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Welcome to the 5th HARC Forum

Monitoring variation in healthcare quality -
an evidence base to improve healthcare

                                   HARC is a as a partnership between
   the Sax Institute, Clinical Excellence Commission and the Greater Metropolitan Clinical Taskforce
Keynote Speaker
Professor Elliott Fisher
 Professor of Community and Family Medicine at Dartmouth Medical School and Director of the Center
for Health Policy Research at the Dartmouth Institute for Health Policy and Clinical Practice


 US Dartmouth Atlas of Health Care Project -
monitoring and explaining variation in healthcare to
improve the health system
Monitoring Variation in Health Care:
                An approach to improving the
            evidence base for practice and policy




    Elliott S. Fisher, MD, MPH

 Professor of Medicine and Community
         and Family Medicine
      Dartmouth Medical School

Director for Population Health and Policy
The Dartmouth Institute for Health Policy
           and Clinical Practice
Houston, we’ve got a problem…

The usual suspects:
      Rising costs
      Uneven quality
      Declining access to care

Some looming challenges
    Loss of professional authority of physicians
    Integrity and relevance of academic medicine
Houston, we’ve got a problem…

   Traditional diagnoses:                           Prescriptions:
            A shortage of money                           Spend more
            A shortage of doctors                         Train more
            A shortage of economists                      Focus on prices




Every system is perfectly designed to get the
results that it achieves
                                    Paul Batalden


Insanity: doing the same thing day after day and
expecting different results
                                    Einstein
Rethinking health care
Origins of the Dartmouth Institute – and Dartmouth Atlas Project




 Science, December 14,
 1973; Volume 182, pp
 1102-08
Rethinking health care
A simple analytic framework; a shared vision

Application of epidemiologic methods to health care services
   Define population at risk
   Define events
   Examine variations across relevant systems -- providers
   Ask good questions

Organizational Development
   Independent institute within Medical School
   Interdisciplinary research group; all with departmental appointments
   Governance through a shared vision:
      Exploring the causes and consequences of unwarranted variations
      Commitment to making a difference (locally, regionally, nationally)
   Major long-term funding helps maintain focus
Rethinking health care
The Dartmouth Atlas of Health Care
                                     Methods:
                                     Population at risk – over 65
                                     Compare Hospital Referral Regions
                                     Events of interest -- many
Rethinking health care
The Dartmouth Atlas of Health Care
                                     Categories of care
                                     Safe and effective care
                                     Preference sensitive care
                                     Supply-sensitive care
Rethinking health care
Preference-sensitive care                     Transurethral Prostatectomy for
                                               Benign Prostatic Hypertrophy
                                                         per 1000

                                           15.0

                                           13.0




                            TURP for BPH
                                           11.0

                                            9.0

                                            7.0

                                            5.0

                                            3.0
Rethinking health care
Safe and Effective Care

                                                                30 Day Mortality Following CABG




                          30-Day Mortality Following CABG (%)
                                                           12.0


                                                           10.0


                                                                8.0


                                                                6.0


                                                                4.0


                                                                2.0
Rethinking health care
Spending – and supply sensitive care
                                                                             Medicare Spending
                                                                                 per capita

                                                                    15,000




                                   Medicare spending per enrollee
                                                                    13,000


                                                                    11,000


                                                                    9,000


                                                                    7,000


                                                                    5,000
Rethinking health care
Spending – and supply sensitive care
                                                                Hospital and Physician Spending
                                                                      last 2 years of life at
           Inpatient + Part B spending per decedent               USN&WR top 10 hospitals


                                                      120,000

                                                                       UCLA Medical Center     72,793
                                                      100,000          New York-Presbyterian   69,962
 How can the best medical care in the world cost twice as much as
                                            Johns Hopkins       60,653
 the best medical care in the world?
            80,000                          UCSF Medical Center 56,859
                                                                         Uwe Reinhardt
                                                                       Univ. of Washington     50,716
                                                      60,000           Mass. General           47,880
                                                                       Barnes-Jewish           44,463
                                                                       Duke University Hosp.   37,765
                                                      40,000
                                                                       Mayo Clinic (St. Mary's) 37,271
                                                                       Cleveland Clinic        35,455
                                                      20,000
Rethinking health care
The Dartmouth Atlas of Health Care
                                     1.   What we know – 3 case studies
                                     2.   What I think we’ve learned
                                     3.   Translating evidence to policy
                                     4.   Is there reason for hope?
Preference Sensitive Care
Building the evidence: the Prostate Patient Outcome Research Team
Exploring the causes of variations in TURP for BPH
Interdisciplinary team; multiple methods
   Focus groups of urologists to determine clinical theories
     Preventive hypothesis: must operate early in a progressive disease
     Quality of life hypothesis

   Clinical research: decision-analysis, cohort studies
      No survival benefit from surgery
      Benefit of surgery depends upon patients’ values (symptoms vs sexual
         dysfunction)
      Patients’ values differed dramatically

Implications:
   Broadly applicable – orthopedics, cardiology, oncology, etc
   Need for accurate information on risks and benefits
   Structured approach to supporting informed patient choice
   Studies have now demonstrated effectiveness of decision aids
Preference Sensitive Care
Building the evidence: the Prostate PORT

Interdisciplinary team; multiple methods
   Focus groups of urologists to determine clinical theories
     Preventive hypothesis: must operate early in a progressive disease
     Quality of life hypothesis

   Clinical research: decision-analysis, cohort studies
      No survival benefit from surgery
      Benefit of surgery depends upon patients’ values (symptoms vs sexual
         dysfunction)
      Patients’ values differed dramatically

