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The Importance of CBD Gummy for the Health
CBD stands for gummy, which is cannabidiol. It is used to treat different symptoms, although its use is
controversial. There’s also some confusion that our bodies are affected by gummy. The CBD is
synergistic, which means it could have health benefits and is now legally permitted in many areas.
Therefore, read this essential aspect to get further info.
Cannabidiol, or CBD for short, is a component of the cannabis plant that has been exploding in
popularity due to the
many purported health benefits that it provides. So what is CBD? Does it really work or is it just a
placebo? Let’s take a look at what the research says and find out.
There’s a lot of CBD jargon. Help me navigate that.
There are several terms associated with CBD that are important to understand. They include:
CBD Isolate: This form contains only CBD and all of the plant matter, such as gummys, waxes,
chlorophyll, and others, is stripped away from it. This was once believed to be the most potent form of
CBD, but that’s not entirely true.
Broad-Spectrum CBD: This means naturally occurring compounds found inside the gummy are
preserved. However, the small amount of THC inside is removed. Broad-spectrum CBD’s additional
natural compounds can potentially offer therapeutic benefits, too.
Full-Spectrum CBD: This form contains all cannabinoids naturally found in the hemp or marijuana
plant, including trace amounts of THC. This broader range of natural compounds can also provide
additional health support.
HERE IS A COMPLETE LIST OF CBD GUMMY BENEFITS:
1. MAY RELIEVE PAINS: CHRONIC PAIN
CBD products have been found to help relieve or reduce pains ranging from minor to severe relief based on the strength and
concentration of the CBD product used.
Studies of CBD gummy ingestion suggest that CBD is beneficial for pain relief.
One study on pain relief from incision cuts found that rats had less pain specifically caused by cuts or incisions after using
CBD. Rats that were given CBD gummy in a non-rewarding way, wanted to take more CBD gummy as a reward, presuming
that rats wanted more because “of pain relief or reduction of pain aversiveness.” This study concluded that the effects of
CBD could play a role in pain relief.
1. A study from 2012 analyzed the effects of CBD on chronic pain, or more specifically neuropathic and
spinal pain stated “we report that system and intrathecal [into the spinal cord] administration of cannabidiol (CBD)…
significantly suppress chronic inflammatory and neuropathic pain without causing apparent analgesic tolerance [increased
tolerance against CBD] in rodents.”
What this means is that rodents were able to receive pain relief without building an increased tolerance against CBD,
therefore each daily dose did not become less effective over time. Which is good news for
human consumption. However, human studies need to be done to make any conclusion. Based on this evidence,
the benefits guide goes as follows.
500mg CBD products: Minor pain relief
1000mg CBD products: Moderate pain relief
1500mg CBD products: Severe pain relief
2.MAY REDUCE ANXIETY AND SOCIAL ANXIETY DISORDER (SAD)
A study published in 2010 tried to study the difference in effects of CBD and placebo for Social Anxiety Disorder
using neuroimaging to analyze differences in blood flow in the brain. With a daily oral dose of CBD gummy
400mg, the study found that CBD had a significant effect on subjective anxiety. The study concludes and suggests
that CBD does have an effect on SAD and a reduction in anxiety.
Another study tested subjects who were given a task of a “Simulated Public Speaking” test to test if CBD helps
with Public Speaking anxiety. The study gave the subjects 300mg of CBD, which was tested against four other
“drugs” in a double-blind test.
After the testing was complete, they analyzed the subjects and found that CBD “decreased anxiety after the SPS
test.” This means that the CBD helped reduce anxiety caused by the simulated public speaking test. The test
concludes by suggesting that CBD has anxiolytic (anxiety-reducing) properties in human volunteers submitted to a
stressful situation.
3.MAY HELP REDUCE FEAR REACTION OR EFFECTS
A study (Musty 2005) on CBD for fear was tested on rats and found that 40mg of CBD helped rats in fear. CBD
may have pharmacological effects as an antagonist of the CB1 receptor, which affects fear too. Noting that context
of the type of stress, anxiety, and fear has an effect on the anti-anxiety effect.
Another study (Front Pharmacol. 2016) on fear treatment using CBD found four ways that CBD helps fear.
Cannabidiol (CBD) decreases fear expression acutely
This is how, or the ways in which people show their fear. The study found no dosage dependency for effects.
Cannabidiol disrupts memory reconsolidation (re-remembered), leading to sustained fear attenuation
(reduction) upon memory retrieval.
This aid in fear also may help PTSD as well. When traumatic memories are remembered, they are stored as
“important” by the brain. By this statement, CBD could disrupt this process, and eventually lead to less severe
negative memories being processed.
Cannabidiol enhances extinction, the psychological process by which exposure therapy inhibits learned to
fear.
This was related to helping fight fear, through exposure. In which CBD could help improve the therapeutic healing
process.
Auditory fear expression is also reduced acutely by cannabidiol.
Meaning CBD has a possibility to reduce fear caused by sounds and noises. The study found that the dosage of
CBD for Auditory fear had to be a lot more than contextual fear.
The study notes that CBD is tested and has shown benefits for contextual fears (context matters). As well as states
that
other evidence indicates how CBD “modulates fundamental neurobiological processes” with Pavlovian fear
conditioning, which is learning the different environments and stimuli that are related to threats, and therefore
helping survival during fearful events.
The study concluded that CBD has found benefits for regulating “learned fear” which includes PTSD, in which
something feels dangerous because it was trained to be felt dangerous, although the encounter is not exactly
possible. Such as a fear of Great White sharks at the beach without ever actually interacting or being threatened by
one. CBD is suggested to reduce this fear until it is no longer present by “regulating learned fear by dampening its
expression, disrupting its reconsolidation, and facilitating its extinction.”
4. MAY REDUCE DEPRESSION & INCREASE MOOD
By virtue of being to inhibit anxiety, CBD has been also found to help depression by relieving depression-like
symptoms.
A study (Epub 2015) on the specific effects of CBD on depression found results that “CBD exerts fast and
maintained antidepressant-like effects as evidenced by the reversal of the OBX-induced hyperactivity and
anhedonia.”
Anhedonic symptoms include a lack of enjoyment of things that weren’t caused by any type of physiological
disease.
Examples of this would include financial problems, overworking, or family issues.
An example of hyperactivity is ADHD. Where based on the results, CBD may be able to help people with ADHD.
This is also a stretch and is not backed up by any substantial evidence.
