Pharmacology for dentistry

1. Applied Pharma
For Dentistry
By: Ahmed Fathy
Edited by: MO'men G. AbouDaif

2. Ahmed Fathy Ibraheem
Faculty of dentistry
October 6 university
‫و‬‫أ‬ , ‫العلمي‬ ‫ابحملتوي‬ ‫مقصود‬ ‫غري‬ ‫خطأ‬ ‫و‬‫أ‬ ‫تعليق‬ ‫ي‬‫أ‬ ‫وجود‬ ‫حاةل‬ ‫يف‬ ‫معي‬ ‫اصل‬‫و‬‫الت‬ ‫رجو‬‫أ‬
‫يد‬‫ر‬‫ت‬ ‫كنت‬ ‫ذا‬‫ا‬‫ما‬ ‫معلومة‬ ‫عن‬ ‫تفسار‬‫س‬‫ال‬
Mobile : 01224784190
Gmail : dentistahmedfathy314@gmail.com
Facebook : facebook.com/Dentist.Ahmed.Fathy

3. Content
1) How to write a prescription
2) Important abbreviations
3) ‫االطفال‬ ‫في‬ ‫الجرعة‬ ‫حساب‬
4) Food and drug administration
5) Antibiotics
6) Analgesics
7) Anti-fungal drug
8) Anti-viral drug
9) Muscle relaxant
10) Vitamins
11) Calciums
12) Mouth wash
13) Anti-edematous drug
14) Other drugs
15) Systemic drugs
16) How to deal with medical comprimised patient
17) Antibiotic prophylaxis for dental patient at risk for infection .
18) References ( ‫المعلومات‬ ‫مصادر‬ )
***************************************

4. 1) Name of drug ………. ( Augmentin _ Cataflam ) .
2) Type of presentation ………. ( Capsule _ Ampoule _ Syrup ) .
3) Cont. of drug ………. (75 mg _ 1 g _ 500 mg ) .
4) Amount of drug ………. (3 amp _ 2 vial _ ‫)شريط‬ .
5) Instruction for the patient , this should be written in Arabic ,
including amount of drug to be taken , frequency , dose , route
of administration .
6) During writing prescription :
Don’t speak with patient .
Avoid drug interaction ( ‫جتنب‬‫ية‬‫و‬‫د‬‫ال‬‫مهنم‬ ‫احد‬‫و‬ ‫ممكن‬ ‫ليل‬‫ا‬‫ثر‬‫ؤ‬‫ي‬‫عيل‬
‫ا‬ ‫مفعول‬‫لث‬‫هنايئ‬ ‫معهل‬ ‫يلغي‬ ‫و‬‫أ‬ ‫اين‬)
Avoid rewriting prescription .
R/
cataflam 75mg amp (3)
‫كل‬ ‫عضل‬ ‫حقنة‬12‫ساعة‬
How to write a prescription
Name of
drug
Cont. of drug Type of
presentation
on
Amount of
drug
including (dose ,ArabicInstruction for patient in
frequency ,route of administration )

5. Presentation
 Tab= tablet (‫أقراص‬)
 Cap= capsule (‫كابسول‬)
 Amp= ampoule (‫أمبول‬)
 Susp= suspension
(‫يف‬ ‫ابلاكمل‬ ‫مذابة‬ ‫بتكون‬ ‫مش‬ ‫الفعاةل‬ ‫املادة‬ ‫لكن‬ ‫اب‬‫رش‬‫ال‬ ‫زي‬solvent )‫يرتج‬ ‫يحتاج‬‫ب‬ ‫وده‬ , )
‫تخدام‬‫الاس‬ ‫قبل‬ ‫يس‬‫و‬‫ك‬)
 Supp= suppository ) ‫لبوس‬ )
 Vial= vial ‫بودر‬ ‫عن‬ ‫عبارة‬ ‫بتكون‬ ‫حقن‬‫موضعي‬ ‫خمدر‬ ‫او‬ ‫مقطر‬ ‫ماء‬ ‫ومعها‬) )
 Syrup= syrup )‫)شراب‬
 Eff = effervescent ( ‫فوار‬ )
Important abbreviation

6. Units
Kg = kilograms
g = gram …..( Hibiotic 1g)
mg = milligram ….(cataflam 75mg )
 ml = milliliter …. (Brufen 100mg/5ml)
************************
Administration route
IM = intramuscular () ‫عضل‬
IV = intravenous ) ‫وريد‬ (
 SC = subcutaneous ) ‫الجلد‬‫تحت‬ (

7. ‫ال‬‫األطف‬‫في‬ ‫الجرعة‬‫حساب‬
‫دواء‬ ‫مثال‬‫جرعت‬‫ه‬30 mg/kg/d
1)‫الطفل‬ ‫وزن‬ ‫المثال‬ ‫سبيل‬ ‫علي‬10‫الطفل‬ ‫وزن‬ ‫هتضرب‬ ‫يعني‬ ‫كجم‬x‫كمية‬
‫يعني‬ ‫الواحد‬ ‫للكيلو‬ ‫الدواء‬30 x 10 = 300 mg ). )
( ‫مثال‬ ‫الدواء‬ ‫تركيز‬ ‫طيب‬125 mg/5ml‫يعني‬ )1= ‫مل‬25. ‫مجم‬
=
300
25
12,‫يوم‬ ‫كل‬ ‫محتاج‬ ‫الطفل‬ ‫يبقي‬12‫علي‬ ‫تقسم‬ , ‫مل‬3‫يبقي‬ , ‫يوميا‬ ‫مرات‬
4‫صغيرة‬ ‫ملعقة‬ ‫يعني‬ ( ‫مرة‬ ‫كل‬ ‫مل‬3) ‫يوميا‬ ‫مرات‬.
2): ‫أخري‬ ‫طريقة‬
‫الطفل‬ ‫وزن‬10‫كجم‬30 x 10 = 300 mg
‫الدواء‬ ‫تركيز‬ ‫إن‬ ‫وبما‬125 mg/5ml
‫يعني‬5ml125 mg
‫؟؟‬300 mg
) ‫الكمية‬ ( ‫المقص‬ ‫بطريقة‬
300𝑥25
125
=12‫مل‬
‫سبق‬ ‫كما‬ ‫وتقسم‬3( ‫يوميا‬ ‫مرات‬4. ) ‫مرة‬ ‫كل‬ ‫مل‬
: ‫ملحوظة‬
( ‫الصغيرة‬ ‫المعلقة‬tea spoon= )4‫مل‬
( ‫الكبيرة‬ ‫المعلقة‬soup spoon= )8‫مل‬

8. ( ‫امسها‬ ‫يكية‬‫ر‬‫م‬‫أ‬ ‫منظمة‬ ‫يف‬U.S FDA( ‫يكية‬‫ر‬‫م‬‫أ‬ ‫ملنظمة‬ ‫لمس‬ ‫اختصار‬ ‫دي‬ )Food
and drug administration‫قسمت‬ ‫دي‬ ‫املنظمة‬ , ‫يكية‬‫ر‬‫م‬‫ال‬ ‫اء‬‫و‬‫ادل‬‫و‬ ‫الغذاء‬ ‫منظمة‬ ‫ومعناها‬ )
‫يل‬‫ا‬ ‫امل‬‫و‬‫احل‬ ‫عيل‬ ‫وخطورهتا‬ ‫ية‬‫و‬‫د‬‫ال‬5 Category:
Studies in women fail to demonstrate risk in fetus .Category (A)
(generally acceptable )
Result of animal reproduction studies have not
demonstrate fetal risk but there is no controlled
studies in pregnant women .
‫منا‬‫ا‬ , ‫بعد‬ ‫مشلكة‬ ‫يظهر‬ ‫ومل‬ ‫ان‬‫و‬‫احلي‬ ‫عيل‬ ‫اسات‬‫ر‬‫د‬ ‫فيه‬ ‫يعين‬
. ‫نسان‬‫ال‬ ‫عيل‬ ‫مؤكدة‬ ‫اسات‬‫ر‬‫د‬ ‫يوجد‬ ‫ل‬
Category (B)
(may be acceptable )
Result of studies on animal have revealed adverse
effect (teratogenic ) .
‫هناك‬ ‫ن‬‫أ‬ ‫توحض‬ ‫ان‬‫و‬‫احلي‬ ‫عيل‬ ‫اسات‬‫ر‬‫د‬ ‫يف‬Risk‫عيل‬
. ‫اء‬‫و‬‫ادل‬ ‫تخدام‬‫اس‬ ‫من‬ ‫اجلنني‬
Category (C)
(use with caution)
‫يف‬ ‫فقط‬ ‫تخدم‬‫تس‬ , ‫اجلنني‬ ‫عيل‬ ‫ية‬‫و‬‫د‬‫ال‬ ‫هذه‬ ‫خطورة‬ ‫تؤكد‬ ‫اسات‬‫ر‬‫د‬ ‫يف‬
‫حاةل‬life threating. ‫من‬‫أ‬ ‫اثين‬ ‫بديل‬ ‫يوجد‬ ‫ول‬
Category (D)
Don’t use it .Category (x)
Food and Drug Administration