Implications:
   Broadly applicable – orthopedics, cardiology, oncology, etc
   Need for accurate information on risks and benefits
   Structured approach to supporting informed patient choice
   Studies have now demonstrated effectiveness of decision aids
Preference Sensitive Care
Translating evidence into policy

Underlying problems
   Inadequate information on risks and benefits of biologically targeted treatments
   Provider-dominated decision-making

Remedies
   Outcomes research (comparative effectiveness)
   Informed patient choice

Policy implications and progress
   Major investment in comparative effectiveness research
   National standards now include informed choice as core quality measure
   Many integrated delivery systems are moving to adopt shared decision-making
   States moving to require informed patient choice as legal standard
Safe and Effective care
Population: Patients undergoing Coronary Artery Bypass Graft
Providers: Cardiovascular surgery centers in New England


                                               Northern New England
                                               Cardiovascular Disease
                                                    Study Group

                                                 Origins: threatened public
                                                 report of unadjusted CABG
                              Eastern Maine      mortality rates
                              Medical Center
  Fletcher Allen
  Health Care
                                                 New England rates varied two
      Dartmouth         Maine
      Hitchcock         Medical                  fold: 3.1% to 6.3%
      Medical Center    Center

                                                 Surgeons agreed to collect
                   Concord Hospital              relevant clinical data
Safe and Effective care
Population: Patients undergoing Coronary Artery Bypass Graft
Providers: Cardiovascular surgery centers in New England

                                                         7

                                                         6



                            In-Hospital Mortality Rate
Adjusted mortality
no less variable:                                        5
  2.3% to 6.3%                                           4

Near death experience                                    3
of study group
                                                         2
Now over 20 years of                                     1
experience; 100+
papers published; all                                    0
sites still participating                                      1      2     3       4      5
in 3 meetings per year                                                    Center
                                                             O’Connor et al, JAMA, 1991;266:803-809
Safe and Effective Care
Improvement achieved as research advanced
                             6
                                                               Initial intervention-data feedback,
                                                               site visits and CQI training
                             5
        Mortality rate (%)




                             4


                             3


                             2        Mode of death study- low
                                      output heart failure major
                                                                        Process mapping
                                      cause of in-hospital
                             1                                          and identification
                                      mortality
                                                                        of high leverage
                                                                        areas
                             0
                                 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999
                                                               Year
Safe and Effective Care
Translating evidence into policy

Underlying problems
   Inadequate data: on patient attributes, process of care and outcomes
   Small numbers, lack of follow-up prevent learning
   Flawed professional model: individual responsibility and autonomy
Remedy
   Technical: registries to support ongoing study of variation in outcomes
     Define relevant local care system / teams (to allow comparison with others)
     Measure and compare processes and outcomes
   Cultural: create teams and systems capable of learning
     Engage clinicians in practice-based research and improvement
     Enable reflective practice – timely, relevant feedback
Policy implications and progress
   Potential benefits – to patients, physicians, managers and policy-makers -- of
     practice-based research networks is substantial
   Lack of government support remains challenge. Most efforts are voluntary, self-
     funded.
Variations in spending
Building the evidence base
                             “How can the best medical
                             care in the world cost twice
                             as much as the best medical
                             care in the world?
Variations in spending
  Building the evidence base

    Health implications of variations in spending
        Study population: Medicare patients with AMI, colon cancer, hip fracture
        Comparison: across (1) regions; (2) academic medical centers – grouped
          according to “intensity” – price and illness adjusted spending.
        Measures: content, quality and outcomes of care



Robert Wood Johnson Foundation
National Institute of Aging
California Healthcare Foundation
Aetna Foundation
Wellpoint Foundation
United Healthcare Foundation


(1) Fisher et al. Ann Intern Med: 2003; 138: 273-298
(2) Baicker et al. Health Affairs web exclusives, October 7, 2004
(3) Fisher et al. Health Affairs, web exclusives, Nov 16, 2005
(4) Skinner et al. Health Affairs web exclusives, Feb 7, 2006
(5) Sirovich et al Ann Intern Med: 2006; 144: 641-649
(6) Fowler et al. JAMA: 299: 2406-2412
What do they get more of?
Effective Care: benefit clear for all                              If bar on this side
  Reperfusion in 12 hours (Heart attack)                           higher spending
  Aspirin at admission (Heart attack)
                                                                   regions get more
  Mammogram, Women 65-69
  Pap Smear, Women 65+
  Pneumococcal Immunization (ever)

Preference Sensitive: values matter
  Total Hip Replacement
  Total Knee Replacement
  Back Surgery
  CABG following heart attack

Supply sensitive: often avoidable care
 Total Inpatient Days
 Inpatient Days in ICU or CCU
 Evaluation and Management (visits)
 Imaging
 Diagnostic Tests

                                                  0.5      1.00      1.5      2.0      2.5
                                     Ratio of rate in high spending to low spending regions
Outcomes and Quality
  High spending compared to low spending regions


                                                      Physician’s     Patient-Perceived
   Health Outcomes
                                                      Perceptions          Quality

                                                       Worse          Lower satisfaction
   No gain in survival
                                                    communication     with hospital care

                                                Greater difficulty     Worse access to
    No better function
                                              ensuring coordination     primary care

                                                 Greater perception   No sense that care
                                                    of scarcity           is rationed


(1) Fisher et al. Ann Intern Med: 2003; 138: 273-298
(2) Baicker et al. Health Affairs web exclusives, October 7, 2004
(3) Fisher et al. Health Affairs, web exclusives, Nov 16, 2005
(4) Skinner et al. Health Affairs web exclusives, Feb 7, 2006
(5) Sirovich et al Ann Intern Med: 2006; 144: 641-649
(6) Fowler et al. JAMA: 299: 2406-2412
The paradox of plenty
Pop Quiz….


