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Sinusitis
Paranasal Sinuses: Anatomy
• There are four pairs of paranasal sinuses.
• The Frontal sinuses, above the eyes in the frontal bone
• The Maxillary sinuses, in the cheekbones, under the eyes.
• The Ethmoid sinuses (Anterior, Middle and Posterior) also called
ethmoid labyrinth are located between the eyes and the nose.
• The Sphenoid sinuses (1 or 2) are located in the body of sphenoid
bone, behind the nose and the eyes.
• They are lined by:
Pseudostratified ciliated
columnar epithelium.
• Anterior group : Maxillary, Anterior Ethmoidal and frontal sinuses.
• Posterior group : Sphenoidal and posterior Ethmoidal sinuses.
• Anterior group they open at the hiatus semilunaris in the middle meatus.
• Posterior group open at the spheno-ethmoidal recess above the superior
turbinate into the superior meatus.
Function of the paranasal sinuses
• Exact function unknown, But:
1. Act as resonance to the voice.
2. Reduce the weight of the skull.
3. Protect the eyes.
4. Humidifying and warming inspired air.
Sinusitis
• Inflammation of the lining of the paranasal sinuses.
• Rhinosinusitis is now the preferred term for this condition.
• According to duration:
1. Acute < 1 month.
2. Subacute 1-3 months.
3. Chronic > 3 month.
• Recurrent sinusitis: Episodes of paranasal sinuses infection, each
lasting less than 30 days and separated by intervals of at least 10
days during which the patient is asymptomatic. (4 per yr).
Pathophysiology:
• The sinuses are lined by respiratory epithelium mucosa. Superficial viscous layer
and underlying serous layers.
• Normal function depends on patent Ostia, Ciliary function and quality of mucosa.
Risk Factors
• Common Cold
• Cystic Fibrosis
• Immotile cilia syndrome
• Nasogastric or Nasotracheal tube
• Immunodeficiency
• Nasal polyps or tumors
• Nasal foreign bodies
• Structural problems
Ostial
obstruction:
Inflammation
URTI
Allergy
Mechanical
Septal deviation
Turbinate
hypertrophy
Polyps
Tumors
Adenoid
hypertrophy
Congenital
abnormalities
Foreign
body
Non-ostial
obstruction
Direct extension
Dental
Trauma
Systemic
Cystic fibrosis
Immotile cilia
syndrome
Immune
Lymphoma,
leukemia
Wegener's
granulomatosis
Immunosuppres
sed patients
ETIOLOGY:
Acute Sinusitis:
• Etiology
• Viral (most common): Rhinovirus, influenza, parainfluenza.
• Bacterial: S.pneumoniae (35%), nontypable H.influenza (35%), Moroxella catarrhali, less common
(S.aureus, anaerobics (dental).
• Must rule out fungal causes in immunocompromised patients. (Aspergillus, Zygomycetes; Mucor
Rhizopus)
• Nosocomial sinusitis caused by gram –ve bacteria (Klebsiella and Pseudomonas), are common in
cases of nasogastric and nasotracheal tubes.
• Viral infection can progress to acute bacterial sinusitis. ( most common risk factor for bacterial
sinusitis).
• Acute sinusitis is a clinical diagnosis.
Diagnosis
• 2 or more major factors
• 1 major & 2 minor factors
• Major factors:
• Facial pain/pressure
• Facial fullness/congestion
• Nasal obstruction
• Purulent nasal discharge
• Hyposmia/anosmia
• Fever
• Minor Factors:
• Headache
• Halitosis
• Fatigue
• Dental pain
• Cough
• Ear pressure/ fullness
 Acute Viral infection lasts for <10 days, if symptoms increase after 5 days or
last longer than 10 days, consider bacterial etiology.
 Anterior rhinoscopy can be done.
 X-ray/ CT scan not recommended unless complications are suspected.
Management
• Mild Symptoms improving within 5 days: symptomatic relief "decongestant" and
watchful management.
• Moderate symptoms that worsen or persist beyond 5 days: intranasal corticosteroid
spray for 14 days if symptomatic relief is noted within 48 hours.
• Severe symptoms that worsen or persist beyond 5 days and refractory to intranasal
corticosteroid: Augmentin (Drug of choice) or clarithromycin therapy ± INCS ± referral
to a specialist or if there is a late complication.
Secondary Antibiotics for Acute Sinusitis
• No response to TX within 3-5 days
• Symptoms present for more than 30 days
• Recurrent sinus infections
• Can give:
• 2nd or 3rd generation cephalosporins (eg, cefuroxime, cefpodoxime, cefdinir)
• macrolides (ie, clarithromycin)
• fluoroquinolones (eg, ciprofloxacin, levofloxacin, moxifloxacin)
• clindamycin.
• Surgical if medical
therapy fails:
• Functional endoscopic
sinus surgery (FESS) :
Opening of the entire
OMC to facilitate
drainage.