9. Clinical consideration regarding medication use in
patient who are pregnant :
1) Use medication only if expected benefits greater than potential risk
‫مثل‬ , ‫اجلنني‬ ‫عيل‬ ‫ية‬‫و‬‫د‬‫ال‬ ‫خطر‬ ‫من‬ ‫كرث‬‫أ‬ ‫م‬‫لل‬ ‫بة‬‫ابلنس‬ ‫فادة‬‫ال‬ ‫يكون‬ ‫ملا‬ ‫ية‬‫و‬‫د‬‫ال‬ ‫تخدم‬‫اس‬
‫ية‬‫و‬‫د‬‫أ‬anti convulsant )‫لكها‬ )C/D‫ن‬‫ل‬ ‫تخدم‬‫تس‬ ‫ذكل‬ ‫ومع‬Convulsion. ‫خطر‬‫أ‬
2) Avoid prescribing medication during patient first trimester .
3) Prescribe the minimum dose required to obtain describe effect .
. ‫فيه‬ ‫املرغوب‬ ‫ثري‬‫التأ‬ ‫عيل‬ ‫حتصل‬ ‫ليك‬ ‫ممكنة‬ ‫جرعة‬ ‫قل‬‫أ‬ ‫تخدم‬‫اس‬
***************************************
Clinical consideration regarding medication use in
patient who are breast feeding :
1) Advise patient to minimize the breast child exposure to drug the
mother is receiving .
‫قبل‬ ‫اتين‬ ‫الطفل‬ ‫ومرتضعش‬ , ‫مبارشة‬ ‫الرضاعة‬ ‫بعد‬ ‫يفضل‬ ‫يبقي‬ , ‫العالج‬ ‫هتاخد‬ ‫م‬‫ال‬ ‫لو‬
‫ساعة‬‫م‬ ‫ساعتني‬ ‫و‬‫أ‬) ‫للطفل‬ ‫من‬‫أ‬ ( . ‫العالج‬ ‫تناول‬ ‫ن‬
2)‫عيل‬ ‫اء‬‫و‬‫ادل‬ ‫ثري‬‫بتأ‬ ‫م‬‫ال‬ ‫تعرف‬ ‫لزم‬infant‫ي‬‫أ‬ ‫ظهور‬ ‫حصل‬ ‫لو‬‫و‬effect. ‫مبارشة‬ ‫اء‬‫و‬‫ادل‬ ‫توقف‬
‫مثل‬ (clindamycin‫للطفل‬ ‫يعمل‬ ‫ممكن‬pseudo. Colitis)
3)‫عيل‬ ‫اء‬‫و‬‫ادل‬ ‫ثري‬‫تأ‬ ‫ترشح‬ ‫لزم‬milk‫لل‬ ‫د‬ ‫ترشح‬‫و‬ _ ‫عليه‬ ‫ثر‬‫هيأ‬ ‫لو‬ _patient. ‫بوضوح‬
‫(مثل‬metronidazole. ) ‫للنب‬‫ا‬ ‫طعم‬ ‫بيغري‬

10.  Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
 Allergy
Adverse effect
 Gastro intestinal
disturbance
 Reduce dose in patient with
renal impairement and liver
dysfunction.
Precaution
No contra-indication
(category B )
Pregnancy
No contra-indicationBreast-feeding
Penicillin
 Dental infection , sinusitis , dental cellulitis .
 Salivary gland infection .
Use

11.  Trade names :
Ampicillin 500 mg 12 cap 10 L.E
Ampicllin 500 mg vial 5 L.E
Epicocillin 250 mg 12 cap 6.5 L.E
‫ملحوظة‬:
‫خذ‬‫ببيأ‬orally‫لك‬‫ال‬ ‫مع‬ ‫لو‬ ‫خاصة‬ ‫يس‬‫و‬‫ك‬ ‫ميتص‬‫ب‬ ‫مش‬ ‫لكنه‬ ‫املعدة‬ ‫محوضة‬ ‫بيقاوم‬ ‫نه‬‫ل‬‫خذ‬‫يأ‬ ‫ذلكل‬ (
. ) ‫فاضية‬ ‫معدة‬ ‫عيل‬
‫عيل‬ ‫ثر‬‫فبيأ‬ ‫امتصاص‬ ‫بيحصلها‬ ‫مش‬ ‫منه‬ ‫كبرية‬ ‫مكية‬ ‫ن‬‫ل‬bacterial flora‫مشهور‬ ( ‫سهال‬‫ا‬ ‫فيعمل‬
) ‫كده‬ ‫عنه‬.
Ampicillin
Dose
( ‫قرص‬500 mg‫كل‬ )8, ‫ساعات‬‫فاضية‬ ‫معده‬ ‫علي‬.
( ‫األطفال‬ ‫في‬ ‫الجرعة‬50 – 100 mg /kg/d. )

12.  Trade names :
Amoxil 500 mg 12 cap 9 L.E
Amoxil 125 mg /5ml syrup 8 L.E
Emoxil 500 mg 16 cap 8 L.E
Emoxil 500 mg Vial 6 L.E
Emoxil 125 mg /5ml Syrup 8 L.E
250 mg /5ml 8 L.E
Ibiamox 500 mg 12 cap 10 E.L
Ibiamox 200 mg/5ml Syrup 7.5 L.E
400 mg/5ml 10 L.E
Biamox 250 mg 12 cap 7 L.E
500 mg 11 L.E
Biamox 125 mg/5ml Syrup 6 L.E
250 mg/5ml 9 L.E
Ospamox 1 g 12 tab 15.5 L.E
Amoxicillin
Dose
 Adult :
( ‫كبسولة‬500 – 250 mg‫كل‬ )8‫حسب‬ ( . ‫ساعات‬
) ‫الحالة‬
( ‫قرص‬1 g‫كل‬ )12. ‫ساعة‬
 Child : ( 25 – 50 mg /kg/d )

13. : ‫ملحوظة‬
 Dose of amoxicillin should be doubled in severe infection in adult
and child .
‫الالك‬ ‫مع‬ ‫افضل‬ ‫بيكون‬ ‫متصاصه‬‫ا‬ ‫ن‬‫ل‬ ‫مبارشة‬ ‫لك‬‫ال‬ ‫بعد‬ ‫خذ‬‫يأ‬.
 Trade names :
Flumox 1 g 15 cap 43 L.E
Flumox 500 mg 16 cap 32 L.E
250 mg 20 tab 14L.E
Flumox 1 g Vial
Flumox 250mg/5ml Syrup 23.5 L.E
Floxamo 1 g 16 tab 36 L.E
Amofluxin 500 mg 12 cap 10 L.E
Amoxicillin + flucloxacillin
Dose
 Adult ( ≥ 18 yrs ) :
( 500 mg cap )‫كبسولة‬3‫يوميا‬ ‫مرات‬
( 1 g cap )‫كل‬ ‫كبسولة‬12‫ساعة‬
( 1g vial )‫كل‬ ‫حقنة‬12‫ساعة‬
 Child : ( 25 – 100 mg/kg/d ) . ‫علي‬ ‫الجرعة‬ ‫تقسم‬3‫يوميا‬ ‫مرات‬

14.  Trade names:
90 L.E14 tab1 gAugmentin
52 L.E10 tab652 mgAugmentin
36 L.E375 mg
55 L.ESyrup457mg/5mlAugmentin
48 L.E312mg/5ml
75 L.E16 tab1 gHibiotic
71 L.E16 tab652 mgHibiotic
57 L.E20 tab375 mg
41 L.ESyrup460mg/5mlHibiotic
312mg/5ml
75 L.E10 tab1 gMegamox
60 L.E14 tab625 mg
52.5 L.ESyrup457mg/5mlMegamox
76 L.E12 tab1 gCuram
49 L.E625 mg
38 L.ESyrup457mg/5mlCuram
52 L.E312mg/5ml
E-moxclav 457mg/5ml syrup 36 L.E
E-moxclav 156mg/5ml 19 L.E
Amoxicillin + clavulanic acid