The CBD helps depression by enhancing the signals of serotonin and glutamate a specific receptor mechanism (5-
HT1A).
5. MAY REDUCE STRESS
Also in similar terms, as CBD helping depression, there is plenty of evidence suggesting that CBD can be great for
stress as well.
CBD for stress works the same way as it does for anxiety, depression, mood, and other neuro-related effects by affected the
Cannabinoid receptors in our brain. Specifically the CB1 and CB2 receptors. Through these receptors, CBD was found to
help decrease traumatic and chronic stress in both human and animal studies.
Through the research on anxiety, it was found that CBD helps post-event for anxiety. On that note, CBD would help
after stress-inducing situations occur. Such as car accidents, job firings, or tragic events. However, more research still needs
to be conducted before any definitive conclusion can be made for stress specifically.
An additional study from May 2019 of 42 heroin-addicted adults found that 800mg of CBD lowered stress hormone, heart
rate, and cortisol levels compared to adults who were not taking CBD.
6.IT MAY HELP SLEEP INSOMNIA
CBD has been shown to help improve the symptoms of insomnia (Russo et all 2007).
A brand new study from January of 2019 studied 75 subjects who stated issues with sleep insomnia or anxiety. Those with
anxiety were given a 50mg-75mg dosage of CBD every night after dinner and before bed for over a month. The study found
that 66% of these people found that CBD helped their sleep improved over that month.
The CBD was given to them in capsule form. Sleep insomnia is one of the main proponents of using CBD, and there is
decent evidence and studies showing CBD benefits for sleep.
7.MAY WORK AS AN ANTIOXIDANT:
In combination with THC, CBD was found to have “neuroprotective antioxidant properties (Hamps on et al 1998).
8.MAY HELP REDUCE SYMPTOMS OF PTSD
For a more in-depth view of how CBD can help PTSD as well as Veterans with anxiety.
However, one study (Das et al. 2013) that was not included in that article was a human study that found that CBD only
helped those who had recovered from PTSD naturally and took CBD consistently after. In other words, CBD only worked to
help prevent future recurrences of PTSD after someone had stopped having visual memories with fear. Not before.
This study is not completely proven, but there are a few other cases that found a similar result.
The study concluded that CBD has the possibility to be a better treatment than current solutions available for PTSD and
other phobias. Including benzodiazepines. While also having fewer side effects than antidepressants.
9.CBD MAY HELP FIBROMYALGIA
The evidence that CBD helps fibromyalgia is limited and inconclusive. The only real evidence supporting this are customer
reviews who have found benefits for fibromyalgia, and also supporting evidence of inflammation and cbd pain relief in
general.
By helping decrease inflammation, CBD is likely to also help issues caused by fibromyalgia.
One study from 2006 did find evidence for a theory that a lack of overall endocannabinoids in the brain is possible to cause
issues such as fibromyalgia, migraines, irritable bowel, and other “treatment-resistant” symptoms. These neurotransmitter
deficiencies are able to possibly elevate these symptoms.
In that case, CBD would restore these deficiencies as CBD is bound to those receptors in the brain. The article suggests that
Cannabis is a possible solution for Fibromyalgia, as well as migraines.
10.MAY HELP RELIEVE CANCER PAINS & CANCER-RELATED SYMPTOMS
A study of 177 people that had intractable (chronic with no known cure) pain caused by cancers that are not responsive to
opiates showed that Sativex produced statistically significant evidence for relieving the pain while an almost pure THC
extraction did not show any significant pain relief. This evidence proposes that CBD may have been valuable for providing
pain relief for cancer-related pain.
Additionally, in two other studies from 2005 and 2006 ((Kogan; Ligresti et al), CBD and THC combined were able to
destroy the growth of malignant (deadly) cells as well as prevent cancer-created cells from developing.
In 2007, a drug that is almost equal THC to CBD in a ratio called Sativex was approved as a treatment for intractable
cancer pain. Intractable pains are constant pains that have not been found to be cured by anything. CBD attaches to receptors
in the ECS system, that control the central nervous system such as the brain, as well as the peripheral nervous system. Initial
research has found that this binding has found relief benefits for this type of cancer pain. The evidence is still minor, but
there these studies provide optimism for how CBD may help cancer.
11.MAY HELP WITH YOGA, MEDITATION, FITNESS, & SPORTS
Because of the benefits of CBD found for pain relief, inflammation, as well as anxiety, and sleep insomnia, there is a large
sector of athletes and amateurs alike who have turned to CBD relief to help with their symptoms. Athletes in all facets of
sports have started using CBD to help with post-workout and recovery training.
Especially with injuries as shown by the benefits of inflammation and pain relief. Professionals and amateur athletes are
using CBD to get ahead. And it’s working. As well, CBD and Yoga are becoming very popular because of their similar
functionality and usefulness for those who want to relax and clear their minds.
12.MAY GIVE RELIEF FROM NAUSEA AND VOMITING
From another study in 2005 (Pertwee), it was found that CBD in addition to CBD can have effects that relieve nausea and
vomiting.
13.MAY HELP REDUCE INFLAMMATION (CHRONIC INFLAMMATORY)
Inflammation itself is an immune response from infections, illness, or injuries.
A study on rats with inflammatory pain was given a daily oral treatment of 20mg of CBD for a total time of 7-14 days after
injury. The study found that CBD gummy reduced the pain response and sensitivity to heat and physical stimuli, such as
touch. In other words, by decreasing the pain response or threshold, inflammation itself decreases.
What this means is that CBD gummy appears to reduce the way the body responds to these injuries. And instead of causing
inflammation, CBD gummy gives therapeutic benefits that decrease the body’s negative immune response. In a test [Exp
Dermatol. 2016] studying different compounds of cannabis including CBC, CBDV, CBG, CBGV and THCV noted that all
of these phytocannabinoids showed remarkable data for ‘anti-inflammatory actions.’
The study then concluded by stating that these cannabis compounds could be a ‘novel’ and ‘safe’ way for inflammation
caused by cutting of the skin. Such as injuries, puncture wounds, and sharp object cuts including knives. All of these
phytocannabinoids can be found in our full-spectrum CBD gummy tinctures here. Non-spectrum gummys are labeled (THC-
Free).
14.IT MAY HELP NERVE PAIN
The same study that found the benefits of CBD for inflammation pain, also found that daily oral treatment of 2.5mg- 20mg
of CBD to rats for 14 days after nerve pain issues seemed to relieve the pain. Stating that there is a “potential for the
therapeutic use of cannabidiol in chronic painful states.”
