1. Trust your Patient-Driven eData with PHT
eDiaries &
Connected
Health
Anne Pelz,
Manager, Product Management,
PHT
Prepared for MassTLC Connected
Health Seminar 07 May 2013

2. 22
eDiary Technology in Clinical Trials

3. 33
Early Days of eDiaries in Clinical Trials

4. 44
ePRO-Generated Email Alerts Increased
Symptom Control in Oncology
2011, J Clin Oncol., 29:994
Study Design
•Randomized trial (n=100) with lung cancer and metastasis using automated phone system
•Patients had received a cancer-related thoracotomy (highly symptomatic first few post-op wks)
•Email alerts were sent to clinical team if specific symptoms crossed a threshold
•2 groups (Control group – no email alerts) and intervention group (email alerts) (4 wk trial)
Results
•11% decrease in severe symptoms in the email alerts group, with high overall system
satisfaction
•84% of clinicians responded to the email alerts within 24 hours
Conclusions
•Clinicians integrated alerts into clinical workflows, and doing so improved symptom control

5. 55
ePRO-Generated Email Alerts Increased
Symptom Control in Oncology
2011, J Clin Oncol., 29:994
Pain 56
28
Distress
Shortness
of Breath
Disturbed Sleep
Constipation

6. 66
Higher Compliance with More Clinician Review
74% 76%
81%
91%
50%
60%
70%
80%
90%
100%
Daily Diary Twice Daily Diary
DiariesCompleted(%ofexpected
diaries)
Limited Report
Use
Significant Report
Usage

7. 77
Glucose readings logbook