A new important technical advance in radio-guided-surgery is the introduction of a new generation of portable mini gamma camera: Sentinella - your new eyes in intra-operative imaging. A revolutionary & integrated equipment for
real time intra-operative imaging of tumors and superficial OR deep lymph nodes , in open and/or laparoscopic surgery.
Gamma probes cannot give spatial or visual information and often cannot discriminate between sentinel nodes and secondary lymph nodes.
R2Innovations / OncoVision : Sentinella - your new eyes
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2. What is Sentinella : A truly global opportunity A revolutionary & integrated equipment for : Real time intra-operative imaging of tumors and superficial OR deep lymph nodes , in open and/or laparoscopic surgery. A peace of mind warranty for surgeons and referring physicians!
3. Radioguided Surgery: Present Situation Fantastic results, BUT technological limitations: Long learning curve, technical limitation of probes; subjective assessment of sound, limitation of amplitude and depth of detection, low sensibility in nodes near by the tumor / small / deep. Innovation is the vital spark of all human change v.s
4. Radioguided Surgery: Present Situation Limited depth of detection with conventional Gamma probes Problem ~2 or 3 cm
9. Innovation is the vital spark of all human change Radioguided Surgery: wanted Situation NO technological limitations: A complete system for radioguided surgery. Revolutionary integrated cancer detection equipment for ease use in / out the OR. GAMMACAMERA + POINTERS + PROBE + VERIFICATION SOFTWARE Real time vision in OR of tumours and related drainage + lymph nodes, with high sensibility and sensitivity (>75% than probes 1 ): variable FOV and collimator, acquisition time, comparative images IN VIVO / EX VIVO + node verification software . EVIDENCE BASED MEDICINE: Wide range of international publications
ROLL (RadioguideOccult LessionLocalization’ techniek voor niet palpabele leasies. Veel ervaring Clinica Barcelona / Dr Vidal en consorten. Toepassing T1 T2 tumoren en ductaal carcinoma in situ. Sentinel Node (SN) exclussion criteria in breast cancer: - Tumors > 3 cm - Previous chemiotheraphy and radiotheraphy - Previous surgery or lymphadenectomy - Multicentric and multifocal cancer - Pregnants Doel± controle snijranden – elimineren harpoon techniek! 2h after injection images in NMdept: SPECT/CT, LYmfescinitgrafie of Sentinella. 18-24h after injection: surgery with Sentinella.
ROLL (RadioguideOccult LessionLocalization’ techniek voor niet palpabele leasies. Veel ervaring Clinica Barcelona / Dr Vidal en consorten. Toepassing T1 T2 tumoren en ductaal carcinoma in situ. Sentinel Node (SN) exclussion criteria in breast cancer: - Tumors > 3 cm - Previous chemiotheraphy and radiotheraphy - Previous surgery or lymphadenectomy - Multicentric and multifocal cancer - Pregnants Doel± controle snijranden – elimineren harpoon techniek! 2h after injection images in NMdept: SPECT/CT, LYmfescinitgrafie of Sentinella. 18-24h after injection: surgery with Sentinella.
SPECT-CT in combinatie met REAL TIME INTRA OPERATIVE IMAGING: de ideale combinaie voor SN localisatie VOORDELEN: NAUWKEURIGE TUMOR STATUS - high prognostic value & significant TNM! MORE DETAILED ANATOMIC INFORMATION – KRITIEKE ORGANEN! VERBETERED LOCALISATIE EN DIEPTE BEPALING DETECTEREN VAN TWEE RADIONUCLIDES (Jodium / Gd ) VOOR OPTIMALE VERIFICATIE
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