15. : ‫ملحوظة‬
Clavulanic‫مادة‬hepatotoxic‫يف‬ ‫ية‬‫و‬‫الاد‬ ‫هذه‬ ‫تفضل‬ ‫ل‬ ‫ذلكل‬‫الكبد‬ ‫مريض‬.
**************************************************
 Trade names :
unictam 1.5 g Vial 19 L.E
unictam 750 mg Vial 12 L.E
375 mg 7.5 L.E
unictam 375 mg 12 tab 30 L.E
unictam 250mg/5ml Syrup 38 L.E
Sulbin 1.5 g Vial 20 L.E
Sulbin 750 mg Vial 14 L.E
Sulbin 375 mg Vial 10 L.E
Dose
 Adult:
( 375 mg tab )‫قرص‬3‫يوميا‬ ‫مرات‬
( 625 mg tab )‫كل‬ ‫قرص‬12‫ساعة‬
( 1 g tab )‫كل‬ ‫قرص‬12‫الشديدة‬ ‫العدوي‬ ‫حالة‬ ‫في‬ ‫وذلك‬ , ‫ساعة‬
 Child ( ≥ 6 yrs ) :
( 457 mg _ 460 mg syrup )3‫م‬‫يوميا‬ ‫رات‬
 Child ( 3 – 6 yrs ) : ( 25 – 100 mg/kg/d )
Ampicillin + sulbctam

16. Unasyn 1.5 g Vial 32 L.E
Unasyn 750 mg Vial 22 L.E
375 mg 16 L.E
Unasyn 375 mg Tab 30 L.E
Unasyn 250 mg Syrup 49.5 L.E
Dosage
 Adult :
( 750 mg vial )‫كل‬ ‫حقنة‬12‫ساعة‬
( 1.5 g vial )‫كل‬ ‫حقنة‬12‫الشديدة‬ ‫العدوي‬ ‫حالة‬ ‫في‬ ‫وذلك‬ , ‫ساعة‬
‫مثل‬cellulitis
375 mg tab )‫كل‬ ‫قرص‬ )8‫ساعات‬.
 Child: (150 mg/kg/d )
‫أقل‬ ‫الطفل‬ ‫وزن‬ ‫لو‬10‫كل‬ ‫حقنة‬ ....... ‫كجم‬12( ‫ساعة‬( 375 mg
‫الطفل‬ ‫وزن‬ ‫لو‬10–20‫كل‬ ‫حقنة‬ ..... ‫كجم‬12( ‫ساعة‬750 mg)
3( ‫يوميا‬ ‫مرات‬250 mg syrup).
‫ملحوظة‬( ‫الحقن‬ :1.5 g‫في‬ ‫تحل‬ )10‫عضل‬ , ‫أفضل‬ ‫وريد‬ ‫وتأخذ‬ ‫سم‬
. ‫جدا‬ ‫مؤلمة‬

17. 
 Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
Adverse effect Allergy
Precautions  Reduce dose in patient with renal
disease .
Pregnancy No contra indication .
category ( B )
Breast –feeding No contra indication .
Drug inter-action  Warfarin ( increase effect)
 Trade names:
Curisafe 1 g 8 cap 18 L.E
500 mg 15 L.E
Cephalosporins
Use
 Broad spectrum antibiotic .
 Odontogentic infection .
 Use as a prophylaxis .
Cephadroxil
1st
generation

18. Curisafe 250mg/5ml Syrup 15 L.E
125mg/5ml 12 L.E
Duricef 125mg/5ml syrup 12 L.E
 Trade names :
Ceftriaxone 1 g Vial 52 L.E
Ceftriaxone 250 mg Vial 11 L.E
500 mg 32 L.E
Cefaxone 1 g Vial 36 L.E
‫معامه‬ ‫بيكون‬ ‫عضل‬ ‫بتتاخد‬ ‫ليل‬‫ا‬ ‫احلقن‬‫موضوعي‬ ‫خمدر‬‫معاها‬ ‫بيكن‬ ‫الوريد‬ ‫ما‬‫أ‬ ,‫مقطر‬ ‫ماء‬,
. ‫وريد‬ ‫ول‬ ‫عضل‬ ‫هياخد‬ ‫يض‬‫ر‬‫امل‬ ‫حتدد‬ ‫لزم‬ ‫كدة‬ ‫علشان‬
Dosage
 Adult:
( ‫يوميا‬ ‫مرتين‬ ‫قرص‬500 mg)
‫كل‬ ‫قرص‬12( ‫ساعة‬1 g. ‫الشديدة‬ ‫العدوي‬ ‫حالة‬ ‫في‬ )
 Child : ( 30 mg/kg/d ) .
Ceftriaxone
3rd
generation

19. ***********************************************************
First choice in case of penicillin allergy .
Concentrated in bone and teeth .
 Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
Pseudomembranous colitis .
( stop therapy )
Side effect
 Reduce dose in patient with liver
impairement .
Precautions
 Use Only in 2nd
and 3rd
Pregnancy
Dose
 Adult :
‫كل‬ ‫حقنة‬12( ‫ساعة‬1 g, )Max. dose ( 4 g/d )
 Child :
( 50 – 100 mg/kg/d ) , Max. dose ( 2 g/d )
Notes
use
 Odontogenic infection . ( first choice )
 Gingivitis .
Clindamycin

20. trimester .
( category B )
Use with caution if there is no
therapeutic alternative . ( risk of
pseudo. Colitis )
Breast-feeding
 Not use with patient receiving
vitamin K therapy .
Drug interaction
 Trade names :
Dalacin_c 300 mg 10 cap 52.5 L.E
150 mg 16 cap 29 L.E
Dalacin_c 600 mg vial 46 L.E
300 mg 16 L.E
Clindam 150 mg 16 cap 28 L.E
Clindam 300 mg 16 cap 38 L.E
Dosage
 Adult ( ≥ 13 yrs ) :
‫كبسولة‬3( ‫يوميا‬ ‫مرات‬300 mg cap)
‫كل‬ ‫حقنة‬8( ‫ساعات‬300 mg vial)
‫كل‬ ‫حقنة‬12( ‫ساعة‬600 mg vial‫الحاالت‬ ‫في‬ )severe.
 Child ( ≥ 4 yrs ) :
‫كبسولة‬3( ‫يوميا‬ ‫مرات‬150 mg cap)

21.  Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
Side effect Allergy .
Precautions  Don’t use with patient taking
alcohol .
Pregnancy No contra-indication .
( category B )
Breast-feeding  Contra-indicated .
Drug inter action  Warfarin .
 Trade names :
Flagyl 500 mg 20 tab 12 L.E
250 mg 11 L.E
Use
 Bacterial infection . ( anaerobic bacteria )
 dental abcess .
 acute peri-coronitis .
 acute ulcerative gingivitis .
Metronidazole

22. Flagyl 125 mg/5ml Syrup 10 L.E
Amrizole 500 mg 20 tab 10 L.E
250 mg 7 L.E
Amrizole 200 mg syrup 10 L.E
 N.B:
Advise patient to avoid alcohol metronidazole has
disulfiram_like reaction with alcohol , this caused by
metronidazole inhibiting the metabolism of alcohol , lead to build
up of aldehydes which produce nausea , vomiting .
Contra-indicated in breast-feeding due to it excerted in milk so
unpleasant taste for milk and risk of GIT disturbance in infant .
Dosage
 Adult ( ≥ 17 yrs ) :
‫قرص‬3( ‫يوميا‬ ‫مرات‬500 mg tab)
 Child ( ≥ 10 yrs ) :
‫قرص‬3( ‫يوميا‬ ‫مرات‬250 mg tab)
 Child ( ≥ 3 yrs ) : ( 30 mg/kg/d )
 Increase dose with patient taking corticosteroid and
barbiturates . (this drug increase metronidazole loss )

