4. History
• Christiaan Eijkman was a Dutch physician and professor of
physiology whose demonstration that beriberi is caused by poor
diet led to the discovery of antineuritic vitamins.
• Together with Sir Frederick Hopkins, he received the Nobel Prize for
Physiology or Medicine in 1929 for the discovery of vitamins.
Sir Frederick Hopkins
https://images.app.goo.gl/2ZHVebh5XLMhYHCG7
Christiaan Eijkman
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Casimir Funk
‘Vitamine’ was coined in 1911 by Polish chemist Casimir Funk.
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Adolf Windaus
• Adolf Windaus (Nobel prize, 1928) elucidated the structure of the vitamin.
https://images.app.goo.gl/zTz7BBaNp9CzmTVz8
5. Introduction
Vitamins may be regarded as organic compounds required in
the diet in small amounts to perform specific biological
functions for normal maintenance of optimum growth and
health of the organism.
https://images.app.goo.gl/NFkmnmnXHWqcUvdy8
E.coli does not require any vitamin, as it can synthesize all of
them.
https://images.app.goo.gl/KMXnR9yMqHrUEM9F9
It is believed that during the course of evolution, the ability to
synthesize vitamins was lost. Hence, the higher organisms have
to obtain them from diet
The vitamins are required in small amounts, since their
degradation is relatively slow
6. Source: Satyanarayana, U. (2013). Biochemistry (4th ed.).
Classification of vitamins
There are about 13 vitamins, essential for humans. They are classified as fat soluble (A,
D, E and K) and water soluble (C and B-group) vitamins as shown in the below figure.
1
2
3
6
5
4
3
2
1
1
4
1
2
7. Vitamins are grouped into two categories:
❑Fat-soluble vitamins
are stored in the body's
liver, fatty tissue, and
muscles.
❑The four fat-soluble
vitamins are vitamins A,
D, E, and K.
❑These vitamins are
absorbed more easily
by the body in the
presence of dietary fat.
❑ Water-soluble vitamins are not stored in the
body.
❑ The nine water-soluble vitamins are vitamin C
and all the B vitamins.
❑ Any leftover or excess amounts of these leave
the body through the urine.
❑ They have to be consumed on a regular basis to
prevent shortages or deficiencies in the body.
❑ The exception to this is vitamin B12, which can
be stored in the liver for many years.
8. Difference Between
Water Soluble And Fat Soluble Vitamins
Water-Soluble Vitamins Fat-Soluble Vitamins
Meaning
As the name states – vitamins that can
dissolve in water are called water-soluble
vitamins
Similarly, vitamins that dissolve in fat are
called fat-soluble vitamins
Example
Vitamin B, C Vitamin A, D, E, K
Site of Absorption
Small intestine Small intestine
Affinity to Water
Hydrophilic Hydrophobic
9. Difference Between
Water Soluble And Fat Soluble Vitamins
Water-Soluble Vitamins Fat-Soluble Vitamins
How Body Handles Excess
Excess vitamins are excreted by the kidney Excess is stored in the body’s fatty tissues
Transportation
Travels freely in the bloodstream
Many vitamins require carriers (proteins) to
travel in the blood
Toxicity
Low toxicity Comparatively more toxic
Deficiency
Symptoms appear rather quickly Symptoms take time to manifest
10. Function
•Vitamin D is also known as the "sunshine vitamin," since it is made by the body after being in the
sun.
• Ten to 15 minutes of sunshine 3 times a week is enough to produce the body's requirement of vitamin
D for most people at most latitudes.
• People who do not live in sunny places may not make enough vitamin D. It is very hard to get enough
vitamin D from food sources alone.
• Vitamin D helps the body absorb calcium.
• You need calcium for the normal development and maintenance of healthy teeth and bones. It also
helps maintain proper blood levels of calcium and phosphorus.
https://images.app.goo.gl/9dA7NWN2TvDDxe3L6
•Vitamin A helps form and maintain healthy teeth, skeletal and soft tissue, mucus membranes, and skin.
• It is also known as retinol because it produces the pigments in the retina of the eye.