• Antral washout:
Irrigation of the
maxillary sinus through
its natural ostium or
through a puncture of
the inferior meatus
(careful of
nasolacrimal duct)
Complications
1.Orbital (Chandler's classification)
• Periorbital cellulitis
• Orbital cellulitis
• Sub periosteal abscess
• Orbital abscess
• Cavernous sinus thrombosis (The most
important sign is pulsating proptosis)
2.Intracranial
• Meningitis
• Abscess
3.Bony
• Sub periosteal frontal bone abscess- Pott's
Puffy tumor
• Osteomyelitis
4.Neurologic
Pott’s puffy tumors
• Characterized by an osteomyelitis of the frontal bone with
frontal breakthrough.
• This results in a swelling on the forehead.
• The infection can also spread inwards, leading to an
intracranial abscess.
• Although it can affect all ages, it is mostly found among
teenagers and adolescents.
Chronic sinusitis
Results from:
• Inadequate treatment of acute sinusitis
• Untreated nasal allergy
• Allergic fungal rhinosinusitis
• Anatomic abnormality e.g. deviated septum
• Underlying dental disease
• Ciliary disorder e.g. cystic fibrosis, Kartagener's
• Chronic inflammatory disorder e.g. Wegener's
Diagnosis
• Sinus aspirate culture is the most accurate but is not practical or
necessary.
• Trans illumination can show fluid but its not reliable.
• CT is the gold standard for sinuses
• MRI
• Conventional Radiology( 4 views):
• Water's view (Occipitomental view): best for Maxillary.
• Caldwel view (Occipitofrontal view): best for Frontal.
• Lateral soft tissue view show adenoid, Sphenoidal sinus and sella turcica.
• Submentovertical view (bucket-handle) show Ethmoidal sinuses.
1.Water's view "with opened mouth" Shows maxillary sinuses, frontal sinuses, anterior
ethmoidal sinuses & via the mouth, the sphenoidal sinuses. Best for maxillary sinuses.
2. Caldwel view (Occipitofrontal view): Shows frontal, maxillary & anterior
ethmoidal sinuses. Best for frontal sinuses.
• 3. Lateral soft tissue view: Shows adenoids, sphenoidal sinuses & sella
turcica. Lateral soft tissue view of the neck and upper thoracic region is
ordered if there is suspicion of foreign body
•
4. Submentovertical view (bucket-handle): Shows ethmoidal
sinuses.
Management
• Antibiotics for 3 to 6 weeks for infectious etiology
• Augmentin (40-50 mg/kg/day).
• Amoxicillin is the best in children (80-90 mg/kg/day).
• Macrolides, Fluroquinolone, clindamycin, flagyl.
• Topical nasal steroid
• Nasal irrigation
• Decongestants
• Surgery, if medical therapy fails or fungal infection
• Remove all disease soft tissue and bone, and obliterate pre-existing sinus
cavity.
• FESS
Thank you

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Sinusitis.pptx

  • 2. Paranasal Sinuses: Anatomy • There are four pairs of paranasal sinuses. • The Frontal sinuses, above the eyes in the frontal bone • The Maxillary sinuses, in the cheekbones, under the eyes. • The Ethmoid sinuses (Anterior, Middle and Posterior) also called ethmoid labyrinth are located between the eyes and the nose. • The Sphenoid sinuses (1 or 2) are located in the body of sphenoid bone, behind the nose and the eyes. • They are lined by: Pseudostratified ciliated columnar epithelium.
  • 3. • Anterior group : Maxillary, Anterior Ethmoidal and frontal sinuses. • Posterior group : Sphenoidal and posterior Ethmoidal sinuses. • Anterior group they open at the hiatus semilunaris in the middle meatus. • Posterior group open at the spheno-ethmoidal recess above the superior turbinate into the superior meatus.
  • 4. Function of the paranasal sinuses • Exact function unknown, But: 1. Act as resonance to the voice. 2. Reduce the weight of the skull. 3. Protect the eyes. 4. Humidifying and warming inspired air.
  • 5.
  • 6. Sinusitis • Inflammation of the lining of the paranasal sinuses. • Rhinosinusitis is now the preferred term for this condition. • According to duration: 1. Acute < 1 month. 2. Subacute 1-3 months. 3. Chronic > 3 month. • Recurrent sinusitis: Episodes of paranasal sinuses infection, each lasting less than 30 days and separated by intervals of at least 10 days during which the patient is asymptomatic. (4 per yr).
  • 7. Pathophysiology: • The sinuses are lined by respiratory epithelium mucosa. Superficial viscous layer and underlying serous layers. • Normal function depends on patent Ostia, Ciliary function and quality of mucosa.
  • 8. Risk Factors • Common Cold • Cystic Fibrosis • Immotile cilia syndrome • Nasogastric or Nasotracheal tube • Immunodeficiency • Nasal polyps or tumors • Nasal foreign bodies • Structural problems
  • 10. Acute Sinusitis: • Etiology • Viral (most common): Rhinovirus, influenza, parainfluenza. • Bacterial: S.pneumoniae (35%), nontypable H.influenza (35%), Moroxella catarrhali, less common (S.aureus, anaerobics (dental). • Must rule out fungal causes in immunocompromised patients. (Aspergillus, Zygomycetes; Mucor Rhizopus) • Nosocomial sinusitis caused by gram –ve bacteria (Klebsiella and Pseudomonas), are common in cases of nasogastric and nasotracheal tubes. • Viral infection can progress to acute bacterial sinusitis. ( most common risk factor for bacterial sinusitis). • Acute sinusitis is a clinical diagnosis.
