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Alcon Inc.: PharmaVitae Profile
Published on July 2010

                                                                                                             Report Summary

Introduction


This analysis examines the historical and forecast performance for Alcon in the prescription pharmaceutical sector. The profile
encompasses global company strategy, portfolio and pipeline analysis and assessment of financial performance, with 1-6 year sales
forecasts for key drugs. An interactive forecasting and analysis tool provides continually updated quantitative and qualitative
information.


Scope




Highlights




Reasons to Purchase


Benchmark Alcon's performance against key rivals in the prescription pharmaceutical sectorSee how new launches have driven the
company's impressive growth throughout the historic periodAssess how Alcon's tight therapeutic performance will affect its
performance out to 2014 and the returns on Novartis' investment




                                                                                                             Table of Content

ABOUT DATAMONITOR HEALTHCARE 2
About the PharmaVitae team 2
Chapter 1 About this profile 3
PharmaVitae Explorer database 3
Chapter structure 3
Executive summary 3
Quarterly news update 3
Company introduction 3
Company sales 4
Company financials 4
Key products and competitors 4
Data sourcing 4
Sales data 4
Analyst consensus 4
Chapter 2 Executive summary 5



Alcon Inc.: PharmaVitae Profile                                                                                                   Page 1/7
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Key findings 5
Prescription pharmaceutical sales and growth rate performance, 2002-14 6
Financial performance, 2002-14 7
Alcon: PharmaVitae forecasts at a glance 8
Strategic insight 9
Global leader in ophthalmology 9
Broad coverage of attractive markets 9
Margin expansion to maximize operating profit 9
Ophthalmology focus may restrict opportunity 11
Challenges faced in ophthalmic markets 11
Limited availability of externally discovered products 11
Potential consolidation with Novartis would allow further synergies 13
Two-step agreement to sell Nestlé's holding 13
Complementary fit with Novartis's ophthalmics business 14
Majority stake will not alone allow integration of the two businesses 15
SWOT analysis 16
Table of Contents 17
Table of figures 19
Chapter 3 Quarterly news update 20
Key findings 20
Product developments 21
Deals and alliances 22
Product deals 22
Technology deals 22
M&A activity 23
Company announcements 23
Future product milestones 24
Chapter 4 Company introduction 25
Key findings 25
Background 26
Key corporate developments 26
M&A history 27
Current corporate structure 29
Chapter 5 Company sales 30
Key findings 30
Prescription pharmaceutical sales and growth rate analysis, 2002-14 31
Product analysis 33
Product analysis, 2002-08 34
Product analysis, 2008-14 37
Therapy area analysis 41
Geographic analysis 47
Launch/core/expiry analysis 50
Explanation of launch/core/expiry analysis 50
Launch analysis, 2008-14 51
Core analysis, 2008-14 53
Expiry analysis, 2008-14 55
Generics analysis, 2008-14 57
Launch/core/expiry configuration, 2008-14 58
Molecule type analysis 59
Externalization analysis 61


Alcon Inc.: PharmaVitae Profile                                                                              Page 2/7
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Chapter 6 Company financials 63
Key findings 63
Reconciliation between PharmaVitae-formatted prescription pharma sales and company-reported total sales, 2002-08 64
Operating costs and profit analysis 66
Operating costs and profit analysis, 2002-08 67
Operating cost ratio and profit margin analysis, 2002-08 68
Operating cost ratio and profit margin analysis, 2008-14 69
Operating costs and profit analysis, 2008-14 71
Chapter 7 Key products and competitors 73
Key findings 73
Overview 74
Other 75
Travatan franchise 75
Overview 75
Sales forecast 76
Market uptake against gold standard, Xalatan 76
Increasing competition from indirect generics 77
Travatan Z helps to differentiate Alcon's offering 77
Threat of earlier than forecast direct generics 78
Azopt 79
Overview 79
Sales forecast 80
Competition with the Trusopt franchise in the carbonic anhydrase inhibitor class 80
Generic carbonic anhydrase inhibitors became available from October 2008 80
Azarga strengthens ex-US sales 81
Patanol franchise 82
Overview 82
Sales forecast 83
Maximization of deal with Kyowa Hakko Kirin 83
Generic copies of key competitor from 2009 84
Infectious diseases 85
Vigamox 85
Overview 85
Sales forecast 86
Fourth-generation anti-infective 86
Delays reduce further opportunity for switching 86
Ciprodex 88
Overview 88
Sales forecast 89
Generic copies forecast to launch in the US from 2010 89
MoxiDex Otic will launch too late to allow direct switching 89
Respiratory 90
Patanase 90
Overview 90
Sales forecast 91
Initial market uptake will clarify potential 91
Generic copies of Astelin threaten sales from 2010 91
Chapter 8 Appendix 93
R&D pipeline 93
Therapy area by company reporting line 94


