This document describes a case study of a 12-year-old male patient presenting with a swelling over his nose and nasal obstruction for 2 months. On examination, the patient was found to have a bluish-red mass obscuring the nasal cavity. Biopsy results showed sheets of plasma cells, lymphocytes, and histiocytes consistent with rhinoscleroma. The patient was started on tetracycline treatment and recanalization of the nasal cavity was planned after 2 weeks. Rhinoscleroma is a rare granulomatous disease caused by Klebsiella rhinoscleromatis infection, characterized by nodular growths in the nasal mucosa.
2. HISTORY
12 yr old male
Of Makkatola,Chattisgadh
c/o
swelling over nose- 2 months
Blocking/obstruction of nose-
2 months
• Increasing gradually
3. HISTORY
Past history - not significant
Family history - not significant
Personal history - baths in lake/boring
well water
4. GENERAL EXAMINATION
GC- mod
Afebrile
P-74/min
BP- 120/80 mmHg
No pallor/clubbing/cyanosis/icterus/edema
Cervical lymphadenopathy
5. Systemic Examination
Respiratory system -NAD
Cardiovascular system - NAD
Gastrointestinal system - NAD
Central Nervous System - NAD
6. LOCAL EXAMINATION
Swelling over nose
extending from supratip to
dorsum, between nasolabial
fold horizontally.
Firm , woody on
consistency
Splaying of nasal bones
with telecanthus
7. LOCAL EXAMINATION
Nose(A/R)
Bluish red mass
obscurring view of
both nasal cavity.
Sensitive to
touch, does not bleed
on touch, firm in
consistency.
9. INVESTIGATIONS
Hematological investigations
-WNL
CT scan
-
small mildly enhancing soft
tissue lesion in anterior part
of nasal cavity arising from
superior wall and blocking
the nares.
10. INVESTIGATIONS
PUNCH BIOPSY
Shows sheets of
plasma cells,
lymphocytes & few
foamy histiocytes
s/o rhinoscleroma
11. TREATMENT
Presently on Tetracyclin 500 mg tds.
Recanalisation is planned after two weeks of medical
treatment.
12. Discussion
Granulomatous disease
Klebsiella rhinoscleromatis, gram negative
encapsulated rod like bacillus
Formation of nodules in mucosal& submucosal layer.
No ulceration or suppuration.
Mode of infection is unknown.
4 stages: catarrhal stage
atrophic stage
nodular/ granulomatous stage
cicatrization
13. DISCUSSION
Presence of an accumulation of plasma cells, lymphocytes &
eosinophils, Miculicz cells & Russel bodies found.
High content of mucopolysacchrides around walls protects
organism
Differential diagnosis: Atrohic rhinitis
Tuberculosis
Lupus vulgaris
Diagnosis: clinical features
Compliment fixation test
Culture
Biopsy
Barylak ,s technique
14. DISCUSSION
Modalities of treatment
-Antibiotics-Streptomycin
-Tetracycline
-Septran
-Chloramphenicol
-Local application – injection of mixture of carbolic
acid, glycerine &acetic acid
-steroid
-Removal of cicatrisation & recanalisation
- Radiotherapy