Electronic Burettes are an innovative product that help perform precise and accurate titrations. They eliminate manual weheel operation by using a motorized piston movement.
2. BURETTES
• One of the most popular and widely used instruments in the
healthcare and life-sciences industry today is the burette.
• A burette is a volumetric measuring glassware which is used
in analytical chemistry for accurate dispensing of variable, and
for measuring the volume of a liquid, especially of one of the
reagents in a titration.
• In a titration of an acid and base solution, the burette can be
filled with acid
3. WHAT IS TITRATION ?
• Titration is a technique where a solution of a known
concentration is used to determine the concentration
of an unknown solution
• Typically, the titrant (the known solution) is added
from a burette to a known quantity of the analyte (the
unknown solution) until the reaction is complete
• Since the volume of the titrant is already known, one
can easily determine the concentration of the analyte
• Often, an indicator is used to signal the end (end-
point) of the titration because of the versatility of the
technique
• Many industries depend on various forms of titration
to develop or analyze key chemical compounds
• Titration is utilized in such fields that affect nearly all
aspects of society
4. USES OF TITRATION
ACID RAIN
• Environmental studies usually involves
precipitation analysis and the response of
precipitation to pollution
• The degree of contamination of rainwater or
snow is actually quantified using titration
• This process tends to be quick and reliable
• As most of the titration processes do not
require expensive or specialized instruments,
they can be easily done in different areas, with
relatively little effort
WASTEWATER ANALYSIS
• The usability of water depends on its chemical
ingredients
• Once we have analyzed wasted water, we can
easily determine the extent of contamination
and the requirements for filtering and cleaning
of the same
• Titration is one of the key steps in wastewater
analysis
• In this case, specialized titration equipment is
used to measure the levels of ammonia in
water in combination with other reactants in
order to quantify other chemicals in the
wastewater
5. USES OF TITRATION
WINE MAKING
• The degree of acidity, also known as the level
of tartness in a wine, greatly affects it‟s flavor
• This quality also plays an important role in
deciding how the wine will respond to ageing
• Therefore, just measuring the acidity of wine
using titration can help improve its production.
• The process is pretty straight forward, uses
minimal equipment and can be easily carried
out by winemakers
• The results of these titration tests suggest the
requirements of additional ingredients to
maintain the quality of the wine
PHARMACOLOGY
• The development of
medicines is one such science that relies on
specific measurements of chemicals
• Thus, titration is one of the most important
parts of the pharmaceutical industry that
ensures quality control in medicines
• Titration and many of its variations are used in
the pharma labs, including various specialized
instruments for pharma titrations that make the
process even more efficient and accurate
6. GLASS BURETTES
• A glass burette is a laboratory equipment used in analytical
chemistry for the dispensing of variable amount of a chemical
solution and measuring that amount at the same time.
• It is a long, graduated glass tube, with a stopcock at its lower end
and a tapered capillary tube at the stopcock's outlet. The flow of
liquid from the tube to the burette tip is controlled by the stopcock
valve.
7. LIMITATIONS OF GLASS BURETTES DURING TITRATION
• First, the burette must be clamped vertically.
• The titrant must be filled vertically. Since this is a manual procedure, potential problems
related to filling till a particular volume depending on the type of the titrating solution, the
safety of the user, might arise.
• Even the process of titration is not easy, as the correct titration speed has to be found,
purely by hit and trial. Too slow, and the titration period is unnecessarily prolonged; too
fast, and the equivalence point is exceeded.
• The valve tightness and security is a common challenge while using a glass burette. If
not secured properly there will be leakage leading to inaccuracy.
• Final reading depends on the accuracy of reading the meniscus manually. Slight neglect
in concentration can lead to inaccuracy.
8. DIGITAL BURETTES – AN ALTERNATIVE
These Digital burettes are directly attached to a bottle filled with the
titrating solution. They offer a number of advantages like:
• While using Digital burettes, hazardous titrating solutions can
be handled without worrying about spillage, thereby ensuring
user safety. The titrant is raised using the knobs on both
sides of digital burettes.
• The display can be reset to zero with a „Clear‟ or „Reset‟
button and the titration can then be started. The standard
solution is dispensed by rotating the hand-wheels with care.
By using the „Pause‟ button, the titration measurement can
be stopped at any time and resumed, as and when needed.
9. BENEFITS OF DIGITAL BURETTES
• An operating error is virtually excluded, since these burettes automatically recognize
the direction of rotation of the hand-wheels, and thus whether the burette is filling or
titrating. Their batteries can supply power for a year in case of typical applications.
• The electronic burette can be used with most common titration solutions (max. 1
mol/l), such as sodium hydroxide, hydrochloric acid or iodine-potassium iodide
solution.
• Certain electronic burette models can also be connected to a PC for direct data
transfer, thus, eliminating potential data transcription errors. In each data transfer, the
burette sends the titrated volume, the serial number of the device, the nominal
volume, the calibration offset, as well as the next calibration date.
11. MICROLIT E-BURETTE VS GENERIC DIGITAL BURETTES
• The Microlit E-Burette has motor controlled piston movements which eliminates all the
problems with Digital Burettes which dispense manually.