Alcon Inc.: PharmaVitae Profile                                                                                       Page 3/7
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References 98
Abbreviations 98
Exchange rates 100
About Datamonitor 101
About Datamonitor Healthcare 101
Datamonitor consulting 101
Disclaimer 103


List of Tables
Table 1: Alcon - PharmaVitae forecasts at a glance 8
Table 2: Alcon key product developments, Q1-Q3 2009 21
Table 3: Alcon product deals and alliances, Q1-Q3 2009 22
Table 4: Alcon technology deals and alliances, Q1-Q3 2009 22
Table 5: Alcon M&A activity, Q1-Q3 2009 23
Table 6: Alcon company announcements, Q1-Q3 2009 23
Table 7: Alcon future product milestones, 2009-11 24
Table 8: Alcon product portfolio overview ($m), 2002-08 34
Table 9: Alcon product portfolio overview ($m), 2008-14 37
Table 10: Alcon prescription pharmaceutical sales by therapy area ($m), 2008-14 46
Table 11: Alcon prescription pharmaceutical sales by geographic region ($m), 2008-14 49
Table 12: Alcon launch portfolio overview ($m), 2008-14 51
Table 13: Alcon core portfolio overview ($m), 2008-14 53
Table 14: Alcon expiry portfolio overview ($m), 2008-14 55
Table 15: Alcon generics portfolio overview ($m), 2008-14 57
Table 16: Alcon prescription pharmaceutical sales by molecule type ($m), 2008-14 60
Table 17: Alcon prescription pharmaceutical sales by source ($m), 2008-14 62
Table 18: Total Alcon sales by business unit ($m), 2002-08 64
Table 19: Alcon operating revenue/cost analysis ($m), 2002-08 67
Table 20: Alcon operating cost ratio analysis (% of total revenues), 2002-08 68
Table 21: Alcon operating cost ratio analysis (% of total revenues), 2008-14 69
Table 22: Alcon operating revenue/cost analysis ($m), 2008-14 71
Table 23: Key products overview 74
Table 24: Travatan: overview 75
Table 25: Travatan franchise: sales forecast ($m), 2008-14 76
Table 26: DuoTrav: sales forecast ($m), 2008-14 76
Table 27: Azopt: overview 79
Table 28: Azopt: sales forecast ($m), 2008-14 80
Table 29: Patanol: overview 82
Table 30: Patanol franchise: sales forecast ($m), 2008-14 83
Table 31: Vigamox: overview 85
Table 32: Vigamox: sales forecast ($m), 2008-14 86
Table 33: Ciprodex: overview 88
Table 34: Ciprodex: sales forecast ($m), 2008-14 89
Table 35: Patanase: overview 90
Table 36: Patanase: sales forecast ($m), 2008-14 91
Table 37: Alcon's R&D pipeline (Phase I-registration) 93
Table 38: Alcon product portfolio overview ($m), 2002-08 94
Table 39: Alcon product portfolio overview ($m), 2008-14 96
Table 40: Exchange rates, 2009 100