23.  Drug used during pregnancy and breast-feeding :
Drug During pregnancy During breast-
feeding
Penicillin Yes ( B ) Yes
Cephalosporin Yes ( B ) yes
Clindamycin Yes ( B ) With caution
Metronidazole Yes ( B ) Avoid
‫المرضي‬ ‫لبعض‬ ‫للجرعة‬ ‫تعديل‬ ‫هتحتاج‬ ‫اللي‬ ‫األدوية‬:
1)‫جرعة‬ ‫هتقلل‬penicillin,cephalosporins. ‫الكلي‬ ‫مرضي‬ ‫في‬
2)‫جرعة‬ ‫هتقلل‬penicillin,clindamycin. ‫الكبد‬ ‫مرضي‬ ‫في‬
3)‫أدوية‬clavulanicamoxicillin +‫لمرضي‬ ‫تكتب‬ ‫ال‬‫الكبد‬‫ألن‬
clavulanic acid‫مادة‬hepatotoxic.
Important
points

24. Therapeutic effect come from the inhibiting of the cyclo-
oxygenase enzyme .
3 important effect :
1) Analegesic 2) anti inflammatory 3) anti pyretic
) ‫ارة‬‫ر‬‫للح‬ ‫(خافض‬‫لاللهتاب‬ ‫(مضاد‬))‫(مسكن‬
 Types :
 Non selective cox inhibitor
1) Salicylates
 Acetylsalicylic ( Aspirin )R
2) Propionic acid derivatives
 Ibuprofen ( Brufen )R
ketoprofen ( ketofan )R
3) Acetic acid derivatives
 Ketorolac ( ketolac )R
4) Declofenac sodium
( Voltaren )R
( Declophen )R
5) Declophenac potassium
( cataflam )R
( flector )R
( dolphin k )R
1)NSAID

25.  Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
 Trade names :
Aspirin protect 100 mg 30 tab 21 L.E
Adverse effect Hypersensitivity reaction
(bronchospasm )
GIT : ulcer
Precautions  Don’t administer to this
patient :
 Allergic to aspirin
 Peptic ulcer
 Coagulation disorder
 Severe renal disease
Pregnancy Contra-indicated
Category ( C )
Breast-feeding Used with caution
Drug inter-action  Warfarin
 Digoxin
Aspirin
Dosage
 Adult :
‫قرص‬3( ‫يوميا‬ ‫مرات‬100 mg tab)
 Child : not used with children ≤ 6 years .
( reye syndrome : fatal hepatic injury ,
encephalopathy in children ) .

26.  Trade names :
Ketolgin 200 mg 10 cap 10 L.E
50 mg 30 tab 12 L.E
Ketolgin 100 mg Amp
Ketofan 50 mg 20 tab 10.5 L.E
25 mg 7.5 L.E
Ketofan SR 200 mg 14 tab 14 L.E
Ketofan 100 mg Amp 5 L.E
Ketofan 75 mg Cap
18 L.E20 cap75 mgKetoprek
**********************************************
 Trade names :
Rapifen 200 mg 10 cap 5.5 L.E
‫كبسولة‬‫كل‬12‫ساعة‬(capmg200).
Ketoprofen
Dosage
 Adult :
3/4( ‫يوميا‬ ‫مرات‬25 – 50 mg. )
‫كل‬12( ‫ساعة‬75 – 200 mg. )
( ‫يوميا‬ ‫عضل‬ ‫حقنة‬100 mg amp).
Ibrufen
‫الجرعة‬

27. Brufen 600 mg 30 tab 31.5 L.E
Brufen 400 mg 30 tab 29 L.E
200 mg 19 L.E
Brufen 100mg/5ml syrup 12 L.E
***************************
18 L.E20 tab10 mgKetolac
18 L.E5 amp30 mgKetolac
7.5 L.E3 amp30 mgAdolor
Dosage
 Adult :
‫كل‬8( ‫ساعات‬400 mg tab)‫األ‬ ‫بعد‬‫كل‬.
‫كل‬12( ‫ساعة‬600 mg tab)‫األكل‬ ‫بعد‬.
 Child ( 7-9 yrs ) :
3( ‫مرات‬200 mg tab)‫األكل‬ ‫بعد‬.
 Child ( 3- 6 yrs ) :
3( ‫يوميا‬ ‫مرات‬syrup)
40 mg/kg/d )-( 30
Ketolorac

28. 1)‫مريض‬ ‫في‬ ‫فقط‬ ‫الجرعة‬ ‫نصف‬ ‫تأخذ‬‫الكلي‬‫من‬ ‫أكبر‬ ‫او‬65‫سنة‬.
2)‫من‬ ‫أكثر‬ ‫تأخذ‬ ‫ال‬ ‫الحقن‬‫يومين‬‫واألقراص‬ ,5‫أيام‬.
*****************************************
 Trade names :
Voltaren 50 mg 20 tab 21.5 L.E
Voltaren 75 mg Amp 7.5 L.E
Declophen 50 mg 20 tab 11 L.E
Declophen 75 mg Amp 7.5 L.E
Dosage
 Adult :
‫كل‬ ‫حقنة‬12( ‫ساعة‬amp. )
3( ‫يوميا‬ ‫مرات‬tab. )
‫مهم‬
Declophenac sodium
Dosage
 Adult :
‫كل‬8( ‫ساعات‬50 mg tab. )
‫كل‬12( ‫ساعة‬75 mg amp. )

29.  Trade names :
Cataflam 25 mg 20 tab 33 L.E
50 mg 21 L.E
Cataflam 75 mg Amp 8.5 L.E
Dolphin-K 75 mg 10 cap 13 L.E
50 mg 20 tab 18 L.E
Dolphin-K 75 mg Amp 4 L.E
Declophenac not recommended for patient with heart disease .
Not recommended for children less than 3 years .
Declophenac potassium
Dosage
 Adult:
‫كل‬ ‫قرص‬8( ‫ساعات‬50 mg tab. )
‫كل‬ ‫حقنة‬12( ‫ساعة‬amp)
‫كل‬ ‫كبسولة‬12( ‫ساعة‬75 mg cap.)
( ‫األطفال‬ ‫في‬ ‫الحقن‬ ‫جرعة‬1cm /20kg).cataflam 75mg amp) …)
important

30. (‫الكلي‬‫لمرضي‬ ‫مسكن‬ ‫أفضل‬)
 Trade names :
17 L.E20 tab200 mgRudac
14 L.E20 tab150 mgRudac
15.5 L.E20 tab150 mghidac
( ‫ألنه‬ ‫الكلي‬ ‫مرضي‬ ‫مع‬ ‫يفضل‬less renal toxicity‫أمالح‬ ‫عنده‬ ‫اللي‬ ‫في‬ ‫يفضل‬ ‫ال‬ ‫لكن‬ , )
. ‫الكلي‬ ‫في‬ ‫حصاوي‬ ‫تكوين‬ ‫علي‬ ‫بيساعد‬ ‫ألنه‬ , ‫الجرعة‬ ‫تقلل‬ ‫أو‬ , ‫حصاوي‬ ‫أو‬
**********************************
(‫لب‬‫الق‬‫لمرضي‬ ‫مسكن‬ ‫أفضل‬)
 Trade names :
8 L.E10 tab500 mgNaprofen
7 L.E10 tab250 mgNaprofen
sulindac
Dosage
 Adult :
( ‫يوميا‬ ‫مرتين‬200 mg - 150 mg tab. )
 MAX. 400 mg dialy
Naproxen

31. 6 L.E10 tab500 mgNaprosyn
7 L.E20 tab250 mgNaprosyn
********************************************
Celebrex 200 mg 10 tab 76 L.E
Celebrex 100 mg 10 tab 49 L.E
Arythrex 100 mg 10 cap 26 L.E
Arythrex 200 mg 10 cap 36 L.E
Dosage
 Adult :
‫كل‬ ‫قرص‬12( ‫ساعة‬500 mg tab)
‫كل‬ ‫قرص‬8( ‫ساعات‬250 mg tab)
Celecoxib
Dosage
 Adult :
‫كل‬ ‫قرص‬12( ‫ساعة‬200 mg tab).
‫مع‬ ‫للنصف‬ ‫الجرعة‬ ‫تقلل‬‫الكبد‬ ‫مريض‬(100 mg. )