• Vitamin A promotes good eyesight, especially in low light. It also has a role in healthy pregnancy and
breastfeeding.
https://images.app.goo.gl/e41EfbbugvHMvZYDA
11. Function
•Vitamin E is an antioxidant also known as tocopherol.
•It helps the body form red blood cells and use vitamin K.
https://images.app.goo.gl/W4cAjFCs7CRbEfiY9
•Vitamin K is needed because without it, blood would not stick
together (coagulate). Some studies suggest that it is important for
bone health.
https://images.app.goo.gl/5q7Ucu8F6sEW6qkF8
alpha-Tocopherol C29H50O2
https://images.app.goo.gl/jRnnfXzMYRDEZHRNA
https://images.app.goo.gl/NJ4TtcASrdoHfGZr8
12. Function
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• Vitamin B1 (Thiamine) helps the body cells change carbohydrates into energy.
• Getting enough carbohydrates is very important during pregnancy and
breastfeeding.
• It is also essential for heart function and healthy nerve cells.
https://images.app.goo.gl/LBo2qgMxJBPXCgM27
https://images.app.goo.gl/Bn2xco3T72uf77Mp8
• Vitamin B2 (Riboflavin) works with the other B vitamins.
• It is important for body growth and the production of red blood cells.
https://images.app.goo.gl/tb5vnuT7Tf8CKcZ99
13. Function
• Vitamin B5 (Pantothenic acid) is essential for the metabolism of food.
• It also plays a role in the production of hormones and cholesterol.
https://images.app.goo.gl/nraSAQh6EpxnwJZMA
https://images.app.goo.gl/2iUS1srej5QV4Cuo9
•Vitamin B3 (Niacin) is a B vitamin that helps maintain healthy skin and nerves.
• It also has cholesterol-lowering effects at higher doses.
• It is also important for changing food to energy.
https://images.app.goo.gl/QC597aM9VFx1EZBe7
https://images.app.goo.gl/F16HyYaNCZhD6wq16 https://images.app.goo.gl/popQzhhh5VsEbas79
14. Function
•Vitamin B6 is also called pyridoxine.
• Vitamin B6 helps form red blood cells and maintain brain function.
• This vitamin also plays an important role in the proteins that are part of many
chemical reactions in the body.
• The more protein you eat the more pyridoxine your body requires.
https://images.app.goo.gl/A2bEKHx2RCHQ46486
https://images.app.goo.gl/CiXttdQsLTRKAqFr8
•Vitamin B7 (Biotin) is essential for the metabolism of proteins and
carbohydrates, and in the production of hormones and cholesterol.
https://images.app.goo.gl/hVLSqaAKrMYDcufF6
https://images.app.goo.gl/SQRovgghh5LYAeaV6
15. Function
•Vitamin B9 (Folate) works with vitamin B12 to help form red blood cells.
• It is needed for the production of DNA, which controls tissue growth
and cell function.
• Any woman who is pregnant should be sure to get enough folate.
• Low levels of folate are linked to birth defects such as spina bifida.
• Many foods are now fortified with folate in the form of folic acid.
https://images.app.goo.gl/Dhouua3Yt73ENEr77
•Vitamin B12 (Cobalamin), like the other B vitamins, is important for metabolism.
• It also helps form red blood cells and maintain the central nervous system.
https://images.app.goo.gl/uFZpabLEwwk71eW96
16. Function
•Vitamin C, also called ascorbic acid, is an antioxidant that
promotes healthy teeth and gums.
• It helps the body absorb iron and maintain healthy tissue.
• It is also essential for wound healing.
https://images.app.goo.gl/Qhp5orEGsGCH73gM6 https://images.app.goo.gl/9v8bmPC8cEFVVVD57
https://images.app.goo.gl/YP87bgEzkf8m1bSv9
17. • Vitamins. (n.d.). . https://medlineplus.gov/ency/article/002399.htm
• Satyanarayana, U. (2013). Biochemistry (4th ed.).
• A. (2021, March 22). General Data Protection Regulation(GDPR) Guidelines
BYJU’S. BYJUS. https://byjus.com/biology/difference-between-fat-soluble-and-
water-soluble-vitamins/
References