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HEALTH DOSSIER
HEALTH IN THE
BALANCE
From third world to first,
Singapore has garnered
many accolades – the
Republic is ranked by US-
based research institute
Business Environment
Risk Intelligence as
the top investment
destination globally and is
recognised by the World
Economic Forum as the
most competitive in Asia
in terms of efficiency.
Rising standards of living, the
availability of good housing, safe
water supply and sanitation,
and access to high-quality
medical service have helped
to significantly boost the health
of Singapore residents. We are
eating better, earning more and
living well. Today, Singapore’s
life expectancy is at an all-time
high of 82 years, up from 72
years in 1980.
But much like other
developed East Asian urbanised
Affluence brings better nutrition, greater awareness about
health and better medical therapies. But it also brings
lifestyles which are not all good for us. We speak with eight
leading medical specialists from various disciplines, who
share what’s happening and what we can do about it.
societies like Japan, Taiwan and
Hong Kong, strong economic
growth and increasing affluence
have brought about a set of “first-
world” issues. In addition, our
declining birth rate – due to later
marriages and married couples
choosing to delay parenthood
– coupled with a rapidly ageing
population have created a
unique class of health conditions
that need to be tackled.
In fact, the available data tells
a sobering tale of the state of
Singaporeans’ health. According
to the Health Promotion Board,
one in four Singaporeans in
their 40s has at least one or
more of these chronic diseases:
diabetes, hypertension and high
blood cholesterol.
Even though the risk of
contracting chronic illnesses
increases with age, doctors
agree that the rising rate is
attributable to our increasingly
stressful, sedentary and
unhealthy lifestyles. A close
WORDS
QUINTELLA
KOH
40
witness to this shift are
specialists – from fields such
as cardiology, ophthalmology,
rheumatology, ENT, hand
surgery, urology, obstetrics and
gynaecology – who are noticing
clear trends. They are almost
unanimous in concluding that
our diets and lifestyles are
largely to blame.
Contracting chronic
diseases is a serious matter as
many of them, if unchecked
and uncontrolled, lead to other
major illnesses. Cardiologist
Dr Ruth Kam notes that
hypertension can lead to health
complications such as heart
attack, heart failure, stroke,
kidney failure, atrial fibrillation
and dementia. Cardiologist
Dr Eric Hong, who specialises
in multimodal imaging (MMI),
echoes this, reporting that he is
seeing more acute and chronic
heart failures, arrhythmias
(irregular heartbeat) and
structural heart diseases.
Lifestyle
choices
The root of the problem?
Singaporean residents
simply exercise too little and
eat too much. The National
Health Survey (NHS) found
that a staggering 54% of
Singaporean residents aged
18 to 69 did not participate
in any leisure-time physical
activity, compared to
countries like the US (41%)
and France (33%).
As a renowned foodie
heaven, Singapore is seeing
the level of obesity rising.
The NHS found that one
in 10 Singaporeans were
considered obese, more than
twice the number in 1992.
Obesity can not only lead to
diabetes, hypertension and
high cholesterol, it can also
be a prelude to arthritis and
certain classes of cancer.
For example, people who
have hypertension or who
are obese are more prone to
developing bladder stones.
Left untreated, these can
cause discomfort, bacterial
infections and prevent urine
passing from the body,
explains Urologist
Dr Michael Wong.
Singapore has also seen a
slight uptick in the number of
people smoking, which has
led to an increase in throat
and tongue cancers – seen
not only in the elderly but
also the young and females,
says A/Prof Luke Tan,
Ear Nose Throat - Head and
Neck Surgeon.
And while the serious hand
injuries from use of heavy
machines in the 70s and 80s
have become less frequent
as Singapore went high-tech,
today’s hand injuries are
mostly the result of lifestyle
and recreational activities like
sports and computer use,
notes Hand Surgeon Dr Tan
Soo Heong.
Stone treatment
technology has
leapt forward
in the last five
years, as have
techniques
for tackling
male infertility
along with IVF
capabilities.
DR MICHAEL WONG
Associate Editor of the
British Journal of Urology and
Deputy Director of the Asian
School of Urology
54%OF
SINGAPOREANS
AGED
DID NOT PARTICIPATE
IN ANY LEISURE-TIME
PHYSICAL ACTIVITY*
18-69
The bad news is that
urinary stone incidence
has risen in the past 20
years due to changes in
diet and obesity, while
male fertility is a larger
concern due to delayed
marriage and more
second marriages. Female
urinary incontinence
has risen with an ageing
population, as have
prostate enlargement
and cancer. The good
news? Technological
advancements in the form
of better instrumentation,
use of lasers and
robotics and more
targetted medication are,
collectively, tackling these
issues head-on, resulting
in faster recovery, shorter
hospital stays and
improved odds for fertility.
41
A/PROF LUKE TAN
Ear, Nose & Throat – Head
and Neck Surgeon
The general state of
ENT health has improved
significantly over the past
few decades as a result
of education, access to
primary healthcare and
improved medicines.
Thyroid cancer and
thyroid nodular diseases
are on the rise due to
early screening. On the
flipside, the common
issues are predominantly
allergy and sinus-related.
One common trend is
the increased prevalence
of smoking among the
young and in particular,
females.
In the West, there is a
rising trend of sexually
transmitted human
papilloma virus-related
throat cancers, which
would probably reflect
in some way here as
trends in smoking and
sexual activities change
in tandem.
I recently
diagnosed a
20-year-old
motherwith late
Stage 4 tongue
cancer. She
had symptoms
for about six
months.
* Finding from National Health Survey (NHS), a first of its
kindwhichcapturedinformationontheprevalenceofmajor
non-communicable diseases and related risk factors. It
also revealed information on chronic disease screening,
use of primary healthcare services, mental health and
self-rated overall health. It was conducted in 2010; the
next NHS is due in 2016.
HEALTH DOSSIER
Age-related
challenges
Singapore also has to contend
with the rising onset of age-
related conditions such as
infertility, osteoporosis
and myopia.
It is well-known that
Singaporeans are delaying
parenthood – marrying
later, pursuing career goals,
treasuring freedom – but
less well-known is how
the ageing process affects
fertility. Obstetrician and
Gynaecologist Dr Ann Tan
explains, “Fertility potential
peaks in the 20s when desire
(to have children) is low, and
then reverses. Fertility potential
is lower when desire is higher.”
Women may reach
menopause on average
at 51, but the deterioration
starts in the late 20s. After 35,
the female’s fertility drops
dramatically with diminishing
number and quality of eggs.
The spotlight tends to fall
on female infertility, but it is
also male pressing in males.
