Doctors describe better coronary care methods

1. Doctors describe better
coronary care methods
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2. Contd…
Used in heart-care (coronary) and peripheral procedures, stents prevent or
treat the narrowing and blocking of arteries due to disease or injury . While
the use of stents has been largely successful, there are few limitations
associated with them. Restenosis, or the reoccurrence of vessel narrowing
after stent ing, is a common side effect resulting from the body's natural
response to a foreign object in the blood vessels. The first generation stents
were Bare Metal Stents (BMS) and had a 20 30% higher incidence of in stent
re stenosis (ISRs) in the short term.
Some cases also developed thrombosis (clotting). Later, drug-eluting stents
(DES) were introduced that delayed stenosis, to overcome the drawbacks of
BMS. In 2006, however, a potential safety issue emerged with reports linking
DES with the increased risk of late blood clotting. The culprit was thought to
be the polymer in the DES which could cause inflammation and could delay
vessel healing.
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3. Contd…
To address this issue and in an end eavor to deliver the best treatment
options to patients, alternative ap proaches such as drug-eluting stents with
bio-absorbable polymers were developed and have recently hit the market.
This stent technology pro vides the best of both worlds to pa tients, where
once drug elution is complete; the polymer completely goes away , leaving
behind a BMS. The SYNERGY stent system is the only such FDA approved
clinically proven solution available today that has ultrathin stent struts with
an abluminal bio-absorbable polymer coating technology which is absorbed
shortly after drug elution is complete at three months. This helps eliminate
longterm polymer exposure.
Dr (Prof) DS Gambhir, group director, Cardiology , Kailash Group of Hospitals,
says, “In a very complex group of 100 patients, the SYNERGY Stent showed
0% stent thrombosis at 12 months despite 77% of the patients discontinuing
DAPT at 3 months, as revealed during TCT2015.“
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4. Contd…
According to Dr TS Kler, executive director, Fortis Escorts, “This next
generation stent technology is designed with the goal of providing
optimal healing for improved patient care, ideal for dealing with
complex cases of coronary artery disease.SYNERGY stent's unique bio-
absorbable medicated coating prevents the potential side-effects of
long term polymer exposure, thereby providing excellent clinical
outcomes. Published studies have also seen chances of recurrence of a
clot within the stent in only 0.4% patients.“
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