Alcon Inc.: PharmaVitae Profile                                                                             Page 4/7
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List of Figures
Figure 1: The PharmaVitae Explorer 3
Figure 2: Alcon prescription pharmaceutical performance, sales ($m) and growth rate (%), 2002-14 6
Figure 3: Alcon's financial performance ($m), 2002-14 7
Figure 4: Alcon total revenue and operating profit breakdown, 2002-14 10
Figure 5: Alcon share price and timeframe of put/call options on Nestlé's remaining 52% stake, 2002-11 13
Figure 6: Synergies between Alcon and Novartis 14
Figure 7: Alcon SWOT analysis 16
Figure 8: Recent and major M&A/divestment activity, Alcon 27
Figure 9: Current corporate structure 29
Figure 10: Alcon prescription pharmaceutical performance, sales ($m) and growth rate (%), 2002-14 31
Figure 11: Key product sales ($m), 2002-14 33
Figure 12: Alcon key sales growth drivers and resistors ($m), 2002-08 35
Figure 13: Alcon key sales growth drivers and resistors ($m), 2008-14 38
Figure 14: Alcon prescription pharmaceutical sales by therapy area ($m), 2002-14 41
Figure 15: Alcon prescription pharmaceutical sales by product category ($m), 2002-14 42
Figure 16: Alcon prescription pharmaceutical sales by geographic region ($m), 2002-14 47
Figure 17: Alcon launch/core/expiry configuration ($m), 2008-14 58
Figure 18: Alcon prescription pharmaceutical sales by molecule type ($m), 2002-14 59
Figure 19: Alcon prescription pharmaceutical sales by source ($m), 2002-14 61
Figure 20: Alcon operating revenue/cost analysis ($m), 2002-14 66




Alcon Inc.: PharmaVitae Profile                                                                              Page 5/7
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Alcon Inc.: PharmaVitae Profile                                                                                                       Page 6/7
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Alcon Inc.: PharmaVitae Profile                                                                                         Page 7/7

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Alcon Inc.: PharmaVitae Profile

