This document discusses fusing coronary CT angiography (CTA) with intravascular ultrasound (IVUS) images to enable quantitative analysis and comparison of plaque characteristics. CTA provides a 3D anatomical view of the coronary arteries but cannot visualize vessel walls, while IVUS has high resolution of vessel walls but only images a single vessel. By mapping and registering CTA and IVUS images, it is possible to validate and compare lumen and vessel wall contours identified on CTA with IVUS as well as extract additional metrics like plaque burden and remodeling index. This fusion could provide more accurate and complete plaque and stenosis analysis than either modality alone.

1. 3D fusion of coronary CT angiography with IVUS images for comparing quantitative analyses A. Broersen Division of Image Processing (LKEB) Department of Radiology Leiden University Medical Center

2. Introduction source: Wikipedia

14. Comparisons - CTA lumen - CTA vessel - IVUS lumen - IVUS vessel

15. Example mapping in MeVisLab