Urologist Dr Wong says more
people delaying marriage or
entering second marriages
mean that men are older and
sperm quality poorer. Male
infertility issues constitute
about 60% of cases.
Like infertility, the incidence
of osteoporosis is
likely to increase
dramatically as
the city-state’s
median age
pushes towards
47 come 2030
(from 39 in 2011).
Characterised by
decreasing bone
mass and density,
osteoporosis is
a progressive
condition that
results in weak,
brittle bones. It is
most common in
post-menopausal
women following the decrease
in estrogen, a female sex
hormone that protects bones
in women.
Rheumatologist A/Prof
Leong Keng Hong points out
that osteoporosis creeps into
a person’s life undetected as
there are often no symptoms
until fractures occur. “If not
treated, it can result in fractures,
particularly of the wrist, spine
or hip. These occur after little or
no trauma, such as falling down
while walking, and often result in
life-changing disability, ”
he explains.
Then there are the
eyes. Myopia, according to
Ophthalmologist Dr Leo Seo
Wei, has reached “epidemic
proportions” with 90% of adult
Singaporeans facing it. “The
earlier the onset of myopia,
the higher the degree of it.
The higher the degree, the
higher the risk of developing
complications leading to
reduced vision and blindness.
These risks are for life,”
she says.
Young people,
especially
women, are are
susceptible to
autoimmune
diseases such
as lupus,
psoriasis,
schleroderma
and Sjogren’s
syndrome, with
onset usually
between 20
and 50.
A/PROF
LEONG KENG HONG
Rheumatologist
In 2010, MOH did a study on
disability adjusted life years
or DALYS. This measures
years of life lost not just
due to premature death but
also to living with disability.
Rheumatoid arthritis was
No. 12 and osteoarthritis
was No. 16 on the list.
Arthritis is due to
either wear and tear
or inflammation. Left
untreated, the patient has
disability such as being
unable to walk or use
the hands. Autoimmune
diseases arise when
a trigger causes the
body’s immune system
to attack the body’s
own tissue. There are
treatments to control the
underlying causes, and
surgical replacement
of hips and knees, but
there are no specific
preventive measures we
can take to reduce the
risk of contracting these
conditions.
80%OF 18-YEAR-OLD
SINGAPOREANS
ARE MYOPIC
28%OF ASIAN CHILDREN
ARE MYOPIC
SINGAPORE
MYOPIA
ALERT!
42
Preventive
measures, early
detection
The good news is that most of
the conditions that affect our
population are also among the
most preventable.
In the case of chronic
diseases such as diabetes,
hypertension and high
blood cholesterol, a few
simple lifestyle tweaks can
significantly decrease the risk
of contracting these diseases.
The Health Promotion Board
recommends that the average
adult Singapore resident gets
150 minutes of physical activity
a week.
Subtle adjustments to
diet are another way to stave
off diseases. For instance,
a moderately active male
should only consume 2,590
calories each day, while
a fairly active female only
needs 2,035 calories. The
tired adages hold true – more
fruits and vegetables, whole
grains instead of processed
carbohydrates, smaller
portions, less sugar and salt.
Explains Dr Leo: “Many eye
diseases are linked to chronic
diseases. Exercise can help
keep them at bay or limit
their impact if they do occur.
Exercise has also been shown
to lessen the risk of age-related
eye diseases such as diabetic
retinopathy, age-related
Singapore has one of the
highest rates of myopia –
short-sightedness –
in the world.
Child myopia is suspected
when they can’t see things
well in the distance. Other
signs include children
going up close to the TV
to watch shows. “Myopia
is not just about wearing
glasses. LASIK or refractive
surgery may get rid of the
need to wear glasses but it
does not decrease the risk
of blinding complications
associated with myopia.
A study of six-year-old
Chinese children shows
that myopia rates are 29%
in Singapore but only 3%
in Sydney. The primary
difference? Children in
Sydney enjoy 14 hours
per week outdoors while
Singapore children get by
with only three.
Risk factors: excessive
reading, writing, computer
use and lack of time
outdoors in sunlight, which
causes the release of
dopamine in the retina and
prevents excessive eye
growth and myopia.
Myopia has
reached
epidemic
proportions in
Singapore, with
90% of adults
facing it.
DR LEO SEO WEI
Ophthalmologist who sub-
specialises in paediatric
ophthalmology
Good cardiac
health results
from habits
which must
be inculcated
from childhood.
Narrowing of the
arteries occurs
over many
years and bad
dietary habits
are difficult
to change
once they are
ingrained.
DR RUTH KAM
Cardiologist
In stable coronary heart
disease, the symptoms
are predictable. They
occur only after a certain
threshold of activity, such
as exercise, after a meal,
after getting angry and so
on. It is also relieved after
the activity stops.
In unstable coronary
heart disease, the
symptoms become
unpredictable. They occur
at rest or with increasing
frequency and intensity
until they become
persistent, unrelieved
by the usual rest or
medication, culminating in
a heart attack when a part
of the heart muscle dies
because its blood supply
is cut off.
macular degeneration
and glaucoma.”
Consistency is key to
maintaining an active lifestyle,
and sudden intense spurts
of physical activity should
be avoided. “What has been
popular in recent years are
short-distance weekend
triathlons which attract middle-
aged working adults who tend
to be ‘weekend warriors’,” Dr
Hong notes. These amateur
athletes can be prone to
sudden cardiac death – a
condition where seemingly fit
individuals suddenly collapse
and die. “In older athletes
above 35, the main cause
of sudden cardiac death is
coronary artery disease.”
In addition to exercising
moderately and regularly,
Dr Hong advises individuals,
especially those who are keen
on endurance sports, to have a
proper heart screening to avoid
sudden cardiac death. “Be
mindful of your heart,” he says.
“The consequences of sudden
cardiac death go beyond
yourself; they affect your loved
ones. Sudden cardiac arrest is
not rare, but surviving it is.”
A multifaceted approach
to healthy living not only
comprises exercise and a
healthy diet. Early detection
of diseases and timely
treatment can reduce the
chances of complications.
43
HEALTH DOSSIER
Early screening
& detection
HEART: Frequent chest
pain points to a likelihood
of coronary heart disease,
says Dr Kam. “Less common
symptoms include abdominal
pain, palpitations, giddiness,
shoulder pain and jaw pain.
These seem to be more
frequent in women who
also get it later, usually after
menopause,” she adds.
Recent advancements in
cardiac imaging technology
have made it possible to
diagnose more, earlier. “A
decade ago, it was common
to report as normal a scan
with findings suggestive of
‘low likelihood for adverse
cardiac events’. Today, we
know that many patients with
normal ECG could still have
extensive coronary artery
disease even though blood
flow through the arteries has
not been compromised yet,”
explains Cardiologist Dr Hong.