  • 1. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Alcon Inc.: PharmaVitae Profile Published on July 2010 Report Summary Introduction This analysis examines the historical and forecast performance for Alcon in the prescription pharmaceutical sector. The profile encompasses global company strategy, portfolio and pipeline analysis and assessment of financial performance, with 1-6 year sales forecasts for key drugs. An interactive forecasting and analysis tool provides continually updated quantitative and qualitative information. Scope Highlights Reasons to Purchase Benchmark Alcon's performance against key rivals in the prescription pharmaceutical sectorSee how new launches have driven the company's impressive growth throughout the historic periodAssess how Alcon's tight therapeutic performance will affect its performance out to 2014 and the returns on Novartis' investment Table of Content ABOUT DATAMONITOR HEALTHCARE 2 About the PharmaVitae team 2 Chapter 1 About this profile 3 PharmaVitae Explorer database 3 Chapter structure 3 Executive summary 3 Quarterly news update 3 Company introduction 3 Company sales 4 Company financials 4 Key products and competitors 4 Data sourcing 4 Sales data 4 Analyst consensus 4 Chapter 2 Executive summary 5 Alcon Inc.: PharmaVitae Profile Page 1/7
  • 2. Find Industry reports, Company profiles ReportLinker and Market Statistics Key findings 5 Prescription pharmaceutical sales and growth rate performance, 2002-14 6 Financial performance, 2002-14 7 Alcon: PharmaVitae forecasts at a glance 8 Strategic insight 9 Global leader in ophthalmology 9 Broad coverage of attractive markets 9 Margin expansion to maximize operating profit 9 Ophthalmology focus may restrict opportunity 11 Challenges faced in ophthalmic markets 11 Limited availability of externally discovered products 11 Potential consolidation with Novartis would allow further synergies 13 Two-step agreement to sell Nestlé's holding 13 Complementary fit with Novartis's ophthalmics business 14 Majority stake will not alone allow integration of the two businesses 15 SWOT analysis 16 Table of Contents 17 Table of figures 19 Chapter 3 Quarterly news update 20 Key findings 20 Product developments 21 Deals and alliances 22 Product deals 22 Technology deals 22 M&A activity 23 Company announcements 23 Future product milestones 24 Chapter 4 Company introduction 25 Key findings 25 Background 26 Key corporate developments 26 M&A history 27 Current corporate structure 29 Chapter 5 Company sales 30 Key findings 30 Prescription pharmaceutical sales and growth rate analysis, 2002-14 31 Product analysis 33 Product analysis, 2002-08 34 Product analysis, 2008-14 37 Therapy area analysis 41 Geographic analysis 47 Launch/core/expiry analysis 50 Explanation of launch/core/expiry analysis 50 Launch analysis, 2008-14 51 Core analysis, 2008-14 53 Expiry analysis, 2008-14 55 Generics analysis, 2008-14 57 Launch/core/expiry configuration, 2008-14 58 Molecule type analysis 59 Externalization analysis 61 Alcon Inc.: PharmaVitae Profile Page 2/7
  • 3. Find Industry reports, Company profiles ReportLinker and Market Statistics Chapter 6 Company financials 63 Key findings 63 Reconciliation between PharmaVitae-formatted prescription pharma sales and company-reported total sales, 2002-08 64 Operating costs and profit analysis 66 Operating costs and profit analysis, 2002-08 67 Operating cost ratio and profit margin analysis, 2002-08 68 Operating cost ratio and profit margin analysis, 2008-14 69 Operating costs and profit analysis, 2008-14 71 Chapter 7 Key products and competitors 73 Key findings 73 Overview 74 Other 75 Travatan franchise 75 Overview 75 Sales forecast 76 Market uptake against gold standard, Xalatan 76 Increasing competition from indirect generics 77 Travatan Z helps to differentiate Alcon's offering 77 Threat of earlier than forecast direct generics 78 Azopt 79 Overview 79 Sales forecast 80 Competition with the Trusopt franchise in the carbonic anhydrase inhibitor class 80 Generic carbonic anhydrase inhibitors became available from October 2008 80 Azarga strengthens ex-US sales 81 Patanol franchise 82 Overview 82 Sales forecast 83 Maximization of deal with Kyowa Hakko Kirin 83 Generic copies of key competitor from 2009 84 Infectious diseases 85 Vigamox 85 Overview 85 Sales forecast 86 Fourth-generation anti-infective 86 Delays reduce further opportunity for switching 86 Ciprodex 88 Overview 88 Sales forecast 89 Generic copies forecast to launch in the US from 2010 89 MoxiDex Otic will launch too late to allow direct switching 89 Respiratory 90 Patanase 90 Overview 90 Sales forecast 91 Initial market uptake will clarify potential 91 Generic copies of Astelin threaten sales from 2010 91 Chapter 8 Appendix 93 R&D pipeline 93 Therapy area by company reporting line 94 Alcon Inc.: PharmaVitae Profile Page 3/7