If we cut spending so that all U.S. regions were receiving the
   same per-capita amount as the lowest spending regions,
   which of the following would apply:

1. U.S. healthcare spending would fall by 20% to 30%

2. The Medicare Trust Fund might survive a few years past it’s
   predicted collapse in 2017 (the year I become eligible).

3. We could send a third of the U.S. healthcare workforce to Africa and
   improve the health of both continents.

4. All of the above.
Variations in spending
What’s going on? General attributes of U.S. health care
   Assumption that more is better
   Inadequate information on risks and benefits
   Growing tension between science and professionalism --
    and -- market approach (health care as a commodity)
Variations in spending
What’s going on? Exploring causes of regional variations


     Patient
                             Malpractice
     Demand

                           Less than 10% of
  Little difference
                              difference
Variations in spending
What’s going on? Exploring causes of regional variations


     Patient
                             Malpractice           Supply & payment
     Demand

                           Less than 10% of
  Little difference                                 Powerful influence
                              difference

                                                    Explains less than
                                                    50% of difference
Variations in spending
What’s going on? Exploring causes of regional variations


     Patient
                                     Malpractice       Supply & payment
     Demand

                                    Less than 10% of
  Little difference 32%                     65%        Powerful influence
                                       difference
         4.0         higher    50         higher
                               40                      Explains less than
         3.0
                               30                      50% of difference
         2.0
                               20
         1.0
                               10

   Regional
   Spending     Low High              Low High
               Hospital Beds    Medical Specialists
Variations in spending
What’s going on? Exploring causes of regional variations


     Patient
                             Malpractice           Supply & payment
     Demand

                           Less than 10% of
  Little difference                                 Powerful influence
                              difference

                                                    Explains less than
                                                    50% of difference
Variations in spending
 What’s going on? Exploring causes of regional variations


        Patient
                              Malpractice           Supply & payment
        Demand

                            Less than 10% of
    Little difference                                Powerful influence
                               difference

                                                     Explains less than
                                                     50% of difference




New York Times
August 18, 2006
Variations in spending
What’s going on? Exploring causes of regional variations


     Patient
                             Malpractice           Supply & payment
     Demand

                           Less than 10% of
  Little difference                                 Powerful influence
                              difference

                                                    Explains less than
                                                    50% of difference
Variations in spending
Exploring causes -- gray area decisions

Evidence-based decisions – drawn from guidelines
Doctors sometimes disagreed – but was unrelated to regional
differences in spending

Gray area decisions (more judgment required):
For a patient with well-controlled high blood pressure and no other
medical problems, when would you schedule the next visit?
Variations in spending
 Exploring causes -- gray area decisions
Clinical evidence is an important -- but limited --
influence on clinical decision-making.
                                                                Policy Environment
Physicians practice within a local organizational
                                                              (e.g. payment system)
context that profoundly influences their decision-making.
Payment system ensures that existing capacity
is fully utilized. Physicians adapt to available resources:
more referrals, more admissions, more ICU stays
                                                                       Local
                                                              Organizational Context
Consequence: reasonable individual clinical and local         (e.g. capacity - culture)
decisions lead, in aggregate, to higher utilization rates,
greater costs -- and inadvertently -- worse outcomes

The more complicated care
becomes, the more likely
                                          Clinical            Physician - Patient
mistakes are to occur.
                                          Evidence               Encounter
Hospitals are dangerous places if         Professionalism
you don’t need to be there.
Culture? Capacity? Both?
Differences in spending and practice across top academic centers

           Medicare beneficiaries with chronic illness, 2001-2005
Variations in spending
Exploring causes: case studies beginning to shed light




                         2006 Spending 92-06 Growth
            McAllen $14,946          8.3%
            La Crosse        $5,812        3.9%
Variations in spending
Exploring causes: case studies beginning to shed light

                                   “Here … a medical community came to
                                   treat patients the way subprime mortgage
                                   lenders treated home buyers: as profit
                                   centers.”
                                                             Atul Gawande

                         2006 Spending 92-06 Growth
            McAllen $14,946          8.3%
            La Crosse        $5,812        3.9%
Variations in spending
Exploring causes: case studies beginning to shed light

                                    “Here … a medical community came to
                                    treat patients the way subprime mortgage
                                    lenders treated home buyers: as profit
                                    centers.”
                                                              Atul Gawande

                            2006 Spending 92-06 Growth
               McAllen $14,946          8.3%
               La Crosse        $5,812        3.9%


 “…a culture that focuses on
the wellbeing of the
community, not just the
financial health of our system.”

