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Experiences	with	developing	a	commercial	
solution	to	Johne’s	control	in	the	UK
Peter	Orpin*	1,	2	,	Richard	J.	Sibley3
1	Park	Vet	Group,	Whetstone,	Leicestershire,	2	Special	Lecturer,	
Nottingham	University,	Nottingham,	United	Kingdom,	3	
Westridge Veterinary	Group,	Witheridge,	Tiverton
pete.orpin@myhealthyherd.com
Rising	incidence	in	UK	2000-2010
Risk	of	spread	within	and	between	herds	
increased	with	consolidation,	expansion	
and	intensification	of	herds
Increasing	understanding	of	economic	effects		
in	preclinical	phase
Increasing	cause	of	culling	losses	(	direct	and	
indirect)
Pyramid	of	infection	and	shedding
Myhealthyherd	copyright08/08/2016
Clinical	cows	are	
the	distraction!
Economic	losses	
appear	here
Economic	consequences	of	Johne’s	
Direct
Indirect
Consequential
losses
Premature	culling,	
milk	losses,	
treatments
Increased	risk	of	
udder	disease
Retention	of	high	risk	cows	
with	lower	economic	
performance
Increased	risk	of	lower	fertility,	
further	emergency	culling,	udder	
disease	and	lameness
The	economic	effects	of	Johne’s	disease
Death	or	no	value	cull
Milk	production	loss
Slaughter	value	loss
Disease	associations
Premature	cull
Treatment	costs
Emergency	or	forced	cull
Milk	production	loss
Slaughter	value	loss
Disease	associations
Premature	cull
Premature	planned	cull
Milk	production	loss
Disease	associations
Premature	cull
Cull	cost
£3406/	case
Cull	cost
£2408/	case
Cull	cost
£1304/	case
Drivers	for	the	Johne’s	Engagement	Plan
• Further	improve	Health	and	Welfare
• Economic	benefits	to	the	producers	
• Provide	framework	for	processors	and	farmers	wishing	to	
progress	further	with	Johne’s	control	for	trading	purposes
• Demonstrate	to	consumers	that	any	potential	zoonotic	threat	
is	being	handled	responsibly
Johne’s	Action	Group	and	Conferences
• 2010	Dairy	UK	held	an	industry	
conference	on	Johne’s	disease
• Established	Johne’s		Action	Group	
to	help	co-ordinate	Johne’s	
control	in	GB	Dairy	herd
• Key	members- Vets,	processors,	
milk	recording	organisations,	
farmers	unions
08/08/2016 Myhealthyherd	copyright
Long	Term	Objectives	of	the	
Johne’s	Management	Plan
“To	control	and	then	reduce	the	incidence	of	Johne’s	
disease	in	dairy	cattle	with	the	long	term	objective	of	
eliminating	the	disease	if	it	becomes	technically	and	
economically	feasible	to	do	so”.
Johne’s	Engagement	Plan
• Aim	was	to	engage	all dairy	farmers	in	effective	Johne’s	
management	that	suited	their	farm
• Predict	and	Prevent	Johne’s	disease- protect	the	uninfected	
herds	as	well	as	manage	the	infected	herds
• Key	priority- “Remove	barriers	to	engagement	and	motivate	
vets	and	farmers to	take	positive	action”
Orpin.P.G,	Sibley	R.J..	Predict	and	Prevent	vs	Test	and	Treat.(2014)	
Veterinary	Record 174:	403-405	doi:	10.1136/vr.g2749
Sorry	to	hear	
about	the	Johne’s	
diagnosis
Not	a	problem,	
I’ve	culled	her	
already
“Johne’s	control	is	more	than	just	
a	test	and	cull	program”
The	key	objective	:	Breaking	the	Johne’s	Cycle
Cow infects calf through
milk, faeces or in utero
Calf becomes
infected
Heifer enters herd as
apparently healthy
animal and gradually
develops disease
Myhealthyherd	copyright08/08/2016
UK	Johne’s	Engagement	Program
Education
Surveillance
Risk	
Assessment
Strategic	
controls
Myhealthyherd	copyright08/08/2016
Regional	Control	Schemes
• Two	major	funded	regional	JD	
control	schemes	2011-2014	
• Healthy	Livestock	(	South	West)
• North	West	Regional	
Development
• Delivered	using	Myhealthyherd	
as	central	database
Johne’s	Action	Group- Key	successes
• Common	use	of	IDEXX	ELISA	for	all		major	milk	recording	
organisations
• Established	acceptance	of	milk	ELISA	and	use	of	the	targeted	
30	cow	screen	as	a	tool	for	initial	surveillance
• Promoted	engagement	between	commercial	partners/	
processors
Johne’s	Action	Group- Key	successes
• Retained	focus	on	engaging	
farmers rather	than	surveillance
• Avoided	classification	of	herds	
by	status	as	likely	to	disengage	
infected	farmers
• Education	of	vets	and	farmers	
with	common	messages	