  • 4. Find Industry reports, Company profiles ReportLinker and Market Statistics References 98 Abbreviations 98 Exchange rates 100 About Datamonitor 101 About Datamonitor Healthcare 101 Datamonitor consulting 101 Disclaimer 103 List of Tables Table 1: Alcon - PharmaVitae forecasts at a glance 8 Table 2: Alcon key product developments, Q1-Q3 2009 21 Table 3: Alcon product deals and alliances, Q1-Q3 2009 22 Table 4: Alcon technology deals and alliances, Q1-Q3 2009 22 Table 5: Alcon M&A activity, Q1-Q3 2009 23 Table 6: Alcon company announcements, Q1-Q3 2009 23 Table 7: Alcon future product milestones, 2009-11 24 Table 8: Alcon product portfolio overview ($m), 2002-08 34 Table 9: Alcon product portfolio overview ($m), 2008-14 37 Table 10: Alcon prescription pharmaceutical sales by therapy area ($m), 2008-14 46 Table 11: Alcon prescription pharmaceutical sales by geographic region ($m), 2008-14 49 Table 12: Alcon launch portfolio overview ($m), 2008-14 51 Table 13: Alcon core portfolio overview ($m), 2008-14 53 Table 14: Alcon expiry portfolio overview ($m), 2008-14 55 Table 15: Alcon generics portfolio overview ($m), 2008-14 57 Table 16: Alcon prescription pharmaceutical sales by molecule type ($m), 2008-14 60 Table 17: Alcon prescription pharmaceutical sales by source ($m), 2008-14 62 Table 18: Total Alcon sales by business unit ($m), 2002-08 64 Table 19: Alcon operating revenue/cost analysis ($m), 2002-08 67 Table 20: Alcon operating cost ratio analysis (% of total revenues), 2002-08 68 Table 21: Alcon operating cost ratio analysis (% of total revenues), 2008-14 69 Table 22: Alcon operating revenue/cost analysis ($m), 2008-14 71 Table 23: Key products overview 74 Table 24: Travatan: overview 75 Table 25: Travatan franchise: sales forecast ($m), 2008-14 76 Table 26: DuoTrav: sales forecast ($m), 2008-14 76 Table 27: Azopt: overview 79 Table 28: Azopt: sales forecast ($m), 2008-14 80 Table 29: Patanol: overview 82 Table 30: Patanol franchise: sales forecast ($m), 2008-14 83 Table 31: Vigamox: overview 85 Table 32: Vigamox: sales forecast ($m), 2008-14 86 Table 33: Ciprodex: overview 88 Table 34: Ciprodex: sales forecast ($m), 2008-14 89 Table 35: Patanase: overview 90 Table 36: Patanase: sales forecast ($m), 2008-14 91 Table 37: Alcon's R&D pipeline (Phase I-registration) 93 Table 38: Alcon product portfolio overview ($m), 2002-08 94 Table 39: Alcon product portfolio overview ($m), 2008-14 96 Table 40: Exchange rates, 2009 100 Alcon Inc.: PharmaVitae Profile Page 4/7
  • 5. Find Industry reports, Company profiles ReportLinker and Market Statistics List of Figures Figure 1: The PharmaVitae Explorer 3 Figure 2: Alcon prescription pharmaceutical performance, sales ($m) and growth rate (%), 2002-14 6 Figure 3: Alcon's financial performance ($m), 2002-14 7 Figure 4: Alcon total revenue and operating profit breakdown, 2002-14 10 Figure 5: Alcon share price and timeframe of put/call options on Nestlé's remaining 52% stake, 2002-11 13 Figure 6: Synergies between Alcon and Novartis 14 Figure 7: Alcon SWOT analysis 16 Figure 8: Recent and major M&A/divestment activity, Alcon 27 Figure 9: Current corporate structure 29 Figure 10: Alcon prescription pharmaceutical performance, sales ($m) and growth rate (%), 2002-14 31 Figure 11: Key product sales ($m), 2002-14 33 Figure 12: Alcon key sales growth drivers and resistors ($m), 2002-08 35 Figure 13: Alcon key sales growth drivers and resistors ($m), 2008-14 38 Figure 14: Alcon prescription pharmaceutical sales by therapy area ($m), 2002-14 41 Figure 15: Alcon prescription pharmaceutical sales by product category ($m), 2002-14 42 Figure 16: Alcon prescription pharmaceutical sales by geographic region ($m), 2002-14 47 Figure 17: Alcon launch/core/expiry configuration ($m), 2008-14 58 Figure 18: Alcon prescription pharmaceutical sales by molecule type ($m), 2002-14 59 Figure 19: Alcon prescription pharmaceutical sales by source ($m), 2002-14 61 Figure 20: Alcon operating revenue/cost analysis ($m), 2002-14 66 Alcon Inc.: PharmaVitae Profile Page 5/7
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  • 7. Find Industry reports, Company profiles ReportLinker and Market Statistics Payment Information Please indicate the payment method, you would like to use by selecting the appropriate box. Payment by credit card Card Number: ______________________________________________ Expiry Date __________ / _________ CVV Number _____________________ Card Type (ex: Visa, Amex…) _________________________________ Payment by wire transfer Crédit Mutuel RIB : 10278 07314 00020257701 89 BIC : CMCIFR2A IBAN : FR76 1027 8073 1400 0202 5770 189 Payment by check UBIQUICK SAS 16 rue Grenette – 69002 LYON, FRANCE Customer signature:   Please note that by ordering from Reportlinker you are agreeing to our Terms and Conditions at http://www.reportlinker.com/index/terms Please fax this form to: Europe, Middle East and Africa : + 33 4 37 37 15 56 Asia, Oceania and America : + 1 (805) 617 17 93 Alcon Inc.: PharmaVitae Profile Page 7/7