32. ‫مريض‬ ‫جالك‬ ‫لو‬( ‫هتكتبله‬ , ‫مسكن‬ ‫تكتبله‬ ‫وقررت‬ , ‫قلب‬naproxen‫حالة‬ ‫في‬ ‫ده‬ )
‫لفترة‬ ‫هيستخدمة‬ ‫انه‬‫قصيرة‬.
‫وهيستخدمه‬ ‫عالية‬ ‫بجرعات‬ ‫مسكن‬ ‫هتكتبله‬ ‫لو‬ ‫أما‬‫طويلة‬ ‫لفترة‬,‫يبقي‬
‫هتكتبله‬Celecoxib).)
***************************
‫اي‬
 Use :
1) Analegesic 2) anti pyretic
Not used as anti inflammatory .
 Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
Adverse effect Cause acute liver failure
in over dose .
Toxic dose in
paracetamol in
adult ( 10 g ) ,
child ( 5 g)
Precautions  Don’t administer to
patient with hepatic
impairement .
Pregnancy No contra-indication
Breast-feeding No contra-indication
 Trade names:
27 L.E24 tab500 mgPanadol
‫جدا‬ ‫مهم‬
2) paracetamol

33. 12 L.E24 tab500 mgAdol
8 L.E20 tab500 mgAbimol
‫أدوية‬ ‫الثالث‬‫فاتوا‬ ‫اللي‬‫منهم‬ ‫في‬Extra(EX: Panadol extra).
13.5 L.E20 tab500 mgParamol
7.5 L.E20 tab500 mgCetal
18 L.E15 tab1000 mgnovaldol
6 L.E20 tab500/100hepamol
5 L.ESyrup150 mgAbimol
4 L.ESyrup120 mgParacetamol
5.5 L.ESyrup250 mgCetal
‫في‬‫الكبد‬ ‫مريض‬(‫هو‬ ‫استخدامه‬ ‫يمكن‬ ‫الذي‬ ‫الوحيد‬ ‫الحرارة‬ ‫وخافض‬ ‫المسكن‬ ,Hepamol
tab‫مادة‬ ‫علي‬ ‫يحتوي‬ ‫ألنه‬ ‫وذلك‬ ,)methionin‫ال‬ ‫تحمي‬ ‫التي‬‫تسمم‬ ‫حدوث‬ ‫من‬ ‫كبد‬
. ‫الباراسيتامول‬
Dosage
 Adult ( ≥ 14 yrs ) :
‫قرصين‬3‫االكل‬ ‫بعد‬ ‫يوميا‬ ‫مرات‬
 ( 9 – 14 yrs ):
‫واحد‬ ‫قرص‬3‫األكل‬ ‫بعد‬ ‫يوميا‬ ‫مرات‬
 Child ( 3-6 yrs ) :
( ‫ونص‬ ‫معلقة‬syrup)3‫يوميا‬ ‫مرات‬
‫جدا‬ ‫مهم‬

34. 25 L.E30 tabCetafen
8.5 L.E20 tabMegafen
 Analgesics safe during pregnancy and breast-feeding :
Drug Safe during pregnancy during breast-
feeding
NSAID No ( avoid ) No ( avoid ) ,
Except diclofenac ,
Celecoxib ,
naproxyn ,
ketoprofen .
Paracetamol Yes ( B ) Yes ( B )
‫الخاصة‬ ‫الحاالت‬ ‫لبعض‬ ‫االمنة‬ ‫المسكنات‬:
1)‫الكلي‬ ‫مريض‬Sulindac
2)‫الكبد‬ ‫مريض‬Hepamol
3)‫الضغط‬ ‫مريض‬paracetamol
4)‫والرضع‬ ‫الحوامل‬paracetamol
5)‫المعدة‬ ‫في‬ ‫مشاكل‬ ‫عنده‬ ‫مريض‬paracetamol‫أو‬declofenac
6)‫القلب‬ ‫مريض‬( ‫قصيرة‬ ‫لفترة‬ ‫لو‬naproxyn‫طويلة‬ ‫لفترة‬ ‫لو‬ , )
Celecoxib). )
Declophenac‫مرضي‬ ‫في‬ ‫نهائي‬ ‫يفضل‬ ‫ال‬‫القلب‬‫أو‬‫األطفال‬.
Ketoprofen‫في‬ ‫يفضل‬ ‫ال‬‫األطفال‬.
Combination analgesics
Important
points

35. Several patient groups are predisposed to pseudomembraneous
candidiasis and erythematous candidiasis infection :
1) Patient taking inhaled corticosteroid .
2) Broad spectrum antibiotic .
3) Diabetic patient .
4) Patient with nutrional deficiencies
5) Patient with serous systemic disease ( leukemia ).
N.B : Advise patient who use corticosteroid inhaled to rinse their
mouth with water or brush their teeth immediately after using
inhaler.
************************************
Anti –Fungal drug
Use
 Oropharyngeal candidiasis .
 Denture stomatitis
 Angular cheilitis

36.  Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
Adverse effect Hypersensitivity.
Hypokalemia.
Precautions  Reduce dose by half in patient with
renal impairement .
 Avoid this drug with patient of
cardiac or hepatic disease .
Pregnancy Contra-indicated
Breast-feeding Contra-indicated
Drug inter-action Warfarin – calcium channels blockers –
zidovudine –phenytoin ).
 Topical anti fungal drug for candidiasis
 Trade names :
Daktarin 40 g Oral gel 33.5 L.E
Miconaz 2% 20 g Oral gel 10 L.E
Micoban 20 g Oral gel 7 L.E
. ‫يوميا‬ ‫مرتين‬ ‫دهان‬
N.B: Best used 7 days after lesion have healed .
Miconazole
‫الجرعة‬

37.  Trade names :
Nystatin 100,000
u/1ml
Oral
drops
5.5 L.E
Fungistatin 100,000
u/1ml
Oral
drops
6 L.E
mycostatin 100,000
u/1ml
Oral
drops
8.5 L.E
.‫يوميا‬ ‫مرات‬ 3 ‫بالقطارة‬ ‫مل‬ 4-3 ‫توضع‬
‫حجمها‬ ‫قطارة‬ ‫معاه‬ ‫بيكون‬1( ‫مل‬1= ‫مل‬100,000).
 N.B:
 Take before eating 30 minutes at least.
 Should be retained in mouth for few minutes before swallowing or
applied to tongue and inside of cheek .
*****************************************
Systemic anti-fungal drug
 Trade names :
Diflucan 150 mg 1 cap 48.5 L.E
Diflucan 50 mg 7 cap 95 L.E
Diflucan 5 mg syrup 95 L.E
Nystatin
‫الجرعة‬
fluconazole

38. Flucoral 150 mg 2 cap 17.5 L.E
Treflucan 150 mg 1 cap 15 L.E
Amriflucan 50 mg 7 cap 24 L.E
Amriflucan 150 mg 2 cap 9 L.E
****************************************
( Broad spectrum than fluconazole )
Sporanox 100 mg 4 cap 42 L.E
Sporanox 100 mg 14 cap 108 L.E
Dose
 Adult :
( ‫هتكون‬ ‫الجرعة‬200 mg( ‫كدة‬ ‫بعد‬ ‫يكمل‬ , ‫فقط‬ ‫يوم‬ ‫أول‬ )100 mg)
( ‫كبسولة‬ ‫يوم‬ ‫أول‬ ‫يعني‬ , ‫يوميا‬150 mg( ‫كبسولة‬ ‫ومعاها‬ )50 mg)
( ‫كبسولة‬ ‫كدة‬ ‫بعد‬ ,50 mg‫يوميا‬ ‫مرتين‬ )‫لمدة‬7–14‫أقصي‬ ‫حد‬ ‫يوم‬.
 Child ( 3 – 11 yrs) :
( 3 mg/kg/d ) , MAX. ( 50 mg dialy )
Itraconazole

39. Itranox 100 mg 4 cap 18 L.E
Itranox 100 mg 15 cap 54 L.E
Itracon 100 mg 4 cap 21.5 L.E
Itracon 100 mg 15 cap 63 L.E
‫كبسولة‬‫يوميا‬‫لمدة‬14‫يوم‬.
‫إمتصاصه‬ ‫بتزود‬ , ‫بتزيد‬ ‫لما‬ ‫المعدة‬ ‫حموضة‬ ‫ألن‬ , ‫االكل‬ ‫مع‬ ‫يأخذ‬ ‫أن‬ ‫يفضل‬
(Itraconazole. )
Fluconazole‫من‬ ‫التأثير‬ ‫في‬ ‫أقل‬Itraconazole‫علشان‬ ‫يستخدم‬ ‫لكن‬ ,
‫األعراض‬ ‫في‬ ‫أقل‬‫الجانبية‬.
‫استخدم‬ , ‫الفطريات‬ ‫ألدوية‬ ‫بالنسبة‬Topical‫استخدم‬ , ‫حاجة‬ ‫أول‬
Systemic‫الل‬ ‫الحاالت‬ ‫في‬ ‫فقط‬severe‫بتكون‬ ‫اللي‬ ‫وخصوصا‬
‫لل‬ ‫مصاحبة‬immunocompramised patient.
*************************
)Denture stomatitis)
‫التعليمات‬ ‫استخدم‬ ‫الحالة‬ ‫هذه‬ ‫بخصوص‬: ‫العالج‬ ‫إعطاء‬ ‫قبل‬ ‫التالية‬
 Advise patient to :
1) Brush palate dialy to treat the condition .
2) Clean their denture by soaking in chlorhexidine or sodium
hypochlorite for 15 minute twice dialy .
Note : hypochlorite should only be used for acrylic denture .
‫الجرعة‬
‫مهم‬

