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Asthma Dr Anne Boyter School of Pharmacy Strathclyde Institute of Pharmacy & Biomedical Sciences University of Strathclyde
Introduction
Guideline History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other guidelines ,[object Object],[object Object],[object Object],[object Object]
Asthma definition ,[object Object],ATS
Asthma definition ,[object Object],[object Object],SIGN 101
Diagnosis
Diagnosis ,[object Object],[object Object]
Diagnosis -adults ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
High or low probability ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intermediate probability ,[object Object],[object Object],[object Object],[object Object]
Reference steroid
Reference steroid ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Over age 4   Seretide (Accuhaler) Over age 4   Seretide HFA Over age 4   Accuhaler Over age 4   200mcg MDI (HFA) Fluticasone   Over age 18 Symbicort (regular and as required  dosing)  Over age 6  Symbicort  Over age 6  Novolizer  Over age 6  Easyhaler Over age 2   Metered dose inhaler    400mcg Turbohaler Budesonide No longer available 400mcg Beclometasone dipropionate CFC <5 years 5 – 12 years >12 years Equivalent dose Steroid
Aims of treatment
Aim of management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patient aims of treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]
Stepwise management of asthma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Underlying principles of management ,[object Object],[object Object],[object Object],[object Object]
Stepwise management
 
Adults
Step 1 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Inhaled steroids ,[object Object],[object Object],[object Object],[object Object],[object Object]
Starting dose of inhaled steroid ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other preventer therapies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Add on therapy   ,[object Object],[object Object],[object Object]
Add on therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Step 3:  Add-on therapy Pharmacological management. SIGN 101 May 2008 Inadequate control on low dose inhaled steroids If control still inadequate go to Step 4 Add inhaled long-acting ß 2  agonist (LABA) ,[object Object],[object Object],Benefit from LABA but control still inadequate: Trial of other add-on therapy, e.g. leukotriene receptor antagonist or theophylline Control still inadequate: If control still inadequate go to Step 4 Assess control of asthma ,[object Object],[object Object],No response to LABA: Continue LABA Good response to LABA:
Regular and as required dosing of combination products ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Addition of a fourth drug ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Step 5 ,[object Object],[object Object],[object Object],[object Object]
Steroid sparing medication ,[object Object],[object Object],[object Object],[object Object],[object Object]
Adverse effects
Safety of inhaled steroids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Safety of inhaled steroids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LABA ,[object Object],[object Object],[object Object]
Frequent or continuous oral steroids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Non-pharmacological management
Smoking cessation ,[object Object],[object Object],[object Object]
Non-pharmacological management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Non-pharmacological management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pharmaceutical Care
© Imperial College London Assessment: Royal College of Physicians of London three questions Outcomes and audit. Thorax 2003; 58 (Suppl I): i1-i92 ,[object Object],[object Object],IN THE LAST WEEK / MONTH YES NO “ Have you had difficulty sleeping because of your asthma symptoms (including cough)?” “ Have you had your usual asthma symptoms during the day (cough, wheeze, chest tightness or breathlessness)?” “ Has your asthma interfered with your usual activities (e.g. housework, work, school, etc)?” Date  /  /  /
Asthma Control Test™ (ACT) ,[object Object],[object Object],[object Object],[object Object],[object Object],Score Patient Total Score Copyright 2002, QualityMetric Incorporated. Asthma Control Test Is a Trademark of QualityMetric Incorporated.
 

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Asthma Module 1 session 2 | 24/03/201 | All

Notas do Editor

  1. Reference British Thoracic Society, Scottish Intercollegiate Guidelines Network. British Guideline on the Management of Asthma: A National Clinical Guideline . Revised Edition, 2008.
  2. Reference British Thoracic Society, Scottish Intercollegiate Guidelines Network. British Guideline on the Management of Asthma: A National Clinical Guideline . Revised Edition, 2008.
  3. Reference British Thoracic Society, Scottish Intercollegiate Guidelines Network. British Guideline on the Management of Asthma: A National Clinical Guideline . Revised Edition, 2008.
  4. Reference British Thoracic Society, Scottish Intercollegiate Guidelines Network. British Guideline on the Management of Asthma: A National Clinical Guideline . Revised Edition, 2008.
  5. Reference British Thoracic Society, Scottish Intercollegiate Guidelines Network. British Guideline on the Management of Asthma: A National Clinical Guideline . Revised Edition, 2008.
  6. Reference British Thoracic Society, Scottish Intercollegiate Guidelines Network. British Guideline on the Management of Asthma: A National Clinical Guideline . Revised Edition, 2008.