“Applying high-sensitivity CZT
crystal cameras over gamma
camera technology for heart
scans reduces scanning time
by 75%. And the 320-slice
cardiac computed tomography
reduces radiation in a heart
scan by 90%.”
Says Dr Kam: “Stents have
drugs in them that lower the
risk of restenosis – narrowing
at the same place – and some
components are biodegradable
and dissolve over time. The
metal scaffolding remains, and
becomes covered in cells so
that it is inside the vessel wall.”
EYES: Adults at 40 should get a
baseline eye disease screening
which can detect abnormalities
of the visual system and
evidence of systemic diseases
such as hypertension and
diabetes. Says Dr Leo, “Several
common eye diseases –
diabetic retinopathy, age-
related macular degeneration
In older
athletes who
are above 35
years old, the
main cause of
sudden cardiac
death is
coronary artery
disease.
DR ERIC HONG
Cardiologist
HEART
URINARY
TRACT
EYES
In older athletes who are
above 35, the main cause of
sudden cardiac death (SCD)
is coronary artery disease
(CAD). Greater attention
must be paid to individuals
with a history of it, including
those who have had heart
attacks, stents, coronary
bypasses or a known history
of reduced heart function
with chronic diseases
such as diabetes or kidney
disease. These conditions
account for 75 to 80% of
SCD in this age group. It is
very important to assess
one’s fitness to exercise.
In the past few years, there
have been tremendous
advancements in non-
invasive cardiac imaging
for more accurate
assessment of CAD. We live
in exciting times, with rapid
advances in imaging and
interventional cardiology,
which lead to better
patient outcomes.
44
and glaucoma – can impact
people above 40 without
them knowing it. With
intervention, these potentially
blinding diseases often have a
favourable outcome.”
URINARY TRACT: The
occurrence of urinary stones
in elderly people is high at
around 10%. Symptoms are
very obvious: abdominal
pain, abnormally coloured
urine, blood in the urine,
frequent urge to urinate and
inability to urinate. To detect
urinary stones, CT scanning,
ultrasound examination and
urine cultures test are viable
screening options, says Dr
Wong. Tests can indicate
urinary stones, their location
and whether they are causing
damage to the urinary tract.
THROAT: Conditions like
throat cancer can be difficult
to diagnose because the
symptoms can be vague.
They include change in voice,
swallowing difficulties, throat
soreness, persistent cough,
swollen lymph nodes in the
neck, ear pain and wheezing.
Targeted screening methods
such as a laryngoscopy (where
a long flexible tube with a
mirror and a light is inserted
down the throat) are required.
If abnormalities are found,
a tissue sample is tested
for cancer. “The focus is on
screening and early detection
as the treatment outcomes are
dependant to a large extent
on the stage at presentation,”
explains A/Prof Tan.
REPRODUCTIVE SYSTEM: Those
who have been trying for
a baby for a long time can
feel isolated and frustrated.
As treatment options are
wide-ranging – with timed
sexual intercourse, ovulation
induction, in vitro fertilisation
(IVF) and surgery – a specialist
is required so that the problem
can be identified and correct
treatment recommended.
Many delay this.
Says Dr Ann Tan: “I would
like to see men and woman
be more mindful of their
fertility potential and to have
the ability to safeguard their
healthy gametes to be used
when their situation allows
them to actualise their
desire to be parents. Then
we will definitely have less
fertility issues.”
Dr Michael Wong points out
that people worry needlessly
about success rates of
treatment options. “Techniques
for male fertility have improved
along with IVF capabilities.”
BONES: Conditions like
osteoporosis often go
undetected until an episode
occurs. Occasional symptoms
are backache, loss of weight
and a stooped posture.
“Many people think that
boosting one’s calcium intake
will help prevent osteoporosis
but calcium, vitamin D and
exercise can enhance bone
health but cannot arrest the
disease once it is there,” says
A/Prof Leong.
Regular health screening
is still recommended; early
detection improves the
chances of treatment, reduces
risk of premature death and
improves quality of life.
HANDS: Patients often ignore
symptoms until it is very late.
“Delayed treatment can lead
to severe consequences. Cat
bite injuries, if not cleaned,
dressed and accompanied by
antibiotics, can lead to severe
spreading infection affecting
bones, joints and soft tissue.
Numbness and weakness
can be due to carpal tunnel
syndrome which, with neglect,
leads to unremitting pain, loss
of finger sensation and loss of
control of thumb movements,“
explains Dr S H Tan.
REPRODUCTIVE
SYSTEM
BONES
THROAT
45
HEALTH DOSSIER
New frontiers
The boundaries of medicine
have advanced dramatically
in the last few years, making
it possible for more people to
receive treatment without fear
of complications.
Multimodal Imaging (MMI)
In the past, when considering
a condition like coronary
artery disease, the option
was ultrasound of the heart
followed by an invasive
procedure such as a
coronary angiogram.
With MMI, a technology
that has matured rapidly over
the last decade, specialists are
able to assess the severity of
blockages in the arteries non-
invasively. Imaging techniques,
when combined with
anatomical and physiological
data, can produce detailed
feedback that can differentiate
a 71% blockage from a
69% blockage.
“In some cases, the patient
might be wheelchair bound
or his functional status not
very good. So the question
is: do you really want to
do the conventional steps
– angiogram, diagnosis of
multi-vessel disease and heart
bypass surgery – when the
patient cannot take that route?
MMI allows us to individualise
medicine,” notes Dr Hong.
Minimally invasive surgery
MIS is now routine. Take urinary
stones, for instance. “No matter
how big or hard the stones,
we now have the tools to not
only remove them safely but to
even prevent them reccurring.
With increasing incidence in
urinary stones arising from age-
related changes, increased uric
acid levels related to obesity
and a dropping urine PH,
technology and techniques
have improved and offer MIS to
remove them,” says Dr Wong.
Today’s hand
injuries result
from lifestyle
and recreational
activities, strain
from repetitive
tasks, and
degenerative
hand conditions
related to
ageing.
DR TAN SOO HEONG
Hand Surgeon
Chronic disease is looming
large in Singapore. Not only
are more people suffering
from ailments linked to
diabetes and high cholesterol,
they are also getting younger.
Figures from the Ministry
of Health show that two in five
Singaporeans aged 20 years
and above are suffering from
at least one chronic condition,
the most common being
high blood pressure, high
cholesterol and diabetes. These
three illnesses increase the risk
of heart problems and strokes.
