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Joshua Riley-Graham
    Hurt Brains
  Don’t Think Good
HURT BRAINS DON’T
        THINK GOOD
NEUROLOGICAL DISORDERS AND WHAT THEY TELL US ABOUT
                    OURSELVES!
PHRENOLOGY

•  Wrong, but not stupid!




•  “Le bon Dieu est dans le detail”!
THE NEW PHRENOLOGY

•  Brains = modular!




•  Dedicated bits for particular tasks!
SPECIFIC DAMAGE, SPECIFIC PROBLEMS

•  Can be very specific about where damage is in
   sensorimotor system!
TWO SIDES

•  Split brain patients!




•  Hemispheres are isolated!
TWO SIDES

•  Each hemisphere only sees!
one picture!




•  “You shovel s**t with it”!
VISION

•  Seems like we just get a gestalt…!
VISION

•  Each one of those parts can fail individually and show
   the seams in the system!




•  Fun test of this – adapt just one eye to darkness at a
   time!
AKINETOPSIA

•  Also called “motion blindness”!



•  V5 area of visual cortex is damaged!



•  Movement no longer exists!
BLINDSIGHT

•  Two pathways for vision!

•  Patient has no conscious perception of sight, insists
   they are blind…!

•  …but can guess where objects are and reach for them
   way, way above chance!
VISUAL AGNOSIA

•  Fine visual acuity, no recognition!
VISUAL AGNOSIA

•  Can be for living things, !
non-living things, faces, !
numbers…!




•  Can be ridiculously specific!!
NOT JUST A VISION THING

•  Pure word-deafness!

•  Hearing in general is fine!

•  Reading, writing, speaking fine!

•  No comprehension of speech whatsoever!
HEMISPHERIC NEGLECT

•  Half the world ceases to exist!
HEMISPHERIC NEGLECT

•  Bilateral Extinction!




•  1 + 1 = 1!
ALIEN HAND SYNDROME

•  Dr. Strangelove = not
   entirely fictional!

•  Loss of conscious
   awareness and
   control over a limb, so
   it gets a “mind of its
   own”!
KORSAKOFF’S SYNDROME

•  Thiamine deficiency leads to memory problems leads to
   wild confabulation!




•  “You wouldn’t believe how much that cost to have
   installed”!
CAN’T STOP WON’T STOP

•  Parkinson’s Disease = perseveration!




•  Wisconsin Card Sort Task!




•  PD patients can’t learn new rule!
TOO MUCH OF A GOOD THING

•  Parkinson’s Disease = not enough dopamine being
   produced!



•  Solution? Dopamine-producing drugs!!



•  Problem? Compulsive gambling!!
WHAT IS IT GOOD FOR?
Thank You!
Joshua Riley-Graham

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