     Jeff Thompson, MD
     CEO Gunderson-Lutheran
              La Crosse, WI
What I think we know
Putting the pieces together: the IOM system of effect


    La Crosse                                                               McAllen
                                       Aims




                Micro-system                        Organization
               How care is provided               e.g. capacity, policies
                 to each patient                    practices, norms




                                  Environment
                               e,g, payment, regulations
                                  measures, culture




Institute of Medicine: Crossing the Quality Chasm
41

 What I think we know
 Underlying problems – and principles to guide reform

Underlying problem                     Key principles
Confusion about aims – what            Clarify aims: Better health, better care
we’re trying to produce                lower costs

Bad data allow MDs to discount it,     Better information that engages
and public to assume that medicine     physicians, creates tension for change,
is science and that more is better.    supports improvement; informs consumers

Flawed conceptual model. Health        New model: It’s the system. Establish
is produced by individual actions of   teams and organizations accountable for
“good” clinicians, working hard.       aims and capable of improving practice

Wrong incentives reinforce model,      Rethink our incentives: Realign
reward fragmentation, induce more      incentives – both financial and
care and entrepreneurial behavior.     professional – with aims.
Translating evidence to policy
Aims and Performance Measurement

Emerging alignment on aims: National Priorities Partners
  Improving population health
  Improving safety & reliability and coordination of care
  Engaging patients in managing their care and making informed decisions
  Eliminating overuse

Performance measurement: the critical lever
  National Quality Forum “Episode measurement framework”
  Key notions
    Core question: how did the patient do over the relevant time-course?
    Value: best judged from the patient’s perspective; is multidimensional
    Requires organizational accountability – over time
Translating evidence to policy
Performance Measurement – across episodes

                                                                                             Post AMI Trajectory 1 (T1)
                                                                                             Relatively healthy adult
                                Assessment of
                                 Preferences                                                 Focus on:
                                                                                             • Quality of Life
                                                                                             • Functional Status
        Population at Risk
                                                                                             • 20 Prevention Strategies
         10 Prevention                                                                       • Rehabilitation
         (no known CAD)                                                                      • Advanced care planning
                                                  Post Acute/
         20 Prevention             Acute
                                                  Rehabilitation      20 Prevention
         (CAD no prior AMI)        Phase
                                                  Phase

    20 Prevention
    (CAD with prior AMI)           PHASE 2            PHASE 3              PHASE 4           Post AMI Trajectory 2 (T2)
    Advanced Care Planning                                                                   Adult with multiple co-morbidities

              PHASE 1                                                                        Focus on:
                                                                                             • Quality of Life
                                                  Living w/ Illness/Disability (T1)          • Functional Status
         Staying Healthy        Getting Better
                                                    Coping w/ End of Life (T2)               • 20 Prevention Strategies
                                                                                             • Advanced Care Planning
               Traditional model                                         Needed model        • Advanced Directives
                                                                                             • Palliative Care/Symptom Control
                   Autonomy                                             Accountability
            Individual Responsibility
                         Episode begins –                            Shared Episode ends –
                                                                            Responsibility
                              onset of symptoms                                       1 year post AMI
© NQF
Translating evidence to policy
Implications for Health Information Technology

Effective registries are thus critical for a learning health system
To learn -- we need to know:
   Patient attributes and risks (including biologic markers)
   Specific targeted biologic interventions performed
   Attributes of system -- delivery methods -- where care provided
   Health outcomes, patient experience and costs
Infrastructure would support
   Comparative effectiveness research: compare biologic and delivery
     system interventions, controlling for patient and local attributes.
   Comparative performance assessment: compare providers and local
     systems, controlling for patient attributes
Both are critical
Translating evidence to policy
  Organizational Accountability and Payment Reforms

    Accountable Care Organizations

    Principles:
        Establish provider organizations that can effectively manage the full
          continuum of care as a real or virtually integrated local delivery system
        Performance measurement – to support improvement and accountability
        Payment reform: establish target spending levels; shared savings

    Potential ACOs
        Integrated delivery systems (Kaiser-Permanente, Group Health)
        Physician Networks; Hospital that employ primary care physicians
        Insight from research:
           Most physicians already practice within coherent local networks
           Performance measurement at group level feasible
           Feasible to develop spending targets for most U.S. networks
Fisher et al. Creating Accountable Care Organizations, Health
Affairs 26(1) 2007:w44-w57.
Translating evidence to policy
Organizational Accountability and Payment Reforms

Early pilots promising; many organizations supportive
   Physician Group Practice demonstration successful
   Congressional Budget Office scored as cost-saving
   Support from key stakeholders has solidified

ACOs accepted as component of current bills
   Support for extensive pilots, rapid expansion in House bills
   Senate Finance – voluntary program (not pilot) by 2012

Initiatives at state and local level
   Brookings-Dartmouth supporting pilot development in multiple sites
   Pilots to start January 2010 in two (or more) sites (VA, KY, TX)
   Learning collaborative underway with 40+ health systems
   Massachusetts, Vermont, others moving forward
Rethinking health care
The Dartmouth Atlas of Health Care
                                     1.   What we know – 3 stories
                                     2.   What I think I know
                                     3.   From insight to action
                                     4.   Is there reason for hope?
48

Is there reason for hope?
Theories of change – can they help frame our thinking

Health care is a complex adaptive system
   Autonomous actors continuously adapt their behavior
   System held in place by “attractors”, self-reinforcing behaviors
Change in complex systems occurs through:
   Exploring variation and paradox to create a tension for change;
   Creating better alternatives (better policies, better models of care)
   Supporting interaction and learning – so others can see new ways to go
   New attractors (performance measurement, payment, positive deviants)
Implications for research – and policy
   Public reporting: creates a tension for change, raises good questions
   Policy relevant research: has undermined flawed assumptions;
     suggested path toward reform
   Registries, practice networks, have developed evidence, engaged
     clinicians, engaged local systems and communities
Is there reason for hope?
Theories of change – have stimulated new conversations




 “How do they do that?”                Common themes
      conference                       Shared aims, accountable to community
Everett, WA          Portland, ME      Strong foundation of primary care
Sacramento, CA       Sayre, PA
La Crosse, WI        Richmond, VA
                                       Physician engagement as leaders
Cedar Rapids, IA     Asheville, NC     Organizational support important
Temple, TX           Tallahassee, FL
                                       Use of data to drive change
 Lighter colors = lower spending
Is there reason for hope?
Theories of change – have stimulated new conversations




 “How do they do that?”                Common themes
      conference                       Shared aims, accountable to community
Everett, WA          Portland, ME      Physician engagement as leaders
Sacramento, CA       Sayre, PA
La Crosse, WI        Richmond, VA
                                       Strong foundation of primary care
Cedar Rapids, IA     Asheville, NC     Organizational support important
Temple, TX           Tallahassee, FL
                                       Use of data to drive change
 Lighter colors = lower spending       High self-efficacy; high morale
Have we made a difference?