CHRONIC
DISEASES &
THE YOUNG2
5SINGAPOREANS
AGED 20 YEARS
AND ABOVE
ARE SUFFERING
FROM AT LEAST
ONE CHRONIC
CONDITION
MINISTRY
OF HEALTH
Hand lacerations with
cut tendons and nerves
during culinary classes,
tendon and pulley injuries
during rock-climbing
or rugby games, torn
ligaments during gym or
yoga classes and hand,
wrist and finger fractures
during cycling, mountain
biking skateboarding or
running are common.
Repetititve strain is also
more common, attributed
to sedentary lifestyles
and our keyboard and
gadget use. With ageing
come osteoarthritis of the
thumb and finger joints,
tendon inflammation
and progressive sensory
loss and muscle wasting.
Neuropathic pain and loss
of function are also to be
expected. These occur so
slowly and so commonly
that people attribute
them to “normal ageing”
and don’t get them
treated early.
46
IN
3D printing
Robotics and 3D printing have
revolutionised many areas
of medicine including hand
therapy and limb retraining
and replacement. “Robotics-
assisted devices can help
in rehabilitation to monitor
and assist in hand therapy
and upper limb retraining.
They can be programmed to
perform specific functions for
the patient’s rehabilitation and
to train patients in daily life
activities,” notes Dr S H Tan.
3D printing technology
works like MMI. In 3D printing,
the patient’s body part is
scanned and the data used to
obtain the normal dimensions.
Implants are then crafted to fit
the patient’s specific profile. “In
the old days, implants came
in standard sizes and lengths,
which meant that during during
surgery, the body was altered
to fit the implants. 3D printing
allows for personalisation, done
much more quickly and at a
much lower cost,” he explains.
Regulatory changes
There are encouraging
changes on the regulatory
front with, for instance, rising
acceptance of social egg
freezing as a recognised form
of preserving eggs before they
are damaged or depleted. From
2012, the American Society
of Reproductive Medicine
declared that egg freezing
is no longer an experimental
procedure. Improvements in
freezing methods and culture
media have given many labs an
almost 100% freeze and post-
thawing survival rate.
In Singapore, egg freezing
is only available in the context
of those suffering from cancer
and desiring to store their
eggs before undergoing
chemotherapy. Egg freezing
is also an option at the post-
chemotherapy stage if they are
not able to consider pregnancy
The most urgent
issue facing
our population
would be the
dichotomy
between their
fertilitywants
and potential. I
would like to see
both men and
woman be more
mindful of their
fertility potential.
DR ANN TAN
Obstetrician and
Gynaecologist
at that time. But with countries
such as the US, Belgium
and the Netherlands already
permitting social egg freezing,
it is a matter of time before
Singapore must decide on her
stance for egg freezing. “For
childless women in their 40s
and beyond, the option will be
to have IVF performed with
their own eggs. They can also
use donor eggs if the former
procedure is not possible.If
unable to carry the pregnancy,
then there will be cause to
consider surrogacy,” Dr Ann Tan
points out.
Regulatory changes
have also made it easier for
Singaporean residents to effect
treatment for chronic conditions
as outpatients. The Medisave
Use for Chronic Disease
Many chemotherapy
agents whilst having the
ability to battle the cancer,
also have the ability to
impair the fertility of the
patient. Currently, when
treatments have improved
quality of life and life
expectancy, the notion of
being a parent has become
increasingly desired and
possible. It has been shown
that when fertility has been
preserved, the patient’s
prognosis improves. Fertility
preservtion can be in the
form of egg freezing for
single or embryo freezing
for couples. With breast
cancer, there is often a
window of opportunity
between diagnosis and
surgery/treatments. This
can be used to stimulate
the patient and have her
eggs retrieved prior to
any chemotherapy and its
harmful effects.
47
Management Programme,
launched in 2006, now includes
diabetes, hypertension, stroke,
osteoarthritis, osteoporosis and
rheumatoid arthritis.
Affluence alone clearly
does not guarantee one a
healthy life. What is needed
is a conscious combination
of good lifestyle and eating
habits and regular screening
and treatment. It also helps
to keep abreast of medical
advancements and regulatory
changes.
HEALTH DOSSIER
48
SPECIALIST ADVISORS
DR RUTH KAM
Cardiologist
RUTH KAM HEART AND
ARRHYTHMIA CLINIC
290 Orchard Road
#14-10 Paragon Medical
Singapore 238859
Tel: 6333 6866
www.arrhythmia.com.sg
Dr Ruth Kam provides general and
specialised services in cardiac
arrhythmias, while lecturing and
consulting for various hospitals
and medical institutions here and
overseas. She has a keen interest
in cardiology in women
and sportsmen.
DR TAN SOO HEONG
Hand Surgeon
HAND, WRIST & UPPER LIMB
SURGERY
3 Mount Elizabeth
#07-01 Mount Elizabeth
Medical Centre
Singapore 228510
Tel: 6737 0177
www.hand.com.sg
Dr Tan Soo Heong is one of a
small number of hand surgeons
in Singapore and has a special
interest in the possibilities
of robotics-assisted devices
and 3D printing’s potential for
personalising surgery.
DR ANN TAN
Obstetrician & Gynaecologist
WOMEN & FETAL CENTRE
 290 Orchard Road
#20-01 Paragon Medical                                                                                 
Singapore 238859                                                                                            
Tel: 6887 1103                                                                                                        
www.anntan.com.sg
Dr Ann Tan provides services
in prenatal diagnosis & care of
mother and foetus, and has a deep
interest in assisted fertility and
related issues. In her commitment
to raising awareness, she is
a regular contributor to local
publications.
A/PROF LEONG KENG HONG
Rheumatologist
LEONG KENG HONG ARTHRITIS
& MEDICAL CLINIC
6 Napier Road
#04-18 Gleneagles
Medical Centre
Singapore 258499
Tel: 6472 4337
www.leongkenghong.com
A/Prof Leong Keng Hong is a
consultant and lecturer with an
active interest in research. He has
a special interest in autoimmune
diseases such as arthritis and lupus,
and degenerative diseases such as
osteoporosis and osteoarthritis.
DR LEO SEO WEI
Ophthalmologist
DR LEO ADULT & PAEDIATRIC
EYE SPECIALIST PTE LTD
3 Mount Elizabeth
#10-04 Mount Elizabeth
Medical Centre
Singapore 228510
Tel: 6737 8366
www.drleoeyespecialist.com
Dr Leo Seo Wei treats all aspects
of ophthalmology, with a special
interest in strabismus surgery and
paediatric ophthalmology. She is
one of a few eye specialists here
performing bladeless, laser-
assisted cataract operations.