40.  Anti-fungal drug safe during pregnancy and breast-
feeding :
Drug Safe during
pregnancy
during breast-
feeding
Nystatin Yes Yes
Fluconazole No ( avoid ) Yes
Itraconazole No ( avoid ) No ( avoid )
‫أدوية‬anti-fungal‫مرضي‬ ‫مع‬ ‫ممنوعة‬‫الكبد‬ ‫و‬ ‫القلب‬. ‫نهائي‬
‫الجرعة‬ ‫هتقلل‬‫للنصف‬. ‫الكلي‬ ‫مرضي‬ ‫في‬
Important
points

41. Herpes simplex virusvaricella zoster virus
Use
 Treatment of herpes simplex virus .
 Treatment of varicella zoster virus .

42.  Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
Adverse effect Local irritation in topical cream
Allergy .
Precautions  Reduce dose in patient with
renal impairement .
Pregnancy No contra indication (acyclovir
( Category B )
Breast-feeding No contra-indication
Drug inter-action  Zidovudine – probencid
 Trade names:
Zovirax 400 mg 10 tab 33 L.E
Zovirax 400mg/5ml syrup 45 L.E
Zovirax 5% Cream 14 L.E
78 L.E35 tab400 mgAcyclovir
104 L.E35 tab800 mgAcyclovir
6.5 L.ECream10 gAcyclovir 5%
Acyclovir

43.  In case of virus :
1) Advise patient to avoid dehydration and drink a lot of water
2) Alter their diet to include soft diet .
3) Use analgesic and antimicrobial mouth wash .
**********************************************
Safe during breast-
feeding
Safe during pregnancyDrug
YesYes ( B )
Acyclovir
‫هتقلل‬‫جرعة‬acyclovir‫في‬‫مرضي‬‫الكلي‬.
Dosage
In case of herpes simplex infection :
 Adult : ( 400 mg ) 5 times dialy .
 Child : ( 40 -80 mg/kg/d ) , Max ( 1000 mg ) ‫علي‬ ‫تقسم‬5
‫جرعات‬
In case of varicella zoster :
 Adult : ( 800 mg tab ) 5 times dialy ‫أو‬ ‫أسبوع‬ ‫لمدة‬10‫أيام‬
 Child : ( 80 mg/kg/d ) , Max( 4000 mg ) ‫علي‬ ‫تقسم‬5‫جرعات‬
 ( Cream ) ‫دهان‬5‫يوميا‬ ‫مرات‬
Important
points

44.  Adverse effect _ Precautions _ Pregnancy _ Breast-feeding :
Adverse effect Sedation – hypotension –
dizziness.
Precautions  Avoid car driving .
Pregnancy Contra –indicated .
Breast-feeding Contra-indicated .
Use
 TMJ dysfunction in case of muscle
tone . ( muscle spasm )
muscle spasm

45.  Trade names :
Relaxon 250 mg 20 cap 18 L.E
Myolgin 250 mg 20 cap 16 L.E
Myofen 250 mg 20 cap 18 L.E
Relax 250 mg 20 cap 21 L.E
 Trade names :
Multi-relax 5 mg 20 tab 18 L.E
Cyclosed 10 mg 30 tab 31 L.E
3‫مرات‬‫يوميا‬‫بعد‬‫األكل‬.
*******************************************
Safe during breast-
feeding
Safe during
pregnancy
Drug
YesNo ( avoid )Chlorzoxazone
YesYes ( B )Cyclopenzaprine
Chlorzoxazone
Cyclopenzaprine
‫الجرعة‬
Important
points

46.  Adverse effect – precautions – pregnancy – breast-feeding :
Adverse effect Nephrolithiasis for dose ≥ 1 g/d
May interfere with measurement
of glucose in blood and urine
for dose ≥ 2 g/d .
Precautions  Drink a lot of water to avoid
kidney stone .
Pregnancy No contra-indication .
Breast-feeding No contra-indication .
Use
 Prevent and treatment of scurvy ( vitamin C
deficiency ) .

47.  Trade names :
C-Retad 500 mg 10 cap 9 L.E
Cevarol 500 mg 20 tab 8 L.E
C-Viton 500 mg 10 tab 4 L.E
‫الحالة‬ ‫حسب‬ ‫أو‬ ‫شهر‬ ‫لمدة‬ ‫يوميا‬ ‫واحدة‬ ‫مرة‬
*******************************************
 Trade names :
Calcium 115mg Syrup 8.5 L.E
Hi-cal 1.2 g/5ml Syrup 7 L.E
Bone-cal 500 mg 30 tab 24 L.E
Calcimate 500 mg 12 tab 6 L.E
Calcid 500 mg 30 cap 40.5 L.E
Calci-bone 1 g 20 tab 17 L.E
 Use : Hypocalcemia
 Drug inter-action : calium salt chelate with tetracycline and
thus prevent absorption .
 Adult : ‫االكل‬ ‫بعد‬ ‫يوميا‬ ‫مرة‬ ‫واحد‬ ‫قرص‬
 Child : ) ‫شراب‬ ( ‫يوميا‬ ‫مرة‬
‫الجرعة‬
Dose

48. Trade names :
Mouth washHexitol
Mouth washChlorohex
 Use : anti septic
 Adverse effect :
 brown discoloration of tongue or teeth.
 Taste disturbance ( in continous use ) .
 Precaution : don’t swallow
 Dose : 2-4 times dialy
Trade names :
H2O2 Mouth wash
Peroxyl Mouth wash
 Use : anti septic
Chlorhexidine
2%
Hydrogen peroxide

49.  Dose : 2-4 times dialy .
 N.B : Rinse mouth for 2 minutes with 15ml diluted in half
tumber of warmer water .
‫من‬ ‫كبيرة‬ ‫معلقتين‬ ‫تضيف‬ ‫يعني‬H2O2. ‫دافئ‬ ‫ماء‬ ‫كوب‬ ‫نصف‬ ‫علي‬
Mouth washOral-dene
Mouth washOrosept
Mouth washOrovex
Mouth washAnti septol
**********************************************
36 L.E30 tabAlphintern
43 L.E30 tabAmbezim
15 L.ESyrupMaxilase
27 L.E3 ampα-chemotrypsine
 Dose :
Adult : ‫بساعة‬ ‫األكل‬ ‫قبل‬ ‫يوميا‬ ‫مرات‬ 3 ‫قرص‬
‫كل‬ ‫عضل‬ ‫حقنة‬ ‫أو‬12. ‫فقط‬ ‫ثالثة‬ ‫أو‬ ‫يومين‬ ‫لمدة‬ , ‫ساعة‬
Child : 3) ‫شراب‬ ( ‫بساعة‬ ‫االكل‬ ‫قبل‬ ‫يوميا‬ ‫مرات‬
Other Mouth
wash
Anti-edematous drug

50.  Use : for oral ulcer
 Dose : ‫يوميا‬ ‫مرات‬ 3 ‫القرحة‬ ‫علي‬ ‫دهان‬
 Precaution : don’t rinse with water , drink or eat
anything for 10 minutes after application .
*********************************************
SprayB.B.C
 Use : anti septic , anti inflammatory , anesthetic .
 Precautions : don’t use with child or old age .
 Dose : ‫يوميا‬ ‫مرات‬ 3
***********************************************
SolutionClovacaine
 Use : analgesic for toothache
 Dose : ‫يوميا‬ ‫مرتين‬ ‫السنة‬ ‫علي‬ ‫دهان‬
**********************************************
 Use : inflammation of tissue result from prosthesis .
 Dose : ‫يوميا‬ ‫مرتين‬ ‫دهان‬
PaintSalivex-L
PaintSensoseal
GelJogel
Other drugs