                Trends in important things
                     in U.S. healthcare
                    uninsured, spending




         1973                                2009


                1983
Have we made a difference?


               Trends in important things
                    in U.S. healthcare
            insights, evidence, tests of change




         1973                                     2009


                1983
54

 Have we made a difference?
 Exploring variation has helped to advance knowledge and policy

Underlying problem                     Key principles
Confusion about aims – what            Clarify aims: Better health, better care
we’re trying to produce                lower costs

Bad data allow MDs to discount it,     Better information that engages
and public to assume that medicine     physicians, creates tension for change,
is science and that more is better.    supports improvement; informs consumers

Flawed conceptual model. Health        New model: It’s the system. Establish
is produced by individual actions of   teams and organizations accountable for
“good” clinicians, working hard.       aims and capable of improving practice

Wrong incentives reinforce model,      Rethink our incentives: Realign
reward fragmentation, induce more      incentives – both financial and
care and entrepreneurial behavior.     professional – with aims. Question pay
                                       for performance.

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Elliott Fisher | Monitoring Variation in Health Care

  • 1. Welcome to the 5th HARC Forum Monitoring variation in healthcare quality - an evidence base to improve healthcare HARC is a as a partnership between the Sax Institute, Clinical Excellence Commission and the Greater Metropolitan Clinical Taskforce
  • 2. Keynote Speaker Professor Elliott Fisher Professor of Community and Family Medicine at Dartmouth Medical School and Director of the Center for Health Policy Research at the Dartmouth Institute for Health Policy and Clinical Practice US Dartmouth Atlas of Health Care Project - monitoring and explaining variation in healthcare to improve the health system
  • 3. Monitoring Variation in Health Care: An approach to improving the evidence base for practice and policy Elliott S. Fisher, MD, MPH Professor of Medicine and Community and Family Medicine Dartmouth Medical School Director for Population Health and Policy The Dartmouth Institute for Health Policy and Clinical Practice
  • 4. Houston, we’ve got a problem… The usual suspects: Rising costs Uneven quality Declining access to care Some looming challenges Loss of professional authority of physicians Integrity and relevance of academic medicine
  • 5. Houston, we’ve got a problem… Traditional diagnoses: Prescriptions: A shortage of money Spend more A shortage of doctors Train more A shortage of economists Focus on prices Every system is perfectly designed to get the results that it achieves Paul Batalden Insanity: doing the same thing day after day and expecting different results Einstein
  • 6. Rethinking health care Origins of the Dartmouth Institute – and Dartmouth Atlas Project Science, December 14, 1973; Volume 182, pp 1102-08
  • 7. Rethinking health care A simple analytic framework; a shared vision Application of epidemiologic methods to health care services Define population at risk Define events Examine variations across relevant systems -- providers Ask good questions Organizational Development Independent institute within Medical School Interdisciplinary research group; all with departmental appointments Governance through a shared vision: Exploring the causes and consequences of unwarranted variations Commitment to making a difference (locally, regionally, nationally) Major long-term funding helps maintain focus
  • 8. Rethinking health care The Dartmouth Atlas of Health Care Methods: Population at risk – over 65 Compare Hospital Referral Regions Events of interest -- many
  • 9. Rethinking health care The Dartmouth Atlas of Health Care Categories of care Safe and effective care Preference sensitive care Supply-sensitive care
  • 10. Rethinking health care Preference-sensitive care Transurethral Prostatectomy for Benign Prostatic Hypertrophy per 1000 15.0 13.0 TURP for BPH 11.0 9.0 7.0 5.0 3.0
  • 11. Rethinking health care Safe and Effective Care 30 Day Mortality Following CABG 30-Day Mortality Following CABG (%) 12.0 10.0 8.0 6.0 4.0 2.0
  • 12. Rethinking health care Spending – and supply sensitive care Medicare Spending per capita 15,000 Medicare spending per enrollee 13,000 11,000 9,000 7,000 5,000
  • 13. Rethinking health care Spending – and supply sensitive care Hospital and Physician Spending last 2 years of life at Inpatient + Part B spending per decedent USN&WR top 10 hospitals 120,000 UCLA Medical Center 72,793 100,000 New York-Presbyterian 69,962 How can the best medical care in the world cost twice as much as Johns Hopkins 60,653 the best medical care in the world? 80,000 UCSF Medical Center 56,859 Uwe Reinhardt Univ. of Washington 50,716 60,000 Mass. General 47,880 Barnes-Jewish 44,463 Duke University Hosp. 37,765 40,000 Mayo Clinic (St. Mary's) 37,271 Cleveland Clinic 35,455 20,000
  • 14. Rethinking health care The Dartmouth Atlas of Health Care 1. What we know – 3 case studies 2. What I think we’ve learned 3. Translating evidence to policy 4. Is there reason for hope?
  • 15. Preference Sensitive Care Building the evidence: the Prostate Patient Outcome Research Team Exploring the causes of variations in TURP for BPH Interdisciplinary team; multiple methods Focus groups of urologists to determine clinical theories Preventive hypothesis: must operate early in a progressive disease Quality of life hypothesis Clinical research: decision-analysis, cohort studies No survival benefit from surgery Benefit of surgery depends upon patients’ values (symptoms vs sexual dysfunction) Patients’ values differed dramatically Implications: Broadly applicable – orthopedics, cardiology, oncology, etc Need for accurate information on risks and benefits Structured approach to supporting informed patient choice Studies have now demonstrated effectiveness of decision aids