DR ERIC HONG
Cardiologist
EH HEART SPECIALIST PTE LTD
3 Mount Elizabeth
#03-09 Mount Elizabeth
Medical Centre
Singapore 228510
Tel: 6736 1068
www.eheartspecialist.com
Dr Eric Hong is an interventional
and nuclear cardiologist who
specialises in minimally and non-
invasive procedures and methods
to diagnose and treat diseases
of the heart.
DR MICHAEL WONG
Urologist
INTERNATIONAL UROLOGY,
FERTILITY & GYNAECOLOGY
CENTRE
3 Mount Elizabeth
#10-09 Mount Elizabeth
Medical Centre
Singapore 228510
Tel: 68381212
www.drmichaelwong.com
Dr Michael Wong, currently
Associate Editor of British
Journal of Urology International,
is recognised for expertise and
contribution to the field of Urology,
in particular minimally invasive
Endourology.
A/PROF LUKE TAN
Ear, Nose & Throat – Head and
Neck Surgeon
LUKE TAN ENT-HEAD & NECK
CENTER & THYROID SURGERY
CENTRE
3 Mount Elizabeth
#14-17 Mount Elizabeth
Medical Centre
Singapore 228510
Tel: 6474 6116
www.thyroidsurgery.com.sg
A/Prof Luke Tan is credited with
building up the first ENT teams
in some Singapore hospitals and
has a special interest in minimally
invasive thyroid surgery, and head
and neck cancers.

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40-49 Health Dossier V5

  • 1. HEALTH DOSSIER HEALTH IN THE BALANCE From third world to first, Singapore has garnered many accolades – the Republic is ranked by US- based research institute Business Environment Risk Intelligence as the top investment destination globally and is recognised by the World Economic Forum as the most competitive in Asia in terms of efficiency. Rising standards of living, the availability of good housing, safe water supply and sanitation, and access to high-quality medical service have helped to significantly boost the health of Singapore residents. We are eating better, earning more and living well. Today, Singapore’s life expectancy is at an all-time high of 82 years, up from 72 years in 1980. But much like other developed East Asian urbanised Affluence brings better nutrition, greater awareness about health and better medical therapies. But it also brings lifestyles which are not all good for us. We speak with eight leading medical specialists from various disciplines, who share what’s happening and what we can do about it. societies like Japan, Taiwan and Hong Kong, strong economic growth and increasing affluence have brought about a set of “first- world” issues. In addition, our declining birth rate – due to later marriages and married couples choosing to delay parenthood – coupled with a rapidly ageing population have created a unique class of health conditions that need to be tackled. In fact, the available data tells a sobering tale of the state of Singaporeans’ health. According to the Health Promotion Board, one in four Singaporeans in their 40s has at least one or more of these chronic diseases: diabetes, hypertension and high blood cholesterol. Even though the risk of contracting chronic illnesses increases with age, doctors agree that the rising rate is attributable to our increasingly stressful, sedentary and unhealthy lifestyles. A close WORDS QUINTELLA KOH 40
  • 2. witness to this shift are specialists – from fields such as cardiology, ophthalmology, rheumatology, ENT, hand surgery, urology, obstetrics and gynaecology – who are noticing clear trends. They are almost unanimous in concluding that our diets and lifestyles are largely to blame. Contracting chronic diseases is a serious matter as many of them, if unchecked and uncontrolled, lead to other major illnesses. Cardiologist Dr Ruth Kam notes that hypertension can lead to health complications such as heart attack, heart failure, stroke, kidney failure, atrial fibrillation and dementia. Cardiologist Dr Eric Hong, who specialises in multimodal imaging (MMI), echoes this, reporting that he is seeing more acute and chronic heart failures, arrhythmias (irregular heartbeat) and structural heart diseases. Lifestyle choices The root of the problem? Singaporean residents simply exercise too little and eat too much. The National Health Survey (NHS) found that a staggering 54% of Singaporean residents aged 18 to 69 did not participate in any leisure-time physical activity, compared to countries like the US (41%) and France (33%). As a renowned foodie heaven, Singapore is seeing the level of obesity rising. The NHS found that one in 10 Singaporeans were considered obese, more than twice the number in 1992. Obesity can not only lead to diabetes, hypertension and high cholesterol, it can also be a prelude to arthritis and certain classes of cancer. For example, people who have hypertension or who are obese are more prone to developing bladder stones. Left untreated, these can cause discomfort, bacterial infections and prevent urine passing from the body, explains Urologist Dr Michael Wong. Singapore has also seen a slight uptick in the number of people smoking, which has led to an increase in throat and tongue cancers – seen not only in the elderly but also the young and females, says A/Prof Luke Tan, Ear Nose Throat - Head and Neck Surgeon. And while the serious hand injuries from use of heavy machines in the 70s and 80s have become less frequent as Singapore went high-tech, today’s hand injuries are mostly the result of lifestyle and recreational activities like sports and computer use, notes Hand Surgeon Dr Tan Soo Heong. Stone treatment technology has leapt forward in the last five years, as have techniques for tackling male infertility along with IVF capabilities. DR MICHAEL WONG Associate Editor of the British Journal of Urology and Deputy Director of the Asian School of Urology 54%OF SINGAPOREANS AGED DID NOT PARTICIPATE IN ANY LEISURE-TIME PHYSICAL ACTIVITY* 18-69 The bad news is that urinary stone incidence has risen in the past 20 years due to changes in diet and obesity, while male fertility is a larger concern due to delayed marriage and more second marriages. Female urinary incontinence has risen with an ageing population, as have prostate enlargement and cancer. The good news? Technological advancements in the form of better instrumentation, use of lasers and robotics and more targetted medication are, collectively, tackling these issues head-on, resulting in faster recovery, shorter hospital stays and improved odds for fertility. 41 A/PROF LUKE TAN Ear, Nose & Throat – Head and Neck Surgeon The general state of ENT health has improved significantly over the past few decades as a result of education, access to primary healthcare and improved medicines. Thyroid cancer and thyroid nodular diseases are on the rise due to early screening. On the flipside, the common issues are predominantly allergy and sinus-related. One common trend is the increased prevalence of smoking among the young and in particular, females. In the West, there is a rising trend of sexually transmitted human papilloma virus-related throat cancers, which would probably reflect in some way here as trends in smoking and sexual activities change in tandem. I recently diagnosed a 20-year-old motherwith late Stage 4 tongue cancer. She had symptoms for about six months. * Finding from National Health Survey (NHS), a first of its kindwhichcapturedinformationontheprevalenceofmajor non-communicable diseases and related risk factors. It also revealed information on chronic disease screening, use of primary healthcare services, mental health and self-rated overall health. It was conducted in 2010; the next NHS is due in 2016.
