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TERATOGENS
MATERNAL DISEASES.
Group 2
 Maternal diseases refers to infections that spread from the mother
to the unborn baby across the placental barrier.
 Diseases to be covered :
 HIV
 Rubella
 Diabetes
 Syphilis.
HIV(human immunodeficiency virus)
 The virus can lead to AIDS which can be transmitted from the mother
through the baby exposure to infected blood during delivery or breast
feeding.
 AIDS usually progresses rapidly in infants and at around 6 months the
baby might experience weight loss, repeated respiratory illness. The
virus also causes brain damage as indicated by seizures, brain weight
loss and also delayed mental and motor development.
 Most prenatal AIDS babies dies at around 1 year.
 Mothers are usually encouraged to be tested throughout their pregnancy
so that if they have the virus they can go through Antiretroviral drug
therapy which reduces prenatal AIDS transmission by as much as 95%
Rubella
 The virus attacked around mid 1960s
 It is also known as 3 day measles and it is a condition with symptoms
of rush, swollen lymph glands and lower fever.
 Children who are infected at around embryonic stage of pregnancy
usually they exhibit a syndrome of congenital heart disease.
 Infected children also show signs of blindness as well as heart, urinary,
genital and intestinal defects. Infections during the fetal period results
in low birth weight and bone defects. The virus also has lifelong defects
of severe mental illness and diabetes.
 Vaccination has greatly reduced the infections to the baby.
Diabetes.
 Diabetic mothers usually face risks having still birth or the baby dies after
birth.
 Raised blood sugar during the first trimester usually results in birth defects and
miscarriages.
 Traditional diabetes leads to macrosomia and the infected baby likely face
shoulder dystocia during birth which results in damages on the shoulders
 Due to the extra insulin that will be produced by the baby’s pancreas the new
born may face low blood glucose and risks of breathing problems.
 Excess insulin causes risks of obesity and when they become adults they may
face type 2 diabetes.
 Diabetic mothers need serious care so as to reduce infection on the baby.
Syphilis
 It usually affect the unborn baby after 21 week of gestation since before
these week the syphilis spirochete cannot penetrate through the
placental membrane. 25% of infected foetuses are born dead and those
who survive may be deaf, mentally retarded or deformed.
 Syphilis can be treated effectively with penicillin regimen and should
be initiated 30 days or more before delivery.
 Pregnant mother should continuously go for blood test with their sexual
partners so as to make sure that the baby is protected from syphilis
Group members
 1.Mujati Nyasha M R215453N HCDP
 2.Kambare Valerie T R216431L HDP
 3.Mahlatini Lisa R215450W HCDP
 4. Chidenyika Ruth R215443X HCDP
 5.Nyoni Dion N R215454V HCDP
 6.Mundopa Winnie R216447D HDP
 7.Mbonjani Amanda T R216468E HDP
 8.Ruvimbo Manzvanzvike R21 6463F
 9.Thembelihle Charity Mnkandla R196941Z HCDP
 10.Mercy Matinetsa Zingwe R215457M HCDP
 11.Tambanewenyu Tadiwa R216472P HDP
 12. Zinessah Milliscent R216461W HDP
 13.Matara Rutendo 216429C HDP
 14.Mahambe Tinotenda R216474Q HDP
 15. Nyoni Rumbidzai j R215426K HCDP
 16.Chigamba Patricia R215436N HCDP
 17. Thomas Donald T R216460G HDP
 18. Nyamadzawo Daphine R215423R HCDP
 19 .Zinyowera Lynn Nelly R215433C HCDP

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GROUP 2 MATERNAL DISEASES (1).pptx

  • 2. Group 2  Maternal diseases refers to infections that spread from the mother to the unborn baby across the placental barrier.  Diseases to be covered :  HIV  Rubella  Diabetes  Syphilis.
  • 3. HIV(human immunodeficiency virus)  The virus can lead to AIDS which can be transmitted from the mother through the baby exposure to infected blood during delivery or breast feeding.  AIDS usually progresses rapidly in infants and at around 6 months the baby might experience weight loss, repeated respiratory illness. The virus also causes brain damage as indicated by seizures, brain weight loss and also delayed mental and motor development.  Most prenatal AIDS babies dies at around 1 year.  Mothers are usually encouraged to be tested throughout their pregnancy so that if they have the virus they can go through Antiretroviral drug therapy which reduces prenatal AIDS transmission by as much as 95%
  • 4. Rubella  The virus attacked around mid 1960s  It is also known as 3 day measles and it is a condition with symptoms of rush, swollen lymph glands and lower fever.  Children who are infected at around embryonic stage of pregnancy usually they exhibit a syndrome of congenital heart disease.  Infected children also show signs of blindness as well as heart, urinary, genital and intestinal defects. Infections during the fetal period results in low birth weight and bone defects. The virus also has lifelong defects of severe mental illness and diabetes.  Vaccination has greatly reduced the infections to the baby.
  • 5. Diabetes.  Diabetic mothers usually face risks having still birth or the baby dies after birth.  Raised blood sugar during the first trimester usually results in birth defects and miscarriages.  Traditional diabetes leads to macrosomia and the infected baby likely face shoulder dystocia during birth which results in damages on the shoulders  Due to the extra insulin that will be produced by the baby’s pancreas the new born may face low blood glucose and risks of breathing problems.  Excess insulin causes risks of obesity and when they become adults they may face type 2 diabetes.  Diabetic mothers need serious care so as to reduce infection on the baby.
  • 6. Syphilis  It usually affect the unborn baby after 21 week of gestation since before these week the syphilis spirochete cannot penetrate through the placental membrane. 25% of infected foetuses are born dead and those who survive may be deaf, mentally retarded or deformed.  Syphilis can be treated effectively with penicillin regimen and should be initiated 30 days or more before delivery.  Pregnant mother should continuously go for blood test with their sexual partners so as to make sure that the baby is protected from syphilis
  • 7. Group members  1.Mujati Nyasha M R215453N HCDP  2.Kambare Valerie T R216431L HDP  3.Mahlatini Lisa R215450W HCDP  4. Chidenyika Ruth R215443X HCDP  5.Nyoni Dion N R215454V HCDP  6.Mundopa Winnie R216447D HDP  7.Mbonjani Amanda T R216468E HDP  8.Ruvimbo Manzvanzvike R21 6463F  9.Thembelihle Charity Mnkandla R196941Z HCDP  10.Mercy Matinetsa Zingwe R215457M HCDP  11.Tambanewenyu Tadiwa R216472P HDP  12. Zinessah Milliscent R216461W HDP  13.Matara Rutendo 216429C HDP
  • 8.  14.Mahambe Tinotenda R216474Q HDP  15. Nyoni Rumbidzai j R215426K HCDP  16.Chigamba Patricia R215436N HCDP  17. Thomas Donald T R216460G HDP  18. Nyamadzawo Daphine R215423R HCDP  19 .Zinyowera Lynn Nelly R215433C HCDP