  • 16. Preference Sensitive Care Building the evidence: the Prostate PORT Interdisciplinary team; multiple methods Focus groups of urologists to determine clinical theories Preventive hypothesis: must operate early in a progressive disease Quality of life hypothesis Clinical research: decision-analysis, cohort studies No survival benefit from surgery Benefit of surgery depends upon patients’ values (symptoms vs sexual dysfunction) Patients’ values differed dramatically Implications: Broadly applicable – orthopedics, cardiology, oncology, etc Need for accurate information on risks and benefits Structured approach to supporting informed patient choice Studies have now demonstrated effectiveness of decision aids
  • 17. Preference Sensitive Care Translating evidence into policy Underlying problems Inadequate information on risks and benefits of biologically targeted treatments Provider-dominated decision-making Remedies Outcomes research (comparative effectiveness) Informed patient choice Policy implications and progress Major investment in comparative effectiveness research National standards now include informed choice as core quality measure Many integrated delivery systems are moving to adopt shared decision-making States moving to require informed patient choice as legal standard
  • 18. Safe and Effective care Population: Patients undergoing Coronary Artery Bypass Graft Providers: Cardiovascular surgery centers in New England Northern New England Cardiovascular Disease Study Group Origins: threatened public report of unadjusted CABG Eastern Maine mortality rates Medical Center Fletcher Allen Health Care New England rates varied two Dartmouth Maine Hitchcock Medical fold: 3.1% to 6.3% Medical Center Center Surgeons agreed to collect Concord Hospital relevant clinical data
  • 19. Safe and Effective care Population: Patients undergoing Coronary Artery Bypass Graft Providers: Cardiovascular surgery centers in New England 7 6 In-Hospital Mortality Rate Adjusted mortality no less variable: 5 2.3% to 6.3% 4 Near death experience 3 of study group 2 Now over 20 years of 1 experience; 100+ papers published; all 0 sites still participating 1 2 3 4 5 in 3 meetings per year Center O’Connor et al, JAMA, 1991;266:803-809
  • 20. Safe and Effective Care Improvement achieved as research advanced 6 Initial intervention-data feedback, site visits and CQI training 5 Mortality rate (%) 4 3 2 Mode of death study- low output heart failure major Process mapping cause of in-hospital 1 and identification mortality of high leverage areas 0 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 Year
  • 21. Safe and Effective Care Translating evidence into policy Underlying problems Inadequate data: on patient attributes, process of care and outcomes Small numbers, lack of follow-up prevent learning Flawed professional model: individual responsibility and autonomy Remedy Technical: registries to support ongoing study of variation in outcomes Define relevant local care system / teams (to allow comparison with others) Measure and compare processes and outcomes Cultural: create teams and systems capable of learning Engage clinicians in practice-based research and improvement Enable reflective practice – timely, relevant feedback Policy implications and progress Potential benefits – to patients, physicians, managers and policy-makers -- of practice-based research networks is substantial Lack of government support remains challenge. Most efforts are voluntary, self- funded.
  • 22. Variations in spending Building the evidence base “How can the best medical care in the world cost twice as much as the best medical care in the world?
  • 23. Variations in spending Building the evidence base Health implications of variations in spending Study population: Medicare patients with AMI, colon cancer, hip fracture Comparison: across (1) regions; (2) academic medical centers – grouped according to “intensity” – price and illness adjusted spending. Measures: content, quality and outcomes of care Robert Wood Johnson Foundation National Institute of Aging California Healthcare Foundation Aetna Foundation Wellpoint Foundation United Healthcare Foundation (1) Fisher et al. Ann Intern Med: 2003; 138: 273-298 (2) Baicker et al. Health Affairs web exclusives, October 7, 2004 (3) Fisher et al. Health Affairs, web exclusives, Nov 16, 2005 (4) Skinner et al. Health Affairs web exclusives, Feb 7, 2006 (5) Sirovich et al Ann Intern Med: 2006; 144: 641-649 (6) Fowler et al. JAMA: 299: 2406-2412
  • 24. What do they get more of? Effective Care: benefit clear for all If bar on this side Reperfusion in 12 hours (Heart attack) higher spending Aspirin at admission (Heart attack) regions get more Mammogram, Women 65-69 Pap Smear, Women 65+ Pneumococcal Immunization (ever) Preference Sensitive: values matter Total Hip Replacement Total Knee Replacement Back Surgery CABG following heart attack Supply sensitive: often avoidable care Total Inpatient Days Inpatient Days in ICU or CCU Evaluation and Management (visits) Imaging Diagnostic Tests 0.5 1.00 1.5 2.0 2.5 Ratio of rate in high spending to low spending regions
  • 25. Outcomes and Quality High spending compared to low spending regions Physician’s Patient-Perceived Health Outcomes Perceptions Quality Worse Lower satisfaction No gain in survival communication with hospital care Greater difficulty Worse access to No better function ensuring coordination primary care Greater perception No sense that care of scarcity is rationed (1) Fisher et al. Ann Intern Med: 2003; 138: 273-298 (2) Baicker et al. Health Affairs web exclusives, October 7, 2004 (3) Fisher et al. Health Affairs, web exclusives, Nov 16, 2005 (4) Skinner et al. Health Affairs web exclusives, Feb 7, 2006 (5) Sirovich et al Ann Intern Med: 2006; 144: 641-649 (6) Fowler et al. JAMA: 299: 2406-2412
  • 26. The paradox of plenty Pop Quiz…. If we cut spending so that all U.S. regions were receiving the same per-capita amount as the lowest spending regions, which of the following would apply: 1. U.S. healthcare spending would fall by 20% to 30% 2. The Medicare Trust Fund might survive a few years past it’s predicted collapse in 2017 (the year I become eligible). 3. We could send a third of the U.S. healthcare workforce to Africa and improve the health of both continents. 4. All of the above.