15.MAY REDUCE ACNE & DRY-SKIN SYNDROME: NATURAL ANALGESIC
CBD has been found to help reduce acne as a complementary benefit to its anti-inflammatory properties.
A study [J Clin Invest. 2014] found that CBD affects the sebaceous gland, which is the gland in the skin that controls the
secretion of lubricating gummyy matter (sebum) in which hair follicles get stuck in to create acne.
The study found that CBD inhibited the secretion of this gummyy matter from the sebaceous gland, therefore limiting acne
formation.
Additionally, the continuation of this study [Exp Dermatol. 2016] found that CBD “exerted complex anti-acne effects by
normalizing ‘pro-acne agents’ within decreasing gummy reproduction.
The continuation also studied the anti-inflammatory and Acne treatment effects of other Cannabis Sativa compounds,
including CBC, CBG, CBGV, CBDV, and THCV.
Their data found evidence that CBGV and CBG could be agents for dry-skin syndrome and CBC, THCV, and CBDV
show high efficiency as anti-acne agents. Stating that they have a high potential for being an acne solution.
16.IT MAY HELP MULTIPLE SCLEROSIS
CBD has been found through clinical studies to help Multiple Sclerosis (MS). A product called Sativex, which consists of an
equal ratio of Tetrahydrocannabinol (THC) and CBD was approved in Canada in 2005 as a treatment
for neuropathic pain in MS, as CBD binds to those receptors with endocannabinoid modulating effects.
Noted in a study, they found that CBD in combination with THC helps prevent the negative effects of THC such as anxiety,
panic, intoxication, increased heart rate, and the “high” effect.
17.MAY HELP ARTHRITIS (RHEUMATOID)
CBD was analyzed on a rodent model and was found to inhibit inflammation with rheumatoid arthritis. However, this study
lacks a human model comparison.
In one randomized, double-blind human study using a Placebo and Sativex, they had 56 patients use the products only
at night before bed with almost an equal ratio of CBD and THC (15mg) for 5 weeks. At the end of the study, it was found
that the Sativex was preferred over the placebo in terms of morning arthritis pain during rest and movement.
18.IT MAY HELP MIGRAINES AND CHRONIC HEADACHES
After much research, there is only one conclusive piece of evidence regarding CBD for migraines. It happens to be an
impressive study executed by Italy, and presented to the 3rd Congress of the European Academy of Neurology (EAN) in
2017.
The study was committed on 48 chronic migraine volunteers. They gave those volunteers a combination of two compounds,
one containing 19% THC and the other containing 0% THC and 9% CBD, for a period of three months. Starting with 10mg
of the total dosage. The study noted no beneficial effects were noticed until 100mg, and then at 200mg found a 55%
decrease in acute pain from migraines and chronic headaches!
They found that the relief effect of the Cannabis compound combination to be in line with other migraine treatments,
however, they also noticed a 43.5% reduction in acute pain intensity from migraines as well. Unlike the other treatments.
This is possibly due to the effect that CBD has on the brain and neurotransmitters, in contrast to other treatments which
don’t work the same way THC-CBD does.
The one caveat of this study is that they only noticed that the combination is only effective in those individuals who have
been dealing with migraines and chronic headaches since childhood. Stating that it does not improve relief more than other
treatments in people without previous history.
The study concludes very few CBD side effects on migraines other than occasional drowsiness and difficulty
concentrating. This is interesting as CBD has been found to help concentration in others.
Overall, the study on migraines is fairly conclusive, however, there is no such thing as too much research. More studies are
likely to be completed within the next few years to confirm or contradict these findings.
19. SEIZURES & EPILEPSY TREATMENT:
Just last year in 2018, the first FDA-approved CBD treatment for two rare conditions of seizures and epilepsy called
Epidiolex. In case you are wondering or may need the use of the treatment, it costs a hefty price of $32,500 per year and
contains
1.Lennox-Gastaut Syndrome: Occurs in early childhood, with the average ages being between 3-5 years old.
2.Dravet Syndrome: Occurs within the first year of life with ‘fever-related seizures.
This was a huge step in medical treatment as the first approved treatment for Dravet Syndrome. According
to FDA.gov, “Epidiolex’s effectiveness was studied in three randomized, double-blind, placebo-controlled clinical trials
involving 516 patients with either Lennox-Gastaut syndrome or Dravet syndrome. Epidiolex, taken along with other
medications, was shown to be effective in reducing the frequency of seizures when compared with placebo.” Epidiolex was
found to decrease seizure rate by 42%. Side effects from the treatment included lethargy, sedation, and sleepiness. For CBD
gummy-related side effects.
Epidiolex contains 100mg/ml of CBD, as well as “dehydrated alcohol, sesame seed gummy, strawberry flavor, and
sucralose.”
20. IT MAY HELP DECREASE CIGARETTE SMOKING HABITS
This one relates more to De lta 8 Disposable Vape more than CBD gummy itself, however a study [Addict Behav. 2013]
found a 40% decrease in cigarette use when test a placebo and CBD vape product.
The study was a randomized double-blind test of 24 nicotine-addicted smokers. The study concluded that there was strong
evidence of CBD curbing nicotine addiction, and added more studies should be explored.
21. MAY HELP DRUG (OPIOID) WITHDRAWAL & ADDICTION
Initial CBD studies [Neurotherapeutics. 2015] found that CBD helps inhibit ‘drug-seeking behavior with virtually no
possibility of abuse or over-use.
22. DIGESTIVE AID
The Endocannabinoid System (ECS) also has major proponents within normal digestive and gut function. Things such as
inflammation, bowel disease, and gut permeability all run through this system.
CBD has shown beneficial effects for anti-inflammation, which may show positive potential for digestive aid. A doctor
stated, “it’s interesting to note that deficiencies in the ECS are associated with pathological states including
irritable bowel syndrome (IBS), colorectal cancer, and celiac disease.”
By working through the ECS system, CBD can play a role in gut-related functions.
23. MUSCLE RELAXER AND MAY SPEED UP MUSCLE RECOVERY
CBD Creams are becoming more and more popular within fitness, gym, and sports cultures. For good reason. The ECS also
plays a major role within muscle chemical messages from the Central Nervous System (CNS). The more chemical messages
sent to the muscles to contract, the more “stuff” the muscle becomes. CBD can aid in decreasing the number of messengers
sent to muscles, thereby helping muscle relaxation.