51. CreamHydrocortisone 1%
 Use : Eczema on lips .
 Adverse effect : cause buring sensation .
 Dose : ‫فقط‬ ‫أيام‬ 7 ‫لمدة‬ ‫أتنين‬ ‫أو‬ ‫مرة‬
****************************************************
ToothpasteSensodyne
ToothpasteParodontax
ToothpasteSignals
********************************************
Denture adhesiveCorega
Denture adhesiveProtefix
Denture adhesiveY-Kelin
Tooth paste
Denture adhesive

52. ‫إيه‬ ‫من‬ ‫بيتعالج‬ ‫هو‬ ‫عارف‬ ‫تبقي‬ ‫المريض‬ ‫مع‬ ‫دي‬ ‫األدوية‬ ‫تشوف‬ ‫لما‬ ‫علشان‬‫؟‬
‫وقاله‬ ‫كتبه‬ ‫الدكتور‬ ‫إن‬ ‫غير‬ ‫ليه‬ ‫ده‬ ‫الدواء‬ ‫بياخد‬ ‫هو‬ ‫عارفة‬ ‫مش‬ ‫بتبقي‬ ‫كتير‬ ‫ناس‬ ‫في‬ ‫ألن‬
‫علطول‬ ‫عليه‬ ‫يمشي‬. ‫شغل‬ ‫تبدأ‬ ‫ما‬ ‫قبل‬ ‫الالزمة‬ ‫اإلحتياطات‬ ‫عارف‬ ‫تبقي‬ ‫وبالتالي‬ ,
‫وتسبب‬ ‫اللثة‬ ‫علي‬ ‫بتأثر‬ ‫منهم‬ ‫أدوية‬ ‫فيه‬ ‫إن‬ ‫غير‬ ‫ده‬hyperplasia‫دلوقتي‬ ‫هتقرأ‬ ‫ما‬ ‫زي‬
‫إستخداما‬ ‫األكثر‬ ‫أو‬ ‫أشهرهم‬ ‫دول‬ ‫بس‬ , ‫كتير‬ ‫أدوية‬ ‫في‬ , ‫طبعا‬ ‫األدوية‬ ‫كل‬ ‫مش‬ ‫دي‬ ‫بس‬
(‫س‬ ‫تسبب‬ ‫التي‬ ‫األدوية‬‫الدم‬ ‫في‬ ‫يولة‬)
Tab75 mgAspocid
Tab100 mgAspirin protect
Tab75 mgAggrex
Systemic drug
Anti- platelets
(aspirin )

53. Tab5 mgMarevan
Tab5 mgCoumadin
Tab5 mgMarivanil
Tab5 mgHaemofarin
Anti coagulant
(Warfarin )

54. (t Failure DrugrHea)
Tab.25 mgLanoxin
Tab.25 mgcardixin
)Anti Anginal Drug)
)gingival hyperplasiaCause)
Cap10 mgAdalat
Tab20 mgAdalat retard
Tab30 mgAdalat L.A
Cap10 mgEpilat
Cap20 mgEpilat retard
Digitals
Nifedipine

55. Dinitra 5 mg Tab
Nitrates

56. SprayNitrolingual
TabNitroglycerine
)Anti Hypertensive Drug(
Ca channels blocker
TabMinipress
Tab250 mgAldomet
Tab250 mgEpidopa
Tab250 mgMethyldopa
Nitroglycerine
Prazosine
methyldopa

57. TabConcor 10 plus
TabCocor 5 plus
TabBistal plus
)xerostomia( cause
Tab40 mgLasix
Tab20 mgLafurex
Tab40 mgFurosemide
BB+Diuretics
Furosemide

59. ( Anti Epilepsy Drug)
)Gingival hyperplasiacause(
Cap100 mgIpanten
Cap100 mgEpanutin
cap100 mgPhenytoin
Tab200 mgDepakine
Cap300 mgConvulex
Tab500 mgvalpokine
Phenytoin
Na
Valporate

60. )How to deal with medical compermised patient)
‫بعض‬ ‫دي‬‫وأشهر‬‫و‬ ‫العيادة‬ ‫في‬ ‫معاك‬ ‫بتحصل‬ ‫اللي‬ ‫المواقف‬‫إز‬‫عليها‬ ‫تتغلب‬ ‫اي‬
1)( ‫السكر‬ ‫غيبوبة‬ : ‫األولي‬ ‫الحالة‬Diabetic coma)
 Signs /symptoms :
1) Mood change ( confusion )
2) Sweating ( ‫غزير‬ ‫عرق‬ )
3) Increased heart rate ( ‫هتالقي‬‫المريض‬‫بينهج‬‫بسبب‬‫زيادة‬‫معدل‬‫ضربات‬‫القلب‬ )
4) Coma
‫السبب‬:
‫إما‬hyperglycemia‫أو‬hypoglycemia.
( ‫سكر‬ ‫نقص‬ ‫أنها‬ ‫علي‬ ‫هتعالجها‬ ‫الحالتين‬ ‫فكال‬hypoglycemia‫ألنها‬ )
‫األخطر‬‫إلي‬ ‫تؤدي‬ ‫وقد‬ ,‫المريض‬ ‫وفاة‬. ‫بسرعة‬ ‫عالجها‬ ‫يتم‬ ‫لم‬ ‫لو‬
‫العالج‬:
1)Hypoglycemia:
a). ‫لسانه‬ ‫تحت‬ ‫سكر‬ ‫أو‬ ‫عصير‬ ‫يشرب‬
b)( ‫محلول‬ ‫علق‬ ‫يبقي‬ ‫هيقدر‬ ‫مش‬ ‫لو‬glucose. )
c)( ‫وريد‬ ‫أو‬ ‫عضل‬ ‫حقنة‬ ‫أو‬glucagon 1mg).
2)Hyperglycemia:
( ‫الحالة‬ ‫نفس‬ ‫علي‬ ‫ظل‬ ‫المريض‬ ‫لو‬coma‫أساس‬ ‫علي‬ ‫هيتعالج‬ ‫يبقي‬ )
( ‫أنها‬hyperglycemia( ‫ياخد‬ ‫دي‬ ‫الحالة‬ ‫وفي‬ )insulin. )

61. 2( ‫الصدرية‬ ‫الذبحة‬ : ‫الثانية‬ ‫)الحالة‬angina pectoris‫القلبية‬ ‫األزمة‬ , )
)myocardial infarction: )
‫تاخد‬ ‫لما‬history‫كأنك‬ ‫صدري‬ ‫في‬ ‫ألم‬ ‫بيجيلي‬ ‫هيقولك‬ ‫المريض‬ ‫من‬‫طعنته‬
‫بسكين‬‫قلبه‬ ‫في‬‫بخاخ‬ ‫أو‬ ‫لساني‬ ‫تحت‬ ‫حبوب‬ ‫وباخد‬ ,(glycerle trinitrate)
 Signs/symptoms :
1) Severe chest pain ( ‫صدره‬ ‫في‬ ‫جامد‬ ‫الم‬ )
( ‫الشمال‬ ‫كتفه‬ ‫في‬ ‫هيسمع‬ ‫االلم‬left shoulder( ‫و‬ )neck. )
 Management :
1) Stop procedure ( ‫حاال‬ ‫بتعمله‬ ‫إجراء‬ ‫أي‬ ‫وقف‬ )
2) Nitroglycerine tab ( ‫اللسان‬ ‫تحت‬ ‫يوضع‬ )
‫بعد‬ ‫يكرره‬ ‫ممكن‬5. ‫كمان‬ ‫تالتة‬ ‫مرة‬ ‫يكرر‬ , ‫تحسن‬ ‫مفيش‬ ‫لو‬ ‫دقائق‬
‫هتكون‬ ‫ألنها‬ ‫حاال‬ ‫اإلسعاف‬ ‫إطلب‬ , ‫الثالثة‬ ‫المرة‬ ‫بعد‬ ‫تحسن‬ ‫مفيش‬ ‫لو‬
)myocardial infarction‫حقنة‬ ‫ياخد‬ ‫علشان‬ ‫حاال‬ ‫المستشفي‬ ‫يدخل‬ ‫والزم‬ )
morphine). ‫الالزمة‬ ‫االجراءت‬ ‫باقي‬ ‫ويتعمل‬ , )
‫لل‬ ‫التجارية‬ ‫األسماء‬glyceryle trinitrate:
(nitrostat _ angised _ Nitrolingual spray)
******************************
3)( ‫الحساسية‬ : ‫الثالثة‬ ‫الحالة‬Allergy)
 Signs/symptoms :
‫المريض‬ ‫هتالقي‬ ‫البنج‬ ‫حقنة‬ ‫بعد‬‫أحمر‬ ‫وشه‬‫حصل‬ ‫أو‬‫انتفاخات‬. ‫المريض‬ ‫وجه‬ ‫في‬
 Management : Avil 45 mg I.M ( ‫عضل‬ ‫حقنة‬ )