  • 3. HEALTH DOSSIER Age-related challenges Singapore also has to contend with the rising onset of age- related conditions such as infertility, osteoporosis and myopia. It is well-known that Singaporeans are delaying parenthood – marrying later, pursuing career goals, treasuring freedom – but less well-known is how the ageing process affects fertility. Obstetrician and Gynaecologist Dr Ann Tan explains, “Fertility potential peaks in the 20s when desire (to have children) is low, and then reverses. Fertility potential is lower when desire is higher.” Women may reach menopause on average at 51, but the deterioration starts in the late 20s. After 35, the female’s fertility drops dramatically with diminishing number and quality of eggs. The spotlight tends to fall on female infertility, but it is also male pressing in males. Urologist Dr Wong says more people delaying marriage or entering second marriages mean that men are older and sperm quality poorer. Male infertility issues constitute about 60% of cases. Like infertility, the incidence of osteoporosis is likely to increase dramatically as the city-state’s median age pushes towards 47 come 2030 (from 39 in 2011). Characterised by decreasing bone mass and density, osteoporosis is a progressive condition that results in weak, brittle bones. It is most common in post-menopausal women following the decrease in estrogen, a female sex hormone that protects bones in women. Rheumatologist A/Prof Leong Keng Hong points out that osteoporosis creeps into a person’s life undetected as there are often no symptoms until fractures occur. “If not treated, it can result in fractures, particularly of the wrist, spine or hip. These occur after little or no trauma, such as falling down while walking, and often result in life-changing disability, ” he explains. Then there are the eyes. Myopia, according to Ophthalmologist Dr Leo Seo Wei, has reached “epidemic proportions” with 90% of adult Singaporeans facing it. “The earlier the onset of myopia, the higher the degree of it. The higher the degree, the higher the risk of developing complications leading to reduced vision and blindness. These risks are for life,” she says. Young people, especially women, are are susceptible to autoimmune diseases such as lupus, psoriasis, schleroderma and Sjogren’s syndrome, with onset usually between 20 and 50. A/PROF LEONG KENG HONG Rheumatologist In 2010, MOH did a study on disability adjusted life years or DALYS. This measures years of life lost not just due to premature death but also to living with disability. Rheumatoid arthritis was No. 12 and osteoarthritis was No. 16 on the list. Arthritis is due to either wear and tear or inflammation. Left untreated, the patient has disability such as being unable to walk or use the hands. Autoimmune diseases arise when a trigger causes the body’s immune system to attack the body’s own tissue. There are treatments to control the underlying causes, and surgical replacement of hips and knees, but there are no specific preventive measures we can take to reduce the risk of contracting these conditions. 80%OF 18-YEAR-OLD SINGAPOREANS ARE MYOPIC 28%OF ASIAN CHILDREN ARE MYOPIC SINGAPORE MYOPIA ALERT! 42
  • 4. Preventive measures, early detection The good news is that most of the conditions that affect our population are also among the most preventable. In the case of chronic diseases such as diabetes, hypertension and high blood cholesterol, a few simple lifestyle tweaks can significantly decrease the risk of contracting these diseases. The Health Promotion Board recommends that the average adult Singapore resident gets 150 minutes of physical activity a week. Subtle adjustments to diet are another way to stave off diseases. For instance, a moderately active male should only consume 2,590 calories each day, while a fairly active female only needs 2,035 calories. The tired adages hold true – more fruits and vegetables, whole grains instead of processed carbohydrates, smaller portions, less sugar and salt. Explains Dr Leo: “Many eye diseases are linked to chronic diseases. Exercise can help keep them at bay or limit their impact if they do occur. Exercise has also been shown to lessen the risk of age-related eye diseases such as diabetic retinopathy, age-related Singapore has one of the highest rates of myopia – short-sightedness – in the world. Child myopia is suspected when they can’t see things well in the distance. Other signs include children going up close to the TV to watch shows. “Myopia is not just about wearing glasses. LASIK or refractive surgery may get rid of the need to wear glasses but it does not decrease the risk of blinding complications associated with myopia. A study of six-year-old Chinese children shows that myopia rates are 29% in Singapore but only 3% in Sydney. The primary difference? Children in Sydney enjoy 14 hours per week outdoors while Singapore children get by with only three. Risk factors: excessive reading, writing, computer use and lack of time outdoors in sunlight, which causes the release of dopamine in the retina and prevents excessive eye growth and myopia. Myopia has reached epidemic proportions in Singapore, with 90% of adults facing it. DR LEO SEO WEI Ophthalmologist who sub- specialises in paediatric ophthalmology Good cardiac health results from habits which must be inculcated from childhood. Narrowing of the arteries occurs over many years and bad dietary habits are difficult to change once they are ingrained. DR RUTH KAM Cardiologist In stable coronary heart disease, the symptoms are predictable. They occur only after a certain threshold of activity, such as exercise, after a meal, after getting angry and so on. It is also relieved after the activity stops. In unstable coronary heart disease, the symptoms become unpredictable. They occur at rest or with increasing frequency and intensity until they become persistent, unrelieved by the usual rest or medication, culminating in a heart attack when a part of the heart muscle dies because its blood supply is cut off. macular degeneration and glaucoma.” Consistency is key to maintaining an active lifestyle, and sudden intense spurts of physical activity should be avoided. “What has been popular in recent years are short-distance weekend triathlons which attract middle- aged working adults who tend to be ‘weekend warriors’,” Dr Hong notes. These amateur athletes can be prone to sudden cardiac death – a condition where seemingly fit individuals suddenly collapse and die. “In older athletes above 35, the main cause of sudden cardiac death is coronary artery disease.” In addition to exercising moderately and regularly, Dr Hong advises individuals, especially those who are keen on endurance sports, to have a proper heart screening to avoid sudden cardiac death. “Be mindful of your heart,” he says. “The consequences of sudden cardiac death go beyond yourself; they affect your loved ones. Sudden cardiac arrest is not rare, but surviving it is.” A multifaceted approach to healthy living not only comprises exercise and a healthy diet. Early detection of diseases and timely treatment can reduce the chances of complications. 43