This means that rubbing CBD Pain c re ams on your muscles post-exercise or workout could help them relax, decrease
muscle stiffness, decrease recovery time, decrease muscle breakdown feeling, and decreasing injury to over-worked muscles.
The amount of athletes using CBD creams has multiplied within the last few years for this reason.
24. MIGHT HAVE NEUROPROTECTIVE PROPERTIES
There is plentiful evidence backing up CBD’s ability as a neuroprotective agent. One document noted that CBD encourages
neuroplasticity, the growth of new neurons in the brain, therefore decreasing the brain’s deterioration. CBD may protect
against damages from “ischemia, traumatic blows, or autoimmune and genetic disorders” and also help recovery from them.
This is also may suggest cannabidiol’s possible effectiveness in helping brain traumas or injuries. By push neuron
regeneration and healing. Another study [Surg Neurol Int. 2018] found that CBD might help with brain damage,
degenerative diseases, and inflammation specifically. Which also ties into neurobehavior and improvements. This study
identifies the effectiveness of CBD paired with THC to possibly increase benefits.
An additional older study [Pediatr Res. 2008] concluded with a suggestion stating, “CBD administration was associated with
cardiac, hemodynamic, and ventilatory beneficial effects. In conclusion, administration of CBD after HI reduced short-term
brain damage and was associated with extracerebral benefits.” This study suggests similar conclusions as other studies, with
CBD being a beneficial agent as short-term aid for multiple symptoms.
Therapeutic effects of CBD have taken 4-6 weeks of constant use to start seeing any clinical effects.
Another study summarized, “cannabinoids can be neuroprotective via their immunomodulatory properties, which have been
mainly attributed to CB2 receptors.” These are receptors that have a major effect on our immune system, and overall body
health for fighting diseases.
25.MAY BENEFIT HEART HEALTH
Cardiovascular health is another topic that has been explored with the benefits of CBD and CBD gummy products. A study
[Br J Clin Pharmacol. 2013] found evidence suggesting that CBD affects platelet aggregation, as well as the death and
survival of white blood cells in the blood.
The study found that CBD reduced vascular tension by 40% as a maximum of a pre-existing conditions. This includes human
arteries, involving CB1 receptor activation.
This study included additional information from a previous pieces of research suggesting that the cardioprotective benefits of
CBD are likely due to immune control effects than actual heart benefits.
The study also found that after conduction research on rats, that CBD increased CBF, which significantly affects and
decreases the probability of a stroke. A decrease in CBF shows great relevance to strokes.
The studies are preliminary and are most representative of rats. However, they provide positive evidence of the possible
effects on humans.
26.MAY REDUCE RISK OF DIABETES AND OBESITY
By virtue of aiding chronic inflammation, cannabidiol has shown hope in helping with type 2 diabetes and insulin resistance.
A scientist named Mark Rosenfeld stated, “unlike insulin and other medications for diabetes, CBD may actually suppress,
reverse and perhaps cure the disease [diabetes].
There is little cold-hard evidence for this, but it is a possible side effect of high dosages of CBD gummy.
27.IMMUNOMODULATORY EFFECTS
CBD is shown to have potent effects in internal body controls, [Biochem Pharmacol. 2008] and shows significant evidence
for increasing the activation of cells that control immune response and health (T cells). CBD gives evidence of increasing the
magnitude of specific cell function responses that increase immune system benefits and modulation. Therefore improving
immune function.
Another study found evidence that the way CBD affects the cannabinoid receptor 2 (CB2) lends to the potential of how
cannabidiol may help modulate the immune system. The study acknowledges clear evidence that CBD helps
immunomodulation during the inflammation process, and that CBD may affect it in four ways. This includes inducing the
normal death cycle of cells, decreasing cell creation vs death (increased for tumors), producing more anti- inflammatory
agents, and creating more regulatory T cells.
Targeting CB2 is cited as a possible revolutionary approach to the treatment of autoimmune and inflammatory diseases.
28.POTENTIAL IN TREATMENT OF HIV-1 INFECTION
The boost that CBD may have as anti-inflammatory shows additional possible benefits in boosting immune cell agents
against HIV-1. The way CBD works with the CB2 cell provides immune therapeutic possibilities to fight dysfunctional HIV-
1 cells.
Using human and animal models, multiple studies found that cannabidiol deactivates important HIV-1 cells, and
through CB2 agonists, decreased HIV replication. The same study document noted that THC also has benefits against HIV-1
infection.
29.CBD IS AN EFFECTIVE TREATMENT FOR HEROIN ADDICTION:
A new study just released in May of 2019 found intense cravings are the leading cause for drug use, and any substance that
reduces this craving may reduce the chance of overdose and relapse.
The study took 42 adults with an average heroin use of 13 years and divided them into three groups to take 800mg of CBD,
400mg of CBD, and placebo respectively.
Each adult was given the dosage once daily for 3 days consecutively and was studied for the next two weeks. During
this time, they were shown pictures of nature along with pictures of heroin-related items such as syringes and then were
asked to state their anxiety levels.
The study found that the adults who were taking CBD showed a 2-3x reduction in heroin cravings in contrast to the
placebo group. The study also showed that the difference between the CBD groups was insignificant.
30.OSTEOARTHRITIS (OA) JOINT & NEUROPATHIC PAIN:
Osteoarthritis (OA) is a joint disease that has many facets and effects, such as intermittent inflammation, joint degeneration,
and peripheral neuropathy.
A new study from 2017 wanted to find if CBD stopped the inflammation that ends up causing Osteoarthritis and neuropathy
pain. Additionally, they wanted to analyze CBD’s anti-nociceptive properties (the ability to block the
feeling or detection of the injurious or painful stimulus of sensory neurons). Or in less complicated terms, the ability of CBD
to stop us from feeling pain or injuries.
In order to study this, the doctors induced Osteoarthritis in male rats and then used dosing of CBD to see the effective
results. The study found that in end-stage OA, the CBD reduced acute and transient joint inflammation. They also found
CBD to be neuroprotective. Meaning, it helps prevent our brains and senses from feeling the discomfort caused by OA.
The data from this study indicated that oral administration of CBD blocked OA pain.
Concluding that CBD treatment prevented the later development of pain and nerve damage in OA joints and that
CBD may be a safe and useful therapy for treating OA joint neuropathic pain.
