1. Eflornithine hcl medication acts as hair growth
inhibiting agent. It is used topically to reduce
unwanted facial hair also called facial hirsutism in
women. It is found to be highly effective in reducing
excessive hair growth. It is also used in the form of
injection for treating African trypanosomiasis or
sleeping sickness. Eflornithine hydrochloride cream
is for topical use in women suffering from facial
hirsutism. It is an irreversible inhibitor of ornithine
decarboxylase ODC, an enzyme that catalyses the
conversion of ornithine to putrescine, which plays an
important role in cell division and proliferation in the
hair follicle.
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2. Excessive growth of facial or body hair in women is called hirsutism It is not a
disease It is usually the result of an underlying adrenal, ovarian, or central
endocrine imbalance
3. Facial hirsutism often leads people to anxiety and depression due to
avoidance of social situations The condition usually develops during puberty
and becomes more pronounced as the years go by However, it can appear at
any age due to an inherited tendency, over-production of male hormones
called androgens, medication or diseases
4. A woman whose hirsutism is caused by an increase in male hormones has a
pattern of hair growth similar to that of a man A woman whose hirsutism is not
hormone-related has long, fine hairs on her face, arms, chest, and back
Females with this condition usually have irregular menstrual cycles
5. They sometimes have small breasts and deep voices, and their muscles and
genitals may become larger than those without this condition Different types
of hirsutism are idiopathic hirsutism and secondary hirsutism
6. Idiopathic hirsutism is generally hereditary due to the family history disorder
Women with idiopathic hirsutism have normal menstrual cycles and no
evidence of any of the conditions associated with secondary hirsutism
7. Secondary hirsutism is associated with polycystic ovary syndrome Polycystic
ovary syndrome is an inherited hormonal disorder characterized by menstrual
irregularities, biochemical abnormalities and obesity
8. This type of hirsutism may also be caused by malfunctions of the pituitary or
adrenal glands, use of male hormones drugs or due to adrenal or ovarian
tumors Hirsutism triggered by tumors is very unusual
9. Treating with eflornithine hydrochloride helps women reduce their facial how
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