62. 4): ‫الرابعة‬ ‫الحالة‬‫تشنجات‬(disorder-Seizure)
 Signs/symptoms :
1) Seizure ( ‫أسنانه‬ ‫علي‬ ‫وبيجز‬ ‫تشنجات‬ ‫نوبة‬ )
2) Tonic – clonic movement of trunk extremeties .
3) Vomiting .
4) Loss of consciousness .
 Management : valium 5 mg I.M ( ‫عضل‬ ‫حقنة‬ )
*****************************
5)( : ‫الخامسة‬ ‫الحالة‬anaphylactic shock)
‫بعد‬ ‫معاك‬ ‫تحصل‬ ‫ممكن‬‫ما‬‫حيوي‬ ‫مضاد‬ ‫حقنة‬ ‫تدي‬‫ك‬prophylaxis‫تبدأ‬ ‫ما‬ ‫قبل‬
. ‫شغل‬
 Signs/symptoms :
1) Urticaria-itching ( ‫الجلد‬ ‫في‬ ‫وهرش‬ ‫إحمرار‬ )
2) Abdominal pain ( ‫المعده‬ ‫في‬ ‫ألم‬ )
3) Pallor , sweating ( ‫ويعرق‬ ‫يدبل‬ ‫وشه‬ )
4) Angio-edema
( ‫التنفس‬ ‫في‬ ‫ضيق‬ ‫ويعمل‬ ‫الحلق‬ ‫في‬ ‫يحصل‬ ‫ممكن‬ ‫انتفاخ‬wheeze due to
bronchospasm. )
5) Loss of consciousness
‫وممكن‬ ‫الوعي‬ ‫يفقد‬ ‫المريض‬‫يموت‬‫بسرعة‬ ‫ملحقتوش‬ ‫لو‬.
 Management :
1) Lay patient with his leg raised to increase cerebral
blood flow .
2) ( Adrenaline 1:1000 I.M / S.C ) ‫الجلد‬ ‫تحت‬ ‫أو‬ ‫عضل‬ ‫حقنة‬
)‫تغلط‬ ‫إياك‬‫وتعطيها‬‫وريد‬(
‫كل‬ ‫تكرر‬5‫مفيش‬ ‫لو‬ , ‫دقائق‬improvement‫أقصي‬ ‫لحد‬(1.5 ml‫يعني‬ )3. ‫بس‬ ‫مرات‬
3) Dexamethasone 8 mg I.M ‫عضل‬ ‫حقنة‬) )
‫أقراص‬ ‫للمريض‬ ‫هتكتب‬ ‫كده‬ ‫بعد‬Dexamethasone(deltasone .75mg tab)
‫يوم‬ ‫كل‬ ‫هياخد‬‫قرصين‬‫اليوم‬ ‫في‬‫والثالث‬ ‫الثاني‬‫كده‬ ‫وبعد‬ ,‫قرص‬‫اليوم‬ ‫في‬ ‫يوميا‬ ‫واحد‬‫الرابع‬
‫والسادس‬ ‫والخامس‬‫تمنع‬ ‫علشان‬ ‫كده‬ ‫بتعمل‬ ‫انت‬ ( . ‫العالج‬ ‫توقف‬ ‫كده‬ ‫بعد‬ ,recurrance)

63. 4)( ‫نزيف‬ : ‫الرابعة‬ ‫الحالة‬leedingB)
. ‫الخلع‬ ‫مكان‬ ‫من‬ ‫بينزف‬ ‫أنه‬ ‫يقولك‬ ‫يكلمك‬ ‫أو‬ , ‫نزيف‬ ‫يحصله‬ ‫المريض‬ ‫تخلع‬ ‫ما‬ ‫بعد‬ ‫ممكن‬
 Management :
( ‫حقنة‬ ‫هياخد‬Haemostop 250 mg‫بعد‬ ‫تكرر‬ ‫وممكن‬ , ‫عضل‬ ‫أو‬ ‫وريد‬ )
6. ‫النزيف‬ ‫أستمر‬ ‫لو‬ ‫ساعات‬
‫كل‬ ‫أقراص‬ ‫ويكمل‬8( ‫ساعات‬tabHaemostop 500 mg)‫ما‬ ‫لحد‬
. ‫النزيف‬ ‫يوقف‬
. ‫الجرح‬ ‫بيها‬ ‫ويقفل‬ ‫قطن‬ ‫قطعة‬ ‫علي‬ ‫الحقنة‬ ‫يكسر‬ ‫كمان‬ ‫ممكن‬
 Kapron 500 mg amp ) ‫السابقة‬ ‫الوظيفة‬ ‫نفس‬ )
 Kapron 500 mg tab
N.B: may cause intravascular thrombosis in over dose .
**********************************
 Antibiotic prophylaxis for dental patient at risk for
infection
 Cardiac condition need prophylaxis :
1) Prosthetic cardiac valve
2) Previous infection endocarditis
3) Congenital heart disease
4) Cardiac transplantation recipient who develop cardiac
valvulopathy .

64. 60 minutes before procedure-Single dose 30
ChildrenAdultAgent /drugSituation
50 mg/kg2 gAmoxicillinOral
50 mg/kg2 g
1 g
Ampicillin
Ceftriaxone / cefazoline
I.M / I.V
20 mg/kg
15 mg/kg
15 mg/kg
600 mg
500 mg
500 mg
Clindamycin
Azithromycin
Clarithromycin
Allergic to
penicillin ( oral)
20 mg/kg600 mgClindamycinAllergic to
penicillin ( I.M/I.V)
(‫بالجدول‬ ‫الموجودة‬ ‫لألدوية‬ ‫التجارية‬ ‫األسماء‬)
1) Azithromycin
Aazerolid 500 mg Tab
Zithromax 250 mg Cap
2) Cefazoline
Cefamezine 1 g Vial
3) Clarithromycin
Klacid 500 mg Tab
Clarithro 500 mg Tab
Klarimix 500 mg Tab
. ‫المذكرة‬ ‫في‬ ‫سابقا‬ ‫ذكرها‬ ‫تم‬ ‫األدوية‬ ‫باقي‬

65. (‫املعلومات‬ ‫مصادر‬)
1)‫للمعلومات‬ ‫ية‬‫يس‬‫ئ‬‫ر‬‫ال‬ ‫املصادر‬:
 Essential drug , sophi pilon .
Drug dictionary for dentistry , J.G Meechan , R.A
Seymour ( oxford university press )
2)‫من‬ ‫يطة‬‫بس‬‫ل‬‫ا‬ ‫املعلومات‬ ‫بعض‬:
 Drug prescribing for dentistry , third edition ,
( Scottish dental clinical effectiveness programme ).
 Pharmacology book , DR/ Nabila M.Kamal
( faculty of dentistry , October 6 university )
A.B.C of drug , third edition , DR/ Ahmed abd elmeged
Burkets oral medicine , 11 edition , Greenberg ,
Click , Ship .
 ‫االسنان‬ ‫أطباء‬ ‫جروبات‬
3)‫نشو‬‫مل‬‫ا‬ ‫للمقال‬ ‫طبقا‬ ‫الرضع‬‫و‬ ‫امل‬‫و‬‫احل‬ ‫عيل‬ ‫وخطورهتا‬ ‫ية‬‫و‬‫د‬‫ال‬ ‫اجعة‬‫ر‬‫م‬ ‫مت‬‫اجملةل‬ ‫يف‬ ‫ر‬
( ‫يكية‬‫ر‬‫م‬‫ال‬ ‫العلمية‬journal of American Dental Association)‫حتت‬
‫ان‬‫و‬‫عن‬(pregnancy , breast-feeding and drugs used in dentistry)
( ‫ملظمة‬ ‫اخلاضع‬‫و‬F.D.AU.S. )