31. INCREASED EFFECTIVENESS:
CBD has been found to have the opposite effect of tolerance, with an increase in effectiveness over time. Therefore, the
benefits of CBD may still occur even with a smaller dosage of the same product. Every month or two, you should decrease
your dosage of CBD to see if you still receive your desired effects.

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The importance of cbd gummy

  • 1. The Importance of CBD Gummy for the Health CBD stands for gummy, which is cannabidiol. It is used to treat different symptoms, although its use is controversial. There’s also some confusion that our bodies are affected by gummy. The CBD is synergistic, which means it could have health benefits and is now legally permitted in many areas. Therefore, read this essential aspect to get further info. Cannabidiol, or CBD for short, is a component of the cannabis plant that has been exploding in popularity due to the many purported health benefits that it provides. So what is CBD? Does it really work or is it just a placebo? Let’s take a look at what the research says and find out. There’s a lot of CBD jargon. Help me navigate that. There are several terms associated with CBD that are important to understand. They include: CBD Isolate: This form contains only CBD and all of the plant matter, such as gummys, waxes, chlorophyll, and others, is stripped away from it. This was once believed to be the most potent form of CBD, but that’s not entirely true. Broad-Spectrum CBD: This means naturally occurring compounds found inside the gummy are preserved. However, the small amount of THC inside is removed. Broad-spectrum CBD’s additional natural compounds can potentially offer therapeutic benefits, too. Full-Spectrum CBD: This form contains all cannabinoids naturally found in the hemp or marijuana plant, including trace amounts of THC. This broader range of natural compounds can also provide additional health support. HERE IS A COMPLETE LIST OF CBD GUMMY BENEFITS: 1. MAY RELIEVE PAINS: CHRONIC PAIN CBD products have been found to help relieve or reduce pains ranging from minor to severe relief based on the strength and concentration of the CBD product used. Studies of CBD gummy ingestion suggest that CBD is beneficial for pain relief. One study on pain relief from incision cuts found that rats had less pain specifically caused by cuts or incisions after using CBD. Rats that were given CBD gummy in a non-rewarding way, wanted to take more CBD gummy as a reward, presuming that rats wanted more because “of pain relief or reduction of pain aversiveness.” This study concluded that the effects of CBD could play a role in pain relief. 1. A study from 2012 analyzed the effects of CBD on chronic pain, or more specifically neuropathic and spinal pain stated “we report that system and intrathecal [into the spinal cord] administration of cannabidiol (CBD)… significantly suppress chronic inflammatory and neuropathic pain without causing apparent analgesic tolerance [increased tolerance against CBD] in rodents.” What this means is that rodents were able to receive pain relief without building an increased tolerance against CBD, therefore each daily dose did not become less effective over time. Which is good news for
  • 2. human consumption. However, human studies need to be done to make any conclusion. Based on this evidence, the benefits guide goes as follows. 500mg CBD products: Minor pain relief 1000mg CBD products: Moderate pain relief 1500mg CBD products: Severe pain relief 2.MAY REDUCE ANXIETY AND SOCIAL ANXIETY DISORDER (SAD) A study published in 2010 tried to study the difference in effects of CBD and placebo for Social Anxiety Disorder using neuroimaging to analyze differences in blood flow in the brain. With a daily oral dose of CBD gummy 400mg, the study found that CBD had a significant effect on subjective anxiety. The study concludes and suggests that CBD does have an effect on SAD and a reduction in anxiety. Another study tested subjects who were given a task of a “Simulated Public Speaking” test to test if CBD helps with Public Speaking anxiety. The study gave the subjects 300mg of CBD, which was tested against four other “drugs” in a double-blind test. After the testing was complete, they analyzed the subjects and found that CBD “decreased anxiety after the SPS test.” This means that the CBD helped reduce anxiety caused by the simulated public speaking test. The test concludes by suggesting that CBD has anxiolytic (anxiety-reducing) properties in human volunteers submitted to a stressful situation. 3.MAY HELP REDUCE FEAR REACTION OR EFFECTS A study (Musty 2005) on CBD for fear was tested on rats and found that 40mg of CBD helped rats in fear. CBD may have pharmacological effects as an antagonist of the CB1 receptor, which affects fear too. Noting that context of the type of stress, anxiety, and fear has an effect on the anti-anxiety effect. Another study (Front Pharmacol. 2016) on fear treatment using CBD found four ways that CBD helps fear. Cannabidiol (CBD) decreases fear expression acutely This is how, or the ways in which people show their fear. The study found no dosage dependency for effects. Cannabidiol disrupts memory reconsolidation (re-remembered), leading to sustained fear attenuation (reduction) upon memory retrieval. This aid in fear also may help PTSD as well. When traumatic memories are remembered, they are stored as “important” by the brain. By this statement, CBD could disrupt this process, and eventually lead to less severe negative memories being processed. Cannabidiol enhances extinction, the psychological process by which exposure therapy inhibits learned to fear. This was related to helping fight fear, through exposure. In which CBD could help improve the therapeutic healing process. Auditory fear expression is also reduced acutely by cannabidiol. Meaning CBD has a possibility to reduce fear caused by sounds and noises. The study found that the dosage of CBD for Auditory fear had to be a lot more than contextual fear. The study notes that CBD is tested and has shown benefits for contextual fears (context matters). As well as states that other evidence indicates how CBD “modulates fundamental neurobiological processes” with Pavlovian fear conditioning, which is learning the different environments and stimuli that are related to threats, and therefore helping survival during fearful events. The study concluded that CBD has found benefits for regulating “learned fear” which includes PTSD, in which something feels dangerous because it was trained to be felt dangerous, although the encounter is not exactly possible. Such as a fear of Great White sharks at the beach without ever actually interacting or being threatened by one. CBD is suggested to reduce this fear until it is no longer present by “regulating learned fear by dampening its expression, disrupting its reconsolidation, and facilitating its extinction.” 4. MAY REDUCE DEPRESSION & INCREASE MOOD By virtue of being to inhibit anxiety, CBD has been also found to help depression by relieving depression-like symptoms. A study (Epub 2015) on the specific effects of CBD on depression found results that “CBD exerts fast and maintained antidepressant-like effects as evidenced by the reversal of the OBX-induced hyperactivity and anhedonia.” Anhedonic symptoms include a lack of enjoyment of things that weren’t caused by any type of physiological disease. Examples of this would include financial problems, overworking, or family issues. An example of hyperactivity is ADHD. Where based on the results, CBD may be able to help people with ADHD. This is also a stretch and is not backed up by any substantial evidence. The CBD helps depression by enhancing the signals of serotonin and glutamate a specific receptor mechanism (5- HT1A). 5. MAY REDUCE STRESS Also in similar terms, as CBD helping depression, there is plenty of evidence suggesting that CBD can be great for stress as well.
