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narendra malhotra jaideep malhotra neharika malhotra www.malhotrahospitals.com [email_address] .
UNDERSTANDING OF  PCOS IN  VARIOUS AGE GROUPS  PCOS WORKSHOPS WERE THE THEME WORKSHOPS OF  FOGSI FOR 2010 AND OF ICOG 2011 ALSO A NATIONAL SURVEY WAS DONE BY  DR JAIDEEP MALHOTRA AND DR BHARTI DHOREPATIL AND DR MANDAKINI
PCOS is not a disease but an ill understood phenomenon defined in various forms over the years
PCOS is defined as a  heterogeneous disorder Presenting with a constellation of different manifestations throught the life of a women “ THIEF OF WOMENHOOD”
[object Object],[object Object]
Fetal programming of PCOS ,[object Object],[object Object],[object Object],[object Object]
Pediatric origin of PCOS ,[object Object],[object Object],[object Object],[object Object]
Phsiology of puberty ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cont….. ,[object Object],[object Object]
CAUSES OF INCREASE IN  ADOLESCENT PCOS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PUBERTAL ENDOCRINE CHANGES RELATED  TO ADOLESCENT PCOS  ,[object Object],[object Object],[object Object]
CLINICAL MANIFESTATIONS SYMPTOMS ASSOCIATED ENDOCRINE MANIFETATIONS POSSIBLE LATE SEQUALE Obesity(38%) Androgens(29%) Diabetes mellitus(29%) Menstrual disturbance(66%) LH(40%) Cardiovascular disease Hyperandrogenism(48%) LH:FSH ratio Hyperinsulinemia Infertility (73% of anovulatory infertility) Free estradiol Low LDL Asymptomatic(20%) Fasting insulin Endometrial carcinoma Prolactin(27%) hypertension Sex hormone binding globulin
PCOS: Goals in Adolescent girls ,[object Object],[object Object],[object Object]
ADOLESCENTS ,[object Object],[object Object],[object Object],[object Object]
Endocrine problems Metabolic problems Infertility Risk of OHSS and multiple pregnancy Pregnancy complications Long term sequel MOST IMP- Importance of life style modification SPECIAL COUNSELING OF A PCOS PATIENT
PROTOCOLS OF MANAGEMENT IN ADOLESCENTS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
STANDARD DIAGNOSTIC ASSESSMENTS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],contd……..
OBJECTIVES  OF  TREATMENT  OF  ADOLESCENT PCOS  ,[object Object],[object Object],[object Object]
PROTOCOLS OF MANAGEMENT  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OBESITY AND PCOS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IMPACT OF OBESITY IN REPRODUCTION Condition  Associated risks Mensturation Ammenorhoea, oligomennorhoea, mennorhagia Infertility Anovualtion, poor response to infertility drugs Miscarriage Increased rate Infertility treatment Increased requirement of oral or injectable ovulation induction agent Decreased success rate of IVF Glucose intolerance Impaired glucose tolerance, type 2 DM Pregnancy Increased PIH, GDM,CS, Downs
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],MENSTRUAL IRREGULARITIES
ORAL CONTRACEPTIVE PILLS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Cyproterone acetate  Ideal for Hirsuit PCOS.
[object Object],[object Object],Ideal for  Obese PCOS DROSPIRENONE
[object Object],[object Object],[object Object]
OTHER DRUGS WHICH CAN BE  USED  IN  ADDITION TO O.C.P.  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
COSMETIC TREATMENT  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Excessive Hair ,[object Object],Laser Waxing Shaving
IMPROVEMENT OF HYPERINSULINEMIA BY    INSULIN SENSITIZERS ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Metformin
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
contd. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OTHER DRUGS WHICH CAN BE  USED  ,[object Object],[object Object],[object Object],[object Object]
RESPONSE TO TREATMENT IS ASSESSED BY ,[object Object],[object Object],[object Object],[object Object],[object Object]
CONCLUSION   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thank you

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Management of adolescent pcosfinal

  • 1. narendra malhotra jaideep malhotra neharika malhotra www.malhotrahospitals.com [email_address] .
  • 2. UNDERSTANDING OF PCOS IN VARIOUS AGE GROUPS PCOS WORKSHOPS WERE THE THEME WORKSHOPS OF FOGSI FOR 2010 AND OF ICOG 2011 ALSO A NATIONAL SURVEY WAS DONE BY DR JAIDEEP MALHOTRA AND DR BHARTI DHOREPATIL AND DR MANDAKINI
  • 3. PCOS is not a disease but an ill understood phenomenon defined in various forms over the years
  • 4. PCOS is defined as a heterogeneous disorder Presenting with a constellation of different manifestations throught the life of a women “ THIEF OF WOMENHOOD”
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  • 12. CLINICAL MANIFESTATIONS SYMPTOMS ASSOCIATED ENDOCRINE MANIFETATIONS POSSIBLE LATE SEQUALE Obesity(38%) Androgens(29%) Diabetes mellitus(29%) Menstrual disturbance(66%) LH(40%) Cardiovascular disease Hyperandrogenism(48%) LH:FSH ratio Hyperinsulinemia Infertility (73% of anovulatory infertility) Free estradiol Low LDL Asymptomatic(20%) Fasting insulin Endometrial carcinoma Prolactin(27%) hypertension Sex hormone binding globulin
  • 13.
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  • 15. Endocrine problems Metabolic problems Infertility Risk of OHSS and multiple pregnancy Pregnancy complications Long term sequel MOST IMP- Importance of life style modification SPECIAL COUNSELING OF A PCOS PATIENT
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  • 20.
  • 21.
  • 22. IMPACT OF OBESITY IN REPRODUCTION Condition Associated risks Mensturation Ammenorhoea, oligomennorhoea, mennorhagia Infertility Anovualtion, poor response to infertility drugs Miscarriage Increased rate Infertility treatment Increased requirement of oral or injectable ovulation induction agent Decreased success rate of IVF Glucose intolerance Impaired glucose tolerance, type 2 DM Pregnancy Increased PIH, GDM,CS, Downs
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