• The accuracy due to controlled dispensing is way higher than generic digital burettes.
• No human errors due to automation in most of the work.
12. COMPARISON BETWEEN
GLASS BURETTES VS DIGITAL BURETTES VS MICROLIT E-BURETTE
Glass Burette Digital Burette Electronic Burette
Motorized piston movement No No Yes
On touch refill No No Yes
3 pre- set speeds No No Yes
Digital reading No Yes Yes
13. MICROLIT E-BURETTE
Designed with ergonomics and intuitive
handling in mind, MICROLIT E-BURETTE is
widely used in industries like Pharmaceutical,
Environmental Monitoring, and Food &
Beverages.
It exhibits excellent chemical compatibility
and helps in performing precise titrations
with reliability in practical laboratory
environments.
MICROLIT E-BURETTE is a state-of-the-art
Motor Operated Burette with sophisticated
features and functionality.
Built by our in-house team of product design
engineers, it offers a host of features like:
• Motor Controlled Piston Movement
• A touchscreen-enabled Control Panel
with an intuitive graphical user interface
(GUI)
• 3 Calibrated Pre-Set Speeds to perform
highly accurate titrations
14. 3 PRE-SET SPEEDS FOR DISPENSING
The touchscreen control panel of E-Burette allows three pre-set speeds including drop-wise.
This helps in achieving the endpoint very accurately.
• High-Speed Dispensing: Dispense at 1.517 ml/sec.
• Low-Speed Dispensing: Dispense at 0.491 ml/sec.
• Dropwise Dispensing: Dispense at 0.010 ml/sec.
S. No. Speeds ml/10sec ml/sec
1. Fast
15.17
ml/10sec
1.517
ml/sec
2. Medium
4.91
ml/10sec
0.491
ml/sec
3. Slow
0.13
ml/10sec
0.013
ml/sec
15. MOTOR CONTROLLED PISTON MOVEMENT
• As per ISO 8655-6, Section7.7.2, “Dispensing results are largely affected by the piston
speed in all kind of piston-operated volumetric dispensing devices”
• This is applicable to existing Digital Burettes where dispensing is done „Manually‟ through
a rotating wheel
• The wheel rotation speed is not fixed and varies from user to user
• These abrupt changes in speed lead to inaccurate and imprecise
results
• Motor controlled piston movement of Microlit‟s E-Burette rules
out manual-hand-wheel-operation and inconsistencies arising
due to variations in user speed as it is individually calibrated
at all three pre-set speeds
• This eliminates human error making it „Real Automated Motorized Burette‟
16. RE-DIRECTING REAGENTS WITH RECIRCULATION MODE
Recirculation Mode prevents the loss of reagents during purging by re-directing them into the
mounted bottle and facilitates bubble free dispensing.
EASY DISPENSING WITH FLEXINOZZLE
FlexiNozzle is an adjustable delivery nozzle. It offers a high degree of flexibility in both
the horizontal and vertical directions, facilitating easy dispensing in demanding
laboratory conditions.
QUICK TITRATIONS WITH TFT TOUCHSCREEN
A user-friendly TFT Touchscreen guides quick and accurate titrations and displays
numeric data up to the second decimal. Keep the Stylus pressed against it to perform
dispensing and lift it to stop at once.
17. ENHANCED FUNCTIONALITY WITH A ROBUST CONTROL PANEL
The instrument comes with a powerful Control Panel. Use it to perform
functions like automatically re-fill without changing the reading, perform a zero
reset (via Tare),switch the instrument off, etc.
TOUGHENED MATERIALS
The external components of the instrument are made up of specially
selected glass filled polypropylene. This ensures high mechanical
strength and high dimensional accuracy of components.
18. ACCURACY
Model No. Capacity Increment
Accuracy CV
±% ±mL ±% ±mL
TI-10 10 mL 0.005 mL 0.2 0.02 0.07 0.0070
TI-25 25 mL 0.01 mL 0.2 0.05 0.07 0.0175
TI-50 50 mL 0.01 mL 0.2 0.10 0.07 0.0350
19. OTHER FEATURES OF MICROLIT E-BURETTE
• Computer connectivity is available through a micro-USB cable for transferring and
recording data
• Conforms to ISO 8655 standards & GLP compliant
• Each instrument is individually calibrated in Microlit‟s NABL accredited laboratory (as per
ISO 17025) and supplied with a calibration certificate
• Five adapters: 28mm, 32mm, 36mm, 40mm, and 45mm are provided along with the
instrument to fit almost all the laboratory reagent bottles
• Easy power-off from the touch control panel
• A telescopic filling tube is provided which can be adjusted in length
• The delivery nozzle can be adjusted both horizontally & vertically for different laboratory
conditions
20. OTHER FEATURES OF MICROLIT E-BURETTE
• Rechargeable, long-life, replaceable batteries are provided in the control panel
• E-Burette comes with a hand-held stylus which assists in perfect and easy touch
operation of the control panel
• Amber colored window is provided as an accessory for those chemicals/reagents that are
sensitive to light