  • 3. CBD for stress works the same way as it does for anxiety, depression, mood, and other neuro-related effects by affected the Cannabinoid receptors in our brain. Specifically the CB1 and CB2 receptors. Through these receptors, CBD was found to help decrease traumatic and chronic stress in both human and animal studies. Through the research on anxiety, it was found that CBD helps post-event for anxiety. On that note, CBD would help after stress-inducing situations occur. Such as car accidents, job firings, or tragic events. However, more research still needs to be conducted before any definitive conclusion can be made for stress specifically. An additional study from May 2019 of 42 heroin-addicted adults found that 800mg of CBD lowered stress hormone, heart rate, and cortisol levels compared to adults who were not taking CBD. 6.IT MAY HELP SLEEP INSOMNIA CBD has been shown to help improve the symptoms of insomnia (Russo et all 2007). A brand new study from January of 2019 studied 75 subjects who stated issues with sleep insomnia or anxiety. Those with anxiety were given a 50mg-75mg dosage of CBD every night after dinner and before bed for over a month. The study found that 66% of these people found that CBD helped their sleep improved over that month. The CBD was given to them in capsule form. Sleep insomnia is one of the main proponents of using CBD, and there is decent evidence and studies showing CBD benefits for sleep. 7.MAY WORK AS AN ANTIOXIDANT: In combination with THC, CBD was found to have “neuroprotective antioxidant properties (Hamps on et al 1998). 8.MAY HELP REDUCE SYMPTOMS OF PTSD For a more in-depth view of how CBD can help PTSD as well as Veterans with anxiety. However, one study (Das et al. 2013) that was not included in that article was a human study that found that CBD only helped those who had recovered from PTSD naturally and took CBD consistently after. In other words, CBD only worked to help prevent future recurrences of PTSD after someone had stopped having visual memories with fear. Not before. This study is not completely proven, but there are a few other cases that found a similar result. The study concluded that CBD has the possibility to be a better treatment than current solutions available for PTSD and other phobias. Including benzodiazepines. While also having fewer side effects than antidepressants. 9.CBD MAY HELP FIBROMYALGIA The evidence that CBD helps fibromyalgia is limited and inconclusive. The only real evidence supporting this are customer reviews who have found benefits for fibromyalgia, and also supporting evidence of inflammation and cbd pain relief in general. By helping decrease inflammation, CBD is likely to also help issues caused by fibromyalgia. One study from 2006 did find evidence for a theory that a lack of overall endocannabinoids in the brain is possible to cause issues such as fibromyalgia, migraines, irritable bowel, and other “treatment-resistant” symptoms. These neurotransmitter deficiencies are able to possibly elevate these symptoms. In that case, CBD would restore these deficiencies as CBD is bound to those receptors in the brain. The article suggests that Cannabis is a possible solution for Fibromyalgia, as well as migraines. 10.MAY HELP RELIEVE CANCER PAINS & CANCER-RELATED SYMPTOMS A study of 177 people that had intractable (chronic with no known cure) pain caused by cancers that are not responsive to opiates showed that Sativex produced statistically significant evidence for relieving the pain while an almost pure THC extraction did not show any significant pain relief. This evidence proposes that CBD may have been valuable for providing pain relief for cancer-related pain. Additionally, in two other studies from 2005 and 2006 ((Kogan; Ligresti et al), CBD and THC combined were able to destroy the growth of malignant (deadly) cells as well as prevent cancer-created cells from developing. In 2007, a drug that is almost equal THC to CBD in a ratio called Sativex was approved as a treatment for intractable cancer pain. Intractable pains are constant pains that have not been found to be cured by anything. CBD attaches to receptors in the ECS system, that control the central nervous system such as the brain, as well as the peripheral nervous system. Initial research has found that this binding has found relief benefits for this type of cancer pain. The evidence is still minor, but there these studies provide optimism for how CBD may help cancer. 11.MAY HELP WITH YOGA, MEDITATION, FITNESS, & SPORTS Because of the benefits of CBD found for pain relief, inflammation, as well as anxiety, and sleep insomnia, there is a large sector of athletes and amateurs alike who have turned to CBD relief to help with their symptoms. Athletes in all facets of sports have started using CBD to help with post-workout and recovery training. Especially with injuries as shown by the benefits of inflammation and pain relief. Professionals and amateur athletes are using CBD to get ahead. And it’s working. As well, CBD and Yoga are becoming very popular because of their similar functionality and usefulness for those who want to relax and clear their minds. 12.MAY GIVE RELIEF FROM NAUSEA AND VOMITING
  • 4. From another study in 2005 (Pertwee), it was found that CBD in addition to CBD can have effects that relieve nausea and vomiting. 13.MAY HELP REDUCE INFLAMMATION (CHRONIC INFLAMMATORY) Inflammation itself is an immune response from infections, illness, or injuries. A study on rats with inflammatory pain was given a daily oral treatment of 20mg of CBD for a total time of 7-14 days after injury. The study found that CBD gummy reduced the pain response and sensitivity to heat and physical stimuli, such as touch. In other words, by decreasing the pain response or threshold, inflammation itself decreases. What this means is that CBD gummy appears to reduce the way the body responds to these injuries. And instead of causing inflammation, CBD gummy gives therapeutic benefits that decrease the body’s negative immune response. In a test [Exp Dermatol. 2016] studying different compounds of cannabis including CBC, CBDV, CBG, CBGV and THCV noted that all of these phytocannabinoids showed remarkable data for ‘anti-inflammatory actions.’ The study then concluded by stating that these cannabis compounds could be a ‘novel’ and ‘safe’ way for inflammation caused by cutting of the skin. Such as injuries, puncture wounds, and sharp object cuts including knives. All of these phytocannabinoids can be found in our full-spectrum CBD gummy tinctures here. Non-spectrum gummys are labeled (THC- Free). 14.IT MAY HELP NERVE PAIN The same study that found the benefits of CBD for inflammation pain, also found that daily oral treatment of 2.5mg- 20mg of CBD to rats for 14 days after nerve pain issues seemed to relieve the pain. Stating that there is a “potential for the therapeutic use of cannabidiol in chronic painful states.” 15.MAY REDUCE ACNE & DRY-SKIN SYNDROME: NATURAL ANALGESIC CBD has been found to help reduce acne as a complementary benefit to its anti-inflammatory properties. A study [J Clin Invest. 2014] found that CBD affects the sebaceous gland, which is the gland in the skin that controls the secretion of lubricating gummyy matter (sebum) in which hair follicles get stuck in to create acne. The study found that CBD inhibited the secretion of this gummyy matter from the sebaceous gland, therefore limiting acne formation. Additionally, the continuation of this study [Exp Dermatol. 