• Engage	all	herds	not	just	
infected-protect	the	uninfected
Avoiding	the	“Focus	on	the	urgent”	
Clinical	Cases Test	positive	cows
Risk	Assessments	and	strategic	controls
• Encouraged	a	strategic	
approach and	developed	and	
endorsed	6	Johne’s	control	
strategies	
• Ensured	risk	assessment	and	
management	central	to	
control		
• Farm	specific	solutions	based	
on	aspirations,	resources,	
prevalence	and	risks
04/07/2016 Myhealthyherd	copyright
Farmer	and	Vet	Friendly	approaches
• Open	access	to	Johne’s	Action	
Group	by	participating	
processors
• Effective	communication	
between	stakeholders
• Avoiding	onerous	rules,	
legalities,	testing	burdens
• Facilitate	vet- farmer	
engagement
First	5	years	JD	engagement	program
• 300+	meetings	to	2500+	farmers	
via	major	milk	processors
• Over	2200	farmers	completed	
risk	assessments	using	
Myhealthyherd
• 350+	vets	educated	in	principles	
of	control
• Annual/	Biennial	Johne’s	
conferences	to	engage	industry
National	Johne’s	Management	Plan	2015
• Strengthen	the	engagement	
process
• Development	of	Action	Johne’s	
website
• Recruitment	of	delivery	team	
tasked	to	help	coordinate	
messages	and	activities
• Develop	technical	manual
National	Johne’s	Management	Plan- Phase	1
• Developed	in	2015	with	
specific	targets
• 77%	of	GB	milk	supply	
signed	up	to	the	program
• Collation	of	results	of	
engagement	by	October	
2016
Collaborative	engagement
National	Johne’s	Management	Plan	objectives	
Phase	1		(2010-2015)
Targets:
• Farmers	to	determine	their	risk	
and	status
• Put	in	place	in	consultation	with	
their	vet	one	of	the	six	strategies	
developed	by	the	Action	Group	
on	Johne’s	in	consultation	with	
their	vet
Low	
Prevalence	
Lower	risk
High	
prevalence
Higher	Risk
Biosecurity	Protect	and	Monitor
Improved	Farm	Management
IMF	and	single	Test
Risk	Based	Control	and	Quarterly	milk	
test
Breed	to	Terminal	Sire
Firebreak	Vaccination
Improved	Farm	Management	and	Test	
and	Cull
Myhealthyherd	copyright04/07/2016
NJMP-Phase	2	(2016+)
• British	Cattle	Vet	Association	
developed	webinar	and	online	
assessment to	create	a	group	of	
approved	trained	vets
• Use	this	group	to	motivate,	
engage	and	ensure	robustness	of	
plans
NJMP	Phase2	Objectives	and	Plans
• Consultation	with	industry with	
plan	for	veterinary	sign	off	of	
robust	veterinary	led	control	plan	
by	BCVA	trained	vet
• Credible	vet/	farmer	interaction
creating	a	robust	protection	and	
control	plan
NJMP	Phase	2-Draft	proposals
• Develop	an	agreed	timescale	for	
veterinary	sign	off	of	plans
• Vets	and	farmers	provided	
choices	as	to	what	tools	and	
approaches	they	use
• Robust	management	plans	
applied,	farmer	pays	for	plan,	
processor	encourages	
compliance,	NJMP	provides	
structure
2017
• January	2017
• Vet	review risks,	control	strategy,	
sign	off
2018
• Annual Review
• Review of	risks/	robustness/	
progress
2019
• Annual	Review
• Review	of	risks/	robustness/	
progress
National	Johne’s	Management	Plan	(NJMP)
Engagement	Timeline
NJMP	Phase	2	– 2016- January	2017+	
Robustness	+	Compliance Trained	vets+	sign	off	of	plan
NJMP	Phase	1- 2015-October	2016
Risks	and	Status 6	Control	Strategies
Johne’s Engagement	2010-2014
Education Risk	and	Status
Where	we	want	to	end	up?
• Farmer	and	industry	commercially	driven	solutions
• Drivers for	continued	engagement
• Robust	control	driving	down	prevalence	in	infected	herds
• Effective	protection	for	low	prevalence	herds
• Provide	platform	of	decreasing	prevalence	if	a	more	
structured	program	is	required	in	the	future
References
www.myhealthyherd.com
www.actionjohnes.org
• Orpin	P.G,	Sibley	R.J,Komorowski E	(2012)	.	A	voluntary	Johne's	
engagement	programme	in	UK	dairy	herds	3rd ParaTB Forum
• Orpin	P.G,	Sibley	R.J.(2014)A	Review	on	Progress	with	Johne's	
Engagement	Program	in	UK	Dairy	Herds.	4th ParaTB forum
• Sibley	.R.J,	Orpin	P.G	(2016)	The	National	Johnes Management	
Plan:	a	national	programme	for	the	management	of	
paratuberculosis in	the	UK	dairy	herd.5th ParaTB Forum
Questions
Questions

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