  • 27. Variations in spending What’s going on? General attributes of U.S. health care Assumption that more is better Inadequate information on risks and benefits Growing tension between science and professionalism -- and -- market approach (health care as a commodity)
  • 28. Variations in spending What’s going on? Exploring causes of regional variations Patient Malpractice Demand Less than 10% of Little difference difference
  • 29. Variations in spending What’s going on? Exploring causes of regional variations Patient Malpractice Supply & payment Demand Less than 10% of Little difference Powerful influence difference Explains less than 50% of difference
  • 30. Variations in spending What’s going on? Exploring causes of regional variations Patient Malpractice Supply & payment Demand Less than 10% of Little difference 32% 65% Powerful influence difference 4.0 higher 50 higher 40 Explains less than 3.0 30 50% of difference 2.0 20 1.0 10 Regional Spending Low High Low High Hospital Beds Medical Specialists
  • 31. Variations in spending What’s going on? Exploring causes of regional variations Patient Malpractice Supply & payment Demand Less than 10% of Little difference Powerful influence difference Explains less than 50% of difference
  • 32. Variations in spending What’s going on? Exploring causes of regional variations Patient Malpractice Supply & payment Demand Less than 10% of Little difference Powerful influence difference Explains less than 50% of difference New York Times August 18, 2006
  • 33. Variations in spending What’s going on? Exploring causes of regional variations Patient Malpractice Supply & payment Demand Less than 10% of Little difference Powerful influence difference Explains less than 50% of difference
  • 34. Variations in spending Exploring causes -- gray area decisions Evidence-based decisions – drawn from guidelines Doctors sometimes disagreed – but was unrelated to regional differences in spending Gray area decisions (more judgment required): For a patient with well-controlled high blood pressure and no other medical problems, when would you schedule the next visit?
  • 35. Variations in spending Exploring causes -- gray area decisions Clinical evidence is an important -- but limited -- influence on clinical decision-making. Policy Environment Physicians practice within a local organizational (e.g. payment system) context that profoundly influences their decision-making. Payment system ensures that existing capacity is fully utilized. Physicians adapt to available resources: more referrals, more admissions, more ICU stays Local Organizational Context Consequence: reasonable individual clinical and local (e.g. capacity - culture) decisions lead, in aggregate, to higher utilization rates, greater costs -- and inadvertently -- worse outcomes The more complicated care becomes, the more likely Clinical Physician - Patient mistakes are to occur. Evidence Encounter Hospitals are dangerous places if Professionalism you don’t need to be there.
  • 36. Culture? Capacity? Both? Differences in spending and practice across top academic centers Medicare beneficiaries with chronic illness, 2001-2005
  • 37. Variations in spending Exploring causes: case studies beginning to shed light 2006 Spending 92-06 Growth McAllen $14,946 8.3% La Crosse $5,812 3.9%
  • 38. Variations in spending Exploring causes: case studies beginning to shed light “Here … a medical community came to treat patients the way subprime mortgage lenders treated home buyers: as profit centers.” Atul Gawande 2006 Spending 92-06 Growth McAllen $14,946 8.3% La Crosse $5,812 3.9%
  • 39. Variations in spending Exploring causes: case studies beginning to shed light “Here … a medical community came to treat patients the way subprime mortgage lenders treated home buyers: as profit centers.” Atul Gawande 2006 Spending 92-06 Growth McAllen $14,946 8.3% La Crosse $5,812 3.9% “…a culture that focuses on the wellbeing of the community, not just the financial health of our system.” Jeff Thompson, MD CEO Gunderson-Lutheran La Crosse, WI
  • 40. What I think we know Putting the pieces together: the IOM system of effect La Crosse McAllen Aims Micro-system Organization How care is provided e.g. capacity, policies to each patient practices, norms Environment e,g, payment, regulations measures, culture Institute of Medicine: Crossing the Quality Chasm
  • 41. 41 What I think we know Underlying problems – and principles to guide reform Underlying problem Key principles Confusion about aims – what Clarify aims: Better health, better care we’re trying to produce lower costs Bad data allow MDs to discount it, Better information that engages and public to assume that medicine physicians, creates tension for change, is science and that more is better. supports improvement; informs consumers Flawed conceptual model. Health New model: It’s the system. Establish is produced by individual actions of teams and organizations accountable for “good” clinicians, working hard. aims and capable of improving practice Wrong incentives reinforce model, Rethink our incentives: Realign reward fragmentation, induce more incentives – both financial and care and entrepreneurial behavior. professional – with aims.
  • 42. Translating evidence to policy Aims and Performance Measurement Emerging alignment on aims: National Priorities Partners Improving population health Improving safety & reliability and coordination of care Engaging patients in managing their care and making informed decisions Eliminating overuse Performance measurement: the critical lever National Quality Forum “Episode measurement framework” Key notions Core question: how did the patient do over the relevant time-course? Value: best judged from the patient’s perspective; is multidimensional Requires organizational accountability – over time