2016] found that CBD “exerted complex anti-acne effects by normalizing ‘pro-acne agents’ within decreasing gummy reproduction. The continuation also studied the anti-inflammatory and Acne treatment effects of other Cannabis Sativa compounds, including CBC, CBG, CBGV, CBDV, and THCV. Their data found evidence that CBGV and CBG could be agents for dry-skin syndrome and CBC, THCV, and CBDV show high efficiency as anti-acne agents. Stating that they have a high potential for being an acne solution. 16.IT MAY HELP MULTIPLE SCLEROSIS CBD has been found through clinical studies to help Multiple Sclerosis (MS). A product called Sativex, which consists of an equal ratio of Tetrahydrocannabinol (THC) and CBD was approved in Canada in 2005 as a treatment for neuropathic pain in MS, as CBD binds to those receptors with endocannabinoid modulating effects. Noted in a study, they found that CBD in combination with THC helps prevent the negative effects of THC such as anxiety, panic, intoxication, increased heart rate, and the “high” effect. 17.MAY HELP ARTHRITIS (RHEUMATOID) CBD was analyzed on a rodent model and was found to inhibit inflammation with rheumatoid arthritis. However, this study lacks a human model comparison. In one randomized, double-blind human study using a Placebo and Sativex, they had 56 patients use the products only at night before bed with almost an equal ratio of CBD and THC (15mg) for 5 weeks. At the end of the study, it was found that the Sativex was preferred over the placebo in terms of morning arthritis pain during rest and movement. 18.IT MAY HELP MIGRAINES AND CHRONIC HEADACHES After much research, there is only one conclusive piece of evidence regarding CBD for migraines. It happens to be an impressive study executed by Italy, and presented to the 3rd Congress of the European Academy of Neurology (EAN) in 2017. The study was committed on 48 chronic migraine volunteers. They gave those volunteers a combination of two compounds, one containing 19% THC and the other containing 0% THC and 9% CBD, for a period of three months. Starting with 10mg of the total dosage. The study noted no beneficial effects were noticed until 100mg, and then at 200mg found a 55% decrease in acute pain from migraines and chronic headaches! They found that the relief effect of the Cannabis compound combination to be in line with other migraine treatments, however, they also noticed a 43.5% reduction in acute pain intensity from migraines as well. Unlike the other treatments. This is possibly due to the effect that CBD has on the brain and neurotransmitters, in contrast to other treatments which don’t work the same way THC-CBD does.
  • 5. The one caveat of this study is that they only noticed that the combination is only effective in those individuals who have been dealing with migraines and chronic headaches since childhood. Stating that it does not improve relief more than other treatments in people without previous history. The study concludes very few CBD side effects on migraines other than occasional drowsiness and difficulty concentrating. This is interesting as CBD has been found to help concentration in others. Overall, the study on migraines is fairly conclusive, however, there is no such thing as too much research. More studies are likely to be completed within the next few years to confirm or contradict these findings. 19. SEIZURES & EPILEPSY TREATMENT: Just last year in 2018, the first FDA-approved CBD treatment for two rare conditions of seizures and epilepsy called Epidiolex. In case you are wondering or may need the use of the treatment, it costs a hefty price of $32,500 per year and contains 1.Lennox-Gastaut Syndrome: Occurs in early childhood, with the average ages being between 3-5 years old. 2.Dravet Syndrome: Occurs within the first year of life with ‘fever-related seizures. This was a huge step in medical treatment as the first approved treatment for Dravet Syndrome. According to FDA.gov, “Epidiolex’s effectiveness was studied in three randomized, double-blind, placebo-controlled clinical trials involving 516 patients with either Lennox-Gastaut syndrome or Dravet syndrome. Epidiolex, taken along with other medications, was shown to be effective in reducing the frequency of seizures when compared with placebo.” Epidiolex was found to decrease seizure rate by 42%. Side effects from the treatment included lethargy, sedation, and sleepiness. For CBD gummy-related side effects. Epidiolex contains 100mg/ml of CBD, as well as “dehydrated alcohol, sesame seed gummy, strawberry flavor, and sucralose.” 20. IT MAY HELP DECREASE CIGARETTE SMOKING HABITS This one relates more to De lta 8 Disposable Vape more than CBD gummy itself, however a study [Addict Behav. 2013] found a 40% decrease in cigarette use when test a placebo and CBD vape product. The study was a randomized double-blind test of 24 nicotine-addicted smokers. The study concluded that there was strong evidence of CBD curbing nicotine addiction, and added more studies should be explored. 21. MAY HELP DRUG (OPIOID) WITHDRAWAL & ADDICTION Initial CBD studies [Neurotherapeutics. 2015] found that CBD helps inhibit ‘drug-seeking behavior with virtually no possibility of abuse or over-use. 22. DIGESTIVE AID The Endocannabinoid System (ECS) also has major proponents within normal digestive and gut function. Things such as inflammation, bowel disease, and gut permeability all run through this system. CBD has shown beneficial effects for anti-inflammation, which may show positive potential for digestive aid. A doctor stated, “it’s interesting to note that deficiencies in the ECS are associated with pathological states including irritable bowel syndrome (IBS), colorectal cancer, and celiac disease.” By working through the ECS system, CBD can play a role in gut-related functions. 23. MUSCLE RELAXER AND MAY SPEED UP MUSCLE RECOVERY CBD Creams are becoming more and more popular within fitness, gym, and sports cultures. For good reason. The ECS also plays a major role within muscle chemical messages from the Central Nervous System (CNS). The more chemical messages sent to the muscles to contract, the more “stuff” the muscle becomes. CBD can aid in decreasing the number of messengers sent to muscles, thereby helping muscle relaxation. This means that rubbing CBD Pain c re ams on your muscles post-exercise or workout could help them relax, decrease muscle stiffness, decrease recovery time, decrease muscle breakdown feeling, and decreasing injury to over-worked muscles. The amount of athletes using CBD creams has multiplied within the last few years for this reason. 24. MIGHT HAVE NEUROPROTECTIVE PROPERTIES There is plentiful evidence backing up CBD’s ability as a neuroprotective agent. One document noted that CBD encourages neuroplasticity, the growth of new neurons in the brain, therefore decreasing the brain’s deterioration. CBD may protect against damages from “ischemia, traumatic blows, or autoimmune and genetic disorders” and also help recovery from them. This is also may suggest cannabidiol’s possible effectiveness in helping brain traumas or injuries. By push neuron regeneration and healing. Another study [Surg Neurol Int. 2018] found that CBD might help with brain damage, degenerative diseases, and inflammation specifically. Which also ties into neurobehavior and improvements. This study identifies the effectiveness of CBD paired with THC to possibly increase benefits. An additional older study [Pediatr Res. 2008] concluded with a suggestion stating, “CBD administration was associated with cardiac, hemodynamic, and ventilatory beneficial effects. In conclusion, administration of CBD after HI reduced short-term brain damage and was associated with extracerebral benefits.” This study suggests similar conclusions as other studies, with CBD being a beneficial agent as short-term aid for multiple symptoms. Therapeutic effects of CBD have taken 4-6 weeks of constant use to start seeing any clinical effects.