  • 11. Diagnosis • 2 or more major factors • 1 major & 2 minor factors • Major factors: • Facial pain/pressure • Facial fullness/congestion • Nasal obstruction • Purulent nasal discharge • Hyposmia/anosmia • Fever • Minor Factors: • Headache • Halitosis • Fatigue • Dental pain • Cough • Ear pressure/ fullness  Acute Viral infection lasts for <10 days, if symptoms increase after 5 days or last longer than 10 days, consider bacterial etiology.  Anterior rhinoscopy can be done.  X-ray/ CT scan not recommended unless complications are suspected.
  • 12. Management • Mild Symptoms improving within 5 days: symptomatic relief "decongestant" and watchful management. • Moderate symptoms that worsen or persist beyond 5 days: intranasal corticosteroid spray for 14 days if symptomatic relief is noted within 48 hours. • Severe symptoms that worsen or persist beyond 5 days and refractory to intranasal corticosteroid: Augmentin (Drug of choice) or clarithromycin therapy ± INCS ± referral to a specialist or if there is a late complication.
  • 13. Secondary Antibiotics for Acute Sinusitis • No response to TX within 3-5 days • Symptoms present for more than 30 days • Recurrent sinus infections • Can give: • 2nd or 3rd generation cephalosporins (eg, cefuroxime, cefpodoxime, cefdinir) • macrolides (ie, clarithromycin) • fluoroquinolones (eg, ciprofloxacin, levofloxacin, moxifloxacin) • clindamycin.
  • 14. • Surgical if medical therapy fails: • Functional endoscopic sinus surgery (FESS) : Opening of the entire OMC to facilitate drainage. • Antral washout: Irrigation of the maxillary sinus through its natural ostium or through a puncture of the inferior meatus (careful of nasolacrimal duct)
  • 15. Complications 1.Orbital (Chandler's classification) • Periorbital cellulitis • Orbital cellulitis • Sub periosteal abscess • Orbital abscess • Cavernous sinus thrombosis (The most important sign is pulsating proptosis) 2.Intracranial • Meningitis • Abscess 3.Bony • Sub periosteal frontal bone abscess- Pott's Puffy tumor • Osteomyelitis 4.Neurologic
  • 16. Pott’s puffy tumors • Characterized by an osteomyelitis of the frontal bone with frontal breakthrough. • This results in a swelling on the forehead. • The infection can also spread inwards, leading to an intracranial abscess. • Although it can affect all ages, it is mostly found among teenagers and adolescents.
  • 17. Chronic sinusitis Results from: • Inadequate treatment of acute sinusitis • Untreated nasal allergy • Allergic fungal rhinosinusitis • Anatomic abnormality e.g. deviated septum • Underlying dental disease • Ciliary disorder e.g. cystic fibrosis, Kartagener's • Chronic inflammatory disorder e.g. Wegener's
  • 18. Diagnosis • Sinus aspirate culture is the most accurate but is not practical or necessary. • Trans illumination can show fluid but its not reliable. • CT is the gold standard for sinuses • MRI • Conventional Radiology( 4 views): • Water's view (Occipitomental view): best for Maxillary. • Caldwel view (Occipitofrontal view): best for Frontal. • Lateral soft tissue view show adenoid, Sphenoidal sinus and sella turcica. • Submentovertical view (bucket-handle) show Ethmoidal sinuses.
  • 19. 1.Water's view "with opened mouth" Shows maxillary sinuses, frontal sinuses, anterior ethmoidal sinuses & via the mouth, the sphenoidal sinuses. Best for maxillary sinuses.
  • 20. 2. Caldwel view (Occipitofrontal view): Shows frontal, maxillary & anterior ethmoidal sinuses. Best for frontal sinuses.
  • 21. • 3. Lateral soft tissue view: Shows adenoids, sphenoidal sinuses & sella turcica. Lateral soft tissue view of the neck and upper thoracic region is ordered if there is suspicion of foreign body
  • 22. • 4. Submentovertical view (bucket-handle): Shows ethmoidal sinuses.
  • 23.
  • 24.
  • 25. Management • Antibiotics for 3 to 6 weeks for infectious etiology • Augmentin (40-50 mg/kg/day). • Amoxicillin is the best in children (80-90 mg/kg/day). • Macrolides, Fluroquinolone, clindamycin, flagyl. • Topical nasal steroid • Nasal irrigation • Decongestants • Surgery, if medical therapy fails or fungal infection • Remove all disease soft tissue and bone, and obliterate pre-existing sinus cavity. • FESS

Notas do Editor

  1. They are hollow, air-filled cavities that are lined by a mucous membrane. Maxillary most frequently infected. Roof is floor of the orbit and floor is related to the premolar and molar teeth.