  • 5. HEALTH DOSSIER Early screening & detection HEART: Frequent chest pain points to a likelihood of coronary heart disease, says Dr Kam. “Less common symptoms include abdominal pain, palpitations, giddiness, shoulder pain and jaw pain. These seem to be more frequent in women who also get it later, usually after menopause,” she adds. Recent advancements in cardiac imaging technology have made it possible to diagnose more, earlier. “A decade ago, it was common to report as normal a scan with findings suggestive of ‘low likelihood for adverse cardiac events’. Today, we know that many patients with normal ECG could still have extensive coronary artery disease even though blood flow through the arteries has not been compromised yet,” explains Cardiologist Dr Hong. “Applying high-sensitivity CZT crystal cameras over gamma camera technology for heart scans reduces scanning time by 75%. And the 320-slice cardiac computed tomography reduces radiation in a heart scan by 90%.” Says Dr Kam: “Stents have drugs in them that lower the risk of restenosis – narrowing at the same place – and some components are biodegradable and dissolve over time. The metal scaffolding remains, and becomes covered in cells so that it is inside the vessel wall.” EYES: Adults at 40 should get a baseline eye disease screening which can detect abnormalities of the visual system and evidence of systemic diseases such as hypertension and diabetes. Says Dr Leo, “Several common eye diseases – diabetic retinopathy, age- related macular degeneration In older athletes who are above 35 years old, the main cause of sudden cardiac death is coronary artery disease. DR ERIC HONG Cardiologist HEART URINARY TRACT EYES In older athletes who are above 35, the main cause of sudden cardiac death (SCD) is coronary artery disease (CAD). Greater attention must be paid to individuals with a history of it, including those who have had heart attacks, stents, coronary bypasses or a known history of reduced heart function with chronic diseases such as diabetes or kidney disease. These conditions account for 75 to 80% of SCD in this age group. It is very important to assess one’s fitness to exercise. In the past few years, there have been tremendous advancements in non- invasive cardiac imaging for more accurate assessment of CAD. We live in exciting times, with rapid advances in imaging and interventional cardiology, which lead to better patient outcomes. 44
  • 6. and glaucoma – can impact people above 40 without them knowing it. With intervention, these potentially blinding diseases often have a favourable outcome.” URINARY TRACT: The occurrence of urinary stones in elderly people is high at around 10%. Symptoms are very obvious: abdominal pain, abnormally coloured urine, blood in the urine, frequent urge to urinate and inability to urinate. To detect urinary stones, CT scanning, ultrasound examination and urine cultures test are viable screening options, says Dr Wong. Tests can indicate urinary stones, their location and whether they are causing damage to the urinary tract. THROAT: Conditions like throat cancer can be difficult to diagnose because the symptoms can be vague. They include change in voice, swallowing difficulties, throat soreness, persistent cough, swollen lymph nodes in the neck, ear pain and wheezing. Targeted screening methods such as a laryngoscopy (where a long flexible tube with a mirror and a light is inserted down the throat) are required. If abnormalities are found, a tissue sample is tested for cancer. “The focus is on screening and early detection as the treatment outcomes are dependant to a large extent on the stage at presentation,” explains A/Prof Tan. REPRODUCTIVE SYSTEM: Those who have been trying for a baby for a long time can feel isolated and frustrated. As treatment options are wide-ranging – with timed sexual intercourse, ovulation induction, in vitro fertilisation (IVF) and surgery – a specialist is required so that the problem can be identified and correct treatment recommended. Many delay this. Says Dr Ann Tan: “I would like to see men and woman be more mindful of their fertility potential and to have the ability to safeguard their healthy gametes to be used when their situation allows them to actualise their desire to be parents. Then we will definitely have less fertility issues.” Dr Michael Wong points out that people worry needlessly about success rates of treatment options. “Techniques for male fertility have improved along with IVF capabilities.” BONES: Conditions like osteoporosis often go undetected until an episode occurs. Occasional symptoms are backache, loss of weight and a stooped posture. “Many people think that boosting one’s calcium intake will help prevent osteoporosis but calcium, vitamin D and exercise can enhance bone health but cannot arrest the disease once it is there,” says A/Prof Leong. Regular health screening is still recommended; early detection improves the chances of treatment, reduces risk of premature death and improves quality of life. HANDS: Patients often ignore symptoms until it is very late. “Delayed treatment can lead to severe consequences. Cat bite injuries, if not cleaned, dressed and accompanied by antibiotics, can lead to severe spreading infection affecting bones, joints and soft tissue. Numbness and weakness can be due to carpal tunnel syndrome which, with neglect, leads to unremitting pain, loss of finger sensation and loss of control of thumb movements,“ explains Dr S H Tan. REPRODUCTIVE SYSTEM BONES THROAT 45
  • 7. HEALTH DOSSIER New frontiers The boundaries of medicine have advanced dramatically in the last few years, making it possible for more people to receive treatment without fear of complications. Multimodal Imaging (MMI) In the past, when considering a condition like coronary artery disease, the option was ultrasound of the heart followed by an invasive procedure such as a coronary angiogram. With MMI, a technology that has matured rapidly over the last decade, specialists are able to assess the severity of blockages in the arteries non- invasively. Imaging techniques, when combined with anatomical and physiological data, can produce detailed feedback that can differentiate a 71% blockage from a 69% blockage. “In some cases, the patient might be wheelchair bound or his functional status not very good. So the question is: do you really want to do the conventional steps – angiogram, diagnosis of multi-vessel disease and heart bypass surgery – when the patient cannot take that route? MMI allows us to individualise medicine,” notes Dr Hong. Minimally invasive surgery MIS is now routine. Take urinary stones, for instance. “No matter how big or hard the stones, we now have the tools to not only remove them safely but to even prevent them reccurring. With increasing incidence in urinary stones arising from age- related changes, increased uric acid levels related to obesity and a dropping urine PH, technology and techniques have improved and offer MIS to remove them,” says Dr Wong. Today’s hand injuries result from lifestyle and recreational activities, strain from repetitive tasks, and degenerative hand conditions related to ageing. DR TAN SOO HEONG Hand Surgeon Chronic disease is looming large in Singapore. Not only are more people suffering from ailments linked to diabetes and high cholesterol, they are also getting younger. Figures from the Ministry of Health show that two in five Singaporeans aged 20 years and above are suffering from at least one chronic condition, the most common being high blood pressure, high cholesterol and diabetes. These three illnesses increase the risk of heart problems and strokes. CHRONIC DISEASES & THE YOUNG2 5SINGAPOREANS AGED 20 YEARS AND ABOVE ARE SUFFERING FROM AT LEAST ONE CHRONIC CONDITION MINISTRY OF HEALTH Hand lacerations with cut tendons and nerves during culinary classes, tendon and pulley injuries during rock-climbing or rugby games, torn ligaments during gym or yoga classes and hand, wrist and finger fractures during cycling, mountain biking skateboarding or running are common. Repetititve strain is also more common, attributed to sedentary lifestyles and our keyboard and gadget use. With ageing come osteoarthritis of the thumb and finger joints, tendon inflammation and progressive sensory loss and muscle wasting. Neuropathic pain and loss of function are also to be expected. These occur so slowly and so commonly that people attribute them to “normal ageing” and don’t get them treated early. 46 IN