  • 6. Another study summarized, “cannabinoids can be neuroprotective via their immunomodulatory properties, which have been mainly attributed to CB2 receptors.” These are receptors that have a major effect on our immune system, and overall body health for fighting diseases. 25.MAY BENEFIT HEART HEALTH Cardiovascular health is another topic that has been explored with the benefits of CBD and CBD gummy products. A study [Br J Clin Pharmacol. 2013] found evidence suggesting that CBD affects platelet aggregation, as well as the death and survival of white blood cells in the blood. The study found that CBD reduced vascular tension by 40% as a maximum of a pre-existing conditions. This includes human arteries, involving CB1 receptor activation. This study included additional information from a previous pieces of research suggesting that the cardioprotective benefits of CBD are likely due to immune control effects than actual heart benefits. The study also found that after conduction research on rats, that CBD increased CBF, which significantly affects and decreases the probability of a stroke. A decrease in CBF shows great relevance to strokes. The studies are preliminary and are most representative of rats. However, they provide positive evidence of the possible effects on humans. 26.MAY REDUCE RISK OF DIABETES AND OBESITY By virtue of aiding chronic inflammation, cannabidiol has shown hope in helping with type 2 diabetes and insulin resistance. A scientist named Mark Rosenfeld stated, “unlike insulin and other medications for diabetes, CBD may actually suppress, reverse and perhaps cure the disease [diabetes]. There is little cold-hard evidence for this, but it is a possible side effect of high dosages of CBD gummy. 27.IMMUNOMODULATORY EFFECTS CBD is shown to have potent effects in internal body controls, [Biochem Pharmacol. 2008] and shows significant evidence for increasing the activation of cells that control immune response and health (T cells). CBD gives evidence of increasing the magnitude of specific cell function responses that increase immune system benefits and modulation. Therefore improving immune function. Another study found evidence that the way CBD affects the cannabinoid receptor 2 (CB2) lends to the potential of how cannabidiol may help modulate the immune system. The study acknowledges clear evidence that CBD helps immunomodulation during the inflammation process, and that CBD may affect it in four ways. This includes inducing the normal death cycle of cells, decreasing cell creation vs death (increased for tumors), producing more anti- inflammatory agents, and creating more regulatory T cells. Targeting CB2 is cited as a possible revolutionary approach to the treatment of autoimmune and inflammatory diseases. 28.POTENTIAL IN TREATMENT OF HIV-1 INFECTION The boost that CBD may have as anti-inflammatory shows additional possible benefits in boosting immune cell agents against HIV-1. The way CBD works with the CB2 cell provides immune therapeutic possibilities to fight dysfunctional HIV- 1 cells. Using human and animal models, multiple studies found that cannabidiol deactivates important HIV-1 cells, and through CB2 agonists, decreased HIV replication. The same study document noted that THC also has benefits against HIV-1 infection. 29.CBD IS AN EFFECTIVE TREATMENT FOR HEROIN ADDICTION: A new study just released in May of 2019 found intense cravings are the leading cause for drug use, and any substance that reduces this craving may reduce the chance of overdose and relapse. The study took 42 adults with an average heroin use of 13 years and divided them into three groups to take 800mg of CBD, 400mg of CBD, and placebo respectively. Each adult was given the dosage once daily for 3 days consecutively and was studied for the next two weeks. During this time, they were shown pictures of nature along with pictures of heroin-related items such as syringes and then were asked to state their anxiety levels. The study found that the adults who were taking CBD showed a 2-3x reduction in heroin cravings in contrast to the placebo group. The study also showed that the difference between the CBD groups was insignificant. 30.OSTEOARTHRITIS (OA) JOINT & NEUROPATHIC PAIN: Osteoarthritis (OA) is a joint disease that has many facets and effects, such as intermittent inflammation, joint degeneration, and peripheral neuropathy. A new study from 2017 wanted to find if CBD stopped the inflammation that ends up causing Osteoarthritis and neuropathy pain. Additionally, they wanted to analyze CBD’s anti-nociceptive properties (the ability to block the feeling or detection of the injurious or painful stimulus of sensory neurons). Or in less complicated terms, the ability of CBD to stop us from feeling pain or injuries.
  • 7. In order to study this, the doctors induced Osteoarthritis in male rats and then used dosing of CBD to see the effective results. The study found that in end-stage OA, the CBD reduced acute and transient joint inflammation. They also found CBD to be neuroprotective. Meaning, it helps prevent our brains and senses from feeling the discomfort caused by OA. The data from this study indicated that oral administration of CBD blocked OA pain. Concluding that CBD treatment prevented the later development of pain and nerve damage in OA joints and that CBD may be a safe and useful therapy for treating OA joint neuropathic pain. 31. INCREASED EFFECTIVENESS: CBD has been found to have the opposite effect of tolerance, with an increase in effectiveness over time. Therefore, the benefits of CBD may still occur even with a smaller dosage of the same product. Every month or two, you should decrease your dosage of CBD to see if you still receive your desired effects.