of the “Sulphonamides Market: Global Industry Analysis and Opportunity Assessment 2016-2026" report to their offering.

1. Sulphonamides Market Value Share, Analysis and
Segments 2016-2026
November 2016
©2015 Future Market Insights, All Rights Reserved
Report Id : REP-GB-1641
Status : Ongoing
Category : Healthcare, Pharmaceuticals & Medical Devices

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4. Sulfonamides are organic sulfur compounds that contain the radical SO2NH2 (the amide of sulfonic acid),
which are also known as sulfa drugs or sulpha drugs. These are first anti-microbial drugs developed to
treat bacterial infections in humans and animals. Sulfonamides interfere in folic acid synthesis process in
bacterial cell by competitive inhibition of dihydropteroate synthetase (DHPS) enzyme competing with
para amino benzoic acid (PABA). Folic acid is a precursor of ribonucleic acid (RNA) and deoxyribonucleic
acid (DNA) formation in bacterial cell. Sulfonamides limits the growth of bacteria and thus sulfonamides
act as bacteriostatic agents. A few sulfonamides are highly water-soluble such as sulfisoxazole
(sulfafurazole) and sulfasomidine, which are rapidly excreted through the urinary tract (more than 90% in
24 hr) mostly in an unchanged drug form; due to this pharmacokinetic property these sulfonamides are
primarily used to treat urinary tract infections (UTI’s). In addition, some of the sulfonamide derivatives,
such as sulfaguanidine, are insoluble in nature thus they are not absorbed from the gastro intestinal (GI)
tract (less than 5%), therefore, these sulphonamides are used for treatment of ulcerative colitis. Bayer AG
was the first company who started experimenting with Prontosil in 1932. Many people are allergic to
sulfa drugs and thus sulfonamides are prescribed with caution. Sulfonamides have potential to cause fatal
side effects including urinary tract disorders, haemopoietic disorders, hyper sensitivity reactions and
porphyria. Most serious side effects include toxic epidermal necrosis, hemolytic anemia, agranulocytosis,
fulminant hepatic necrosis, thrombocytopenia and Stevens Johnson syndrome.
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Sulphonamides Market
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5. Based on type of administration, global sulfonamide market is classified as follows:
 Oral
 Orally Absorbable Sulfonamide
 Short Acting (sulafadiazine, sulfacytine, sulfamethizole, sulfisoxazole)
 Intermediate Acting (sulfamethoxazole, sulfmoxole)
 Long Acting (sulfadoxine, sulfamethopyrazine)
 Orally Non Absorbable Sulfonamide (sulfasalzine, osalazine)
 Topical Agents (Silver sulfadiazine, sulfacetamide, mafenide)
Based on type of therapeutic use, global sulfonamide market is classified as follows:
 Skin Infections
 Gastro Intestinal Tract (GIT) Infection
 Meningitis
Sulphonamides Market
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6.  Urinary Tract Infection (UTI) Infection
 Respiratory Tract Infection (RTI)
 Leprosy
 Bowel Disinfections
 Malaria
 Nocardiosis
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Increasing prevalence of chronic diseases worldwide and the substantial availability of various
sulfonamide drug formulations at reasonable price to meet the ever-growing demand are the major
factors contributing to the growth of the global sulfonamides market. In addition, increasing R&D
activities in pharmaceutical companies is resulting in novel and improved classes of sulfonamides with
improved therapeutic activity is another major driver, fueling the global sulfonamides market growth
over the forecast period. However, increasing side effects associated with the use of sulfa drugs such as
urinary tract disorders, kernicterus and hypersensitivity and increasing use of broad spectrum Some
Sulphonamides Market
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7.  antibiotics with lesser side effects such as quinolones, macrolides are expected to restrain the growth
of global sulfonamides market.
 Geographically global sulfonamides market has been segmented into North America, Latin America,
Europe, Asia-Pacific & Japan, Middle East Africa regions. North America region has been estimated as
most dominant region in the global sulfonamides market owing to presence of harmonized regulatory
structure, high rates of awareness regarding sulpha drugs and its therapeutic uses, and highly
developed healthcare infrastructure. Asia-Pacific & Japan is a lucrative market for global sulfonamides.
Countries in the Asia Pacific regions include, greater China and India together account for largest
population pool in the world and thereby have large pool of geriatric population in addition to rapidly
increasing medical tourism industry and increasing healthcare spending are some of the factors that
are expected to fuel the growth of sulfonamides market in the region.
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Sulphonamides Market
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