  • 8. 3D printing Robotics and 3D printing have revolutionised many areas of medicine including hand therapy and limb retraining and replacement. “Robotics- assisted devices can help in rehabilitation to monitor and assist in hand therapy and upper limb retraining. They can be programmed to perform specific functions for the patient’s rehabilitation and to train patients in daily life activities,” notes Dr S H Tan. 3D printing technology works like MMI. In 3D printing, the patient’s body part is scanned and the data used to obtain the normal dimensions. Implants are then crafted to fit the patient’s specific profile. “In the old days, implants came in standard sizes and lengths, which meant that during during surgery, the body was altered to fit the implants. 3D printing allows for personalisation, done much more quickly and at a much lower cost,” he explains. Regulatory changes There are encouraging changes on the regulatory front with, for instance, rising acceptance of social egg freezing as a recognised form of preserving eggs before they are damaged or depleted. From 2012, the American Society of Reproductive Medicine declared that egg freezing is no longer an experimental procedure. Improvements in freezing methods and culture media have given many labs an almost 100% freeze and post- thawing survival rate. In Singapore, egg freezing is only available in the context of those suffering from cancer and desiring to store their eggs before undergoing chemotherapy. Egg freezing is also an option at the post- chemotherapy stage if they are not able to consider pregnancy The most urgent issue facing our population would be the dichotomy between their fertilitywants and potential. I would like to see both men and woman be more mindful of their fertility potential. DR ANN TAN Obstetrician and Gynaecologist at that time. But with countries such as the US, Belgium and the Netherlands already permitting social egg freezing, it is a matter of time before Singapore must decide on her stance for egg freezing. “For childless women in their 40s and beyond, the option will be to have IVF performed with their own eggs. They can also use donor eggs if the former procedure is not possible.If unable to carry the pregnancy, then there will be cause to consider surrogacy,” Dr Ann Tan points out. Regulatory changes have also made it easier for Singaporean residents to effect treatment for chronic conditions as outpatients. The Medisave Use for Chronic Disease Many chemotherapy agents whilst having the ability to battle the cancer, also have the ability to impair the fertility of the patient. Currently, when treatments have improved quality of life and life expectancy, the notion of being a parent has become increasingly desired and possible. It has been shown that when fertility has been preserved, the patient’s prognosis improves. Fertility preservtion can be in the form of egg freezing for single or embryo freezing for couples. With breast cancer, there is often a window of opportunity between diagnosis and surgery/treatments. This can be used to stimulate the patient and have her eggs retrieved prior to any chemotherapy and its harmful effects. 47 Management Programme, launched in 2006, now includes diabetes, hypertension, stroke, osteoarthritis, osteoporosis and rheumatoid arthritis. Affluence alone clearly does not guarantee one a healthy life. What is needed is a conscious combination of good lifestyle and eating habits and regular screening and treatment. It also helps to keep abreast of medical advancements and regulatory changes.
  • 9. HEALTH DOSSIER 48 SPECIALIST ADVISORS DR RUTH KAM Cardiologist RUTH KAM HEART AND ARRHYTHMIA CLINIC 290 Orchard Road #14-10 Paragon Medical Singapore 238859 Tel: 6333 6866 www.arrhythmia.com.sg Dr Ruth Kam provides general and specialised services in cardiac arrhythmias, while lecturing and consulting for various hospitals and medical institutions here and overseas. She has a keen interest in cardiology in women and sportsmen. DR TAN SOO HEONG Hand Surgeon HAND, WRIST & UPPER LIMB SURGERY 3 Mount Elizabeth #07-01 Mount Elizabeth Medical Centre Singapore 228510 Tel: 6737 0177 www.hand.com.sg Dr Tan Soo Heong is one of a small number of hand surgeons in Singapore and has a special interest in the possibilities of robotics-assisted devices and 3D printing’s potential for personalising surgery. DR ANN TAN Obstetrician & Gynaecologist WOMEN & FETAL CENTRE  290 Orchard Road #20-01 Paragon Medical                                                                                  Singapore 238859                                                                                             Tel: 6887 1103                                                                                                         www.anntan.com.sg Dr Ann Tan provides services in prenatal diagnosis & care of mother and foetus, and has a deep interest in assisted fertility and related issues. In her commitment to raising awareness, she is a regular contributor to local publications. A/PROF LEONG KENG HONG Rheumatologist LEONG KENG HONG ARTHRITIS & MEDICAL CLINIC 6 Napier Road #04-18 Gleneagles Medical Centre Singapore 258499 Tel: 6472 4337 www.leongkenghong.com A/Prof Leong Keng Hong is a consultant and lecturer with an active interest in research. He has a special interest in autoimmune diseases such as arthritis and lupus, and degenerative diseases such as osteoporosis and osteoarthritis. DR LEO SEO WEI Ophthalmologist DR LEO ADULT & PAEDIATRIC EYE SPECIALIST PTE LTD 3 Mount Elizabeth #10-04 Mount Elizabeth Medical Centre Singapore 228510 Tel: 6737 8366 www.drleoeyespecialist.com Dr Leo Seo Wei treats all aspects of ophthalmology, with a special interest in strabismus surgery and paediatric ophthalmology. She is one of a few eye specialists here performing bladeless, laser- assisted cataract operations. DR ERIC HONG Cardiologist EH HEART SPECIALIST PTE LTD 3 Mount Elizabeth #03-09 Mount Elizabeth Medical Centre Singapore 228510 Tel: 6736 1068 www.eheartspecialist.com Dr Eric Hong is an interventional and nuclear cardiologist who specialises in minimally and non- invasive procedures and methods to diagnose and treat diseases of the heart. DR MICHAEL WONG Urologist INTERNATIONAL UROLOGY, FERTILITY & GYNAECOLOGY CENTRE 3 Mount Elizabeth #10-09 Mount Elizabeth Medical Centre Singapore 228510 Tel: 68381212 www.drmichaelwong.com Dr Michael Wong, currently Associate Editor of British Journal of Urology International, is recognised for expertise and contribution to the field of Urology, in particular minimally invasive Endourology. A/PROF LUKE TAN Ear, Nose & Throat – Head and Neck Surgeon LUKE TAN ENT-HEAD & NECK CENTER & THYROID SURGERY CENTRE 3 Mount Elizabeth #14-17 Mount Elizabeth Medical Centre Singapore 228510 Tel: 6474 6116 www.thyroidsurgery.com.sg A/Prof Luke Tan is credited with building up the first ENT teams in some Singapore hospitals and has a special interest in minimally invasive thyroid surgery, and head and neck cancers.