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Regulating Phytonutrient Levels in Plants
(Modifying Plant Metabolism
for
Human Health)
Md. Nazrul Islam
Roll: 1280
What are Phytonutrients?
• certain organic chemical components of plants
that are thought to promote human health.
• Also known as:
– functional metabolites,
– phytochemicals, and
– nutraceuticals
Phytonutrient Rich Plants
Phytonutrient Classifiaction
Phytochemicals under research can be classified as follows:
1. carotenoids and
2. polyphenols, which include
– phenolic acids,
– flavonoids, and
– stilbenes/lignans.
• Flavonoids can be further divided into groups, such as
– anthocyanins,
– flavones,
– flavanones,
– isoflavones, and
– Flavanols.
catechin
epicatechin
anthocyanidin
(1) Red foods containing lycopene are involved
in maintaining prostate health;
(2) Yellow-green vegetables containing lutein
and zeaxanthin prevent age-related macular
degeneration;
Health Benefit of Carotenoid & Flavonoids
Health Benefit of Carotenoid & Flavonoids
3) Red-purple foods containing anthocyanins,
are very powerful antioxidants;
4) Tomatoes and tomato based products having
lycopene reduces the risk of chronic diseases
such as cancer and cardiovascular diseases.
Why Improving Phytonutrient Level?
(1) to increase the
efficiency of the
industrial extraction of
these compounds,
(2) to provide an array of
new and attractive
colors to our diet.
Why the improvement of
phytonutrient level is important?
(3) to improve and diversify the diet in populations
of developing countries,
Why Improving Phytonutrient Level?
Strategies to Increase & Diversify the
Phytonutrient Level
(1) transgenic modulation of structural genes
involved in its biosynthesis,
(2) transgenic modulation of genes encoding
transcription factors affecting its metabolic
pathway, &
(3) mutations (spontaneous or induced) in
structural or regulatory genes
Engineering Phytonutrient Synthesis Pathway
Erwinia uredovora
Outstanding Metabolic Engineering
A B
A) Rugular Rice B) Golden Rice
What does Future Hold?
• More clinical in vivo trials are needed.
• There is also a need to formulate appropriate
directives for recommended daily allowance for
each metabolite
• Positioning phytonutrient
consumption behavior at the
pharma level rather than
nutraceuticals.
Summary at a Glance
1. Phytonutrients
2. Health benefits
3. Reasons of improving phytonutrients
4. Ways of improving, &
5. Future perspectives
Recent Advances in Plant Biotechnology, Ara Kirakosyan and Peter B. Kaufman
Reference:
Regulation of Phytonutrient Level in Plant

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Regulation of Phytonutrient Level in Plant

  • 1. Regulating Phytonutrient Levels in Plants (Modifying Plant Metabolism for Human Health) Md. Nazrul Islam Roll: 1280
  • 2. What are Phytonutrients? • certain organic chemical components of plants that are thought to promote human health. • Also known as: – functional metabolites, – phytochemicals, and – nutraceuticals
  • 4. Phytonutrient Classifiaction Phytochemicals under research can be classified as follows: 1. carotenoids and 2. polyphenols, which include – phenolic acids, – flavonoids, and – stilbenes/lignans. • Flavonoids can be further divided into groups, such as – anthocyanins, – flavones, – flavanones, – isoflavones, and – Flavanols. catechin epicatechin anthocyanidin
  • 5. (1) Red foods containing lycopene are involved in maintaining prostate health; (2) Yellow-green vegetables containing lutein and zeaxanthin prevent age-related macular degeneration; Health Benefit of Carotenoid & Flavonoids
  • 6. Health Benefit of Carotenoid & Flavonoids 3) Red-purple foods containing anthocyanins, are very powerful antioxidants; 4) Tomatoes and tomato based products having lycopene reduces the risk of chronic diseases such as cancer and cardiovascular diseases.
  • 7. Why Improving Phytonutrient Level? (1) to increase the efficiency of the industrial extraction of these compounds, (2) to provide an array of new and attractive colors to our diet.
  • 8. Why the improvement of phytonutrient level is important? (3) to improve and diversify the diet in populations of developing countries, Why Improving Phytonutrient Level?
  • 9. Strategies to Increase & Diversify the Phytonutrient Level (1) transgenic modulation of structural genes involved in its biosynthesis, (2) transgenic modulation of genes encoding transcription factors affecting its metabolic pathway, & (3) mutations (spontaneous or induced) in structural or regulatory genes
  • 10. Engineering Phytonutrient Synthesis Pathway Erwinia uredovora
  • 11. Outstanding Metabolic Engineering A B A) Rugular Rice B) Golden Rice
  • 12. What does Future Hold? • More clinical in vivo trials are needed. • There is also a need to formulate appropriate directives for recommended daily allowance for each metabolite • Positioning phytonutrient consumption behavior at the pharma level rather than nutraceuticals.
  • 13. Summary at a Glance 1. Phytonutrients 2. Health benefits 3. Reasons of improving phytonutrients 4. Ways of improving, & 5. Future perspectives
  • 14. Recent Advances in Plant Biotechnology, Ara Kirakosyan and Peter B. Kaufman Reference: