Kaletra (HIV) - Forecast and Market Analysis to 2022 Summary GlobalData has released its new PharmaPoint Drug Evaluation report, 'Kaletra (HIV) - Forecast and Market Analysis to 2022'. Human Immunodeficiency Virus (HIV), the causative agent of AIDS, has claimed millions of lives since its emergence. However, the advent of antiretroviral therapy (ART) has transformed the face of HIV/AIDS from a deadly disease to a manageable chronic condition for most infected individuals. Antiretroviral treatment not only reduces the viral load and reconstitutes immune function, but also decreases infection incidence rates by limiting viral transmission. The treatment algorithm in HIV has characteristically involved multiple drug regimens designed to tackle the virus on different levels. In the recent past, simplified dosing regimens through the emergence of single tablet regimens (STRs) or fixed dose combination (FDC) therapies have become increasingly popular amongst physicians and patients alike by increasing clinical efficacy thresholds and enabling patient compliance.Kaletra is a fixed-dose combination of two PIs, lopinavir and Norvir (ritonavir). The drug is indicated in combination with other antiretroviral agents for the treatment of HIV infection in the US and EU, Japan, Brazil and China. Scope - Overview of HIV, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.- Detailed information on Kaletra including product description, safety and efficacy profiles as well as a SWOT analysis.- Sales forecast for Kaletra for the top nine countries from 2012 to 2022.- Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan, Brazil and China Reasons to buy - Understand and capitalize by identifying products that are most likely to ensure a robust return- Stay ahead of the competition by understanding the changing competitive landscape for HIV- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential- Make more informed business decisions from insightful and in-depth analysis of Kaletra performance- Obtain sales forecast for Kaletra from 2012-2022 in top nine countries (the US, France, Germany, Italy, Spain, the UK, Japan, Brazil and China)

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Kaletra (HIV) - Forecast and Market Analysis to 2022
Published on January 2013
Report Summary
Kaletra (HIV) - Forecast and Market Analysis to 2022
Summary
GlobalData has released its new PharmaPoint Drug Evaluation report, 'Kaletra (HIV) - Forecast and Market Analysis to 2022'. Human
Immunodeficiency Virus (HIV), the causative agent of AIDS, has claimed millions of lives since its emergence. However, the advent of
antiretroviral therapy (ART) has transformed the face of HIV/AIDS from a deadly disease to a manageable chronic condition for most
infected individuals. Antiretroviral treatment not only reduces the viral load and reconstitutes immune function, but also decreases
infection incidence rates by limiting viral transmission. The treatment algorithm in HIV has characteristically involved multiple drug
regimens designed to tackle the virus on different levels. In the recent past, simplified dosing regimens through the emergence of
single tablet regimens (STRs) or fixed dose combination (FDC) therapies have become increasingly popular amongst physicians and
patients alike by increasing clinical efficacy thresholds and enabling patient compliance.
Kaletra is a fixed-dose combination of two PIs, lopinavir and Norvir (ritonavir). The drug is indicated in combination with other
antiretroviral agents for the treatment of HIV infection in the US and EU, Japan, Brazil and China.
Scope
- Overview of HIV, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview
on the competitive landscape.
- Detailed information on Kaletra including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for Kaletra for the top nine countries from 2012 to 2022.
- Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan, Brazil and China
Reasons to buy
- Understand and capitalize by identifying products that are most likely to ensure a robust return
- Stay ahead of the competition by understanding the changing competitive landscape for HIV
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
- Make more informed business decisions from insightful and in-depth analysis of Kaletra performance
- Obtain sales forecast for Kaletra from 2012-2022 in top nine countries (the US, France, Germany, Italy, Spain, the UK, Japan, Brazil
and China)
Table of Content
1 Table of Contents
1 Table of Contents 4
1.1 List of Tables 6
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1.2 List of Figures 6
2 Introduction 7
2.1 Catalyst 7
2.2 Related Reports 7
3 Disease Overview 9
3.1 Etiology and Pathophysiology 9
3.1.1 Etiology 9
3.1.2 Pathophysiology 12
3.1.3 Prognosis 12
3.1.4 Quality of Life 13
3.2 Symptoms 13
3.2.1 Primary or Acute Infection 13
3.2.2 Chronic Infection 13
3.2.3 Advanced Infection/AIDS 14
4 Disease Management 15
4.1 Treatment Overview 15
5 Competitive Assessment 19
5.1 Overview 19
5.2 Strategic Competitor Assessment 19
6 Kaletra (lopinavir/ritonavir) 22
6.1 Overview 22
6.2 Efficacy 24
6.3 Safety 24
6.4 SWOT Analysis 24
6.5 Forecast 26
7 Appendix 27
7.1 Bibliography 27
7.2 Abbreviations 29
7.3 Methodology 31
7.4 Forecasting Methodology 31
7.4.1 HIV Prevalence 31
7.4.2 Percent Drug-Treated Patients 31
7.4.3 General Pricing Assumptions 32
7.4.4 Individual Drug Assumptions 33
7.4.5 Generic Erosion 33
7.5 Physicians and Specialists Included in this Study 34
7.5.1 Survery of Prescribing Physicians 35
7.6 About the Authors 35
7.6.1 Authors 35
7.6.2 Global Head of Healthcare 36
7.7 About GlobalData 37
7.8 Contact Us 37
7.9 Disclaimer 37
List of Tables
Table 1: Symptoms HIV 14
Table 2: Treatment Guidelines for HIV 16
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Table 3: Most Prescribed Drugs for HIV by Class in the Global Markets, 2012 17
Table 4: Leading Treatments for HIV, 2012 21
Table 5: Product Profile ' Kaletra 23
Table 6: Kaletra SWOT Analysis, 2012 25
Table 7: Global Sales Forecasts ($m) for Kaletra, 2012-2022 26
Table 8: Physicians Surveyed, By Country 35
List of Figures
Figure 1: HIV Lifecycle 10
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