  • 43. Translating evidence to policy Performance Measurement – across episodes Post AMI Trajectory 1 (T1) Relatively healthy adult Assessment of Preferences Focus on: • Quality of Life • Functional Status Population at Risk • 20 Prevention Strategies 10 Prevention • Rehabilitation (no known CAD) • Advanced care planning Post Acute/ 20 Prevention Acute Rehabilitation 20 Prevention (CAD no prior AMI) Phase Phase 20 Prevention (CAD with prior AMI) PHASE 2 PHASE 3 PHASE 4 Post AMI Trajectory 2 (T2) Advanced Care Planning Adult with multiple co-morbidities PHASE 1 Focus on: • Quality of Life Living w/ Illness/Disability (T1) • Functional Status Staying Healthy Getting Better Coping w/ End of Life (T2) • 20 Prevention Strategies • Advanced Care Planning Traditional model Needed model • Advanced Directives • Palliative Care/Symptom Control Autonomy Accountability Individual Responsibility Episode begins – Shared Episode ends – Responsibility onset of symptoms 1 year post AMI © NQF
  • 44. Translating evidence to policy Implications for Health Information Technology Effective registries are thus critical for a learning health system To learn -- we need to know: Patient attributes and risks (including biologic markers) Specific targeted biologic interventions performed Attributes of system -- delivery methods -- where care provided Health outcomes, patient experience and costs Infrastructure would support Comparative effectiveness research: compare biologic and delivery system interventions, controlling for patient and local attributes. Comparative performance assessment: compare providers and local systems, controlling for patient attributes Both are critical
  • 45. Translating evidence to policy Organizational Accountability and Payment Reforms Accountable Care Organizations Principles: Establish provider organizations that can effectively manage the full continuum of care as a real or virtually integrated local delivery system Performance measurement – to support improvement and accountability Payment reform: establish target spending levels; shared savings Potential ACOs Integrated delivery systems (Kaiser-Permanente, Group Health) Physician Networks; Hospital that employ primary care physicians Insight from research: Most physicians already practice within coherent local networks Performance measurement at group level feasible Feasible to develop spending targets for most U.S. networks Fisher et al. Creating Accountable Care Organizations, Health Affairs 26(1) 2007:w44-w57.
  • 46. Translating evidence to policy Organizational Accountability and Payment Reforms Early pilots promising; many organizations supportive Physician Group Practice demonstration successful Congressional Budget Office scored as cost-saving Support from key stakeholders has solidified ACOs accepted as component of current bills Support for extensive pilots, rapid expansion in House bills Senate Finance – voluntary program (not pilot) by 2012 Initiatives at state and local level Brookings-Dartmouth supporting pilot development in multiple sites Pilots to start January 2010 in two (or more) sites (VA, KY, TX) Learning collaborative underway with 40+ health systems Massachusetts, Vermont, others moving forward
  • 47. Rethinking health care The Dartmouth Atlas of Health Care 1. What we know – 3 stories 2. What I think I know 3. From insight to action 4. Is there reason for hope?
  • 48. 48 Is there reason for hope? Theories of change – can they help frame our thinking Health care is a complex adaptive system Autonomous actors continuously adapt their behavior System held in place by “attractors”, self-reinforcing behaviors Change in complex systems occurs through: Exploring variation and paradox to create a tension for change; Creating better alternatives (better policies, better models of care) Supporting interaction and learning – so others can see new ways to go New attractors (performance measurement, payment, positive deviants) Implications for research – and policy Public reporting: creates a tension for change, raises good questions Policy relevant research: has undermined flawed assumptions; suggested path toward reform Registries, practice networks, have developed evidence, engaged clinicians, engaged local systems and communities
  • 49. Is there reason for hope? Theories of change – have stimulated new conversations “How do they do that?” Common themes conference Shared aims, accountable to community Everett, WA Portland, ME Strong foundation of primary care Sacramento, CA Sayre, PA La Crosse, WI Richmond, VA Physician engagement as leaders Cedar Rapids, IA Asheville, NC Organizational support important Temple, TX Tallahassee, FL Use of data to drive change Lighter colors = lower spending
  • 50.
  • 51. Is there reason for hope? Theories of change – have stimulated new conversations “How do they do that?” Common themes conference Shared aims, accountable to community Everett, WA Portland, ME Physician engagement as leaders Sacramento, CA Sayre, PA La Crosse, WI Richmond, VA Strong foundation of primary care Cedar Rapids, IA Asheville, NC Organizational support important Temple, TX Tallahassee, FL Use of data to drive change Lighter colors = lower spending High self-efficacy; high morale
  • 52. Have we made a difference? Trends in important things in U.S. healthcare uninsured, spending 1973 2009 1983
  • 53. Have we made a difference? Trends in important things in U.S. healthcare insights, evidence, tests of change 1973 2009 1983
  • 54. 54 Have we made a difference? Exploring variation has helped to advance knowledge and policy Underlying problem Key principles Confusion about aims – what Clarify aims: Better health, better care we’re trying to produce lower costs Bad data allow MDs to discount it, Better information that engages and public to assume that medicine physicians, creates tension for change, is science and that more is better. supports improvement; informs consumers Flawed conceptual model. Health New model: It’s the system. Establish is produced by individual actions of teams and organizations accountable for “good” clinicians, working hard. aims and capable of improving practice Wrong incentives reinforce model, Rethink our incentives: Realign reward fragmentation, induce more incentives – both financial and care and entrepreneurial behavior. professional – with aims. Question pay for performance.